Elongation factor 3D structures - Revision history

Joel L. Sussman at 07:37, 16 February 2023

2023-02-16T07:37:20Z

←Older revision		Revision as of 07:37, 16 February 2023
Line 207:		Line 207:
	**[[4cxg]], [[4cxh]] - rEF in 40S ribosome – Cryo EM<BR />		**[[4cxg]], [[4cxh]] - rEF in 40S ribosome – Cryo EM<BR />
	**[[7ls1]], [[7ls2]] - mEF in 80S ribosome – Cryo EM<BR />		**[[7ls1]], [[7ls2]] - mEF in 80S ribosome – Cryo EM<BR />
-	**[[~~3j38~~]] - DmEF in 40S ribosome – Cryo EM<BR />	+	**[[4v6w]] - DmEF in 40S ribosome – Cryo EM<BR />
	**[[7osm]] - yEF in 80S ribosome<BR />		**[[7osm]] - yEF in 80S ribosome<BR />
	**[[5jup]], [[5jus]], [[5jut]], [[5juu]], [[6gq1]], [[7osa]] - yEF in 80S ribosome – Cryo EM<BR />		**[[5jup]], [[5jus]], [[5jut]], [[5juu]], [[6gq1]], [[7osa]] - yEF in 80S ribosome – Cryo EM<BR />

Michal Harel at 09:28, 14 February 2023

2023-02-14T09:28:54Z

(Difference between revisions)

Michal Harel at 09:15, 13 July 2021

2021-07-13T09:15:56Z

←Older revision		Revision as of 09:15, 13 July 2021
Line 154:		Line 154:
	**[[6s8z]] – EF – ''Corynebacterium glutamicum'' <br />		**[[6s8z]] – EF – ''Corynebacterium glutamicum'' <br />
	**[[5wxk]] – EF + EARP – ''Neisseria meningitidis''<br />		**[[5wxk]] – EF + EARP – ''Neisseria meningitidis''<br />
-

	*EF-Ts		*EF-Ts
Line 226:		Line 225:
	**[[6gmh]], [[6gml]] – hEF-Spt4 + EF-Spt5 + EF-Spt6 in transcription complex – Cryo EM<br />		**[[6gmh]], [[6gml]] – hEF-Spt4 + EF-Spt5 + EF-Spt6 in transcription complex – Cryo EM<br />
	**[[5oik]] – bEF-Spt4 + EF-Spt5 + RNA polymerase II <br />		**[[5oik]] – bEF-Spt4 + EF-Spt5 + RNA polymerase II <br />
		+	**[[7nky]] – yEF-Spt4 + EF-Spt5 + EF-Spt16 in RNA polymerase II elongation complex - CryoEM<br />
	**[[2exu]] – yEF-Spt4 residues 1-99 + EF-Spt5 residues 285-375<br />		**[[2exu]] – yEF-Spt4 residues 1-99 + EF-Spt5 residues 285-375<br />
	**[[4zn3]], [[4zn1]] – EF-Spt4 + EF-Spt5 – ''Methanocaldococcus jannaschii'' <br />		**[[4zn3]], [[4zn1]] – EF-Spt4 + EF-Spt5 – ''Methanocaldococcus jannaschii'' <br />
Line 249:		Line 249:
	**[[4z2m]] – hEF middle domain + histone H3.1 + histone H4<br />		**[[4z2m]] – hEF middle domain + histone H3.1 + histone H4<br />
	**[[6gme]] – hEF SH2 domain residues 1317-1334<br />		**[[6gme]] – hEF SH2 domain residues 1317-1334<br />
		+	**[[6ted]] – pEF in RNA polymerase II transcription complex - CryoEM<br />
	**[[3psf]], [[3psi]] – yEF core domain residues 235-1259<BR />		**[[3psf]], [[3psi]] – yEF core domain residues 235-1259<BR />
	**[[3psj]], [[3psk]] – yEF SH2 domain residues 1247-1451<BR />		**[[3psj]], [[3psk]] – yEF SH2 domain residues 1247-1451<BR />
Line 288:		Line 289:
	*Elongin BC complex		*Elongin BC complex

