Aripiprazole - Revision history

http://52.214.119.220/wiki/index.php?action=history&feed=atom&title=Aripiprazole Aripiprazole - Revision history 2026-04-12T02:57:43Z Revision history for this page on the wiki MediaWiki 1.11.2 http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=4020316&oldid=prev Michal Harel at 11:34, 21 January 2024 2024-01-21T11:34:04Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 11:34, 21 January 2024</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><seqtool/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><seqtool/></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='<del style="color: red; font-weight: bold; text-decoration: none;">Caption for this structure</del>' scene='95/958562/Cv/1'></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='<ins style="color: red; font-weight: bold; text-decoration: none;">Aripiprazole</ins>' scene='95/958562/Cv/1'></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> </table>

Michal Harel http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=3738962&oldid=prev Alexander Berchansky at 13:53, 23 March 2023 2023-03-23T13:53:45Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 13:53, 23 March 2023</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 3:</td> <td colspan="2" class="diff-lineno">Line 3:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>G-protein coupled receptor for 5-hydroxytryptamine (serotonin) <ref name='w'>PMID: 1330647</ref><ref name='Guo'>PMID: 19057895</ref><ref name='Q'>PMID: 18703043</ref>. Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)<ref name='e'>PMID: 28129538</ref>. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors<ref name='e'>PMID: 28129538</ref>. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways<ref name='e'>PMID: 28129538</ref>. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores <del style="color: red; font-weight: bold; text-decoration: none;">(</del><ref name='Q'>PMID: 18703043</ref>, <ref name='e'>PMID: 28129538</ref><del style="color: red; font-weight: bold; text-decoration: none;">)</del>. Affects neural activity, perception, cognition and mood <ref name='Q1'>PMID: 18297054</ref>. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>G-protein coupled receptor for 5-hydroxytryptamine (serotonin) <ref name='w'>PMID: 1330647</ref><ref name='Guo'>PMID: 19057895</ref><ref name='Q'>PMID: 18703043</ref>. Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)<ref name='e'>PMID: 28129538</ref>. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors<ref name='e'>PMID: 28129538</ref>. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways<ref name='e'>PMID: 28129538</ref>. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores<ref name='Q'>PMID: 18703043</ref>, <ref name='e'>PMID: 28129538</ref>. Affects neural activity, perception, cognition and mood <ref name='Q1'>PMID: 18297054</ref>. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td></tr> </table>

Alexander Berchansky http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=3738961&oldid=prev Alexander Berchansky at 13:53, 23 March 2023 2023-03-23T13:53:09Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 13:53, 23 March 2023</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 3:</td> <td colspan="2" class="diff-lineno">Line 3:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>G-protein coupled receptor for 5-hydroxytryptamine (serotonin) <ref name='w'>PMID: 1330647</ref><ref name='Guo'>PMID: 19057895</ref><ref name='Q'>PMID: 18703043</ref>. Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)<ref name='e'>PMID: 28129538</ref>. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors<ref name='e'>PMID: 28129538</ref>. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways<ref name='e'>PMID: 28129538</ref>. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (<ref name='Q'>PMID: 18703043</ref>, <ref name='e'>PMID: 28129538</ref>). Affects neural activity, perception, cognition and mood <del style="color: red; font-weight: bold; text-decoration: none;">(PubMed</del>:18297054<del style="color: red; font-weight: bold; text-decoration: none;">)</del>. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>G-protein coupled receptor for 5-hydroxytryptamine (serotonin) <ref name='w'>PMID: 1330647</ref><ref name='Guo'>PMID: 19057895</ref><ref name='Q'>PMID: 18703043</ref>. Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)<ref name='e'>PMID: 28129538</ref>. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors<ref name='e'>PMID: 28129538</ref>. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways<ref name='e'>PMID: 28129538</ref>. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (<ref name='Q'>PMID: 18703043</ref>, <ref name='e'>PMID: 28129538</ref>). Affects neural activity, perception, cognition and mood <ins style="color: red; font-weight: bold; text-decoration: none;"><ref name='Q1'>PMID</ins>: 18297054<ins style="color: red; font-weight: bold; text-decoration: none;"></ref></ins>. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td></tr> </table>

