OCA at 05:36, 5 July 2023

2023-07-05T05:36:51Z

←Older revision		Revision as of 05:36, 5 July 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7y0b is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of human short-chain acyl-CoA dehydrogenase==
-		+	<StructureSection load='7y0b' size='340' side='right'caption='[[7y0b]], [[Resolution\|resolution]] 2.08Å' scene=''>
-	~~Authors~~: ~~Huang~~, Y., Xu, Y., Li, J.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7y0b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y0B FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure~~ of ~~human~~ short-chain acyl-CoA dehydrogenase	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.076Å</td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7R3:(2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol'>7R3</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
-	[[Category: ~~Li, J~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y0b OCA], [https://pdbe.org/7y0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y0b RCSB], [https://www.ebi.ac.uk/pdbsum/7y0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y0b ProSAT]</span></td></tr>
-	[[Category: ~~Xu,~~ Y]]	+	</table>
-	[[Category: ~~Huang,~~ Y]]	+	== Disease ==
		+	[https://www.uniprot.org/uniprot/ACADS_HUMAN ACADS_HUMAN] Short chain acyl-CoA dehydrogenase deficiency. The disease is caused by variants affecting the gene represented in this entry.
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ACADS_HUMAN ACADS_HUMAN] Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats (By similarity). The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (By similarity). Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains (PubMed:21237683, PubMed:11134486).[UniProtKB:P15651]<ref>PMID:11134486</ref> <ref>PMID:21237683</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Huang Y]]
		+	[[Category: Li J]]
		+	[[Category: Xu Y]]

OCA at 03:57, 13 July 2022

2022-07-13T03:57:48Z

←Older revision		Revision as of 03:57, 13 July 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7y0b is ON HOLD	+	The entry 7y0b is ON HOLD until Paper Publication

	Authors: Huang, Y., Xu, Y., Li, J.		Authors: Huang, Y., Xu, Y., Li, J.

OCA: Protected "7y0b" [edit=sysop:move=sysop]

2022-06-15T03:56:43Z

Protected "7y0b" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:56, 15 June 2022

OCA: New page: '''Unreleased structure''' The entry 7y0b is ON HOLD Authors: Huang, Y., Xu, Y., Li, J. Description: Crystal structure of human short-chain acyl-CoA dehydrogenase [[Category: Unrelease...

2022-06-15T03:56:42Z

New page: '''Unreleased structure''' The entry 7y0b is ON HOLD Authors: Huang, Y., Xu, Y., Li, J. Description: Crystal structure of human short-chain acyl-CoA dehydrogenase [[Category: Unrelease...

New page

'''Unreleased structure'''

The entry 7y0b is ON HOLD

Authors: Huang, Y., Xu, Y., Li, J.

Description: Crystal structure of human short-chain acyl-CoA dehydrogenase
[[Category: Unreleased Structures]]
[[Category: Li, J]]
[[Category: Xu, Y]]
[[Category: Huang, Y]]

7y0b - Revision history

OCA at 05:36, 5 July 2023

OCA at 03:57, 13 July 2022

OCA: Protected "7y0b" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 7y0b is ON HOLD Authors: Huang, Y., Xu, Y., Li, J. Description: Crystal structure of human short-chain acyl-CoA dehydrogenase [[Category: Unrelease...