-	**[[1lqb]], [[1lm8]] – hEloBC + ~~von-Hippel Lindau disease tumor suppressor~~ + hypoxia inducible factor 1 α<br />	+	**[[1lqb]], [[1lm8]] – hEloBC + VHL + hypoxia inducible factor 1 α<br />
-	**[[6i7q]], [[6i7r]] – hEloBC + ~~von-Hippel Lindau disease tumor suppressor~~ + hypoxia inducible factor 2 α<br />	+	**[[6i7q]], [[6i7r]] – hEloBC + VHL + hypoxia inducible factor 2 α<br />
-	**[[3zrc]], [[3ztc]], [[3ztd]], [[3zun]], [[6fmi]], [[6fmj]], [[6fmk]], [[5nw2]], [[5nw1]], [[5nw0]], [[5nvz]], [[5nvy]], [[5nvx]], [[5nvw]], [[5nvv]], [[4w9l]], [[4w9k]], [[4w9j]], [[4w9i]], [[4w9h]], [[4w9g]], [[4w9f]], [[4w9e]], [[4w9d]], [[4w9c]], [[6gfy]] - hEloBC + ~~von-Hippel Lindau disease tumor suppressor~~ + inhibitor<br />	+	**[[3zrc]], [[3ztc]], [[3ztd]], [[3zun]], [[6fmi]], [[6fmj]], [[6fmk]], [[5nw2]], [[5nw1]], [[5nw0]], [[5nvz]], [[5nvy]], [[5nvx]], [[5nvw]], [[5nvv]], [[4w9l]], [[4w9k]], [[4w9j]], [[4w9i]], [[4w9h]], [[4w9g]], [[4w9f]], [[4w9e]], [[4w9d]], [[4w9c]], [[6gfy]] - hEloBC + VHL + inhibitor<br />
-	**[[5t35]], [[6sis]] - hEloBC + ~~von~~-~~Hippel Lindau disease tumor suppressor~~ + BRD4<br />	+	**[[5t35]], [[6sis]] - hEloBC + VHL + BRD4<br />
-	**[[4wqo]] - hEloBC + ~~von-Hippel Lindau disease tumor suppressor~~ + cullin-2 <br />	+	**[[7khh]] - hEloBC + VHL + BRD4 + inhibitor<br />
-	**[[6hr2]], [[6hay]], [[6hax]] - hEloBC + ~~von-Hippel Lindau disease tumor suppressor~~ + transcription activator <br />	+	**[[4wqo]] - hEloBC + VHL + cullin-2 <br />
-	**[[6gmr]], [[6gfx]], [[6bvb]] - hEloBC + ~~von-Hippel Lindau disease tumor suppressor~~ + hypoxia inducible factor peptide <br />	+	**[[6hr2]], [[6hay]], [[6hax]] - hEloBC + VHL + transcription activator <br />
		+	**[[6gmr]], [[6gfx]], [[6bvb]] - hEloBC + VHL + hypoxia inducible factor peptide <br />
	**[[5n4w]] - hEloBC + von-Hippel Lindau disease tumor suppressor + cullin-2 + RBX1<br />		**[[5n4w]] - hEloBC + von-Hippel Lindau disease tumor suppressor + cullin-2 + RBX1<br />
-	**[[3zrf]], [[5lli]], [[6gmx]], [[6gmq]], [[6gmn]], [[6gfz]] - hEloBC + ~~von~~-~~Hippel Lindau disease tumor suppressor~~<br />	+	**[[3zrf]], [[5lli]], [[6gmx]], [[6gmq]], [[6gmn]], [[6gfz]] - hEloBC + VHL<br />
		+	**[[6zhc]] - hEloBC + VHL + Bcl-2-like protein<br />
	**[[2c9w]], [[2izv]], [[2jz3]], [[5bo4]] – hEloBC + suppressor of cytokine signaling<br />		**[[2c9w]], [[2izv]], [[2jz3]], [[5bo4]] – hEloBC + suppressor of cytokine signaling<br />
	**[[6c5x]] – hEloBC + suppressor of cytokine signaling + Gp130 peptide<br />		**[[6c5x]] – hEloBC + suppressor of cytokine signaling + Gp130 peptide<br />
Line 305:		Line 308:
	**[[1vcb]] – hEloBC + VHL<br />		**[[1vcb]] – hEloBC + VHL<br />
	**[[6v9h]] – hEloBC + creatine kinase + ASB-9 – Cryo EM<br />		**[[6v9h]] – hEloBC + creatine kinase + ASB-9 – Cryo EM<br />
		+	**[[6r6h]], [[6r7f]], [[6r7h]], [[6r7i]], [[6r7n]] – hEloBC in signalosome – Cryo EM<br />
	**[[2fnj]] - mEloBC + GUSTAVUS		**[[2fnj]] - mEloBC + GUSTAVUS
	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 08:31, 13 July 2021

