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7fpr - Revision history
2026-04-06T12:33:06Z
Revision history for this page on the wiki
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http://52.214.119.220/wiki/index.php?title=7fpr&diff=3873796&oldid=prev
OCA at 14:33, 20 September 2023
2023-09-20T14:33:33Z
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<td colspan='2' style="background-color: white; color:black;">Revision as of 14:33, 20 September 2023</td>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''Unreleased structure'''</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">The entry </del>7fpr is <del style="color: red; font-weight: bold; text-decoration: none;">ON HOLD until Paper Publication</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">==DHFR:NADP+:FOL complex at 290 K (crystal 1)==</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><StructureSection load='</ins>7fpr<ins style="color: red; font-weight: bold; text-decoration: none;">' size='340' side='right'caption='[[7fpr]], [[Resolution|resolution]] 1.07&Aring;' scene=''></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Authors</del>: <del style="color: red; font-weight: bold; text-decoration: none;">Greisman</del>, <del style="color: red; font-weight: bold; text-decoration: none;">J</del>.<del style="color: red; font-weight: bold; text-decoration: none;">B</del>., <del style="color: red; font-weight: bold; text-decoration: none;">Dalton, K</del>.<del style="color: red; font-weight: bold; text-decoration: none;">M</del>., <del style="color: red; font-weight: bold; text-decoration: none;">Brookner</del>, <del style="color: red; font-weight: bold; text-decoration: none;">D</del>.<del style="color: red; font-weight: bold; text-decoration: none;">E</del>., <del style="color: red; font-weight: bold; text-decoration: none;">Hekstra</del>, <del style="color: red; font-weight: bold; text-decoration: none;">D</del>.<del style="color: red; font-weight: bold; text-decoration: none;">R</del>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Structural highlights ==</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><table><tr><td colspan='2'>[[7fpr]] </ins>is <ins style="color: red; font-weight: bold; text-decoration: none;">a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FPR FirstGlance]. <br></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Description</del>: <del style="color: red; font-weight: bold; text-decoration: none;">DHFR</del>:<del style="color: red; font-weight: bold; text-decoration: none;">NADP+:FOL complex at 290 </del>K <del style="color: red; font-weight: bold; text-decoration: none;">(crystal 1)</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.07&#8491;</td></tr></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Unreleased </del>Structures]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands</ins>:<ins style="color: red; font-weight: bold; text-decoration: none;">]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></ins>, <ins style="color: red; font-weight: bold; text-decoration: none;"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Hekstra, D.R</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">org/fgij/fg</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">htm?mol=7fpr FirstGlance]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[http://oca</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">weizmann</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">ac.il/oca-bin/ocaids?id=7fpr OCA]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[https://pdbe.org/7fpr PDBe]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[https://www</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">rcsb</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">org/pdb/explore.do?structureId=7fpr RCSB]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[https://www.ebi.ac.uk/pdbsum/7fpr PDBsum]</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">[https://prosat</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">h-its</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">org/prosat/prosatexe?pdbcode=7fpr ProSAT]</span></td></tr></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Brookner, D.E</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></table></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Greisman<del style="color: red; font-weight: bold; text-decoration: none;">, J.B</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Function ==</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Dalton, K.M</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[https</ins>:<ins style="color: red; font-weight: bold; text-decoration: none;">//www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">__TOC__</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></StructureSection></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category</ins>: <ins style="color: red; font-weight: bold; text-decoration: none;">Escherichia coli </ins>K<ins style="color: red; font-weight: bold; text-decoration: none;">-12]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Large </ins>Structures]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Brookner DE</ins>]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Dalton KM</ins>]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Greisman <ins style="color: red; font-weight: bold; text-decoration: none;">JB</ins>]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Hekstra DR</ins>]]</div></td></tr>
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OCA
http://52.214.119.220/wiki/index.php?title=7fpr&diff=3644328&oldid=prev
OCA at 16:23, 19 October 2022
2022-10-19T16:23:38Z
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<td colspan='2' style="background-color: white; color:black;">Revision as of 16:23, 19 October 2022</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''Unreleased structure'''</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''Unreleased structure'''</div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The entry 7fpr is ON HOLD </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The entry 7fpr is ON HOLD <ins style="color: red; font-weight: bold; text-decoration: none;"> until Paper Publication</ins></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Authors: Greisman, J.B., Dalton, K.M., Brookner, D.E., Hekstra, D.R.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Authors: Greisman, J.B., Dalton, K.M., Brookner, D.E., Hekstra, D.R.</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Description: DHFR:NADP+:FOL complex at 290 K (crystal 1)</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Description: DHFR:NADP+:FOL complex at 290 K (crystal 1)</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Unreleased Structures]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Unreleased Structures]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Greisman, J.B]]</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Dalton, K.M]]</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Hekstra, D.R]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Hekstra, D.R]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Brookner, D.E]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Brookner, D.E]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Greisman, J.B]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Dalton, K.M]]</div></td></tr>
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OCA
http://52.214.119.220/wiki/index.php?title=7fpr&diff=3631664&oldid=prev
OCA: Protected "7fpr" [edit=sysop:move=sysop]
2022-09-21T06:20:40Z
<p>Protected "<a href="/wiki/index.php/7fpr" title="7fpr">7fpr</a>" [edit=sysop:move=sysop]</p>
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 06:20, 21 September 2022</td>
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OCA
http://52.214.119.220/wiki/index.php?title=7fpr&diff=3631663&oldid=prev
OCA: New page: '''Unreleased structure''' The entry 7fpr is ON HOLD Authors: Greisman, J.B., Dalton, K.M., Brookner, D.E., Hekstra, D.R. Description: DHFR:NADP+:FOL complex at 290 K (crystal 1) [[Cat...
2022-09-21T06:20:39Z
<p>New page: '''Unreleased structure''' The entry 7fpr is ON HOLD Authors: Greisman, J.B., Dalton, K.M., Brookner, D.E., Hekstra, D.R. Description: DHFR:NADP+:FOL complex at 290 K (crystal 1) [[Cat...</p>
<p><b>New page</b></p><div>'''Unreleased structure'''<br />
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The entry 7fpr is ON HOLD <br />
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Authors: Greisman, J.B., Dalton, K.M., Brookner, D.E., Hekstra, D.R.<br />
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Description: DHFR:NADP+:FOL complex at 290 K (crystal 1)<br />
[[Category: Unreleased Structures]]<br />
[[Category: Greisman, J.B]]<br />
[[Category: Dalton, K.M]]<br />
[[Category: Hekstra, D.R]]<br />
[[Category: Brookner, D.E]]</div>
OCA