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8htw - Revision history
2026-04-07T17:45:07Z
Revision history for this page on the wiki
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http://52.214.119.220/wiki/index.php?title=8htw&diff=3716141&oldid=prev
OCA at 10:30, 15 February 2023
2023-02-15T10:30:54Z
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 10:30, 15 February 2023</td>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''Unreleased structure'''</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">The entry </del>8htw <del style="color: red; font-weight: bold; text-decoration: none;">is ON HOLD until Paper Publication</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">==Crystal Structure of the ring nuclease Sso2081 Y133F mutant from Saccharolobus solfataricus in its apo form==</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><StructureSection load='</ins>8htw<ins style="color: red; font-weight: bold; text-decoration: none;">' size='340' side='right'caption='[[8htw]], [[Resolution|resolution]] 2.00&Aring;' scene=''></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Authors</del>: </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Structural highlights ==</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><table><tr><td colspan='2'>[[8htw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HTW OCA]. For a <b>guided tour on the structure components</b> use [https</ins>:<ins style="color: red; font-weight: bold; text-decoration: none;">//proteopedia.org/fgij/fg.htm?mol=8HTW FirstGlance]. <br></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Description</del>: </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8htw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8htw OCA], [https://pdbe.org/8htw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8htw RCSB], [https://www.ebi.ac.uk/pdbsum/8htw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8htw ProSAT]</span></td></tr></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Unreleased </del>Structures]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></table></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Function ==</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[https://www.uniprot.org/uniprot/RN081_SACS2 RN081_SACS2] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (Probable). A nuclease that degrades cyclic oligoadenylates (cOA), second messengers that induce an antiviral state important for defense against invading nucleic acids. Destruction of cOA deactivates the Csx1 ribonuclease, preventing uncontrolled degradation of cellular RNA. Degrades cA4 (a tetraadenylate ring) into a linear diadenylate product with 5'-OH and 2',3'-cyclic phosphate termini. Is 10-fold more active than SSO1393, suggesting this is the major cA4 degradation enzyme. Is highly specific for cA4; it has very poor activity on cA6 and no discernible activity against a number of cyclic dinucletides. There may be 2 active sites per homodimer (PubMed:30232454).<ref>PMID</ins>:<ins style="color: red; font-weight: bold; text-decoration: none;">30232454</ref> </ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== References ==</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><references/></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">__TOC__</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></StructureSection></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Large </ins>Structures<ins style="color: red; font-weight: bold; text-decoration: none;">]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Saccharolobus solfataricus P2]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Du L]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Lin Z]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Luo Z</ins>]]</div></td></tr>
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OCA
http://52.214.119.220/wiki/index.php?title=8htw&diff=3690544&oldid=prev
OCA: Protected "8htw" [edit=sysop:move=sysop]
2022-12-28T06:37:18Z
<p>Protected "<a href="/wiki/index.php/8htw" title="8htw">8htw</a>" [edit=sysop:move=sysop]</p>
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 06:37, 28 December 2022</td>
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OCA
http://52.214.119.220/wiki/index.php?title=8htw&diff=3690543&oldid=prev
OCA: New page: '''Unreleased structure''' The entry 8htw is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures
2022-12-28T06:37:13Z
<p>New page: '''Unreleased structure''' The entry 8htw is ON HOLD until Paper Publication Authors: Description: <a href="/wiki/index.php/Category:Unreleased_Structures" title="Category:Unreleased Structures">Category: Unreleased Structures</a></p>
<p><b>New page</b></p><div>'''Unreleased structure'''<br />
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The entry 8htw is ON HOLD until Paper Publication<br />
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Authors: <br />
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Description: <br />
[[Category: Unreleased Structures]]</div>
OCA