2021-07-13T08:31:23Z

←Older revision		Revision as of 08:31, 13 July 2021
Line 74:		Line 74:

	**[[3eq3]], [[3eq4]] – EcEF in 80S ribosome – Cryo EM<BR />		**[[3eq3]], [[3eq4]] – EcEF in 80S ribosome – Cryo EM<BR />
		+	**[[6wd2]], [[6wd3]], [[6wd4]], [[6wd5]], [[6wd6]], [[6wd7]], [[6wd8]], [[6wd9]], [[6wda]] – EcEF in 80S ribosome + GDP – Cryo EM<BR />
	**[[4v6l]], [[4v6k]], [[4v69]] - EcEF in 30S ribosome – Cryo EM<BR />		**[[4v6l]], [[4v6k]], [[4v69]] - EcEF in 30S ribosome – Cryo EM<BR />
	**[[1zc8]], [[3dwu]] – TtEF in 70S ribosome – Cryo EM<BR />		**[[1zc8]], [[3dwu]] – TtEF in 70S ribosome – Cryo EM<BR />
Line 131:		Line 132:
	**[[2p4v]] – EcEF-GreB<br />		**[[2p4v]] – EcEF-GreB<br />
	**[[1grj]] – EcEF-GreA<br />		**[[1grj]] – EcEF-GreA<br />
		+	**[[6ri7]], [[6rin]] – EcEF-GreB + transcriptase + DNA + RNA – Cryo EM<br />

	*EF-NusA		*EF-NusA
Line 174:		Line 176:
	**[[5o8w]] – yEF α+β <br />		**[[5o8w]] – yEF α+β <br />
	**[[1nhy]] – yEF γ N terminal<br />		**[[1nhy]] – yEF γ N terminal<br />
		+	**[[7csl]] – PhEF α+β <br />

	*EF-2		*EF-2
Line 183:		Line 186:
	**[[1n0u]], [[2e1r]], [[2npf]] – yEF + antifungal drug<BR />		**[[1n0u]], [[2e1r]], [[2npf]] – yEF + antifungal drug<BR />
	**[[1zm2]], [[1zm3]], [[1zm4]], [[1zm9]], [[3b78]], [[3b82]], [[3b8h]], [[2zit]] – yEF + exotoxin<BR />		**[[1zm2]], [[1zm3]], [[1zm4]], [[1zm9]], [[3b78]], [[3b82]], [[3b8h]], [[2zit]] – yEF + exotoxin<BR />
-	**[[2p8w]], [[2p8x]], [[3dny]] - yEF in 80S ribosome – Cryo EM<BR />	+	**[[2p8w]], [[2p8x]], [[3dny]], [[6gqb]], [[6gqv]] - yEF in 80S ribosome – Cryo EM<BR />
	**[[2p8y]], [[2p8z]] - yEF+ antifungal drug in 80S ribosome – Cryo EM<BR />		**[[2p8y]], [[2p8z]] - yEF+ antifungal drug in 80S ribosome – Cryo EM<BR />
	**[[5h7j]] - PhEF <BR />		**[[5h7j]] - PhEF <BR />
Line 190:		Line 193:
	**[[6u45]] – MnEF + GMPPCP – ''Methanoperedens nitroreducens'' <BR />		**[[6u45]] – MnEF + GMPPCP – ''Methanoperedens nitroreducens'' <BR />
	**[[6u43]], [[6u44]] – MnEF (mutant) + GMPPCP <BR />		**[[6u43]], [[6u44]] – MnEF (mutant) + GMPPCP <BR />
		+	**[[6q2d]] - EF + DPH2 – ''Methanobrevibacter smithii''<BR />

