7yzy - Revision history

OCA at 12:55, 22 February 2023

2023-02-22T12:55:07Z

←Older revision		Revision as of 12:55, 22 February 2023
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-	====	+	==pMMO structure from native membranes by cryoET and STA==
-	<StructureSection load='7yzy' size='340' side='right'caption='[[7yzy]]' scene=''>	+	<StructureSection load='7yzy' size='340' side='right'caption='[[7yzy]], [[Resolution\|resolution]] 4.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[7yzy]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylococcus_capsulatus_str._Bath Methylococcus capsulatus str. Bath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YZY FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yzy OCA], [https://pdbe.org/7yzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yzy RCSB], [https://www.ebi.ac.uk/pdbsum/7yzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yzy ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yzy OCA], [https://pdbe.org/7yzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yzy RCSB], [https://www.ebi.ac.uk/pdbsum/7yzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yzy ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PMOA_METCA PMOA_METCA]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Methane-oxidizing bacteria play a central role in greenhouse gas mitigation and have potential applications in biomanufacturing. Their primary metabolic enzyme, particulate methane monooxygenase (pMMO), is housed in copper-induced intracytoplasmic membranes (ICMs), of which the function and biogenesis are not known. We show by serial cryo-focused ion beam (cryoFIB) milling/scanning electron microscope (SEM) volume imaging and lamellae-based cellular cryo-electron tomography (cryoET) that these ICMs are derived from the inner cell membrane. The pMMO trimer, resolved by cryoET and subtomogram averaging to 4.8 A in the ICM, forms higher-order hexagonal arrays in intact cells. Array formation correlates with increased enzymatic activity, highlighting the importance of studying the enzyme in its native environment. These findings also demonstrate the power of cryoET to structurally characterize native membrane enzymes in the cellular context.
		+
		+	Structure and activity of particulate methane monooxygenase arrays in methanotrophs.,Zhu Y, Koo CW, Cassidy CK, Spink MC, Ni T, Zanetti-Domingues LC, Bateman B, Martin-Fernandez ML, Shen J, Sheng Y, Song Y, Yang Z, Rosenzweig AC, Zhang P Nat Commun. 2022 Sep 5;13(1):5221. doi: 10.1038/s41467-022-32752-9. PMID:36064719<ref>PMID:36064719</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 7yzy" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Z-disk~~]]	+	[[Category: Methylococcus capsulatus str. Bath]]
		+	[[Category: Ni T]]
		+	[[Category: Zhang P]]
		+	[[Category: Zhu Y]]

OCA at 05:02, 10 August 2022

2022-08-10T05:02:51Z

←Older revision		Revision as of 05:02, 10 August 2022
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-	'''Unreleased structure'''

-	~~The entry~~ 7yzy ~~is ON HOLD until Paper Publication~~	+	====
-		+	<StructureSection load='7yzy' size='340' side='right'caption='[[7yzy]]' scene=''>
-	~~Authors~~: ~~Zhu, Y~~.~~, Ni, T~~.~~, Zhang, P~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
-	~~Description: pMMO~~ structure ~~from native membranes by cryoET and STA~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yzy OCA], [https://pdbe.org/7yzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yzy RCSB], [https://www.ebi.ac.uk/pdbsum/7yzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yzy ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Zhang~~, P]]	+	__TOC__
-	[[Category: ~~Zhu, Y~~]]	+	</StructureSection>
-	[[Category: ~~Ni, T~~]]	+	[[Category: Large Structures]]
		+	[[Category: Z-disk]]

OCA at 10:37, 27 April 2022

2022-04-27T10:37:41Z

←Older revision		Revision as of 10:37, 27 April 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7yzy is ON HOLD	+	The entry 7yzy is ON HOLD until Paper Publication

	Authors: Zhu, Y., Ni, T., Zhang, P.		Authors: Zhu, Y., Ni, T., Zhang, P.
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	Description: pMMO structure from native membranes by cryoET and STA		Description: pMMO structure from native membranes by cryoET and STA
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Ni, T]]
	[[Category: Zhang, P]]		[[Category: Zhang, P]]
	[[Category: Zhu, Y]]		[[Category: Zhu, Y]]
		+	[[Category: Ni, T]]

OCA: Protected "7yzy" [edit=sysop:move=sysop]

2022-03-02T05:21:14Z

Protected "7yzy" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:21, 2 March 2022

OCA: New page: '''Unreleased structure''' The entry 7yzy is ON HOLD Authors: Zhu, Y., Ni, T., Zhang, P. Description: pMMO structure from native membranes by cryoET and STA [[Category: Unreleased Stru...

2022-03-02T05:21:13Z

New page: '''Unreleased structure''' The entry 7yzy is ON HOLD Authors: Zhu, Y., Ni, T., Zhang, P. Description: pMMO structure from native membranes by cryoET and STA [[Category: Unreleased Stru...

New page

'''Unreleased structure'''

The entry 7yzy is ON HOLD

Authors: Zhu, Y., Ni, T., Zhang, P.

Description: pMMO structure from native membranes by cryoET and STA
[[Category: Unreleased Structures]]
[[Category: Ni, T]]
[[Category: Zhang, P]]
[[Category: Zhu, Y]]