8fwm - Revision history

OCA at 08:00, 6 December 2023

2023-12-06T08:00:15Z

←Older revision		Revision as of 08:00, 6 December 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8fwm is ~~ON HOLD~~	+	==Structure of tail-neck junction of Agrobacterium phage Milano==
		+	<StructureSection load='8fwm' size='340' side='right'caption='[[8fwm]], [[Resolution\|resolution]] 3.49Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8fwm]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_phage_Milano Agrobacterium phage Milano]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FWM FirstGlance]. <br>
		+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.49Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fwm OCA], [https://pdbe.org/8fwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fwm RCSB], [https://www.ebi.ac.uk/pdbsum/8fwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fwm ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A482MGH3_9CAUD A0A482MGH3_9CAUD]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Large gaps exist in our understanding of how bacteriophages, the most abundant biological entities on Earth, assemble and function. The structure of the "neck" region, where the DNA-filled capsid is connected to the host-recognizing tail remains poorly understood. We describe cryo-EM structures of the neck, the neck-capsid and neck-tail junctions, and capsid of the Agrobacterium phage Milano. The Milano neck 1 protein connects the 12-fold symmetrical neck to a 5-fold vertex of the icosahedral capsid. Comparison of Milano neck 1 homologs leads to four proposed classes, likely evolved from the simplest one in siphophages to more complex ones in myo- and podophages. Milano neck is surrounded by the atypical collar, which covalently crosslinks the tail sheath to neck 1. The Milano capsid is decorated with three types of proteins, a minor capsid protein (mCP) and two linking proteins crosslinking the mCP to the major capsid protein. The extensive network of disulfide bonds within and between neck, collar, capsid and tail provides an exceptional structural stability to Milano.

-	~~Authors: Sonani, R.R~~., ~~Wang, F.~~, Esteves, ~~N.C.~~, Kelly~~, R.J.~~, Sebastian, A., Kreutzberger~~, M.A.B.~~, Leiman~~, P.G.~~, Scharf, B.E.~~, Egelman, E~~.H.	+	Neck and capsid architecture of the robust Agrobacterium phage Milano.,Sonani RR, Esteves NC, Horton AA, Kelly RJ, Sebastian AL, Wang F, Kreutzberger MAB, Leiman PG, Scharf BE, Egelman EH Commun Biol. 2023 Sep 8;6(1):921. doi: 10.1038/s42003-023-05292-1. PMID:37684529<ref>PMID:37684529</ref>

-	~~Description: Structure~~ of ~~tail-neck junction~~ of Agrobacterium phage Milano	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: ~~Scharf, B.E~~]]	+	<div class="pdbe-citations 8fwm" style="background-color:#fffaf0;"></div>
-	[[Category: Esteves~~, N.C~~]]	+	== References ==
-	[[Category: ~~Sonani, R.R~~]]	+	<references/>
-	[[Category: ~~Egelman, E.H~~]]	+	__TOC__
-	[[Category: ~~Kelly, R.J~~]]	+	</StructureSection>
-	[[Category: ~~Wang, F~~]]	+	[[Category: Agrobacterium phage Milano]]
-	[[Category: ~~Leiman, P.G~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Kreutzberger, M.A.B~~]]	+	[[Category: Egelman EH]]
-	[[Category: ~~Sebastian, A~~]]	+	[[Category: Esteves NC]]
		+	[[Category: Kelly RJ]]
		+	[[Category: Kreutzberger MAB]]
		+	[[Category: Leiman PG]]
		+	[[Category: Scharf BE]]
		+	[[Category: Sebastian A]]
		+	[[Category: Sonani RR]]
		+	[[Category: Wang F]]

OCA at 08:44, 15 February 2023

2023-02-15T08:44:11Z

←Older revision		Revision as of 08:44, 15 February 2023
Line 5:		Line 5:
	Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelman, E.H.		Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelman, E.H.

-	Description: Structure of Agrobacterium ~~tumefaciens bacteriophage~~ Milano ~~Tail-to-Neck junction~~	+	Description: Structure of tail-neck junction of Agrobacterium phage Milano
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Scharf, B.E]]
		+	[[Category: Esteves, N.C]]
	[[Category: Sonani, R.R]]		[[Category: Sonani, R.R]]
	[[Category: Egelman, E.H]]		[[Category: Egelman, E.H]]
	[[Category: Kelly, R.J]]		[[Category: Kelly, R.J]]
-	[[Category: Leiman, P.G]]
-	[[Category: Scharf, B.E]]
-	[[Category: Esteves, N.C]]
	[[Category: Wang, F]]		[[Category: Wang, F]]
		+	[[Category: Leiman, P.G]]
	[[Category: Kreutzberger, M.A.B]]		[[Category: Kreutzberger, M.A.B]]
	[[Category: Sebastian, A]]		[[Category: Sebastian, A]]

OCA: Protected "8fwm" [edit=sysop:move=sysop]

2023-02-01T09:26:45Z

Protected "8fwm" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:26, 1 February 2023

OCA: New page: '''Unreleased structure''' The entry 8fwm is ON HOLD Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelma...

2023-02-01T09:26:43Z

New page: '''Unreleased structure''' The entry 8fwm is ON HOLD Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelma...

New page

'''Unreleased structure'''

The entry 8fwm is ON HOLD

Authors: Sonani, R.R., Wang, F., Esteves, N.C., Kelly, R.J., Sebastian, A., Kreutzberger, M.A.B., Leiman, P.G., Scharf, B.E., Egelman, E.H.

Description: Structure of Agrobacterium tumefaciens bacteriophage Milano Tail-to-Neck junction
[[Category: Unreleased Structures]]
[[Category: Sonani, R.R]]
[[Category: Egelman, E.H]]
[[Category: Kelly, R.J]]
[[Category: Leiman, P.G]]
[[Category: Scharf, B.E]]
[[Category: Esteves, N.C]]
[[Category: Wang, F]]
[[Category: Kreutzberger, M.A.B]]
[[Category: Sebastian, A]]