6tmn - Revision history

OCA at 10:18, 22 May 2024

2024-05-22T10:18:31Z

←Older revision		Revision as of 10:18, 22 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6tmn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TMN FirstGlance]. <br>		<table><tr><td colspan='2'>[[6tmn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TMN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0PI:N-[(2R,4S)-4-HYDROXY-2-(2-METHYLPROPYL)-4-OXIDO-7-OXO-9-PHENYL-3,8-DIOXA-6-AZA-4-PHOSPHANONAN-1-OYL]-L-LEUCINE'>0PI</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0PI:N-[(2R,4S)-4-HYDROXY-2-(2-METHYLPROPYL)-4-OXIDO-7-OXO-9-PHENYL-3,8-DIOXA-6-AZA-4-PHOSPHANONAN-1-OYL]-L-LEUCINE'>0PI</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tmn OCA], [https://pdbe.org/6tmn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tmn RCSB], [https://www.ebi.ac.uk/pdbsum/6tmn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tmn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tmn OCA], [https://pdbe.org/6tmn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tmn RCSB], [https://www.ebi.ac.uk/pdbsum/6tmn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tmn ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:19, 24 November 2022

2022-11-24T10:19:14Z

←Older revision		Revision as of 10:19, 24 November 2022
Line 1:		Line 1:

	==Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond==		==Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond==
-	<StructureSection load='6tmn' size='340' side='right' caption='[[6tmn]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='6tmn' size='340' side='right'caption='[[6tmn]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6tmn]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~'bacillus_thermoproteolyticus' 'bacillus~~ thermoproteolyticus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6TMN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6tmn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TMN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0PI:N-[(2R,4S)-4-HYDROXY-2-(2-METHYLPROPYL)-4-OXIDO-7-OXO-9-PHENYL-3,8-DIOXA-6-AZA-4-PHOSPHANONAN-1-OYL]-L-LEUCINE'>0PI</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0PI:N-[(2R,4S)-4-HYDROXY-2-(2-METHYLPROPYL)-4-OXIDO-7-OXO-9-PHENYL-3,8-DIOXA-6-AZA-4-PHOSPHANONAN-1-OYL]-L-LEUCINE'>0PI</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tmn OCA], [https://pdbe.org/6tmn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tmn RCSB], [https://www.ebi.ac.uk/pdbsum/6tmn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tmn ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6tmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tmn OCA], [~~http~~://pdbe.org/6tmn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6tmn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6tmn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6tmn ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.	+	[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tm/6tmn_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tm/6tmn_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 31:		Line 30:

	==See Also==		==See Also==
-	*[[Thermolysin\|Thermolysin]]	+	*[[Thermolysin 3D structures\|Thermolysin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus thermoproteolyticus]]		[[Category: Bacillus thermoproteolyticus]]
-	[[Category: ~~Thermolysin~~]]	+	[[Category: Large Structures]]
-	[[Category: Holden~~, H M~~]]	+	[[Category: Holden HM]]
-	[[Category: Matthews~~, B W~~]]	+	[[Category: Matthews BW]]
-	[[Category: Tronrud~~, D E]]~~	+	[[Category: Tronrud DE]]
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Metalloproteinase~~]]	+

OCA at 11:55, 5 August 2016

2016-08-05T11:55:21Z

←Older revision		Revision as of 11:55, 5 August 2016
Line 1:		Line 1:
		+
	==Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond==		==Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond==
	<StructureSection load='6tmn' size='340' side='right' caption='[[6tmn]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='6tmn' size='340' side='right' caption='[[6tmn]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6tmn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_thermoproteolyticus Bacillus~~ thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TMN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6tmn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/'bacillus_thermoproteolyticus' 'bacillus thermoproteolyticus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TMN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0PI:N-[(2R,4S)-4-HYDROXY-2-(2-METHYLPROPYL)-4-OXIDO-7-OXO-9-PHENYL-3,8-DIOXA-6-AZA-4-PHOSPHANONAN-1-OYL]-L-LEUCINE'>0PI</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0PI:N-[(2R,4S)-4-HYDROXY-2-(2-METHYLPROPYL)-4-OXIDO-7-OXO-9-PHENYL-3,8-DIOXA-6-AZA-4-PHOSPHANONAN-1-OYL]-L-LEUCINE'>0PI</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tmn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=6tmn RCSB], [http://www.ebi.ac.uk/pdbsum/6tmn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tmn OCA], [http://pdbe.org/6tmn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tmn RCSB], [http://www.ebi.ac.uk/pdbsum/6tmn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tmn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=6tmn ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 6tmn" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 18:36, 25 December 2014

2014-12-25T18:36:26Z

←Older revision		Revision as of 18:36, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tmn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=6tmn RCSB], [http://www.ebi.ac.uk/pdbsum/6tmn PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tmn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=6tmn RCSB], [http://www.ebi.ac.uk/pdbsum/6tmn PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 16:51, 10 December 2014

