7p2z - Revision history

OCA at 13:00, 1 February 2024

2024-02-01T13:00:41Z

←Older revision		Revision as of 13:00, 1 February 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7p2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[7p2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YTW:(3~{a}~{R},4~{S},5~{S},6~{S},7~{R},7~{a}~{S})-7-(hydroxymethyl)-2,2-bis(oxidanylidene)-3~{a},4,5,6,7,7~{a}-hexahydro-3~{H}-benzo[d][1,2,3]oxathiazole-4,5,6-triol'>YTW</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YTW:(3~{a}~{R},4~{S},5~{S},6~{S},7~{R},7~{a}~{S})-7-(hydroxymethyl)-2,2-bis(oxidanylidene)-3~{a},4,5,6,7,7~{a}-hexahydro-3~{H}-benzo[d][1,2,3]oxathiazole-4,5,6-triol'>YTW</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2z OCA], [https://pdbe.org/7p2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2z RCSB], [https://www.ebi.ac.uk/pdbsum/7p2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2z OCA], [https://pdbe.org/7p2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2z RCSB], [https://www.ebi.ac.uk/pdbsum/7p2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2z ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN]] Glycogen storage disease due to acid maltase deficiency, infantile onset;Glycogen storage disease due to acid maltase deficiency, juvenile onset;Glycogen storage disease due to acid maltase deficiency, adult onset. The disease is caused by mutations affecting the gene represented in this entry.	+	[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN] Glycogen storage disease due to acid maltase deficiency, infantile onset;Glycogen storage disease due to acid maltase deficiency, juvenile onset;Glycogen storage disease due to acid maltase deficiency, adult onset. The disease is caused by mutations affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN]] Essential for the degradation of glygogen to glucose in lysosomes.	+	[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN] Essential for the degradation of glygogen to glucose in lysosomes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 19:46, 7 September 2022

2022-09-07T19:46:03Z

←Older revision		Revision as of 19:46, 7 September 2022
Line 3:		Line 3:
	<StructureSection load='7p2z' size='340' side='right'caption='[[7p2z]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='7p2z' size='340' side='right'caption='[[7p2z]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7p2z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7p2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YTW:(3~{a}~{R},4~{S},5~{S},6~{S},7~{R},7~{a}~{S})-7-(hydroxymethyl)-2,2-bis(oxidanylidene)-3~{a},4,5,6,7,7~{a}-hexahydro-3~{H}-benzo[d][1,2,3]oxathiazole-4,5,6-triol'>YTW</scene~~>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YTW:(3~{a}~{R},4~{S},5~{S},6~{S},7~{R},7~{a}~{S})-7-(hydroxymethyl)-2,2-bis(oxidanylidene)-3~{a},4,5,6,7,7~{a}-hexahydro-3~{H}-benzo[d][1,2,3]oxathiazole-4,5,6-triol'>YTW</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2z OCA], [https://pdbe.org/7p2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2z RCSB], [https://www.ebi.ac.uk/pdbsum/7p2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2z OCA], [https://pdbe.org/7p2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2z RCSB], [https://www.ebi.ac.uk/pdbsum/7p2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2z ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN]] Glycogen storage disease due to acid maltase deficiency, infantile onset;Glycogen storage disease due to acid maltase deficiency, juvenile onset;Glycogen storage disease due to acid maltase deficiency, adult onset. The disease is caused by mutations affecting the gene represented in this entry.	+	[[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN]] Glycogen storage disease due to acid maltase deficiency, infantile onset;Glycogen storage disease due to acid maltase deficiency, juvenile onset;Glycogen storage disease due to acid maltase deficiency, adult onset. The disease is caused by mutations affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN]] Essential for the degradation of glygogen to glucose in lysosomes.	+	[[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN]] Essential for the degradation of glygogen to glucose in lysosomes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 7p2z" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 7p2z" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Alpha-glucosidase 3D structures\|Alpha-glucosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Alpha-glucosidase~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Artola, M]]	+	[[Category: Artola M]]
-	[[Category: Kok, K]]	+	[[Category: Kok K]]
-	[[Category: Overkleeft, H]]	+	[[Category: Overkleeft H]]
-	[[Category: Roig-Zamboni, V]]	+	[[Category: Roig-Zamboni V]]
-	[[Category: Sulzenbacher, G]]	+	[[Category: Sulzenbacher G]]
-	~~[[Category: Alpha-glycosidase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Lysosomal]]~~	+
-	~~[[Category: Pharmacological chaperone]]~~	+
-	~~[[Category: Pompe disease~~]]	+

