7zl3 - Revision history

OCA at 10:08, 6 September 2023

2023-09-06T10:08:09Z

←Older revision		Revision as of 10:08, 6 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7zl3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZL3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7zl3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZL3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3EG:(2S)-2-AMINO-4,4,4-TRIFLUOROBUTANOIC+ACID'>3EG</scene>, <scene name='pdbligand=JMO:(2R)-4-cyano-2-[(2~{S})-2-(methylamino)propanoyl]oxy-butanoic+acid'>JMO</scene>, <scene name='pdbligand=JMX:(2S)-3-[1-[(4-bromophenyl)methyl]indol-3-yl]-2-(methylamino)propanoic+acid'>JMX</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3EG:(2S)-2-AMINO-4,4,4-TRIFLUOROBUTANOIC+ACID'>3EG</scene>, <scene name='pdbligand=JMO:(2R)-4-cyano-2-[(2~{S})-2-(methylamino)propanoyl]oxy-butanoic+acid'>JMO</scene>, <scene name='pdbligand=JMX:(2S)-3-[1-[(4-bromophenyl)methyl]indol-3-yl]-2-(methylamino)propanoic+acid'>JMX</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zl3 OCA], [https://pdbe.org/7zl3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zl3 RCSB], [https://www.ebi.ac.uk/pdbsum/7zl3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zl3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zl3 OCA], [https://pdbe.org/7zl3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zl3 RCSB], [https://www.ebi.ac.uk/pdbsum/7zl3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zl3 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:19, 22 March 2023

2023-03-22T07:19:35Z

←Older revision		Revision as of 07:19, 22 March 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 7zl3 ~~is ON HOLD~~	+	==Signal peptide mimicry primes Sec61 for client-selective inhibition==
-		+	<StructureSection load='7zl3' size='340' side='right'caption='[[7zl3]], [[Resolution\|resolution]] 3.20Å' scene=''>
-	~~Authors~~: ~~Rehan~~, S., ~~Paavilainen O~~, V.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[7zl3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZL3 FirstGlance]. <br>
-	~~Description~~: ~~Signal peptide mimicry primes Sec61 for client-selective inhibition~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3EG:(2S)-2-AMINO-4,4,4-TRIFLUOROBUTANOIC+ACID'>3EG</scene>, <scene name='pdbligand=JMO:(2R)-4-cyano-2-[(2~{S})-2-(methylamino)propanoyl]oxy-butanoic+acid'>JMO</scene>, <scene name='pdbligand=JMX:(2S)-3-[1-[(4-bromophenyl)methyl]indol-3-yl]-2-(methylamino)propanoic+acid'>JMX</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zl3 OCA], [https://pdbe.org/7zl3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zl3 RCSB], [https://www.ebi.ac.uk/pdbsum/7zl3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zl3 ProSAT]</span></td></tr>
-	[[Category: Paavilainen O, V]]	+	</table>
-	[[Category: Rehan, S]]	+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A6P3YN15_SHEEP A0A6P3YN15_SHEEP]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Ovis aries]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Paavilainen O V]]
		+	[[Category: Rehan S]]

OCA at 03:41, 25 August 2022

2022-08-25T03:41:12Z

←Older revision		Revision as of 03:41, 25 August 2022
Line 3:		Line 3:
	The entry 7zl3 is ON HOLD		The entry 7zl3 is ON HOLD

-	Authors: ~~Shahid~~, R., ~~Ville~~, P.	+	Authors: Rehan, S., Paavilainen O, V.

-	Description: ~~Mammalian~~ Sec61 ~~translocon bound to KZR445~~	+	Description: Signal peptide mimicry primes Sec61 for client-selective inhibition
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Shahid~~, R]]	+	[[Category: Paavilainen O, V]]
-	[[Category: ~~Ville~~, P]]	+	[[Category: Rehan, S]]

OCA at 07:12, 22 June 2022

2022-06-22T07:12:36Z

←Older revision		Revision as of 07:12, 22 June 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7zl3 is ON HOLD ~~until sometime in the future~~	+	The entry 7zl3 is ON HOLD

	Authors: Shahid, R., Ville, P.		Authors: Shahid, R., Ville, P.

OCA at 09:15, 18 May 2022

2022-05-18T09:15:55Z

←Older revision		Revision as of 09:15, 18 May 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 7zl3 is ON HOLD	+	The entry 7zl3 is ON HOLD until sometime in the future

	Authors: Shahid, R., Ville, P.		Authors: Shahid, R., Ville, P.

OCA: Protected "7zl3" [edit=sysop:move=sysop]

2022-04-21T01:53:11Z

Protected "7zl3" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:53, 21 April 2022

OCA: New page: '''Unreleased structure''' The entry 7zl3 is ON HOLD Authors: Shahid, R., Ville, P. Description: Mammalian Sec61 translocon bound to KZR445 Category: Unreleased Structures [[Catego...

2022-04-21T01:53:10Z

New page: '''Unreleased structure''' The entry 7zl3 is ON HOLD Authors: Shahid, R., Ville, P. Description: Mammalian Sec61 translocon bound to KZR445 Category: Unreleased Structures [[Catego...

New page

'''Unreleased structure'''

The entry 7zl3 is ON HOLD

Authors: Shahid, R., Ville, P.

Description: Mammalian Sec61 translocon bound to KZR445
[[Category: Unreleased Structures]]
[[Category: Shahid, R]]
[[Category: Ville, P]]