OCA at 10:03, 20 December 2023

2023-12-20T10:03:36Z

←Older revision		Revision as of 10:03, 20 December 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8k9r is ~~ON HOLD until Paper Publication~~	+	==Cryo EM structure of the products-bound PGAP1(Bst1)-H443N from Chaetomium thermophilum==
-		+	<StructureSection load='8k9r' size='340' side='right'caption='[[8k9r]], [[Resolution\|resolution]] 2.68Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8k9r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Psychromonas_sp._B3M02 Psychromonas sp. B3M02] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K9R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K9R FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.68Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=05E:2-azanylethyl+[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl]+hydrogen+phosphate'>05E</scene>, <scene name='pdbligand=80Y:2-azanylethyl+[(2R,3S,4S,5S,6S)-3,4,5,6-tetrakis(oxidanyl)oxan-2-yl]methyl+hydrogen+phosphate'>80Y</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=L9H:[(2~{R})-1-octadecoxy-3-[oxidanyl-[(2~{R},3~{R},5~{S},6~{R})-2,3,4,5,6-pentakis(oxidanyl)cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl]+octadecanoate'>L9H</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=PA1:2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSE'>PA1</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k9r OCA], [https://pdbe.org/8k9r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k9r RCSB], [https://www.ebi.ac.uk/pdbsum/8k9r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k9r ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]]
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Psychromonas sp. B3M02]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Hong J]]
		+	[[Category: Li D]]
		+	[[Category: Li T]]
		+	[[Category: Qu Q]]

OCA at 04:18, 6 September 2023

2023-09-06T04:18:51Z

←Older revision		Revision as of 04:18, 6 September 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8k9r is ON HOLD	+	The entry 8k9r is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 04:35, 23 August 2023

2023-08-23T04:35:32Z

←Older revision		Revision as of 04:35, 23 August 2023
Line 3:		Line 3:
	The entry 8k9r is ON HOLD		The entry 8k9r is ON HOLD

-	Authors: ~~Li, T., Hong, J., Qu, Q., Li, D.~~	+	Authors:

-	Description: ~~Cryo EM structure of the products-bound PGAP1(Bst1)-H443N from Chaetomium thermophilum~~	+	Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Li, D]]
-	[[Category: Hong, J]]
-	[[Category: Li, T]]
-	[[Category: Qu, Q]]

OCA: Protected "8k9r" [edit=sysop:move=sysop]

2023-08-09T03:57:33Z

Protected "8k9r" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:57, 9 August 2023

OCA: New page: '''Unreleased structure''' The entry 8k9r is ON HOLD Authors: Li, T., Hong, J., Qu, Q., Li, D. Description: Cryo EM structure of the products-bound PGAP1(Bst1)-H443N from Chaetomium th...

2023-08-09T03:57:32Z

New page: '''Unreleased structure''' The entry 8k9r is ON HOLD Authors: Li, T., Hong, J., Qu, Q., Li, D. Description: Cryo EM structure of the products-bound PGAP1(Bst1)-H443N from Chaetomium th...

New page

'''Unreleased structure'''

The entry 8k9r is ON HOLD

Authors: Li, T., Hong, J., Qu, Q., Li, D.

Description: Cryo EM structure of the products-bound PGAP1(Bst1)-H443N from Chaetomium thermophilum
[[Category: Unreleased Structures]]
[[Category: Li, D]]
[[Category: Hong, J]]
[[Category: Li, T]]
[[Category: Qu, Q]]

8k9r - Revision history

OCA at 10:03, 20 December 2023

OCA at 04:18, 6 September 2023

OCA at 04:35, 23 August 2023

OCA: Protected "8k9r" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8k9r is ON HOLD Authors: Li, T., Hong, J., Qu, Q., Li, D. Description: Cryo EM structure of the products-bound PGAP1(Bst1)-H443N from Chaetomium th...