	*EF-3		*EF-3

Michal Harel at 10:27, 20 July 2020

2020-07-20T10:27:09Z

←Older revision		Revision as of 10:27, 20 July 2020
Line 16:		Line 16:
	**[[1b23]] - TaEF + Cys-tRNA<BR />		**[[1b23]] - TaEF + Cys-tRNA<BR />
	**[[3wxm]] – ApEF + plethora protein – ''Aeropyrum pernix''<br />		**[[3wxm]] – ApEF + plethora protein – ''Aeropyrum pernix''<br />
		+	**[[6ji2]] - ApEF + plethora protein + AP2<br />
	**[[4h9g]], [[4lbv]], [[4lbw]], [[4lby]], [[4lbz]], [[4lc0]] – TtEF – ''Thermus thermophilus''<br />		**[[4h9g]], [[4lbv]], [[4lbw]], [[4lby]], [[4lbz]], [[4lc0]] – TtEF – ''Thermus thermophilus''<br />
	**[[4j0q]] – PpEF – ''Pseudomonas putida''<br />		**[[4j0q]] – PpEF – ''Pseudomonas putida''<br />
	**[[5w75]] – EF – ''Thermotoga neapolitana''<br />		**[[5w75]] – EF – ''Thermotoga neapolitana''<br />
	**[[5tbf]] – EF domain 2-3– ''Vibrio cholerae''<br />		**[[5tbf]] – EF domain 2-3– ''Vibrio cholerae''<br />
		+	**[[6htw]], [[6i8r]] – EF – synthetic<br />

	*''EF-Tu complex with antibiotics''		*''EF-Tu complex with antibiotics''
Line 146:		Line 148:
	**[[1yby]] – EF – ''Clostridium thermocellum''<br />		**[[1yby]] – EF – ''Clostridium thermocellum''<br />
	**[[5j3b]] – AbEF <br />		**[[5j3b]] – AbEF <br />
		+	**[[6rji]] – SaEF <br />
		+	**[[6rk3]] – SaEF - NMR<br />
		+	**[[6s8z]] – EF – ''Corynebacterium glutamicum'' <br />
	**[[5wxk]] – EF + EARP – ''Neisseria meningitidis''<br />		**[[5wxk]] – EF + EARP – ''Neisseria meningitidis''<br />

Line 166:		Line 171:
	**[[5bmu]] – hEF ε-1 + Glu tRNA ligase <br />		**[[5bmu]] – hEF ε-1 + Glu tRNA ligase <br />
	**[[5y6l]] – hEF ε-1 (mutant) + MetRS + AspRS + Glu/Pro tRNA ligase + P38<br />		**[[5y6l]] – hEF ε-1 (mutant) + MetRS + AspRS + Glu/Pro tRNA ligase + P38<br />
-	**[[4c0s]] – rEF α-2 – rabbit<br />	+	**[[4c0s]], [[6ra9]] – rEF α-2 – rabbit<br />
	**[[5o8w]] – yEF α+β <br />		**[[5o8w]] – yEF α+β <br />
	**[[1nhy]] – yEF γ N terminal<br />		**[[1nhy]] – yEF γ N terminal<br />
Line 183:		Line 188:
	**[[5h7l]] - PhEF + L12<BR />		**[[5h7l]] - PhEF + L12<BR />
	**[[5h7k]] - PhEF + GDP<BR />		**[[5h7k]] - PhEF + GDP<BR />
		+	**[[6u45]] – MnEF + GMPPCP – ''Methanoperedens nitroreducens'' <BR />
		+	**[[6u43]], [[6u44]] – MnEF (mutant) + GMPPCP <BR />

	*EF-3		*EF-3
Line 213:		Line 220:

	**[[3h7h]] – hEF-Spt4 residues 2-117 + hEF-Spt5 residues 176-273<br />		**[[3h7h]] – hEF-Spt4 residues 2-117 + hEF-Spt5 residues 176-273<br />
		+	**[[6gmh]], [[6gml]] – hEF-Spt4 + EF-Spt5 + EF-Spt6 in transcription complex – Cryo EM<br />
	**[[5oik]] – bEF-Spt4 + EF-Spt5 + RNA polymerase II <br />		**[[5oik]] – bEF-Spt4 + EF-Spt5 + RNA polymerase II <br />
	**[[2exu]] – yEF-Spt4 residues 1-99 + EF-Spt5 residues 285-375<br />		**[[2exu]] – yEF-Spt4 residues 1-99 + EF-Spt5 residues 285-375<br />
	**[[4zn3]], [[4zn1]] – EF-Spt4 + EF-Spt5 – ''Methanocaldococcus jannaschii'' <br />		**[[4zn3]], [[4zn1]] – EF-Spt4 + EF-Spt5 – ''Methanocaldococcus jannaschii'' <br />
-	**[[5xon]], [[5xog]] – EF-Spt4 + EF-Spt5 + EF-Tfiis + RNA polymerase II - ''Komagataella phaffii'' - Cryo EM<br />	+	**[[5xon]], [[5xog]], [[6ir9]], [[6j4w]], [[6j4x]], [[6j4y]], [[6j4z]], [[6j50]], [[6j51]] – EF-Spt4 + EF-Spt5 + EF-Tfiis in RNA polymerase II elongation complex - ''Komagataella phaffii'' - Cryo EM<br />

