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		<id>http://52.214.119.220/wiki/index.php?action=history&amp;feed=atom&amp;title=Coatomer</id>
		<title>Coatomer - Revision history</title>
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		<updated>2026-04-14T05:26:58Z</updated>
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	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122519&amp;oldid=prev</id>
		<title>Alexander Berchansky at 08:41, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122519&amp;oldid=prev"/>
				<updated>2024-04-08T08:41:46Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 08:41, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 4:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 4:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;COPI function in the sorting and trafficking of proteins between sub cellular organelles &amp;lt;ref&amp;gt;PMID:34450031&amp;lt;/ref&amp;gt;. &lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt; &lt;/del&gt;COP1 induces membrane curvature during budding&amp;lt;ref&amp;gt;PMID:21893600&amp;lt;/ref&amp;gt;. Dilysine motifs on transmembrane proteins are recognised by COPI alpha and beta' subunits and packaged into COPI-coated vesicles for transport from Golgi to ER&amp;lt;ref&amp;gt;PMID:23481256&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;COPI function in the sorting and trafficking of proteins between sub cellular organelles &amp;lt;ref&amp;gt;PMID:34450031&amp;lt;/ref&amp;gt;. COP1 induces membrane curvature during budding&amp;lt;ref&amp;gt;PMID:21893600&amp;lt;/ref&amp;gt;. Dilysine motifs on transmembrane proteins are recognised by COPI alpha and beta' subunits and packaged into COPI-coated vesicles for transport from Golgi to ER&amp;lt;ref&amp;gt;PMID:23481256&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Disease ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Disease ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 12:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 12:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Structural highlights ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Structural highlights ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;The COPI/Arf-1 complex consists of subunit alpha, subunit beta, subunit beta', subunit gamma-1, subunit delta, subunit zeta-1 and protein Arf-1&amp;lt;ref&amp;gt;PMID:28621666&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;The &lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;scene name='10/1041515/Cv/3'&amp;gt;&lt;/ins&gt;COPI/Arf-1 complex&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;/scene&amp;gt; &lt;/ins&gt;consists of subunit alpha, subunit beta, subunit beta', subunit gamma-1, subunit delta, subunit zeta-1 and protein Arf-1&amp;lt;ref&amp;gt;PMID:28621666&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Coatomer 3D structures==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Coatomer 3D structures==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Alexander Berchansky</name></author>	</entry>

	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122518&amp;oldid=prev</id>
		<title>Alexander Berchansky at 08:19, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122518&amp;oldid=prev"/>
				<updated>2024-04-08T08:19:25Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 08:19, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Arf-1 (cyan) (PDB entry [[5nzu]])' scene='10/1041515/Cv/&lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;1&lt;/del&gt;'&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Arf-1 (cyan) (PDB entry [[5nzu]])' scene='10/1041515/Cv/&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;2&lt;/ins&gt;'&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:1898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  Protein ADP-ribosylation factor 1 (Arf-1) is part of the vesicle-coating complex&amp;lt;ref&amp;gt;PMID:9681627&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:1898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  Protein ADP-ribosylation factor 1 (Arf-1) is part of the vesicle-coating complex&amp;lt;ref&amp;gt;PMID:9681627&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Alexander Berchansky</name></author>	</entry>

	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122517&amp;oldid=prev</id>
		<title>Alexander Berchansky at 08:16, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122517&amp;oldid=prev"/>
				<updated>2024-04-08T08:16:45Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 08:16, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Arf-1 (cyan) (PDB entry [[5nzu]])' scene=&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Arf-1 (cyan) (PDB entry [[5nzu]])' scene=&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;'10/1041515/Cv/1'&lt;/ins&gt;&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:1898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  Protein ADP-ribosylation factor 1 (Arf-1) is part of the vesicle-coating complex&amp;lt;ref&amp;gt;PMID:9681627&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:1898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  Protein ADP-ribosylation factor 1 (Arf-1) is part of the vesicle-coating complex&amp;lt;ref&amp;gt;PMID:9681627&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Alexander Berchansky</name></author>	</entry>

	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122515&amp;oldid=prev</id>
		<title>Michal Harel at 07:48, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122515&amp;oldid=prev"/>
				<updated>2024-04-08T07:48:35Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 07:48, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 8:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 8:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Disease ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Disease ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;Mutations in COPI can result in osteoporosis, fractures and developmental delays.  Deficiency in COPI alpha subunit cause COPA syndrome&amp;lt;ref&amp;gt;PMID:&lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;3584149&lt;/del&gt;&amp;lt;/ref&amp;gt;.  &lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;Mutations in COPI can result in osteoporosis, fractures and developmental delays.  Deficiency in COPI alpha subunit cause COPA syndrome&amp;lt;ref&amp;gt;PMID:&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;30804679&lt;/ins&gt;&amp;lt;/ref&amp;gt;.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Structural highlights ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Structural highlights ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Michal Harel</name></author>	</entry>

