8e6b - Revision history

OCA at 10:18, 25 October 2023

2023-10-25T10:18:02Z

←Older revision		Revision as of 10:18, 25 October 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8e6b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E6B FirstGlance]. <br>		<table><tr><td colspan='2'>[[8e6b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E6B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UO9:(2~{S})-2-[[(2~{S})-4-methyl-2-[[2-methyl-2-[oxidanyl(phenyl)-$l^{3}-sulfanyl]propoxy]carbonylamino]pentanoyl]amino]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propane-1-sulfonic+acid'>UO9</scene>, <scene name='pdbligand=URR:N~2~-(ethoxycarbonyl)-N-{(1S,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-1-sulfanylpropan-2-yl}-L-leucinamide'>URR</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UO9:(2~{S})-2-[[(2~{S})-4-methyl-2-[[2-methyl-2-[oxidanyl(phenyl)-$l^{3}-sulfanyl]propoxy]carbonylamino]pentanoyl]amino]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propane-1-sulfonic+acid'>UO9</scene>, <scene name='pdbligand=URR:N~2~-(ethoxycarbonyl)-N-{(1S,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-1-sulfanylpropan-2-yl}-L-leucinamide'>URR</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e6b OCA], [https://pdbe.org/8e6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e6b RCSB], [https://www.ebi.ac.uk/pdbsum/8e6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e6b ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e6b OCA], [https://pdbe.org/8e6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e6b RCSB], [https://www.ebi.ac.uk/pdbsum/8e6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e6b ProSAT]</span></td></tr>
	</table>		</table>

OCA at 17:16, 26 April 2023

2023-04-26T17:16:52Z

←Older revision		Revision as of 17:16, 26 April 2023
Line 8:		Line 8:
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/A0A1L2E0X0_MERS A0A1L2E0X0_MERS]]	+	[https://www.uniprot.org/uniprot/A0A1L2E0X0_MERS A0A1L2E0X0_MERS]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 16:42, 7 September 2022

2022-09-07T16:42:56Z

←Older revision		Revision as of 16:42, 7 September 2022
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8e6b ~~is ON HOLD~~	+	==Crystal structure of MERS 3CL protease in complex with a dimethyl sulfinyl benzene inhibitor==
-		+	<StructureSection load='8e6b' size='340' side='right'caption='[[8e6b]], [[Resolution\|resolution]] 1.55Å' scene=''>
-	~~Authors~~: ~~Liu~~, L., ~~Lovell~~, S., ~~Battaile, K~~.P., ~~Dampalla, C~~.S., ~~Groutas, W~~.C.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8e6b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E6B FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of MERS 3CL protease in complex with a dimethyl sulfinyl benzene inhibitor~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UO9:(2~{S})-2-[[(2~{S})-4-methyl-2-[[2-methyl-2-[oxidanyl(phenyl)-$l^{3}-sulfanyl]propoxy]carbonylamino]pentanoyl]amino]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propane-1-sulfonic+acid'>UO9</scene>, <scene name='pdbligand=URR:N~2~-(ethoxycarbonyl)-N-{(1S,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-1-sulfanylpropan-2-yl}-L-leucinamide'>URR</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e6b OCA], [https://pdbe.org/8e6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e6b RCSB], [https://www.ebi.ac.uk/pdbsum/8e6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e6b ProSAT]</span></td></tr>
-	[[Category: ~~Battaile, K.P~~]]	+	</table>
-	[[Category: ~~Liu, L~~]]	+	== Function ==
-	[[Category: ~~Lovell, S~~]]	+	[[https://www.uniprot.org/uniprot/A0A1L2E0X0_MERS A0A1L2E0X0_MERS]]
-	[[Category: Groutas~~, W.C~~]]	+	__TOC__
-	[[Category: ~~Dampalla, C.~~S]]	+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Middle East respiratory syndrome-related coronavirus]]
		+	[[Category: Battaile KP]]
		+	[[Category: Dampalla CS]]
		+	[[Category: Groutas WC]]
		+	[[Category: Liu L]]
		+	[[Category: Lovell S]]

OCA: Protected "8e6b" [edit=sysop:move=sysop]

2022-08-31T05:36:20Z

Protected "8e6b" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:36, 31 August 2022

OCA: New page: '''Unreleased structure''' The entry 8e6b is ON HOLD Authors: Liu, L., Lovell, S., Battaile, K.P., Dampalla, C.S., Groutas, W.C. Description: Crystal structure of MERS 3CL protease in ...

2022-08-31T05:36:19Z

New page: '''Unreleased structure''' The entry 8e6b is ON HOLD Authors: Liu, L., Lovell, S., Battaile, K.P., Dampalla, C.S., Groutas, W.C. Description: Crystal structure of MERS 3CL protease in ...

New page

'''Unreleased structure'''

The entry 8e6b is ON HOLD

Authors: Liu, L., Lovell, S., Battaile, K.P., Dampalla, C.S., Groutas, W.C.

Description: Crystal structure of MERS 3CL protease in complex with a dimethyl sulfinyl benzene inhibitor
[[Category: Unreleased Structures]]
[[Category: Battaile, K.P]]
[[Category: Liu, L]]
[[Category: Lovell, S]]
[[Category: Groutas, W.C]]
[[Category: Dampalla, C.S]]