7bie - Revision history

OCA at 12:28, 1 February 2024

2024-02-01T12:28:56Z

←Older revision		Revision as of 12:28, 1 February 2024
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	<StructureSection load='7bie' size='340' side='right'caption='[[7bie]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='7bie' size='340' side='right'caption='[[7bie]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7bie]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BIE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7bie]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BIE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bie OCA], [https://pdbe.org/7bie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bie RCSB], [https://www.ebi.ac.uk/pdbsum/7bie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bie ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bie OCA], [https://pdbe.org/7bie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bie RCSB], [https://www.ebi.ac.uk/pdbsum/7bie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bie ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B2J0I0_NOSP7 B2J0I0_NOSP7]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Laier, I]]
-	[[Category: Lee, X Y]]
-	[[Category: Mylemans, B]]
-	[[Category: Voet, A R.D]]
-	[[Category: De novo protein]]
	[[Category: Synthetic construct]]		[[Category: Synthetic construct]]
		+	[[Category: Laier I]]
		+	[[Category: Lee XY]]
		+	[[Category: Mylemans B]]
		+	[[Category: Voet ARD]]

OCA at 05:51, 6 October 2021

2021-10-06T05:51:21Z

←Older revision		Revision as of 05:51, 6 October 2021
Line 1:		Line 1:

	==Crystal structure of nvWrap-T, a 7-bladed symmetric propeller==		==Crystal structure of nvWrap-T, a 7-bladed symmetric propeller==
-	<StructureSection load='7bie' size='340' side='right'caption='[[7bie]]' scene=''>	+	<StructureSection load='7bie' size='340' side='right'caption='[[7bie]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BIE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7bie]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BIE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bie OCA], [https://pdbe.org/7bie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bie RCSB], [https://www.ebi.ac.uk/pdbsum/7bie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bie ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bie OCA], [https://pdbe.org/7bie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bie RCSB], [https://www.ebi.ac.uk/pdbsum/7bie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bie ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	[Formula: see text]-Propeller proteins are common natural disc-like pseudo-symmetric proteins that contain multiple repeats ('blades') each consisting of a 4-stranded anti-parallel [Formula: see text]-sheet. So far, 4- to 12-bladed [Formula: see text]-propellers have been discovered in nature showing large functional and sequential variation. Using computational design approaches, we created perfectly symmetric [Formula: see text]-propellers out of natural pseudo-symmetric templates. These proteins are useful tools to study protein evolution of this very diverse fold. While the 7-bladed architecture is the most common, no symmetric 7-bladed monomer has been created and characterized so far. Here we describe such a engineered protein, based on a highly symmetric natural template, and test the effects of circular permutation on its stability. Geometrical analysis of this protein and other artificial symmetrical proteins reveals no systematic constraint that could be used to help in engineering of this fold, and suggests sequence constraints unique to each [Formula: see text]-propeller sub-family.
		+
		+	Structure and stability of the designer protein WRAP-T and its permutants.,Mylemans B, Lee XY, Laier I, Helsen C, Voet ARD Sci Rep. 2021 Sep 22;11(1):18867. doi: 10.1038/s41598-021-98391-0. PMID:34552189<ref>PMID:34552189</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7bie" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Laier I]]	+	[[Category: Laier, I]]
-	[[Category: Lee XY]]	+	[[Category: Lee, X Y]]
-	[[Category: Mylemans B]]	+	[[Category: Mylemans, B]]
-	[[Category: Voet ~~ARD~~]]	+	[[Category: Voet, A R.D]]
		+	[[Category: De novo protein]]
		+	[[Category: Synthetic construct]]

OCA at 06:48, 22 September 2021

2021-09-22T06:48:45Z

←Older revision		Revision as of 06:48, 22 September 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7bie is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of nvWrap-T, a 7-bladed symmetric propeller==
-		+	<StructureSection load='7bie' size='340' side='right'caption='[[7bie]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BIE FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bie OCA], [https://pdbe.org/7bie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bie RCSB], [https://www.ebi.ac.uk/pdbsum/7bie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bie ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Laier I]]
		+	[[Category: Lee XY]]
		+	[[Category: Mylemans B]]
		+	[[Category: Voet ARD]]

OCA at 08:33, 17 February 2021

2021-02-17T08:33:07Z

←Older revision		Revision as of 08:33, 17 February 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7bie is ON HOLD	+	The entry 7bie is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7bie" [edit=sysop:move=sysop]

2021-01-20T06:42:02Z

Protected "7bie" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:42, 20 January 2021

OCA: New page: '''Unreleased structure''' The entry 7bie is ON HOLD Authors: Description: Category: Unreleased Structures

2021-01-20T06:42:01Z

New page: '''Unreleased structure''' The entry 7bie is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7bie is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]