7ae1 - Revision history

OCA at 07:44, 1 May 2024

2024-05-01T07:44:26Z

←Older revision		Revision as of 07:44, 1 May 2024
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-	====	+	==Cryo-EM structure of human RNA Polymerase III elongation complex 1==
-	<StructureSection load='7ae1' size='340' side='right'caption='[[7ae1]]' scene=''>	+	<StructureSection load='7ae1' size='340' side='right'caption='[[7ae1]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7ae1]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AE1 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ae1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ae1 OCA], [https://pdbe.org/7ae1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ae1 RCSB], [https://www.ebi.ac.uk/pdbsum/7ae1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ae1 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ae1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ae1 OCA], [https://pdbe.org/7ae1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ae1 RCSB], [https://www.ebi.ac.uk/pdbsum/7ae1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ae1 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/RPC9_HUMAN RPC9_HUMAN] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity). Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
		+
		+	==See Also==
		+	*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Girbig M]]
		+	[[Category: Misiaszek AD]]
		+	[[Category: Mueller CW]]
		+	[[Category: Vorlaender MK]]

OCA at 11:09, 3 February 2021

2021-02-03T11:09:25Z

←Older revision		Revision as of 11:09, 3 February 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7ae1 ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='7ae1' size='340' side='right'caption='[[7ae1]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ae1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ae1 OCA], [https://pdbe.org/7ae1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ae1 RCSB], [https://www.ebi.ac.uk/pdbsum/7ae1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ae1 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 05:24, 6 January 2021

2021-01-06T05:24:48Z

←Older revision		Revision as of 05:24, 6 January 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7ae1 is ON HOLD	+	The entry 7ae1 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 04:56, 9 December 2020

2020-12-09T04:56:32Z

←Older revision		Revision as of 04:56, 9 December 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7ae1 is ON HOLD ~~until Paper Publication~~	+	The entry 7ae1 is ON HOLD

	Authors:		Authors:

OCA at 06:31, 21 October 2020

2020-10-21T06:31:35Z

←Older revision		Revision as of 06:31, 21 October 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7ae1 is ON HOLD	+	The entry 7ae1 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7ae1" [edit=sysop:move=sysop]

2020-09-23T08:46:56Z

Protected "7ae1" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:46, 23 September 2020

OCA: New page: '''Unreleased structure''' The entry 7ae1 is ON HOLD Authors: Description: Category: Unreleased Structures

2020-09-23T08:46:54Z

New page: '''Unreleased structure''' The entry 7ae1 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7ae1 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]