2014-12-10T16:51:56Z

←Older revision		Revision as of 16:51, 10 December 2014
Line 1:		Line 1:
-	[[~~Image~~:6tmn.~~png\|left~~\|200px]]	+	==Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond==
		+	<StructureSection load='6tmn' size='340' side='right' caption='[[6tmn]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6tmn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TMN FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0PI:N-[(2R,4S)-4-HYDROXY-2-(2-METHYLPROPYL)-4-OXIDO-7-OXO-9-PHENYL-3,8-DIOXA-6-AZA-4-PHOSPHANONAN-1-OYL]-L-LEUCINE'>0PI</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tmn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=6tmn RCSB], [http://www.ebi.ac.uk/pdbsum/6tmn PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tm/6tmn_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The mode of binding to thermolysin of the ester analog Cbz-GlyP-(O)-Leu-Leu has been determined by x-ray crystallography and shown to be virtually identical (maximum difference 0.2 angstrom) with the corresponding peptide analog Cbz-GlyP-(NH)-Leu-Leu. The two inhibitors provide a matched pair of enzyme-inhibitor complexes that differ by 4.1 kilocalories per mole in intrinsic binding energy but are essentially identical except for the presence or absence of a specific hydrogen bond.

-	~~{{STRUCTURE_6tmn\| PDB=6tmn \| SCENE= }}~~	+	Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond.,Tronrud DE, Holden HM, Matthews BW Science. 1987 Jan 30;235(4788):571-4. PMID:3810156<ref>PMID:3810156</ref>

-	~~===Structures~~ of ~~two thermolysin-inhibitor complexes that differ by a single hydrogen bond===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_3810156}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[6tmn]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA].~~	+

	==See Also==		==See Also==
	*[[Thermolysin\|Thermolysin]]		*[[Thermolysin\|Thermolysin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:003810156<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus thermoproteolyticus]]		[[Category: Bacillus thermoproteolyticus]]
	[[Category: Thermolysin]]		[[Category: Thermolysin]]
-	[[Category: Holden, H M.]]	+	[[Category: Holden, H M]]
-	[[Category: Matthews, B W.]]	+	[[Category: Matthews, B W]]
-	[[Category: Tronrud, D E.]]	+	[[Category: Tronrud, D E]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Metalloproteinase]]		[[Category: Metalloproteinase]]

OCA at 20:04, 20 October 2012

2012-10-20T20:04:16Z

←Older revision		Revision as of 20:04, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[6tmn]] is a 1 chain structure ~~of [[Thermolysin]]~~ with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA].	+	[[6tmn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA].

	==See Also==		==See Also==

OCA: Protected "6tmn" [edit=sysop:move=sysop]

2012-07-27T09:19:12Z

Protected "6tmn" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:19, 27 July 2012

OCA at 09:19, 27 July 2012

2012-07-27T09:19:10Z

←Older revision		Revision as of 09:19, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:6tmn.png\|left\|200px]]		[[Image:6tmn.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_6tmn", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_6tmn\| PDB=6tmn \| SCENE= }}		{{STRUCTURE_6tmn\| PDB=6tmn \| SCENE= }}

-	===~~STRUCTURES OF TWO THERMOLYSIN~~-~~INHIBITOR COMPLEXES THAT DIFFER BY A SINGLE HYDROGEN BOND~~===	+	===Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_3810156}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 3810156 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_3810156}}		{{ABSTRACT_PUBMED_3810156}}

	==About this Structure==		==About this Structure==
-	~~6TMN~~ is a ~~2 chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA].	+	[[6tmn]] is a 1 chain structure of [[Thermolysin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA].
		+
		+	==See Also==
		+	*[[Thermolysin\|Thermolysin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~3810156~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:003810156</ref><references group="xtra"/>
	[[Category: Bacillus thermoproteolyticus]]		[[Category: Bacillus thermoproteolyticus]]
	[[Category: Thermolysin]]		[[Category: Thermolysin]]
Line 29:		Line 20:
	[[Category: Matthews, B W.]]		[[Category: Matthews, B W.]]
	[[Category: Tronrud, D E.]]		[[Category: Tronrud, D E.]]
-		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Sep 21 21~~:~~04:07 2009''~~	+	[[Category: Metalloproteinase]]

OCA at 18:04, 21 September 2009

2009-09-21T18:04:08Z

←Older revision		Revision as of 18:04, 21 September 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	6TMN is a 2 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA].	+	6TMN is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:3810156</ref><references group="xtra"/>		<ref group="xtra">PMID:3810156</ref><references group="xtra"/>
		+	[[Category: Bacillus thermoproteolyticus]]
	[[Category: Thermolysin]]		[[Category: Thermolysin]]
	[[Category: Holden, H M.]]		[[Category: Holden, H M.]]
Line 29:		Line 30:
	[[Category: Tronrud, D E.]]		[[Category: Tronrud, D E.]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Feb 18 02~~:41:00 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 21:04:07 2009''

OCA at 00:41, 18 February 2009

2009-02-18T00:41:02Z

←Older revision		Revision as of 00:41, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	6TMN is a ~~[[Single protein]]~~ structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA].	+	6TMN is a 2 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TMN OCA].

	==Reference==		==Reference==
-	~~Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond., Tronrud DE, Holden HM, Matthews BW, Science. 1987 Jan 30;235(4788):571-4.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/3810156 3810156]~~	+	<ref group="xtra">PMID:3810156</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Thermolysin]]		[[Category: Thermolysin]]
	[[Category: Holden, H M.]]		[[Category: Holden, H M.]]
Line 30:		Line 29:
	[[Category: Tronrud, D E.]]		[[Category: Tronrud, D E.]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Jul 3 14~~:26:~~54 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:41:00 2009''