OCA at 06:43, 31 August 2022

2022-08-31T06:43:03Z

←Older revision		Revision as of 06:43, 31 August 2022
Line 1:		Line 1:

	==Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with cyclosulfamidate 4==		==Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with cyclosulfamidate 4==
-	<StructureSection load='7p2z' size='340' side='right'caption='[[7p2z]]' scene=''>	+	<StructureSection load='7p2z' size='340' side='right'caption='[[7p2z]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7p2z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2Z FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2z OCA], [https://pdbe.org/7p2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2z RCSB], [https://www.ebi.ac.uk/pdbsum/7p2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2z ProSAT]</span></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YTW:(3~{a}~{R},4~{S},5~{S},6~{S},7~{R},7~{a}~{S})-7-(hydroxymethyl)-2,2-bis(oxidanylidene)-3~{a},4,5,6,7,7~{a}-hexahydro-3~{H}-benzo[d][1,2,3]oxathiazole-4,5,6-triol'>YTW</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2z OCA], [https://pdbe.org/7p2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2z RCSB], [https://www.ebi.ac.uk/pdbsum/7p2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2z ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN]] Glycogen storage disease due to acid maltase deficiency, infantile onset;Glycogen storage disease due to acid maltase deficiency, juvenile onset;Glycogen storage disease due to acid maltase deficiency, adult onset. The disease is caused by mutations affecting the gene represented in this entry.
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/LYAG_HUMAN LYAG_HUMAN]] Essential for the degradation of glygogen to glucose in lysosomes.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	alpha-Glucosidase inhibitors are potential therapeutics for the treatment of diabetes, viral infections, and Pompe disease. Herein, we report a 1,6-epi-cyclophellitol cyclosulfamidate as a new class of reversible alpha-glucosidase inhibitors that displays enzyme inhibitory activity by virtue of its conformational mimicry of the substrate when bound in the Michaelis complex. The alpha-d-glc-configured cyclophellitol cyclosulfamidate 4 binds in a competitive manner the human lysosomal acid alpha-glucosidase (GAA), ER alpha-glucosidases, and, at higher concentrations, intestinal alpha-glucosidases, displaying an excellent selectivity over the human beta-glucosidases GBA and GBA2 and glucosylceramide synthase (GCS). Cyclosulfamidate 4 stabilizes recombinant human GAA (rhGAA, alglucosidase alfa, Myozyme) in cell medium and plasma and facilitates enzyme trafficking to lysosomes. It stabilizes rhGAA more effectively than existing small-molecule chaperones and does so in vitro, in cellulo, and in vivo in zebrafish, thus representing a promising therapeutic alternative to Miglustat for Pompe disease.
		+
		+	1,6-epi-Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal alpha-Glucosidase Stabilizer for the Treatment of Pompe Disease.,Kok K, Kuo CL, Katzy RE, Lelieveld LT, Wu L, Roig-Zamboni V, van der Marel GA, Codee JDC, Sulzenbacher G, Davies GJ, Overkleeft HS, Aerts JMFG, Artola M J Am Chem Soc. 2022 Aug 17;144(32):14819-14827. doi: 10.1021/jacs.2c05666. Epub, 2022 Aug 2. PMID:35917590<ref>PMID:35917590</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7p2z" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Alpha-glucosidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Artola M]]	+	[[Category: Artola, M]]
-	[[Category: Kok K]]	+	[[Category: Kok, K]]
-	[[Category: Overkleeft H]]	+	[[Category: Overkleeft, H]]
-	[[Category: Roig-Zamboni V]]	+	[[Category: Roig-Zamboni, V]]
-	[[Category: Sulzenbacher G]]	+	[[Category: Sulzenbacher, G]]
		+	[[Category: Alpha-glycosidase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Lysosomal]]
		+	[[Category: Pharmacological chaperone]]
		+	[[Category: Pompe disease]]

