OCA at 16:06, 29 November 2023

2023-11-29T16:06:36Z

←Older revision		Revision as of 16:06, 29 November 2023
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-	====	+	==Complex STRUCTURE OF TRANSCRIPTION FACTOR SghR with its COGNATE DNA==
-	<StructureSection load='7ce1' size='340' side='right'caption='[[7ce1]]' scene=''>	+	<StructureSection load='7ce1' size='340' side='right'caption='[[7ce1]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7ce1]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens] and [https://en.wikipedia.org/wiki/Agrobacterium_tumefaciens_A6 Agrobacterium tumefaciens A6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CE1 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7ce1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ce1 OCA], [~~http~~://pdbe.org/7ce1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7ce1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7ce1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7ce1 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ce1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ce1 OCA], [https://pdbe.org/7ce1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ce1 RCSB], [https://www.ebi.ac.uk/pdbsum/7ce1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ce1 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A2I4PGE9_RHIRD A0A2I4PGE9_RHIRD]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Agrobacterium tumefaciens infects various plants and causes crown gall diseases involving temporal expression of virulence factors. SghA is a newly-identified virulence factor enzymatically releasing salicylic acid from its glucoside conjugate and controlling the plant tumor development. Here we report the structural basis of SghR, a LacI-type transcription factor and highly conserved in Rhizobiaceae family, regulating the expression of SghA and involved in tumorigenesis. We identified and characterized the binding site of SghR on the promoter region of sghA, and then determined the crystal structures of apo-SghR, SghR complexed with its operator DNA and ligand sucrose, respectively. These results provide detailed insights into how SghR recognizes its cognate DNA and shed a mechanistic light on how sucrose attenuates the affinity of SghR with DNA to modulate the expression of SghA. Given the important role of SghR in mediating the signaling crosstalk during Agrobacterium infection, our results pave the way for structure-based inducer analogue design, which has potential applications for agricultural industry.
		+
		+	Structural basis of a novel repressor SghR controlling Agrobacterium infection by cross-talking to plants.,Ye F, Wang C, Fu Q, Yan XF, Bharath SR, Casanas A, Wang M, Song H, Zhang LH, Gao YG J Biol Chem. 2020 Jul 10. pii: RA120.012908. doi: 10.1074/jbc.RA120.012908. PMID:32651231<ref>PMID:32651231</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7ce1" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Agrobacterium tumefaciens]]
		+	[[Category: Agrobacterium tumefaciens A6]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Gao YG]]
		+	[[Category: Wang C]]
		+	[[Category: Yan XF]]
		+	[[Category: Ye FZ]]
		+	[[Category: Zhang LH]]

OCA at 11:51, 22 July 2020

2020-07-22T11:51:14Z

←Older revision		Revision as of 11:51, 22 July 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 7ce1 ~~is ON HOLD~~	+	====
-		+	<StructureSection load='7ce1' size='340' side='right'caption='[[7ce1]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7ce1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ce1 OCA], [http://pdbe.org/7ce1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7ce1 RCSB], [http://www.ebi.ac.uk/pdbsum/7ce1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7ce1 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA: Protected "7ce1" [edit=sysop:move=sysop]

2020-07-08T11:26:44Z

Protected "7ce1" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:26, 8 July 2020

OCA: New page: '''Unreleased structure''' The entry 7ce1 is ON HOLD Authors: Description: Category: Unreleased Structures

2020-07-08T11:26:43Z

New page: '''Unreleased structure''' The entry 7ce1 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7ce1 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

7ce1 - Revision history

OCA at 16:06, 29 November 2023

OCA at 11:51, 22 July 2020

OCA: Protected "7ce1" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7ce1 is ON HOLD Authors: Description: Category: Unreleased Structures