7fib - Revision history

OCA at 19:34, 29 May 2024

2024-05-29T19:34:55Z

←Older revision		Revision as of 19:34, 29 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7fib]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FIB FirstGlance]. <br>		<table><tr><td colspan='2'>[[7fib]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FIB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fib OCA], [https://pdbe.org/7fib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fib RCSB], [https://www.ebi.ac.uk/pdbsum/7fib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fib ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fib OCA], [https://pdbe.org/7fib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fib RCSB], [https://www.ebi.ac.uk/pdbsum/7fib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fib ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~A0A2G1TN50_ACIBA A0A2G1TN50_ACIBA]~~]	+	[https://www.uniprot.org/uniprot/ACER_ACIBT ACER_ACIBT] Regulates the expression of the AceI transporter (PubMed:29481596). Binds DNA and chlorhexidine (PubMed:29481596, PubMed:32636271). Binds to regulatory sites within the intergenic region between the aceI and aceR genes, and affects the interaction between RNA polymerase (RNAP) and promoter DNA both in the presence and in the absence of chlorhexidine (PubMed:29481596, PubMed:32636271). In the absence of chlorhexidine, prevents transcription of the aceI gene by disrupting interactions between the promoter DNA and RNAP (PubMed:32636271). In the presence of chlorhexidine, activates expression of aceI (PubMed:29481596, PubMed:32636271). When AceR interacts with chlorhexidine, it undergoes a conformational change and the tetrameric form either releases the DNA or shifts the position of the DNA-binding region to allow RNAP to bind onto the promoter DNA to proceed with aceI transcription (PubMed:32636271).<ref>PMID:29481596</ref> <ref>PMID:32636271</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 03:05, 8 September 2022

2022-09-08T03:05:19Z

←Older revision		Revision as of 03:05, 8 September 2022
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	==Crystal structure of the regulatory domain of AceR in Acinetobacter baumannii==		==Crystal structure of the regulatory domain of AceR in Acinetobacter baumannii==
-	<StructureSection load='7fib' size='340' side='right'caption='[[7fib]]' scene=''>	+	<StructureSection load='7fib' size='340' side='right'caption='[[7fib]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FIB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7fib]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FIB FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fib OCA], [https://pdbe.org/7fib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fib RCSB], [https://www.ebi.ac.uk/pdbsum/7fib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fib ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fib OCA], [https://pdbe.org/7fib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fib RCSB], [https://www.ebi.ac.uk/pdbsum/7fib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fib ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/A0A2G1TN50_ACIBA A0A2G1TN50_ACIBA]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Acinetobacter baumannii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Chi P]]		[[Category: Chi P]]
	[[Category: Guo L]]		[[Category: Guo L]]

OCA at 04:50, 3 August 2022

2022-08-03T04:50:06Z

←Older revision		Revision as of 04:50, 3 August 2022
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-	'''Unreleased structure'''

-	~~The entry 7fib is ON HOLD until Paper Publication~~	+	==Crystal structure of the regulatory domain of AceR in Acinetobacter baumannii==
-		+	<StructureSection load='7fib' size='340' side='right'caption='[[7fib]]' scene=''>
-	~~Authors: Chi, P., Guo, L.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FIB FirstGlance]. <br>
-	~~Description:~~ Crystal structure of the regulatory domain of AceR in Acinetobacter baumannii	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fib OCA], [https://pdbe.org/7fib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fib RCSB], [https://www.ebi.ac.uk/pdbsum/7fib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fib ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Chi, P]]	+	__TOC__
-	[[Category: Guo, L]]	+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Chi P]]
		+	[[Category: Guo L]]

OCA at 11:44, 29 December 2021

2021-12-29T11:44:32Z

←Older revision		Revision as of 11:44, 29 December 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7fib is ON HOLD	+	The entry 7fib is ON HOLD until Paper Publication

	Authors: Chi, P., Guo, L.		Authors: Chi, P., Guo, L.

OCA: Protected "7fib" [edit=sysop:move=sysop]

2021-08-11T04:57:48Z

Protected "7fib" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:57, 11 August 2021

OCA: New page: '''Unreleased structure''' The entry 7fib is ON HOLD Authors: Chi, P., Guo, L. Description: Crystal structure of the regulatory domain of AceR in Acinetobacter baumannii [[Category: Un...

2021-08-11T04:57:47Z

New page: '''Unreleased structure''' The entry 7fib is ON HOLD Authors: Chi, P., Guo, L. Description: Crystal structure of the regulatory domain of AceR in Acinetobacter baumannii [[Category: Un...

New page

'''Unreleased structure'''

The entry 7fib is ON HOLD

Authors: Chi, P., Guo, L.

Description: Crystal structure of the regulatory domain of AceR in Acinetobacter baumannii
[[Category: Unreleased Structures]]
[[Category: Chi, P]]
[[Category: Guo, L]]