	*EF-Spt5		*EF-Spt5
Line 236:		Line 244:
	**[[4z2n]] – hEF middle domain residues 644-930<br />		**[[4z2n]] – hEF middle domain residues 644-930<br />
	**[[4z2m]] – hEF middle domain + histone H3.1 + histone H4<br />		**[[4z2m]] – hEF middle domain + histone H3.1 + histone H4<br />
		+	**[[6gme]] – hEF SH2 domain residues 1317-1334<br />
	**[[3psf]], [[3psi]] – yEF core domain residues 235-1259<BR />		**[[3psf]], [[3psi]] – yEF core domain residues 235-1259<BR />
	**[[3psj]], [[3psk]] – yEF SH2 domain residues 1247-1451<BR />		**[[3psj]], [[3psk]] – yEF SH2 domain residues 1247-1451<BR />
Line 276:		Line 285:

	**[[1lqb]], [[1lm8]] – hEloBC + von-Hippel Lindau disease tumor suppressor + hypoxia inducible factor 1 α<br />		**[[1lqb]], [[1lm8]] – hEloBC + von-Hippel Lindau disease tumor suppressor + hypoxia inducible factor 1 α<br />
		+	**[[6i7q]], [[6i7r]] – hEloBC + von-Hippel Lindau disease tumor suppressor + hypoxia inducible factor 2 α<br />
	**[[3zrc]], [[3ztc]], [[3ztd]], [[3zun]], [[6fmi]], [[6fmj]], [[6fmk]], [[5nw2]], [[5nw1]], [[5nw0]], [[5nvz]], [[5nvy]], [[5nvx]], [[5nvw]], [[5nvv]], [[4w9l]], [[4w9k]], [[4w9j]], [[4w9i]], [[4w9h]], [[4w9g]], [[4w9f]], [[4w9e]], [[4w9d]], [[4w9c]], [[6gfy]] - hEloBC + von-Hippel Lindau disease tumor suppressor + inhibitor<br />		**[[3zrc]], [[3ztc]], [[3ztd]], [[3zun]], [[6fmi]], [[6fmj]], [[6fmk]], [[5nw2]], [[5nw1]], [[5nw0]], [[5nvz]], [[5nvy]], [[5nvx]], [[5nvw]], [[5nvv]], [[4w9l]], [[4w9k]], [[4w9j]], [[4w9i]], [[4w9h]], [[4w9g]], [[4w9f]], [[4w9e]], [[4w9d]], [[4w9c]], [[6gfy]] - hEloBC + von-Hippel Lindau disease tumor suppressor + inhibitor<br />
-	**[[5t35]] - hEloBC + von-Hippel Lindau disease tumor suppressor + BRD4<br />	+	**[[5t35]], [[6sis]] - hEloBC + von-Hippel Lindau disease tumor suppressor + BRD4<br />
	**[[4wqo]] - hEloBC + von-Hippel Lindau disease tumor suppressor + cullin-2 <br />		**[[4wqo]] - hEloBC + von-Hippel Lindau disease tumor suppressor + cullin-2 <br />
	**[[6hr2]], [[6hay]], [[6hax]] - hEloBC + von-Hippel Lindau disease tumor suppressor + transcription activator <br />		**[[6hr2]], [[6hay]], [[6hax]] - hEloBC + von-Hippel Lindau disease tumor suppressor + transcription activator <br />
Line 287:		Line 297:
	**[[6i5n]], [[6i5j]] – hEloBC + suppressor of cytokine signaling + growth hormone receptor peptide<br />		**[[6i5n]], [[6i5j]] – hEloBC + suppressor of cytokine signaling + growth hormone receptor peptide<br />
	**[[6i4x]] – hEloBC + suppressor of cytokine signaling + erythropoietin peptide<br />		**[[6i4x]] – hEloBC + suppressor of cytokine signaling + erythropoietin peptide<br />
-	**[[~~3dcg~~]] – hEloBC + virion infectivity factor<br />	+	**[[6p59]] - hEloBC + virion infectivity factor + CBF b<br />
	**[[3zkj]] - hEloBC + ankyrin rep<br />		**[[3zkj]] - hEloBC + ankyrin rep<br />
	**[[1vcb]] – hEloBC + VHL<br />		**[[1vcb]] – hEloBC + VHL<br />
		+	**[[6v9h]] – hEloBC + creatine kinase + ASB-9 – Cryo EM<br />
	**[[2fnj]] - mEloBC + GUSTAVUS		**[[2fnj]] - mEloBC + GUSTAVUS
	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 09:27, 20 July 2020

