OCA at 12:04, 8 November 2023

2023-11-08T12:04:42Z

←Older revision		Revision as of 12:04, 8 November 2023
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-	'''Unreleased structure'''

-	~~The entry~~ 8qhi is ~~ON HOLD~~	+	==NMR solution structure of the golden kiwi fruit allergen Act c 8.0101==
		+	<StructureSection load='8qhi' size='340' side='right'caption='[[8qhi]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[8qhi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinidia_deliciosa Actinidia deliciosa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QHI FirstGlance]. <br>
		+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qhi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qhi OCA], [https://pdbe.org/8qhi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qhi RCSB], [https://www.ebi.ac.uk/pdbsum/8qhi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qhi ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A2R6PW87_ACTCC A0A2R6PW87_ACTCC]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Kiwifruits have become one of the most common food sources triggering allergic reactions. In patients suffering from birch pollen related food allergy, reactions result from initial sensitization to the birch (Betula verrucosa) pollen allergen Bet v 1, followed by immunological cross-reactivity to structurally homologous proteins in kiwifruit. Clinical symptoms range from scratching and itching of the oral cavity to more severe immunological reactions such as rhino conjunctivitis. In this work we assigned backbone and side chain (1)H, (13)C and (15)N chemical shifts of the 17 kDa PR-10 allergens Act c 8.0101 and Act d 8.0101 from golden (Actinidia chinesis) and green (Actinidia deliciosa) kiwifruit by solution NMR spectroscopy. The chemical shift data confirm the characteristic Bet v 1 fold for both proteins, consisting of a seven-stranded antiparallel beta-sheet interrupted by two short alpha-helices, along with a long C-terminal alpha-helix. Our data provide the basis for determining the three-dimensional solution structures of these proteins and characterizing their immunological cross-reactivity on a structural basis.

-	~~Authors: Zeindl~~, R., Tollinger, M.	+	NMR resonance assignments of the PR-10 allergens Act c 8 and Act d 8 from golden and green kiwifruit.,Zeindl R, Tollinger M Biomol NMR Assign. 2021 Oct;15(2):367-371. doi: 10.1007/s12104-021-10031-w. Epub , 2021 Jun 9. PMID:34106433<ref>PMID:34106433</ref>

-	~~Description: NMR solution structure~~ of the ~~golden kiwi fruit allergen Act c 8~~.~~0101~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: ~~Zeindl, R~~]]	+	<div class="pdbe-citations 8qhi" style="background-color:#fffaf0;"></div>
-	[[Category: Tollinger, M]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Actinidia deliciosa]]
		+	[[Category: Large Structures]]
		+	[[Category: Tollinger M]]
		+	[[Category: Zeindl R]]

OCA: Protected "8qhi" [edit=sysop:move=sysop]

2023-09-20T12:17:26Z

Protected "8qhi" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:17, 20 September 2023

OCA: New page: '''Unreleased structure''' The entry 8qhi is ON HOLD Authors: Zeindl, R., Tollinger, M. Description: NMR solution structure of the golden kiwi fruit allergen Act c 8.0101 [[Category: U...

2023-09-20T12:17:25Z

New page: '''Unreleased structure''' The entry 8qhi is ON HOLD Authors: Zeindl, R., Tollinger, M. Description: NMR solution structure of the golden kiwi fruit allergen Act c 8.0101 [[Category: U...

New page

'''Unreleased structure'''

The entry 8qhi is ON HOLD

Authors: Zeindl, R., Tollinger, M.

Description: NMR solution structure of the golden kiwi fruit allergen Act c 8.0101
[[Category: Unreleased Structures]]
[[Category: Zeindl, R]]
[[Category: Tollinger, M]]

8qhi - Revision history

OCA at 12:04, 8 November 2023

OCA: Protected "8qhi" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 8qhi is ON HOLD Authors: Zeindl, R., Tollinger, M. Description: NMR solution structure of the golden kiwi fruit allergen Act c 8.0101 [[Category: U...