7w6p - Revision history

OCA at 06:18, 28 September 2022

2022-09-28T06:18:32Z

←Older revision		Revision as of 06:18, 28 September 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7w6p is ~~ON HOLD until Paper Publication~~	+	==Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist==
-		+	<StructureSection load='7w6p' size='340' side='right'caption='[[7w6p]], [[Resolution\|resolution]] 3.47Å' scene=''>
-	~~Authors~~: Xu, J., ~~Fink~~, E.A., ~~Shoichet, B~~.K., ~~Du, Y~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7w6p]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7W6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7W6P FirstGlance]. <br>
-	~~Description~~: ~~Cryo-EM structure of~~ the ~~alpha2A adrenergic receptor GoA~~ signaling ~~complex bound to a~~ G protein ~~biased agonist~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=W96:N-pyridin-4-ylisoquinolin-4-amine'>W96</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7w6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7w6p OCA], [https://pdbe.org/7w6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7w6p RCSB], [https://www.ebi.ac.uk/pdbsum/7w6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7w6p ProSAT]</span></td></tr>
-	[[Category: ~~Fink, E.A~~]]	+	</table>
-	[[Category: ~~Xu, J~~]]	+	== Disease ==
-	[[Category: Du, Y]]	+	[[https://www.uniprot.org/uniprot/GNAO_HUMAN GNAO_HUMAN]] Early infantile epileptic encephalopathy. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
-	[[Category: Shoichet~~, B.K~~]]	+	== Function ==
		+	[[https://www.uniprot.org/uniprot/GNAO_HUMAN GNAO_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Mus musculus]]
		+	[[Category: Du Y]]
		+	[[Category: Fink EA]]
		+	[[Category: Shoichet BK]]
		+	[[Category: Xu J]]

OCA at 15:18, 7 September 2022

2022-09-07T15:18:06Z

←Older revision		Revision as of 15:18, 7 September 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7w6p is ON HOLD	+	The entry 7w6p is ON HOLD until Paper Publication

	Authors: Xu, J., Fink, E.A., Shoichet, B.K., Du, Y.		Authors: Xu, J., Fink, E.A., Shoichet, B.K., Du, Y.
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	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Fink, E.A]]		[[Category: Fink, E.A]]
-	[[Category: Du, Y]]
	[[Category: Xu, J]]		[[Category: Xu, J]]
		+	[[Category: Du, Y]]
	[[Category: Shoichet, B.K]]		[[Category: Shoichet, B.K]]

OCA at 03:25, 18 August 2022

2022-08-18T03:25:03Z

←Older revision		Revision as of 03:25, 18 August 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7w6p is ON HOLD ~~until Paper Publication~~	+	The entry 7w6p is ON HOLD

	Authors: Xu, J., Fink, E.A., Shoichet, B.K., Du, Y.		Authors: Xu, J., Fink, E.A., Shoichet, B.K., Du, Y.
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	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Fink, E.A]]		[[Category: Fink, E.A]]
-	[[Category: Xu, J]]
	[[Category: Du, Y]]		[[Category: Du, Y]]
		+	[[Category: Xu, J]]
	[[Category: Shoichet, B.K]]		[[Category: Shoichet, B.K]]

OCA at 09:23, 5 January 2022

2022-01-05T09:23:52Z

←Older revision		Revision as of 09:23, 5 January 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7w6p is ON HOLD	+	The entry 7w6p is ON HOLD until Paper Publication

	Authors: Xu, J., Fink, E.A., Shoichet, B.K., Du, Y.		Authors: Xu, J., Fink, E.A., Shoichet, B.K., Du, Y.

OCA: Protected "7w6p" [edit=sysop:move=sysop]

2021-12-08T08:48:05Z

Protected "7w6p" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:48, 8 December 2021

OCA: New page: '''Unreleased structure''' The entry 7w6p is ON HOLD Authors: Xu, J., Fink, E.A., Shoichet, B.K., Du, Y. Description: Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling...

2021-12-08T08:48:04Z

New page: '''Unreleased structure''' The entry 7w6p is ON HOLD Authors: Xu, J., Fink, E.A., Shoichet, B.K., Du, Y. Description: Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling...

New page

'''Unreleased structure'''

The entry 7w6p is ON HOLD

Authors: Xu, J., Fink, E.A., Shoichet, B.K., Du, Y.

Description: Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist
[[Category: Unreleased Structures]]
[[Category: Fink, E.A]]
[[Category: Xu, J]]
[[Category: Du, Y]]
[[Category: Shoichet, B.K]]