OCA at 13:09, 1 November 2023

2023-11-01T13:09:46Z

←Older revision		Revision as of 13:09, 1 November 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8jov is ~~ON HOLD until Paper~~ Publication	+	==Portal-tail complex of phage GP4==
		+	<StructureSection load='8jov' size='340' side='right'caption='[[8jov]], [[Resolution\|resolution]] 3.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8jov]] is a 60 chain structure with sequence from [https://en.wikipedia.org/wiki/Ralstonia_phage_GP4 Ralstonia phage GP4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JOV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JOV FirstGlance]. <br>
		+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.8Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jov OCA], [https://pdbe.org/8jov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jov RCSB], [https://www.ebi.ac.uk/pdbsum/8jov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jov ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A345GTT8_9CAUD A0A345GTT8_9CAUD]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacteriophage tail fibers (or called tail spikes) play a critical role in the early stage of infection by binding to the bacterial surface. Podophages with known structures usually possess one or two types of fibers. Here, we resolved an asymmetric structure of the podophage GP4 to near-atomic resolution by cryo-EM. Our structure revealed a symmetry-mismatch relationship between the components of the GP4 tail with previously unseen topologies. In detail, two dodecameric adaptors (adaptors I and II), a hexameric nozzle, and a tail needle form a conserved tail body connected to a dodecameric portal occupying a unique vertex of the icosahedral head. However, five chain-like extended fibers (fiber I) and five tulip-like short fibers (fiber II) are anchored to a 15-fold symmetric fiber-tail adaptor, encircling the adaptor I, and six bamboo-like trimeric fibers (fiber III) are connected to the nozzle. Five fibers I, each composed of five dimers of the protein gp80 linked by an elongated rope protein, are attached to the five edges of the tail vertex of the icosahedral head. In this study, we identified a new structure of the podophage with three types of tail fibers, and such phages with different types of fibers may have a broad host range and/or infect host cells with considerably high efficiency, providing evolutionary advantages in harsh environments.

-	~~Authors: Liu, H~~., ~~Chen~~, W.	+	Asymmetric Structure of Podophage GP4 Reveals a Novel Architecture of Three Types of Tail Fibers.,Zheng J, Chen W, Xiao H, Yang F, Song J, Cheng L, Liu H J Mol Biol. 2023 Oct 15;435(20):168258. doi: 10.1016/j.jmb.2023.168258. Epub 2023 , Sep 1. PMID:37660940<ref>PMID:37660940</ref>

-	~~Description: Portal-tail complex~~ of ~~phage GP4~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: Chen, W]]	+	<div class="pdbe-citations 8jov" style="background-color:#fffaf0;"></div>
-	[[Category: Liu, H]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Ralstonia phage GP4]]
		+	[[Category: Chen W]]
		+	[[Category: Liu H]]

OCA at 03:56, 12 July 2023

2023-07-12T03:56:25Z

←Older revision		Revision as of 03:56, 12 July 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8jov is ON HOLD	+	The entry 8jov is ON HOLD until Paper Publication

	Authors: Liu, H., Chen, W.		Authors: Liu, H., Chen, W.

OCA at 08:05, 21 June 2023

2023-06-21T08:05:05Z

←Older revision		Revision as of 08:05, 21 June 2023
Line 3:		Line 3:
	The entry 8jov is ON HOLD		The entry 8jov is ON HOLD

-	Authors: ~~Hongrong~~, L., ~~Wenyuan~~, C.	+	Authors: Liu, H., Chen, W.

-	Description: ~~portal~~-tail complex of phage GP4	+	Description: Portal-tail complex of phage GP4
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Hongrong~~, L]]	+	[[Category: Chen, W]]
-	[[Category: ~~Wenyuan~~, C]]	+	[[Category: Liu, H]]

OCA: Protected "8jov" [edit=sysop:move=sysop]

2023-06-14T06:31:34Z

Protected "8jov" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:31, 14 June 2023

OCA: New page: '''Unreleased structure''' The entry 8jov is ON HOLD Authors: Hongrong, L., Wenyuan, C. Description: portal-tail complex of phage GP4 Category: Unreleased Structures [[Category: Ho...

2023-06-14T06:31:33Z

New page: '''Unreleased structure''' The entry 8jov is ON HOLD Authors: Hongrong, L., Wenyuan, C. Description: portal-tail complex of phage GP4 Category: Unreleased Structures [[Category: Ho...

New page

'''Unreleased structure'''

The entry 8jov is ON HOLD

Authors: Hongrong, L., Wenyuan, C.

Description: portal-tail complex of phage GP4
[[Category: Unreleased Structures]]
[[Category: Hongrong, L]]
[[Category: Wenyuan, C]]

8jov - Revision history

OCA at 13:09, 1 November 2023

OCA at 03:56, 12 July 2023

OCA at 08:05, 21 June 2023

OCA: Protected "8jov" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8jov is ON HOLD Authors: Hongrong, L., Wenyuan, C. Description: portal-tail complex of phage GP4 Category: Unreleased Structures [[Category: Ho...