7win - Revision history

OCA at 17:41, 29 November 2023

2023-11-29T17:41:08Z

←Older revision		Revision as of 17:41, 29 November 2023
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	<StructureSection load='7win' size='340' side='right'caption='[[7win]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='7win' size='340' side='right'caption='[[7win]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[7win]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WIN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7win]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WIN FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7win FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7win OCA], [https://pdbe.org/7win PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7win RCSB], [https://www.ebi.ac.uk/pdbsum/7win PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7win ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.95Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7win FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7win OCA], [https://pdbe.org/7win PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7win RCSB], [https://www.ebi.ac.uk/pdbsum/7win PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7win ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.	+	[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 7win" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 7win" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Bromodomain adjacent to zinc finger 3D structures\|Bromodomain adjacent to zinc finger 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Feng~~, Y Y~~]]	+	[[Category: Feng YY]]
-	[[Category: Liu, K]]	+	[[Category: Liu K]]
-	[[Category: Min~~, J R]]~~	+	[[Category: Min JR]]
-	~~[[Category: Baz2b]]~~	+
-	~~[[Category: Dna binding protein]]~~	+
-	~~[[Category: Tam domain~~]]	+

OCA at 06:44, 18 August 2022

2022-08-18T06:44:54Z

←Older revision		Revision as of 06:44, 18 August 2022
Line 1:		Line 1:

	==Crystal structure of BAZ2B TAM domain==		==Crystal structure of BAZ2B TAM domain==
-	<StructureSection load='7win' size='340' side='right'caption='[[7win]]' scene=''>	+	<StructureSection load='7win' size='340' side='right'caption='[[7win]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WIN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7win]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WIN FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7win FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7win OCA], [https://pdbe.org/7win PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7win RCSB], [https://www.ebi.ac.uk/pdbsum/7win PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7win ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7win FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7win OCA], [https://pdbe.org/7win PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7win RCSB], [https://www.ebi.ac.uk/pdbsum/7win PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7win ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	BAZ2B is a regulatory subunit of the ISWI (Imitation Switch) remodeling complex and engages in nucleosome remodeling. Loss-of-function and haploinsufficiency of BAZ2B are associated with different diseases. BAZ2B is a large multidomain protein. In addition to the epigenetic reader domains plant homeodomain (PHD) and bromodomain (BRD), BAZ2B also has a Tip5/ARBP/MBD (TAM) domain. Sequence alignment revealed that the TAM domains of BAZ2A and BAZ2B share 53% sequence identity. How the BAZ2A TAM domain bound with DNA has been characterized recently, however, the DNA binding ability and methylation preference, as well as the structural basis of the BAZ2B TAM domain are not studied yet. In this study, we measured the DNA binding affinity of the TAM domain of BAZ2B, and also determined its apo crystal structure. We found that the TAM domains of BAZ2A and BAZ2B adopt almost the same fold, and like BAZ2A, the BAZ2B TAM domain also binds to dsDNA without methyl-cytosine preference, implying that the BAZ2B TAM domain might recognize DNA in a similar binding mode to that of the BAZ2A TAM domain. These results provide clues for the biological function study of BAZ2B in the future.
		+
		+	Crystal structure of the BAZ2B TAM domain.,Feng Y, Chen S, Zhou M, Zhang J, Min J, Liu K Heliyon. 2022 Jul 6;8(7):e09873. doi: 10.1016/j.heliyon.2022.e09873. eCollection , 2022 Jul. PMID:35865993<ref>PMID:35865993</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7win" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Feng YY]]	+	[[Category: Feng, Y Y]]
-	[[Category: Liu K]]	+	[[Category: Liu, K]]
-	[[Category: Min JR]]	+	[[Category: Min, J R]]
		+	[[Category: Baz2b]]
		+	[[Category: Dna binding protein]]
		+	[[Category: Tam domain]]

OCA at 07:05, 2 February 2022

2022-02-02T07:05:31Z

←Older revision		Revision as of 07:05, 2 February 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7win ~~is ON HOLD~~	+	==Crystal structure of BAZ2B TAM domain==
-		+	<StructureSection load='7win' size='340' side='right'caption='[[7win]]' scene=''>
-	~~Authors~~: ~~Feng~~, Y.Y., ~~Liu~~, K., ~~Min~~, J.R.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WIN FirstGlance]. <br>
-	~~Description: Crystal structure of BAZ2B TAM domain~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7win FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7win OCA], [https://pdbe.org/7win PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7win RCSB], [https://www.ebi.ac.uk/pdbsum/7win PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7win ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Feng~~, Y.Y~~]]	+	__TOC__
-	[[Category: ~~Min, J.R~~]]	+	</StructureSection>
-	[[Category: ~~Liu, K~~]]	+	[[Category: Large Structures]]
		+	[[Category: Feng YY]]
		+	[[Category: Liu K]]
		+	[[Category: Min JR]]

OCA: Protected "7win" [edit=sysop:move=sysop]

2022-01-12T08:46:28Z

Protected "7win" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:46, 12 January 2022

OCA: New page: '''Unreleased structure''' The entry 7win is ON HOLD Authors: Feng, Y.Y., Liu, K., Min, J.R. Description: Crystal structure of BAZ2B TAM domain Category: Unreleased Structures [[Ca...

2022-01-12T08:46:27Z

New page: '''Unreleased structure''' The entry 7win is ON HOLD Authors: Feng, Y.Y., Liu, K., Min, J.R. Description: Crystal structure of BAZ2B TAM domain Category: Unreleased Structures [[Ca...

New page

'''Unreleased structure'''

The entry 7win is ON HOLD

Authors: Feng, Y.Y., Liu, K., Min, J.R.

Description: Crystal structure of BAZ2B TAM domain
[[Category: Unreleased Structures]]
[[Category: Feng, Y.Y]]
[[Category: Min, J.R]]
[[Category: Liu, K]]