7lve - Revision history

OCA at 11:16, 14 June 2023

2023-06-14T11:16:00Z

←Older revision		Revision as of 11:16, 14 June 2023
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	==Jug r 2 Leader Sequence Residues 117-161==		==Jug r 2 Leader Sequence Residues 117-161==
-	<StructureSection load='7lve' size='340' side='right'caption='[[7lve~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='7lve' size='340' side='right'caption='[[7lve]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7lve]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LVE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7lve]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Juglans_regia Juglans regia]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LVE FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lve OCA], [https://pdbe.org/7lve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lve RCSB], [https://www.ebi.ac.uk/pdbsum/7lve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lve ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lve OCA], [https://pdbe.org/7lve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lve RCSB], [https://www.ebi.ac.uk/pdbsum/7lve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lve ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/VCL2_JUGRE VCL2_JUGRE]] Seed storage protein.<ref>PMID:10589017</ref> <ref>PMID:21883278</ref> <ref>PMID:25388987</ref> <ref>PMID:30054513</ref>	+	[https://www.uniprot.org/uniprot/VCL2_JUGRE VCL2_JUGRE] Seed storage protein.<ref>PMID:10589017</ref> <ref>PMID:21883278</ref> <ref>PMID:25388987</ref> <ref>PMID:30054513</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Juglans regia]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: DeRose~~, E F~~]]	+	[[Category: DeRose EF]]
-	[[Category: Foo~~, A C.Y~~]]	+	[[Category: Foo ACY]]
-	[[Category: Mueller~~, G A]]~~	+	[[Category: Mueller GA]]
-	~~[[Category: Allergen]]~~	+
-	~~[[Category: Seed storage~~]]	+

OCA at 08:40, 23 February 2022

2022-02-23T08:40:22Z

←Older revision		Revision as of 08:40, 23 February 2022
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	==Jug r 2 Leader Sequence Residues 117-161==		==Jug r 2 Leader Sequence Residues 117-161==
-	<StructureSection load='7lve' size='340' side='right'caption='[[7lve]]' scene=''>	+	<StructureSection load='7lve' size='340' side='right'caption='[[7lve]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LVE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7lve]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LVE FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lve OCA], [https://pdbe.org/7lve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lve RCSB], [https://www.ebi.ac.uk/pdbsum/7lve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lve ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lve OCA], [https://pdbe.org/7lve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lve RCSB], [https://www.ebi.ac.uk/pdbsum/7lve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lve ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/VCL2_JUGRE VCL2_JUGRE]] Seed storage protein.<ref>PMID:10589017</ref> <ref>PMID:21883278</ref> <ref>PMID:25388987</ref> <ref>PMID:30054513</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Vicilin-buried peptides (VBPs) from edible plants are derived from the N-terminal leader sequences (LSs) of seed storage proteins. VBPs are defined by a common alpha-hairpin fold mediated by conserved CxxxCx(10-14)CxxxC motifs. Here, peanut and walnut VBPs were characterized as potential mediators of both peanut/walnut allergenicity and cross-reactivity despite their low ( approximately 17%) sequence identity. The structures of one peanut (AH1.1) and 3 walnut (JR2.1, JR2.2, JR2.3) VBPs were solved using solution NMR, revealing similar alpha-hairpin structures stabilized by disulfide bonds with high levels of surface similarity. Peptide microarrays identified several peptide sequences primarily on AH1.1 and JR2.1, which were recognized by peanut-, walnut-, and dual-allergic patient IgE, establishing these peanut and walnut VBPs as potential mediators of allergenicity and cross-reactivity. JR2.2 and JR2.3 displayed extreme resilience against endosomal digestion, potentially hindering epitope generation and likely contributing to their reduced allergic potential.
		+
		+	Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides.,Foo ACY, Nesbit JB, Gipson SAY, Cheng H, Bushel P, DeRose EF, Schein CH, Teuber SS, Hurlburt BK, Maleki SJ, Mueller GA J Agric Food Chem. 2022 Feb 9. doi: 10.1021/acs.jafc.1c07225. PMID:35139305<ref>PMID:35139305</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7lve" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: DeRose EF]]	+	[[Category: DeRose, E F]]
-	[[Category: Foo ~~ACY~~]]	+	[[Category: Foo, A C.Y]]
-	[[Category: Mueller GA]]	+	[[Category: Mueller, G A]]
		+	[[Category: Allergen]]
		+	[[Category: Seed storage]]

OCA at 06:59, 2 February 2022

2022-02-02T06:59:18Z

←Older revision		Revision as of 06:59, 2 February 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7lve is ~~ON HOLD until Paper Publication~~	+	==Jug r 2 Leader Sequence Residues 117-161==
-		+	<StructureSection load='7lve' size='340' side='right'caption='[[7lve]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LVE FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lve OCA], [https://pdbe.org/7lve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lve RCSB], [https://www.ebi.ac.uk/pdbsum/7lve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lve ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: DeRose EF]]
		+	[[Category: Foo ACY]]
		+	[[Category: Mueller GA]]

OCA at 14:44, 10 March 2021

2021-03-10T14:44:27Z

←Older revision		Revision as of 14:44, 10 March 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7lve is ON HOLD	+	The entry 7lve is ON HOLD until Paper Publication

-	Authors: ~~Mueller, G.A., Foo, A.C.Y., DeRose, E.F.~~	+	Authors:

-	Description: ~~Jug R 2 N-Terminal Fragment 3~~	+	Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Mueller, G.A]]
-	[[Category: Derose, E.F]]
-	[[Category: Foo, A.C.Y]]

OCA: Protected "7lve" [edit=sysop:move=sysop]

2021-03-03T13:29:11Z

Protected "7lve" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:29, 3 March 2021

OCA: New page: '''Unreleased structure''' The entry 7lve is ON HOLD Authors: Mueller, G.A., Foo, A.C.Y., DeRose, E.F. Description: Jug R 2 N-Terminal Fragment 3 Category: Unreleased Structures [[...

2021-03-03T13:29:10Z

New page: '''Unreleased structure''' The entry 7lve is ON HOLD Authors: Mueller, G.A., Foo, A.C.Y., DeRose, E.F. Description: Jug R 2 N-Terminal Fragment 3 Category: Unreleased Structures [[...

New page

'''Unreleased structure'''

The entry 7lve is ON HOLD

Authors: Mueller, G.A., Foo, A.C.Y., DeRose, E.F.

Description: Jug R 2 N-Terminal Fragment 3
[[Category: Unreleased Structures]]
[[Category: Mueller, G.A]]
[[Category: Derose, E.F]]
[[Category: Foo, A.C.Y]]