8wat - Revision history

OCA at 08:07, 6 December 2023

2023-12-06T08:07:36Z

←Older revision		Revision as of 08:07, 6 December 2023
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 8wat is ~~ON HOLD until Paper Publication~~	+	==De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt downstream of TSS==
-		+	<StructureSection load='8wat' size='340' side='right'caption='[[8wat]], [[Resolution\|resolution]] 2.82Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[8wat]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Amanita_phalloides Amanita phalloides], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WAT FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.82Å</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=G2L:3-O-METHYOXYETHYL-GUANOSINE-5-MONOPHOSPHATE'>G2L</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene>, <scene name='pdbligand=ILX:4,5-DIHYDROXYISOLEUCINE'>ILX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRD_000201:Alpha-Amanitin'>PRD_000201</scene>, <scene name='pdbligand=TRX:6-HYDROXYTRYPTOPHAN'>TRX</scene>, <scene name='pdbligand=W0F:[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+phosphono+hydrogen+phosphate'>W0F</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wat OCA], [https://pdbe.org/8wat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wat RCSB], [https://www.ebi.ac.uk/pdbsum/8wat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wat ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/AAMAT_AMAPH AAMAT_AMAPH] Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters (PubMed:4865716, PubMed:363352, PubMed:7642577, PubMed:8702941).<ref>PMID:363352</ref> <ref>PMID:4865716</ref> <ref>PMID:7642577</ref> <ref>PMID:8702941</ref> <ref>PMID:24613547</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Amanita phalloides]]
		+	[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
		+	[[Category: Sus scrofa]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Chen X]]
		+	[[Category: Li W]]
		+	[[Category: Liu W]]
		+	[[Category: Qu X]]
		+	[[Category: Ren Y]]
		+	[[Category: Wang Q]]
		+	[[Category: Wang X]]
		+	[[Category: Xu Y]]

OCA at 05:20, 27 September 2023

2023-09-27T05:20:34Z

←Older revision		Revision as of 05:20, 27 September 2023
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 8wat is ON HOLD	+	The entry 8wat is ON HOLD until Paper Publication

-	Authors: ~~Chen, X., Liu, W., Wang, Q., Wang, X., Ren, Y., Qu, X., Li, W., Xu, Y.~~	+	Authors:

-	Description: ~~De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt downstream of TSS~~	+	Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Qu, X]]
-	[[Category: Liu, W]]
-	[[Category: Chen, X]]
-	[[Category: Ren, Y]]
-	[[Category: Li, W]]
-	[[Category: Xu, Y]]
-	[[Category: Wang, Q]]
-	[[Category: Wang, X]]

OCA: Protected "8wat" [edit=sysop:move=sysop]

2023-09-20T13:00:38Z

Protected "8wat" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:00, 20 September 2023

OCA: New page: '''Unreleased structure''' The entry 8wat is ON HOLD Authors: Chen, X., Liu, W., Wang, Q., Wang, X., Ren, Y., Qu, X., Li, W., Xu, Y. Description: De novo transcribing complex 10 (TC10)...

2023-09-20T13:00:36Z

New page: '''Unreleased structure''' The entry 8wat is ON HOLD Authors: Chen, X., Liu, W., Wang, Q., Wang, X., Ren, Y., Qu, X., Li, W., Xu, Y. Description: De novo transcribing complex 10 (TC10)...

New page

'''Unreleased structure'''

The entry 8wat is ON HOLD

Authors: Chen, X., Liu, W., Wang, Q., Wang, X., Ren, Y., Qu, X., Li, W., Xu, Y.

Description: De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt downstream of TSS
[[Category: Unreleased Structures]]
[[Category: Qu, X]]
[[Category: Liu, W]]
[[Category: Chen, X]]
[[Category: Ren, Y]]
[[Category: Li, W]]
[[Category: Xu, Y]]
[[Category: Wang, Q]]
[[Category: Wang, X]]