7bta - Revision history

OCA at 15:32, 29 November 2023

2023-11-29T15:32:10Z

←Older revision		Revision as of 15:32, 29 November 2023
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	<StructureSection load='7bta' size='340' side='right'caption='[[7bta]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='7bta' size='340' side='right'caption='[[7bta]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7bta]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BTA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=7BTA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7bta]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BTA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GDP:GUANOSINE~~-~~5-DIPHOSPHATE'>GDP</scene>~~, ~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~RHEB, RHEB2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=5~~&id~~=~~9606 HUMAN])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7bta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bta OCA], [~~http~~://pdbe.org/7bta PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7bta RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7bta PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7bta ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bta OCA], [https://pdbe.org/7bta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bta RCSB], [https://www.ebi.ac.uk/pdbsum/7bta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bta ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/RHEB_HUMAN RHEB_HUMAN]] Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.<ref>PMID:12271141</ref> <ref>PMID:12869586</ref> <ref>PMID:15340059</ref> <ref>PMID:15854902</ref> <ref>PMID:16098514</ref> <ref>PMID:20381137</ref>	+	[https://www.uniprot.org/uniprot/RHEB_HUMAN RHEB_HUMAN] Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.<ref>PMID:12271141</ref> <ref>PMID:12869586</ref> <ref>PMID:15340059</ref> <ref>PMID:15854902</ref> <ref>PMID:16098514</ref> <ref>PMID:20381137</ref>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ding, J]]	+	[[Category: Ding J]]
-	[[Category: Zhang, C]]	+	[[Category: Zhang C]]
-	[[Category: Zhang, T]]	+	[[Category: Zhang T]]
-	~~[[Category: Mtorc1]]~~	+
-	~~[[Category: Rheb]]~~	+
-	~~[[Category: Signaling protein]]~~	+
-	~~[[Category: Small gtpase~~]]	+

OCA at 07:03, 30 December 2020

2020-12-30T07:03:52Z

←Older revision		Revision as of 07:03, 30 December 2020
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	==Crystal structure of Rheb D60K mutant bound to GDP==		==Crystal structure of Rheb D60K mutant bound to GDP==
-	<StructureSection load='7bta' size='340' side='right'caption='[[7bta]]' scene=''>	+	<StructureSection load='7bta' size='340' side='right'caption='[[7bta]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BTA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7BTA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7bta]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BTA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7BTA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7bta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bta OCA], [http://pdbe.org/7bta PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7bta RCSB], [http://www.ebi.ac.uk/pdbsum/7bta PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7bta ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RHEB, RHEB2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7bta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bta OCA], [http://pdbe.org/7bta PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7bta RCSB], [http://www.ebi.ac.uk/pdbsum/7bta PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7bta ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RHEB_HUMAN RHEB_HUMAN]] Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.<ref>PMID:12271141</ref> <ref>PMID:12869586</ref> <ref>PMID:15340059</ref> <ref>PMID:15854902</ref> <ref>PMID:16098514</ref> <ref>PMID:20381137</ref>
		+
		+	==See Also==
		+	*[[GTP-binding protein 3D structures\|GTP-binding protein 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ding J]]	+	[[Category: Ding, J]]
-	[[Category: Zhang C]]	+	[[Category: Zhang, C]]
-	[[Category: Zhang T]]	+	[[Category: Zhang, T]]
		+	[[Category: Mtorc1]]
		+	[[Category: Rheb]]
		+	[[Category: Signaling protein]]
		+	[[Category: Small gtpase]]

OCA at 10:17, 17 June 2020

2020-06-17T10:17:40Z

←Older revision		Revision as of 10:17, 17 June 2020
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 7bta ~~is ON HOLD~~	+	==Crystal structure of Rheb D60K mutant bound to GDP==
-		+	<StructureSection load='7bta' size='340' side='right'caption='[[7bta]]' scene=''>
-	~~Authors~~: ~~Zhang~~, C., ~~Zhang~~, T., ~~Ding~~, J.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BTA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7BTA FirstGlance]. <br>
-	~~Description: Crystal structure of Rheb D60K mutant bound to GDP~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7bta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bta OCA], [http://pdbe.org/7bta PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7bta RCSB], [http://www.ebi.ac.uk/pdbsum/7bta PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7bta ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Ding, J]]	+	__TOC__
-	[[Category: Zhang~~, T~~]]	+	</StructureSection>
-	[[Category: Zhang~~, C~~]]	+	[[Category: Large Structures]]
		+	[[Category: Ding J]]
		+	[[Category: Zhang C]]
		+	[[Category: Zhang T]]

OCA: Protected "7bta" [edit=sysop:move=sysop]

2020-04-08T05:52:37Z

Protected "7bta" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:52, 8 April 2020

OCA: New page: '''Unreleased structure''' The entry 7bta is ON HOLD Authors: Zhang, C., Zhang, T., Ding, J. Description: Crystal structure of Rheb D60K mutant bound to GDP [[Category: Unreleased Stru...

2020-04-08T05:52:36Z

New page: '''Unreleased structure''' The entry 7bta is ON HOLD Authors: Zhang, C., Zhang, T., Ding, J. Description: Crystal structure of Rheb D60K mutant bound to GDP [[Category: Unreleased Stru...

New page

'''Unreleased structure'''

The entry 7bta is ON HOLD

Authors: Zhang, C., Zhang, T., Ding, J.

Description: Crystal structure of Rheb D60K mutant bound to GDP
[[Category: Unreleased Structures]]
[[Category: Ding, J]]
[[Category: Zhang, T]]
[[Category: Zhang, C]]