8gq0 - Revision history

OCA at 11:12, 2 August 2023

2023-08-02T11:12:18Z

←Older revision		Revision as of 11:12, 2 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8gq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GQ0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[8gq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GQ0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCL:~{N}-[2-(1~{H}-indol-3-yl)ethyl]-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-amine'>KCL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.44Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCL:~{N}-[2-(1~{H}-indol-3-yl)ethyl]-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-amine'>KCL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gq0 OCA], [https://pdbe.org/8gq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gq0 RCSB], [https://www.ebi.ac.uk/pdbsum/8gq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gq0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gq0 OCA], [https://pdbe.org/8gq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gq0 RCSB], [https://www.ebi.ac.uk/pdbsum/8gq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gq0 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:34, 18 January 2023

2023-01-18T07:34:19Z

←Older revision		Revision as of 07:34, 18 January 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8gq0 is ~~ON HOLD~~	+	==Crystal structure of BRD4 bromodomain 1 (BD1) in complex with STL233497==
-		+	<StructureSection load='8gq0' size='340' side='right'caption='[[8gq0]], [[Resolution\|resolution]] 1.44Å' scene=''>
-	~~Authors~~: ~~Park~~, T.H., ~~Lee~~, B.I.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8gq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GQ0 FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of~~ BRD4 ~~bromodomain 1~~ (~~BD1~~) ~~in complex~~ with ~~STL233497~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCL:~{N}-[2-(1~{H}-indol-3-yl)ethyl]-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-amine'>KCL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gq0 OCA], [https://pdbe.org/8gq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gq0 RCSB], [https://www.ebi.ac.uk/pdbsum/8gq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gq0 ProSAT]</span></td></tr>
-	[[Category: Lee~~, B.I~~]]	+	</table>
-	[[Category: Park~~, T.H~~]]	+	== Disease ==
		+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Lee BI]]
		+	[[Category: Park TH]]

OCA: Protected "8gq0" [edit=sysop:move=sysop]

2022-09-07T15:39:55Z

Protected "8gq0" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:39, 7 September 2022

OCA: New page: '''Unreleased structure''' The entry 8gq0 is ON HOLD Authors: Park, T.H., Lee, B.I. Description: Crystal structure of BRD4 bromodomain 1 (BD1) in complex with STL233497 [[Category: Unr...

2022-09-07T15:39:54Z

New page: '''Unreleased structure''' The entry 8gq0 is ON HOLD Authors: Park, T.H., Lee, B.I. Description: Crystal structure of BRD4 bromodomain 1 (BD1) in complex with STL233497 [[Category: Unr...

New page

'''Unreleased structure'''

The entry 8gq0 is ON HOLD

Authors: Park, T.H., Lee, B.I.

Description: Crystal structure of BRD4 bromodomain 1 (BD1) in complex with STL233497
[[Category: Unreleased Structures]]
[[Category: Lee, B.I]]
[[Category: Park, T.H]]