7xf5 - Revision history

OCA at 11:19, 15 November 2023

2023-11-15T11:19:54Z

←Older revision		Revision as of 11:19, 15 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7xf5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XF5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7xf5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XF5 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xf5 OCA], [https://pdbe.org/7xf5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xf5 RCSB], [https://www.ebi.ac.uk/pdbsum/7xf5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xf5 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.9Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xf5 OCA], [https://pdbe.org/7xf5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xf5 RCSB], [https://www.ebi.ac.uk/pdbsum/7xf5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xf5 ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==

OCA at 07:25, 3 May 2023

2023-05-03T07:25:17Z

←Older revision		Revision as of 07:25, 3 May 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7xf5 is ~~ON HOLD until 2024~~-05-03	+	==Full length human CLC-2 channel in apo state==
-		+	<StructureSection load='7xf5' size='340' side='right'caption='[[7xf5]], [[Resolution\|resolution]] 3.90Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7xf5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XF5 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xf5 OCA], [https://pdbe.org/7xf5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xf5 RCSB], [https://www.ebi.ac.uk/pdbsum/7xf5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xf5 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/CLCN2_HUMAN CLCN2_HUMAN] Leukoencephalopathy with mild cerebellar ataxia and white matter edema;Familial hyperaldosteronism type II;Juvenile myoclonic epilepsy. Disease susceptibility is associated with variants affecting the gene represented in this entry. Disease susceptibility may be associated with variants affecting the gene represented in this entry. Disease susceptibility is associated with variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CLCN2_HUMAN CLCN2_HUMAN] Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (PubMed:29403011, PubMed:29403012).<ref>PMID:19153159</ref> <ref>PMID:19191339</ref> <ref>PMID:29403011</ref> <ref>PMID:29403012</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Wang L]]

OCA at 04:42, 7 April 2023

2023-04-07T04:42:20Z

←Older revision		Revision as of 04:42, 7 April 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7xf5 is ON HOLD	+	The entry 7xf5 is ON HOLD until 2024-05-03

	Authors:		Authors:

OCA: Protected "7xf5" [edit=sysop:move=sysop]

2022-04-06T09:17:42Z

Protected "7xf5" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:17, 6 April 2022

OCA: New page: '''Unreleased structure''' The entry 7xf5 is ON HOLD Authors: Description: Category: Unreleased Structures

2022-04-06T09:17:41Z

New page: '''Unreleased structure''' The entry 7xf5 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7xf5 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]