	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122514&amp;oldid=prev</id>
		<title>Michal Harel at 07:45, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122514&amp;oldid=prev"/>
				<updated>2024-04-08T07:45:30Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
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				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 07:45, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Arf-1 (cyan) (PDB entry [[5nzu]])' scene=&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Arf-1 (cyan) (PDB entry [[5nzu]])' scene=&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:&lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;898986&lt;/del&gt;&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  Protein ADP-ribosylation factor 1 (Arf-1) is part of the vesicle-coating complex&amp;lt;ref&amp;gt;PMID:9681627&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;1898986&lt;/ins&gt;&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  Protein ADP-ribosylation factor 1 (Arf-1) is part of the vesicle-coating complex&amp;lt;ref&amp;gt;PMID:9681627&amp;lt;/ref&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Michal Harel</name></author>	</entry>

	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122513&amp;oldid=prev</id>
		<title>Michal Harel at 07:44, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122513&amp;oldid=prev"/>
				<updated>2024-04-08T07:44:39Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
			&lt;col class='diff-marker' /&gt;
			&lt;col class='diff-content' /&gt;
			&lt;col class='diff-marker' /&gt;
			&lt;col class='diff-content' /&gt;
			&lt;tr&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 07:44, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 9:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 9:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;Mutations in COPI can result in osteoporosis, fractures and developmental delays.  Deficiency in COPI alpha subunit cause COPA syndrome&amp;lt;ref&amp;gt;PMID:3584149&amp;lt;/ref&amp;gt;.  &lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;Mutations in COPI can result in osteoporosis, fractures and developmental delays.  Deficiency in COPI alpha subunit cause COPA syndrome&amp;lt;ref&amp;gt;PMID:3584149&amp;lt;/ref&amp;gt;.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Relevance ==&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Structural highlights ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Structural highlights ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Michal Harel</name></author>	</entry>

	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122512&amp;oldid=prev</id>
		<title>Michal Harel at 07:44, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122512&amp;oldid=prev"/>
				<updated>2024-04-08T07:44:04Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
			&lt;col class='diff-marker' /&gt;
			&lt;col class='diff-content' /&gt;
			&lt;col class='diff-marker' /&gt;
			&lt;col class='diff-content' /&gt;
			&lt;tr&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 07:44, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 14:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 14:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Structural highlights ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Structural highlights ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;This is a sample scene created with SAT to &amp;lt;scene name=&amp;quot;/12/3456/Sample&lt;/del&gt;/1&lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;&amp;quot;&amp;gt;color&amp;lt;/scene&amp;gt; by Group&lt;/del&gt;, and &lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;another to make &lt;/del&gt;&amp;lt;&lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;scene name=&amp;quot;/12/3456/Sample/2&amp;quot;&lt;/del&gt;&amp;gt;&lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;a transparent representation&lt;/del&gt;&amp;lt;/&lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;scene&lt;/del&gt;&amp;gt; &lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes&lt;/del&gt;.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;The COPI&lt;/ins&gt;/&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;Arf-&lt;/ins&gt;1 &lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;complex consists of subunit alpha, subunit beta&lt;/ins&gt;, &lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;subunit beta', subunit gamma-1, subunit delta, subunit zeta-1 &lt;/ins&gt;and &lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;protein Arf-1&lt;/ins&gt;&amp;lt;&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;ref&lt;/ins&gt;&amp;gt;&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;PMID:28621666&lt;/ins&gt;&amp;lt;/&lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;ref&lt;/ins&gt;&amp;gt;.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Coatomer 3D structures==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;==Coatomer 3D structures==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Michal Harel</name></author>	</entry>

	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122511&amp;oldid=prev</id>
		<title>Michal Harel at 07:38, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122511&amp;oldid=prev"/>
				<updated>2024-04-08T07:38:33Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
			&lt;col class='diff-marker' /&gt;
			&lt;col class='diff-content' /&gt;
			&lt;col class='diff-marker' /&gt;
			&lt;col class='diff-content' /&gt;
			&lt;tr&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 07:38, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein &lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;Art&lt;/del&gt;-1 (cyan) (PDB entry [[5nzu]])' scene=&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein &lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;Arf&lt;/ins&gt;-1 (cyan) (PDB entry [[5nzu]])' scene=&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  &lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  &lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;Protein ADP-ribosylation factor 1 (Arf-1) is part of the vesicle-coating complex&amp;lt;ref&amp;gt;PMID:9681627&amp;lt;/ref&amp;gt;.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Michal Harel</name></author>	</entry>

