7ck3 - Revision history

OCA at 16:09, 29 November 2023

2023-11-29T16:09:57Z

←Older revision		Revision as of 16:09, 29 November 2023
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	<StructureSection load='7ck3' size='340' side='right'caption='[[7ck3]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='7ck3' size='340' side='right'caption='[[7ck3]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7ck3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CK3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7ck3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CK3 FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~CESA3~~, ~~ATHB, CEV1, ELI1, IXR1, RSW5, At5g05170, K2A11.4 (~~[~~https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=3702 ARATH])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ck3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ck3 OCA], [https://pdbe.org/7ck3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ck3 RCSB], [https://www.ebi.ac.uk/pdbsum/7ck3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ck3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ck3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ck3 OCA], [https://pdbe.org/7ck3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ck3 RCSB], [https://www.ebi.ac.uk/pdbsum/7ck3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ck3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CESA3_ARATH CESA3_ARATH]] Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation, especially in roots.<ref>PMID:11340179</ref> <ref>PMID:12068120</ref> <ref>PMID:12119374</ref> <ref>PMID:12713541</ref> <ref>PMID:17878302</ref> <ref>PMID:17878303</ref>	+	[https://www.uniprot.org/uniprot/CESA3_ARATH CESA3_ARATH] Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation, especially in roots.<ref>PMID:11340179</ref> <ref>PMID:12068120</ref> <ref>PMID:12119374</ref> <ref>PMID:12713541</ref> <ref>PMID:17878302</ref> <ref>PMID:17878303</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath~~]]	+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gao~~, Y G~~]]	+	[[Category: Gao YG]]
-	[[Category: Qiao, Z]]	+	[[Category: Qiao Z]]
-	~~[[Category: Enzyme]]~~	+
-	~~[[Category: Plant protein]]~~	+
-	~~[[Category: Synthase~~]]	+

OCA at 10:47, 31 March 2021

2021-03-31T10:47:55Z

←Older revision		Revision as of 10:47, 31 March 2021
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	==Crystal structure of Arabidopsis CESA3 catalytic domain==		==Crystal structure of Arabidopsis CESA3 catalytic domain==
-	<StructureSection load='7ck3' size='340' side='right'caption='[[7ck3]]' scene=''>	+	<StructureSection load='7ck3' size='340' side='right'caption='[[7ck3]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CK3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7ck3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CK3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ck3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ck3 OCA], [https://pdbe.org/7ck3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ck3 RCSB], [https://www.ebi.ac.uk/pdbsum/7ck3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ck3 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CESA3, ATHB, CEV1, ELI1, IXR1, RSW5, At5g05170, K2A11.4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ck3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ck3 OCA], [https://pdbe.org/7ck3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ck3 RCSB], [https://www.ebi.ac.uk/pdbsum/7ck3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ck3 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/CESA3_ARATH CESA3_ARATH]] Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation, especially in roots.<ref>PMID:11340179</ref> <ref>PMID:12068120</ref> <ref>PMID:12119374</ref> <ref>PMID:12713541</ref> <ref>PMID:17878302</ref> <ref>PMID:17878303</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cellulose is synthesized by cellulose synthases (CESAs) from the glycosyltransferase GT-2 family. In plants, the CESAs form a six-lobed rosette-shaped CESA complex (CSC). Here we report crystal structures of the catalytic domain of Arabidopsis thaliana CESA3 (AtCESA3(CatD)) in both apo and uridine diphosphate (UDP)-glucose (UDP-Glc)-bound forms. AtCESA3(CatD) has an overall GT-A fold core domain sandwiched between a plant-conserved region (P-CR) and a class-specific region (C-SR). By superimposing the structure of AtCESA3(CatD) onto the bacterial cellulose synthase BcsA, we found that the coordination of the UDP-Glc differs, indicating different substrate coordination during cellulose synthesis in plants and bacteria. Moreover, structural analyses revealed that AtCESA3(CatD) can form a homodimer mainly via interactions between specific beta strands. We confirmed the importance of specific amino acids on these strands for homodimerization through yeast and in planta assays using point-mutated full-length AtCESA3. Our work provides molecular insights into how the substrate UDP-Glc is coordinated in the CESAs and how the CESAs might dimerize to eventually assemble into CSCs in plants.
		+
		+	Structure of Arabidopsis CESA3 catalytic domain with its substrate UDP-glucose provides insight into the mechanism of cellulose synthesis.,Qiao Z, Lampugnani ER, Yan XF, Khan GA, Saw WG, Hannah P, Qian F, Calabria J, Miao Y, Gruber G, Persson S, Gao YG Proc Natl Acad Sci U S A. 2021 Mar 16;118(11). pii: 2024015118. doi:, 10.1073/pnas.2024015118. PMID:33729990<ref>PMID:33729990</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7ck3" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arath]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gao YG]]	+	[[Category: Gao, Y G]]
-	[[Category: Qiao Z]]	+	[[Category: Qiao, Z]]
		+	[[Category: Enzyme]]
		+	[[Category: Plant protein]]
		+	[[Category: Synthase]]

OCA at 06:46, 17 March 2021

2021-03-17T06:46:20Z

←Older revision		Revision as of 06:46, 17 March 2021
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-	'''Unreleased structure'''

-	~~The entry~~ 7ck3 ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of Arabidopsis CESA3 catalytic domain==
-		+	<StructureSection load='7ck3' size='340' side='right'caption='[[7ck3]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CK3 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ck3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ck3 OCA], [https://pdbe.org/7ck3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ck3 RCSB], [https://www.ebi.ac.uk/pdbsum/7ck3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ck3 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Gao YG]]
		+	[[Category: Qiao Z]]

OCA at 09:40, 29 July 2020

2020-07-29T09:40:47Z

←Older revision		Revision as of 09:40, 29 July 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7ck3 is ON HOLD	+	The entry 7ck3 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7ck3" [edit=sysop:move=sysop]

2020-07-22T08:37:20Z

Protected "7ck3" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:37, 22 July 2020

OCA: New page: '''Unreleased structure''' The entry 7ck3 is ON HOLD Authors: Description: Category: Unreleased Structures

2020-07-22T08:37:19Z

New page: '''Unreleased structure''' The entry 7ck3 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7ck3 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]