7y79 - Revision history

OCA at 19:46, 29 May 2024

2024-05-29T19:46:47Z

←Older revision		Revision as of 19:46, 29 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7y79]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y79 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7y79]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y79 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y79 OCA], [https://pdbe.org/7y79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y79 RCSB], [https://www.ebi.ac.uk/pdbsum/7y79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y79 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.32Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y79 OCA], [https://pdbe.org/7y79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y79 RCSB], [https://www.ebi.ac.uk/pdbsum/7y79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y79 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/A0A3S6Q0Y2_BACTU A0A3S6Q0Y2_BACTU]]	+	[https://www.uniprot.org/uniprot/A0A3S6Q0Y2_BACTU A0A3S6Q0Y2_BACTU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 19:33, 7 September 2022

2022-09-07T19:33:48Z

←Older revision		Revision as of 19:33, 7 September 2022
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	==Crystal structure of Cry78Aa==		==Crystal structure of Cry78Aa==
-	<StructureSection load='7y79' size='340' side='right'caption='[[7y79]]' scene=''>	+	<StructureSection load='7y79' size='340' side='right'caption='[[7y79]], [[Resolution\|resolution]] 2.32Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y79 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7y79]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y79 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y79 OCA], [https://pdbe.org/7y79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y79 RCSB], [https://www.ebi.ac.uk/pdbsum/7y79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y79 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y79 OCA], [https://pdbe.org/7y79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y79 RCSB], [https://www.ebi.ac.uk/pdbsum/7y79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y79 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[https://www.uniprot.org/uniprot/A0A3S6Q0Y2_BACTU A0A3S6Q0Y2_BACTU]]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Genetically modified plants with insecticidal proteins from Bacillus thuringiensis (Bt) have been successfully utilized to control various kinds of pests in crop production and reduce the abuse of pesticides. However, a limited number of genes are available for the protection of crops from rice planthopper. Recently, Cry78Aa protein from Bt strain C9F1 has been found to have high insecticidal activity against Laodelphax striatellus and Nilaparvata lugens. It is the first reported single-component protein in the world to combat rice planthoppers, making it very promising for use in transgenic crops. The ambiguous mechanism of Cry78Aa functions prevented further engineering or application. Here, we report the crystal structure of Cry78Aa, which consists of two domains: a C-terminal beta-pore forming domain belonging to the aerolysin family and an N-terminal trefoil domain resembling the S-type ricin B lectin. Thus, Cry78Aa could represent a distinctive type of beta-pore forming toxin. We also found that Cry78Aa binds carbohydrates such as galactose derivatives and is essential for insecticidal activity against Laodelphax striatellus. Our results suggest a mechanism underlying the function of Cry78Aa against rice planthoppers and pave the way to maximizing the usage of the toxin.
		+
		+	The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity.,Cao B, Nie Y, Guan Z, Chen C, Wang N, Wang Z, Shu C, Zhang J, Zhang D Commun Biol. 2022 Aug 9;5(1):801. doi: 10.1038/s42003-022-03754-6. PMID:35945427<ref>PMID:35945427</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7y79" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus thuringiensis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Cao BB]]		[[Category: Cao BB]]

OCA at 06:38, 31 August 2022

2022-08-31T06:38:48Z

←Older revision		Revision as of 06:38, 31 August 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7y79 is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of Cry78Aa==
-		+	<StructureSection load='7y79' size='340' side='right'caption='[[7y79]]' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y79 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y79 OCA], [https://pdbe.org/7y79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y79 RCSB], [https://www.ebi.ac.uk/pdbsum/7y79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y79 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Cao BB]]
		+	[[Category: Guan ZY]]
		+	[[Category: Nie YF]]
		+	[[Category: Wang NC]]
		+	[[Category: Zhang DL]]
		+	[[Category: Zhang J]]

OCA at 03:42, 10 August 2022

2022-08-10T03:42:10Z

←Older revision		Revision as of 03:42, 10 August 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7y79 is ON HOLD	+	The entry 7y79 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7y79" [edit=sysop:move=sysop]

2022-06-29T06:10:19Z

Protected "7y79" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:10, 29 June 2022

OCA: New page: '''Unreleased structure''' The entry 7y79 is ON HOLD Authors: Description: Category: Unreleased Structures

2022-06-29T06:10:18Z

New page: '''Unreleased structure''' The entry 7y79 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7y79 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]