	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122510&amp;oldid=prev</id>
		<title>Michal Harel at 07:32, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122510&amp;oldid=prev"/>
				<updated>2024-04-08T07:32:52Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
			&lt;col class='diff-marker' /&gt;
			&lt;col class='diff-content' /&gt;
			&lt;col class='diff-marker' /&gt;
			&lt;col class='diff-content' /&gt;
			&lt;tr&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 07:32, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Art-1 (cyan) (PDB entry [[5nzu]])' scene=&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta prime (pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Art-1 (cyan) (PDB entry [[5nzu]])' scene=&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  &lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;COP1 induces membrane curvature during budding&amp;lt;ref&amp;gt;PMID:21893600&amp;lt;/ref&amp;gt;. &lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;nbsp;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;#160;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;COPI function in the sorting and trafficking of proteins between sub cellular organelles &amp;lt;ref&amp;gt;PMID:34450031&amp;lt;/ref&amp;gt;.  &lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;COPI function in the sorting and trafficking of proteins between sub cellular organelles &amp;lt;ref&amp;gt;PMID:34450031&amp;lt;/ref&amp;gt;.  &lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;COP1 induces membrane curvature during budding&amp;lt;ref&amp;gt;PMID:21893600&amp;lt;/ref&amp;gt;. Dilysine motifs on transmembrane proteins are recognised by COPI alpha and beta' subunits and packaged into COPI-coated vesicles for transport from Golgi to ER&amp;lt;ref&amp;gt;PMID:23481256&amp;lt;/ref&amp;gt;.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Disease ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Disease ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;Mutations in COPI can result in osteoporosis, fractures and developmental delays.  Deficiency in COPI alpha subunit cause COPA syndrome&amp;lt;ref&amp;gt;PMID:3584149&amp;lt;/ref&amp;gt;. &lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;Mutations in COPI can result in osteoporosis, fractures and developmental delays.  Deficiency in COPI alpha subunit cause COPA syndrome&amp;lt;ref&amp;gt;PMID:3584149&amp;lt;/ref&amp;gt;. &lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt; &lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Relevance ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Relevance ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Michal Harel</name></author>	</entry>

	<entry>
		<id>http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122509&amp;oldid=prev</id>
		<title>Michal Harel at 07:21, 8 April 2024</title>
		<link rel="alternate" type="text/html" href="http://52.214.119.220/wiki/index.php?title=Coatomer&amp;diff=4122509&amp;oldid=prev"/>
				<updated>2024-04-08T07:21:01Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;

			&lt;table style=&quot;background-color: white; color:black;&quot;&gt;
			&lt;col class='diff-marker' /&gt;
			&lt;col class='diff-content' /&gt;
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			&lt;tr&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;←Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black;&quot;&gt;Revision as of 07:21, 8 April 2024&lt;/td&gt;
			&lt;/tr&gt;
		&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;-&lt;/td&gt;&lt;td style=&quot;background: #ffa; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta&lt;del style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;' &lt;/del&gt;(pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Art-1 (cyan) (PDB entry [[5nzu]])' scene=&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;background: #cfc; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;&amp;lt;StructureSection load='5nzu' size='350' side='right' caption='Mouse COPI coat complex containing subunits alpha (grey), beta (green), beta &lt;ins style=&quot;color: red; font-weight: bold; text-decoration: none;&quot;&gt;prime &lt;/ins&gt;(pink), delta (yellow), gamma-1 (red), zeta-1 (aqua) and protein Art-1 (cyan) (PDB entry [[5nzu]])' scene=&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  COP1 induces membrane curvature during budding&amp;lt;ref&amp;gt;PMID:21893600&amp;lt;/ref&amp;gt;. &lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;'''Coatomers''' (COPI) are a set of vesicles' coating proteins &amp;lt;ref&amp;gt;PMID:898986&amp;lt;/ref&amp;gt;.  Coatomers contain several subunits which are named according to decreasing molecular weight as alpha, beta', gamma, delta, epsilon and zeta-1.  COP1 induces membrane curvature during budding&amp;lt;ref&amp;gt;PMID:21893600&amp;lt;/ref&amp;gt;. &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt; &lt;/td&gt;&lt;td style=&quot;background: #eee; color:black; font-size: smaller;&quot;&gt;&lt;div&gt;== Function ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Michal Harel</name></author>	</entry>

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