7brc - Revision history

OCA at 15:27, 29 November 2023

2023-11-29T15:27:08Z

←Older revision		Revision as of 15:27, 29 November 2023
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	==Crystal structure of the TMK3 LRR domain==		==Crystal structure of the TMK3 LRR domain==
-	<StructureSection load='7brc' size='340' side='right'caption='[[7brc]]' scene=''>	+	<StructureSection load='7brc' size='340' side='right'caption='[[7brc]], [[Resolution\|resolution]] 2.06Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BRC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=7BRC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7brc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BRC FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7brc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7brc OCA], [~~http~~://pdbe.org/7brc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7brc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7brc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7brc ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.06Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7brc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7brc OCA], [https://pdbe.org/7brc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7brc RCSB], [https://www.ebi.ac.uk/pdbsum/7brc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7brc ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/TMK3_ARATH TMK3_ARATH] Involved in auxin signal transduction and cell expansion and proliferation regulation (PubMed:23613767).<ref>PMID:23613767</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Transmembrane kinases (TMKs) are members of the plant receptor-like kinase (RLK) family. TMKs are characterized by an extracellular leucine-rich-repeat (LRR) domain, a single transmembrane region and a cytoplasmic kinase domain. TMKs have been shown to act as critical modulators of cell expansion and cell proliferation. Here, the crystal structure of the extracellular domain of TMK3 (TMK3-ECD) was determined to a resolution of 2.06 A, with an Rwork of 17.69% and an Rfree of 20.58%. Similar to the extracellular domain of TMK1, the TMK3-ECD structure contains two solenoids with 13 LRRs and a non-LRR region (316-364) between the tenth and 11th LRRs. A comparison of TMK3-ECD with other LRR-RLKs that contain a non-LRR region indicates that the non-LRR region plays a critical role in structural integrity and may contribute to ligand interactions. The non-LRR region of TMK3-ECD is characterized by two disulfide bonds that may have critical biological implications.
		+
		+	Crystal structure of the extracellular domain of the receptor-like kinase TMK3 from Arabidopsis thaliana.,Chen H, Kong Y, Chen J, Li L, Li X, Yu F, Ming Z Acta Crystallogr F Struct Biol Commun. 2020 Aug 1;76(Pt 8):384-390. doi:, 10.1107/S2053230X20010122. Epub 2020 Jul 29. PMID:32744250<ref>PMID:32744250</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7brc" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Chen H]]		[[Category: Chen H]]

OCA at 06:24, 19 August 2020

2020-08-19T06:24:34Z

←Older revision		Revision as of 06:24, 19 August 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 7brc is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of the TMK3 LRR domain==
-		+	<StructureSection load='7brc' size='340' side='right'caption='[[7brc]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BRC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7BRC FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7brc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7brc OCA], [http://pdbe.org/7brc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7brc RCSB], [http://www.ebi.ac.uk/pdbsum/7brc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7brc ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Chen H]]
		+	[[Category: Chen J]]
		+	[[Category: Kong YQ]]
		+	[[Category: Li L]]
		+	[[Category: Li XS]]
		+	[[Category: Ming ZH]]
		+	[[Category: Yu F]]

OCA at 05:23, 3 June 2020

2020-06-03T05:23:11Z

←Older revision		Revision as of 05:23, 3 June 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7brc is ON HOLD	+	The entry 7brc is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7brc" [edit=sysop:move=sysop]

2020-04-01T07:57:11Z

Protected "7brc" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:57, 1 April 2020

OCA: New page: '''Unreleased structure''' The entry 7brc is ON HOLD Authors: Description: Category: Unreleased Structures

2020-04-01T07:57:09Z

New page: '''Unreleased structure''' The entry 7brc is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7brc is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]