8e1i - Revision history

OCA at 10:16, 25 October 2023

2023-10-25T10:16:46Z

←Older revision		Revision as of 10:16, 25 October 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8e1i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe/Puccinia_graminis_mixed_DNA_library Schizosaccharomyces pombe/Puccinia graminis mixed DNA library]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E1I FirstGlance]. <br>		<table><tr><td colspan='2'>[[8e1i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe/Puccinia_graminis_mixed_DNA_library Schizosaccharomyces pombe/Puccinia graminis mixed DNA library]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E1I FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=I7P:(1R,2R,3S,4S,5R,6S)-2,3,4,5,6-PENTAKIS(PHOSPHONOOXY)CYCLOHEXYL+TRIHYDROGEN+DIPHOSPHATE'>I7P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=I7P:(1R,2R,3S,4S,5R,6S)-2,3,4,5,6-PENTAKIS(PHOSPHONOOXY)CYCLOHEXYL+TRIHYDROGEN+DIPHOSPHATE'>I7P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e1i OCA], [https://pdbe.org/8e1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e1i RCSB], [https://www.ebi.ac.uk/pdbsum/8e1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e1i ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e1i OCA], [https://pdbe.org/8e1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e1i RCSB], [https://www.ebi.ac.uk/pdbsum/8e1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e1i ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:46, 30 November 2022

2022-11-30T10:46:44Z

←Older revision		Revision as of 10:46, 30 November 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8e1i is ~~ON HOLD until Paper Publication~~	+	==Asp1 kinase in complex with ATP Mg 5-IP7==
-		+	<StructureSection load='8e1i' size='340' side='right'caption='[[8e1i]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~Authors~~: ~~Goldgur~~, Y., ~~Shuman~~, S., ~~Benjamin~~, B.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8e1i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe/Puccinia_graminis_mixed_DNA_library Schizosaccharomyces pombe/Puccinia graminis mixed DNA library]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E1I FirstGlance]. <br>
-	~~Description~~: ~~Asp1~~ kinase in ~~complex~~ with ~~ATP Mg 5~~-~~IP7~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=I7P:(1R,2R,3S,4S,5R,6S)-2,3,4,5,6-PENTAKIS(PHOSPHONOOXY)CYCLOHEXYL+TRIHYDROGEN+DIPHOSPHATE'>I7P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e1i OCA], [https://pdbe.org/8e1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e1i RCSB], [https://www.ebi.ac.uk/pdbsum/8e1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e1i ProSAT]</span></td></tr>
-	[[Category: Benjamin, B]]	+	</table>
-	[[Category: Goldgur, Y]]	+	== Function ==
-	[[Category: Shuman, S]]	+	[https://www.uniprot.org/uniprot/VIP1_SCHPO VIP1_SCHPO] Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. Phosphorylates inositol hexakisphosphate (InsP6) at position 1 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4. Alternatively, phosphorylates PP-InsP5 at position 1, produced by IP6Ks from InsP6, to produce (PP)2-InsP4 (By similarity). Required for maintaining cellular integrity, normal growth and interactions with the ARP complex (PubMed:10388810). Acts as a regulator of the PHO80-PHO85 cyclin/cyclin-dependent kinase (CDK) complex, thereby regulating signaling of phosphate availability (By similarity). Required for the function of the cortical actin cytoskeleton, possibly by participating in correct F-actin localization and ensuring polarized growth (PubMed:10388810). Regulates polarized growth and modulates interphase microtubule cytoskeleton. Regulates microtubule dynamics without the requirement of microtubule plus-end tracking protein Mal3. Required for growth zone selection (PubMed:25254656).[UniProtKB:O43314][UniProtKB:Q06685]<ref>PMID:10388810</ref> <ref>PMID:25254656</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Schizosaccharomyces pombe/Puccinia graminis mixed DNA library]]
		+	[[Category: Benjamin B]]
		+	[[Category: Goldgur Y]]
		+	[[Category: Shuman S]]

OCA at 03:50, 25 August 2022

2022-08-25T03:50:25Z

←Older revision		Revision as of 03:50, 25 August 2022
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8e1i is ON HOLD	+	The entry 8e1i is ON HOLD until Paper Publication

	Authors: Goldgur, Y., Shuman, S., Benjamin, B.		Authors: Goldgur, Y., Shuman, S., Benjamin, B.

OCA: Protected "8e1i" [edit=sysop:move=sysop]

2022-08-18T04:14:51Z

Protected "8e1i" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:14, 18 August 2022

OCA: New page: '''Unreleased structure''' The entry 8e1i is ON HOLD Authors: Goldgur, Y., Shuman, S., Benjamin, B. Description: Asp1 kinase in complex with ATP Mg 5-IP7 [[Category: Unreleased Structu...

2022-08-18T04:14:50Z

New page: '''Unreleased structure''' The entry 8e1i is ON HOLD Authors: Goldgur, Y., Shuman, S., Benjamin, B. Description: Asp1 kinase in complex with ATP Mg 5-IP7 [[Category: Unreleased Structu...

New page

'''Unreleased structure'''

The entry 8e1i is ON HOLD

Authors: Goldgur, Y., Shuman, S., Benjamin, B.

Description: Asp1 kinase in complex with ATP Mg 5-IP7
[[Category: Unreleased Structures]]
[[Category: Benjamin, B]]
[[Category: Goldgur, Y]]
[[Category: Shuman, S]]