7kmb - Revision history

OCA at 07:49, 1 May 2024

2024-05-01T07:49:25Z

←Older revision		Revision as of 07:49, 1 May 2024
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-	====	+	==ACE2-RBD Focused Refinement Using Symmetry Expansion of Applied C3 for Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 7.4==
-	<StructureSection load='7kmb' size='340' side='right'caption='[[7kmb]]' scene=''>	+	<StructureSection load='7kmb' size='340' side='right'caption='[[7kmb]], [[Resolution\|resolution]] 3.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7kmb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KMB FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kmb OCA], [https://pdbe.org/7kmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kmb RCSB], [https://www.ebi.ac.uk/pdbsum/7kmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kmb ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.39Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kmb OCA], [https://pdbe.org/7kmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kmb RCSB], [https://www.ebi.ac.uk/pdbsum/7kmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kmb ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ACE2_HUMAN ACE2_HUMAN] Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.<ref>PMID:10969042</ref> <ref>PMID:10924499</ref> <ref>PMID:14647384</ref>
		+
		+	==See Also==
		+	*[[Angiotensin-Converting Enzyme 3D structures\|Angiotensin-Converting Enzyme 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Severe acute respiratory syndrome coronavirus 2]]
		+	[[Category: Gorman J]]
		+	[[Category: Kwong PD]]
		+	[[Category: Shapiro L]]

OCA at 16:57, 15 December 2021

2021-12-15T16:57:06Z

←Older revision		Revision as of 16:57, 15 December 2021
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	<StructureSection load='7kmb' size='340' side='right'caption='[[7kmb]]' scene=''>		<StructureSection load='7kmb' size='340' side='right'caption='[[7kmb]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7kmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kmb OCA], [~~http~~://pdbe.org/7kmb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7kmb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7kmb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7kmb ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kmb OCA], [https://pdbe.org/7kmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kmb RCSB], [https://www.ebi.ac.uk/pdbsum/7kmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kmb ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 06:42, 9 December 2020

2020-12-09T06:42:30Z

←Older revision		Revision as of 06:42, 9 December 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 7kmb ~~is ON HOLD~~	+	====
-		+	<StructureSection load='7kmb' size='340' side='right'caption='[[7kmb]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7kmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kmb OCA], [http://pdbe.org/7kmb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7kmb RCSB], [http://www.ebi.ac.uk/pdbsum/7kmb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7kmb ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA: Protected "7kmb" [edit=sysop:move=sysop]

2020-11-11T06:34:14Z

Protected "7kmb" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:34, 11 November 2020

OCA: New page: '''Unreleased structure''' The entry 7kmb is ON HOLD Authors: Description: Category: Unreleased Structures

2020-11-11T06:34:13Z

New page: '''Unreleased structure''' The entry 7kmb is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7kmb is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]