OCA at 12:07, 6 March 2024

2024-03-06T12:07:17Z

←Older revision		Revision as of 12:07, 6 March 2024
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-	'''Unreleased structure'''

-	~~The entry~~ 8pok is ~~ON HOLD until 2025~~-07-05	+	==Cryo-EM structure of cell-free synthesized human histamine H2 receptor coupled to heterotrimeric Gs protein in lipid environment==
-		+	<StructureSection load='8pok' size='340' side='right'caption='[[8pok]], [[Resolution\|resolution]] 3.40Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8pok]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8POK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8POK FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.4Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HSM:HISTAMINE'>HSM</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pok OCA], [https://pdbe.org/8pok PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pok RCSB], [https://www.ebi.ac.uk/pdbsum/8pok PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pok ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/HRH2_HUMAN HRH2_HUMAN] The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Homo sapiens]]
		+	[[Category: Lama glama]]
		+	[[Category: Large Structures]]
		+	[[Category: Bernhard F]]
		+	[[Category: Doetsch V]]
		+	[[Category: Hilger D]]
		+	[[Category: Januliene D]]
		+	[[Category: Koeck Z]]
		+	[[Category: Kolb P]]
		+	[[Category: Moeller A]]
		+	[[Category: Parey K]]
		+	[[Category: Persechino M]]
		+	[[Category: Pockes S]]
		+	[[Category: Schihada H]]
		+	[[Category: Schnelle K]]
		+	[[Category: Umbach S]]

OCA at 04:41, 23 August 2023

2023-08-23T04:41:02Z

←Older revision		Revision as of 04:41, 23 August 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8pok is ON HOLD	+	The entry 8pok is ON HOLD until 2025-07-05

	Authors:		Authors:

OCA at 10:55, 26 July 2023

2023-07-26T10:55:25Z

←Older revision		Revision as of 10:55, 26 July 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8pok is ON HOLD ~~until sometime in the future~~	+	The entry 8pok is ON HOLD

	Authors:		Authors:

OCA at 04:52, 19 July 2023

2023-07-19T04:52:09Z

←Older revision		Revision as of 04:52, 19 July 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8pok is ON HOLD	+	The entry 8pok is ON HOLD until sometime in the future

	Authors:		Authors:

OCA: Protected "8pok" [edit=sysop:move=sysop]

2023-07-12T04:25:31Z

Protected "8pok" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:25, 12 July 2023

OCA: New page: '''Unreleased structure''' The entry 8pok is ON HOLD Authors: Description: Category: Unreleased Structures

2023-07-12T04:25:29Z

New page: '''Unreleased structure''' The entry 8pok is ON HOLD Authors: Description: Category: Unreleased Structures

New page