OCA at 05:14, 13 July 2022

2022-07-13T05:14:42Z

←Older revision		Revision as of 05:14, 13 July 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 7p2z is ON HOLD until 2023-07-06~~	+	==Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with cyclosulfamidate 4==
-		+	<StructureSection load='7p2z' size='340' side='right'caption='[[7p2z]]' scene=''>
-	~~Authors: Roig-Zamboni, V., Kok, K., Overkleeft, H., Artola, M., Sulzenbacher, G.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2Z FirstGlance]. <br>
-	~~Description:~~ Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with cyclosulfamidate 4	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2z OCA], [https://pdbe.org/7p2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2z RCSB], [https://www.ebi.ac.uk/pdbsum/7p2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2z ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Kok~~, K]]	+	__TOC__
-	[[Category: ~~Roig-Zamboni, V~~]]	+	</StructureSection>
-	[[Category: Artola, M]]	+	[[Category: Large Structures]]
-	[[Category: Overkleeft, H]]	+	[[Category: Artola M]]
-	[[Category: Sulzenbacher, G]]	+	[[Category: Kok K]]
		+	[[Category: Overkleeft H]]
		+	[[Category: Roig-Zamboni V]]
		+	[[Category: Sulzenbacher G]]

OCA at 06:25, 22 June 2022

2022-06-22T06:25:22Z

←Older revision		Revision as of 06:25, 22 June 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7p2z is ON HOLD until ~~Jul 06~~ 2023	+	The entry 7p2z is ON HOLD until 2023-07-06

	Authors: Roig-Zamboni, V., Kok, K., Overkleeft, H., Artola, M., Sulzenbacher, G.		Authors: Roig-Zamboni, V., Kok, K., Overkleeft, H., Artola, M., Sulzenbacher, G.
Line 7:		Line 7:
	Description: Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with cyclosulfamidate 4		Description: Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with cyclosulfamidate 4
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Kok, K]]
		+	[[Category: Roig-Zamboni, V]]
	[[Category: Artola, M]]		[[Category: Artola, M]]
	[[Category: Overkleeft, H]]		[[Category: Overkleeft, H]]
-	[[Category: Kok, K]]
	[[Category: Sulzenbacher, G]]		[[Category: Sulzenbacher, G]]
-	[[Category: Roig-Zamboni, V]]

OCA at 08:57, 18 May 2022

2022-05-18T08:57:51Z

←Older revision		Revision as of 08:57, 18 May 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7p2z is ON HOLD	+	The entry 7p2z is ON HOLD until Jul 06 2023

	Authors: Roig-Zamboni, V., Kok, K., Overkleeft, H., Artola, M., Sulzenbacher, G.		Authors: Roig-Zamboni, V., Kok, K., Overkleeft, H., Artola, M., Sulzenbacher, G.
Line 7:		Line 7:
	Description: Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with cyclosulfamidate 4		Description: Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with cyclosulfamidate 4
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Kok~~, K]]	+	[[Category: Artola, M]]
	[[Category: Overkleeft, H]]		[[Category: Overkleeft, H]]
		+	[[Category: Kok, K]]
	[[Category: Sulzenbacher, G]]		[[Category: Sulzenbacher, G]]
	[[Category: Roig-Zamboni, V]]		[[Category: Roig-Zamboni, V]]
-	[[Category: Artola, M]]

OCA: Protected "7p2z" [edit=sysop:move=sysop]

2021-07-14T08:52:37Z

Protected "7p2z" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:52, 14 July 2021

OCA: New page: '''Unreleased structure''' The entry 7p2z is ON HOLD Authors: Roig-Zamboni, V., Kok, K., Overkleeft, H., Artola, M., Sulzenbacher, G. Description: Crystal structure of human lysosomal ...

2021-07-14T08:52:36Z

New page: '''Unreleased structure''' The entry 7p2z is ON HOLD Authors: Roig-Zamboni, V., Kok, K., Overkleeft, H., Artola, M., Sulzenbacher, G. Description: Crystal structure of human lysosomal ...

New page

'''Unreleased structure'''

The entry 7p2z is ON HOLD

Authors: Roig-Zamboni, V., Kok, K., Overkleeft, H., Artola, M., Sulzenbacher, G.

Description: Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with cyclosulfamidate 4
[[Category: Unreleased Structures]]
[[Category: Kok, K]]
[[Category: Overkleeft, H]]
[[Category: Sulzenbacher, G]]
[[Category: Roig-Zamboni, V]]
[[Category: Artola, M]]