8flf - Revision history

OCA at 08:00, 1 May 2024

2024-05-01T08:00:23Z

←Older revision		Revision as of 08:00, 1 May 2024
Line 12:		Line 12:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/RL11_HUMAN RL11_HUMAN] Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity).<ref>PMID:19061985</ref>		[https://www.uniprot.org/uniprot/RL11_HUMAN RL11_HUMAN] Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity).<ref>PMID:19061985</ref>
		+
		+	==See Also==
		+	*[[Ribosome 3D structures\|Ribosome 3D structures]]
		+	*[[Ribosome biogenesis protein 3D structures\|Ribosome biogenesis protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:22, 12 July 2023

2023-07-12T07:22:11Z

←Older revision		Revision as of 07:22, 12 July 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8flf is ~~ON HOLD until Paper Publication~~	+	==Human nuclear pre-60S ribosomal subunit (State L3)==
-		+	<StructureSection load='8flf' size='340' side='right'caption='[[8flf]], [[Resolution\|resolution]] 2.65Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8flf]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FLF FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.65Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=6MZ:N6-METHYLADENOSINE-5-MONOPHOSPHATE'>6MZ</scene>, <scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8flf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8flf OCA], [https://pdbe.org/8flf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8flf RCSB], [https://www.ebi.ac.uk/pdbsum/8flf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8flf ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/RL11_HUMAN RL11_HUMAN] Blackfan-Diamond disease. Diamond-Blackfan anemia 7 (DBA7) [MIM:[https://omim.org/entry/612562 612562]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:19061985</ref> <ref>PMID:19191325</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/RL11_HUMAN RL11_HUMAN] Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity).<ref>PMID:19061985</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Klinge S]]
		+	[[Category: Vanden Broeck A]]

OCA at 05:26, 18 May 2023

2023-05-18T05:26:17Z

←Older revision		Revision as of 05:26, 18 May 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8flf is ON HOLD	+	The entry 8flf is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 05:02, 10 May 2023

2023-05-10T05:02:06Z

←Older revision		Revision as of 05:02, 10 May 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8flf is ON HOLD ~~until Paper Publication~~	+	The entry 8flf is ON HOLD

	Authors:		Authors:

OCA at 09:21, 1 February 2023

2023-02-01T09:21:44Z

←Older revision		Revision as of 09:21, 1 February 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8flf is ON HOLD	+	The entry 8flf is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8flf" [edit=sysop:move=sysop]

2022-12-28T06:10:53Z

Protected "8flf" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:10, 28 December 2022

OCA: New page: '''Unreleased structure''' The entry 8flf is ON HOLD Authors: Description: Category: Unreleased Structures

2022-12-28T06:10:49Z

New page: '''Unreleased structure''' The entry 8flf is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8flf is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]