7ve2 - Revision history

OCA at 17:23, 29 November 2023

2023-11-29T17:23:25Z

←Older revision		Revision as of 17:23, 29 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7ve2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VE2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7ve2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VE2 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene>, <scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene>, <scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ve2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ve2 OCA], [https://pdbe.org/7ve2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ve2 RCSB], [https://www.ebi.ac.uk/pdbsum/7ve2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ve2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ve2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ve2 OCA], [https://pdbe.org/7ve2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ve2 RCSB], [https://www.ebi.ac.uk/pdbsum/7ve2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ve2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/PLM2_PLAF7 PLM2_PLAF7] During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation (PubMed:29943906). May cleave preferentially denatured hemoglobin that has been cleaved by PMI (By similarity). Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).[UniProtKB:P46925]<ref>PMID:29943906</ref>		[https://www.uniprot.org/uniprot/PLM2_PLAF7 PLM2_PLAF7] During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation (PubMed:29943906). May cleave preferentially denatured hemoglobin that has been cleaved by PMI (By similarity). Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).[UniProtKB:P46925]<ref>PMID:29943906</ref>
		+
		+	==See Also==
		+	*[[Plasmepsin\|Plasmepsin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:16, 1 February 2023

2023-02-01T11:16:32Z

←Older revision		Revision as of 11:16, 1 February 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7ve2 is ~~ON HOLD until 2024~~-03-07	+	==Crystal Structure of Lopinavir bound Plasmepsin II (PMII) from Plasmodium falciparum==
-		+	<StructureSection load='7ve2' size='340' side='right'caption='[[7ve2]], [[Resolution\|resolution]] 3.20Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7ve2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VE2 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene>, <scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ve2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ve2 OCA], [https://pdbe.org/7ve2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ve2 RCSB], [https://www.ebi.ac.uk/pdbsum/7ve2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ve2 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PLM2_PLAF7 PLM2_PLAF7] During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation (PubMed:29943906). May cleave preferentially denatured hemoglobin that has been cleaved by PMI (By similarity). Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).[UniProtKB:P46925]<ref>PMID:29943906</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Plasmodium falciparum 3D7]]
		+	[[Category: Bhaumik P]]
		+	[[Category: Mishra V]]
		+	[[Category: Rathore I]]

OCA at 05:16, 31 August 2022

2022-08-31T05:16:40Z

←Older revision		Revision as of 05:16, 31 August 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7ve2 is ON HOLD until ~~Paper Publication~~	+	The entry 7ve2 is ON HOLD until 2024-03-07

	Authors:		Authors:

OCA at 10:31, 13 October 2021

2021-10-13T10:31:01Z

←Older revision		Revision as of 10:31, 13 October 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7ve2 is ON HOLD	+	The entry 7ve2 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7ve2" [edit=sysop:move=sysop]

2021-09-15T08:28:09Z

Protected "7ve2" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:28, 15 September 2021

OCA: New page: '''Unreleased structure''' The entry 7ve2 is ON HOLD Authors: Description: Category: Unreleased Structures

2021-09-15T08:28:08Z

New page: '''Unreleased structure''' The entry 7ve2 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7ve2 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]