Alexander Berchansky http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=3738960&oldid=prev Alexander Berchansky at 13:51, 23 March 2023 2023-03-23T13:51:40Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 13:51, 23 March 2023</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 3:</td> <td colspan="2" class="diff-lineno">Line 3:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>G-protein coupled receptor for 5-hydroxytryptamine (serotonin) <ref name='w'>PMID: 1330647</ref><ref name='Guo'>PMID: 19057895</ref><ref name='Q'>PMID: 18703043</ref>. Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) <del style="color: red; font-weight: bold; text-decoration: none;">(PubMed</del>:28129538<del style="color: red; font-weight: bold; text-decoration: none;">)</del>. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors <del style="color: red; font-weight: bold; text-decoration: none;">(PubMed</del>:28129538<del style="color: red; font-weight: bold; text-decoration: none;">)</del>. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways <del style="color: red; font-weight: bold; text-decoration: none;">(PubMed</del>:28129538<del style="color: red; font-weight: bold; text-decoration: none;">)</del>. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (<del style="color: red; font-weight: bold; text-decoration: none;">PubMed</del>:18703043, <del style="color: red; font-weight: bold; text-decoration: none;">PubMed</del>:28129538). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>G-protein coupled receptor for 5-hydroxytryptamine (serotonin) <ref name='w'>PMID: 1330647</ref><ref name='Guo'>PMID: 19057895</ref><ref name='Q'>PMID: 18703043</ref>. Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)<ins style="color: red; font-weight: bold; text-decoration: none;"><ref name='e'>PMID</ins>: 28129538<ins style="color: red; font-weight: bold; text-decoration: none;"></ref></ins>. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors<ins style="color: red; font-weight: bold; text-decoration: none;"><ref name='e'>PMID</ins>: 28129538<ins style="color: red; font-weight: bold; text-decoration: none;"></ref></ins>. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways<ins style="color: red; font-weight: bold; text-decoration: none;"><ref name='e'>PMID</ins>: 28129538<ins style="color: red; font-weight: bold; text-decoration: none;"></ref></ins>. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (<ins style="color: red; font-weight: bold; text-decoration: none;"><ref name='Q'>PMID</ins>: 18703043<ins style="color: red; font-weight: bold; text-decoration: none;"></ref></ins>, <ins style="color: red; font-weight: bold; text-decoration: none;"><ref name='e'>PMID</ins>: 28129538<ins style="color: red; font-weight: bold; text-decoration: none;"></ref></ins>). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td></tr> </table>

Alexander Berchansky http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=3738958&oldid=prev Alexander Berchansky at 13:48, 23 March 2023 2023-03-23T13:48:44Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 13:48, 23 March 2023</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 3:</td> <td colspan="2" class="diff-lineno">Line 3:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>G-protein coupled receptor for 5-hydroxytryptamine (serotonin) <del style="color: red; font-weight: bold; text-decoration: none;">(PubMed</del>:1330647<del style="color: red; font-weight: bold; text-decoration: none;">, PubMed:18703043, PubMed</del>:19057895<del style="color: red; font-weight: bold; text-decoration: none;">)</del>. Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (PubMed:18703043, PubMed:28129538). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>G-protein coupled receptor for 5-hydroxytryptamine (serotonin) <ins style="color: red; font-weight: bold; text-decoration: none;"><ref name='w'>PMID</ins>: 1330647<ins style="color: red; font-weight: bold; text-decoration: none;"></ref><ref name='Guo'>PMID</ins>: 19057895<ins style="color: red; font-weight: bold; text-decoration: none;"></ref><ref name='Q'>PMID: 18703043</ref></ins>. Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (PubMed:18703043, PubMed:28129538). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td></tr> </table>

Alexander Berchansky http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=3738949&oldid=prev Alexander Berchansky at 10:42, 23 March 2023 2023-03-23T10:42:05Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 10:42, 23 March 2023</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 2:</td> <td colspan="2" class="diff-lineno">Line 2:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='95/958562/Cv/1'></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='95/958562/Cv/1'></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (PubMed:18703043, PubMed:28129538). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td></tr> </table>

Alexander Berchansky http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=3738948&oldid=prev Alexander Berchansky at 10:38, 23 March 2023 2023-03-23T10:38:58Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 10:38, 23 March 2023</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 4:</td> <td colspan="2" class="diff-lineno">Line 4:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/4'>Aripiprazole binding site</scene>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td></tr> </table>

Alexander Berchansky http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=3738926&oldid=prev Alexander Berchansky at 13:21, 22 March 2023 2023-03-22T13:21:58Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 13:21, 22 March 2023</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><seqtool/></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='95/958562/Cv/1'></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='95/958562/Cv/1'></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td></tr> </table>

Alexander Berchansky http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=3738925&oldid=prev Alexander Berchansky at 13:19, 22 March 2023 2023-03-22T13:19:56Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 13:19, 22 March 2023</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='95/958562/Cv/1'></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='95/958562/Cv/1'></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole].</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><scene name='95/958562/Cv/2'>Crystal structure of 5-HT2AR in complex with aripiprazole</scene> ([[7voe]]).</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td></tr> </table>

Alexander Berchansky http://52.214.119.220/wiki/index.php?title=Aripiprazole&diff=3738924&oldid=prev Alexander Berchansky at 10:57, 22 March 2023 2023-03-22T10:57:30Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 10:57, 22 March 2023</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='95/958562/Cv/1'></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='95/958562/Cv/1'></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Aripiprazole, sold under the brand names Abilify and Aristada among others, is an atypical antipsychotic<ins style="color: red; font-weight: bold; text-decoration: none;">. It is primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders and irritability associated with autism. See also [https://en.wikipedia.org/wiki/Aripiprazole]</ins>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td></tr> </table>

Alexander Berchansky