2020-07-20T09:27:56Z

←Older revision		Revision as of 09:27, 20 July 2020
Line 6:		Line 6:
	*EF-Tu		*EF-Tu

		+	**[[1ls2]] – yEF + Phe-tRNA – yeast – Cryo EM<BR />
	**[[1efm]], [[1efc]], [[1dg1]], [[2fx3]], [[1etu]], [[5mi3]] – EcEF – ''Escherichia coli''<BR />		**[[1efm]], [[1efc]], [[1dg1]], [[2fx3]], [[1etu]], [[5mi3]] – EcEF – ''Escherichia coli''<BR />
	**[[5mi8]], [[5mi9]] – EcEF (mutant) <br />		**[[5mi8]], [[5mi9]] – EcEF (mutant) <br />
Line 14:		Line 15:
	**[[1ttt]], [[1ob5]] – TaEF + Phe-tRNA + GDPNP - ''Thermus aquaticus''<BR />		**[[1ttt]], [[1ob5]] – TaEF + Phe-tRNA + GDPNP - ''Thermus aquaticus''<BR />
	**[[1b23]] - TaEF + Cys-tRNA<BR />		**[[1b23]] - TaEF + Cys-tRNA<BR />
-	**[[1ls2]] – yEF + Phe-tRNA – yeast – Cryo EM<BR />
	**[[3wxm]] – ApEF + plethora protein – ''Aeropyrum pernix''<br />		**[[3wxm]] – ApEF + plethora protein – ''Aeropyrum pernix''<br />
	**[[4h9g]], [[4lbv]], [[4lbw]], [[4lby]], [[4lbz]], [[4lc0]] – TtEF – ''Thermus thermophilus''<br />		**[[4h9g]], [[4lbv]], [[4lbw]], [[4lby]], [[4lbz]], [[4lc0]] – TtEF – ''Thermus thermophilus''<br />
Line 33:		Line 33:
	*''EF-Tu complex with nucleotide''		*''EF-Tu complex with nucleotide''

		+	**[[1d2e]] – bEF + GDP – bovine<BR />
	**[[6eze]] – EcEF + GDP derivative<BR />		**[[6eze]] – EcEF + GDP derivative<BR />
	**[[5opd]] – EcEF + GTP <BR />		**[[5opd]] – EcEF + GTP <BR />
Line 38:		Line 39:
	**[[1eft]] – TaEF + GNP – ''Thermus aquaticus''<BR />		**[[1eft]] – TaEF + GNP – ''Thermus aquaticus''<BR />
	**[[1tui]] – TaEF + GDP<BR />		**[[1tui]] – TaEF + GDP<BR />
-	**[[1d2e]] – bEF + GDP – bovine<BR />
	**[[1jny]], [[1skq]] – SsEF + GDP – ''Sulfolobus solfataricus''<br />		**[[1jny]], [[1skq]] – SsEF + GDP – ''Sulfolobus solfataricus''<br />
	**[[3wya]] – PhEF + GDP - ''Pyrococcus horikoshii''<br />		**[[3wya]] – PhEF + GDP - ''Pyrococcus horikoshii''<br />
Line 54:		Line 54:
	*''EF-Tu with EF-Ts''		*''EF-Tu with EF-Ts''

		+	**[[1xb2]] – bEF + EF-Ts - bovine<BR />
		+	**[[1f60]] – yEF + EF-Ts C terminal<BR />
		+	**[[1g7c]] - yEF + EF-Ts C terminal + GDPNP<BR />
		+	**[[1ije]], [[1ijf]] - yEF + EF-Ts C terminal + GDP<BR />
		+	**[[2b7b]] - yEF + EF-Ts C terminal (mutant) + GDP<BR />
		+	**[[2b7c]] - yEF + EF-Ts C terminal (mutant)<br />
	**[[1efu]], [[3agp]], [[3agq]], [[4pc1]] – EcEF + EcEF-Ts<BR />		**[[1efu]], [[3agp]], [[3agq]], [[4pc1]] – EcEF + EcEF-Ts<BR />
	**[[3avt]], [[3avu]] , [[3avv]], [[3avw]], [[3avx]], [[3avy]], [[3vnu]] , [[3vnv]], [[4fwt]] – EcEF + EcEF-Ts + RNA<br />		**[[3avt]], [[3avu]] , [[3avv]], [[3avw]], [[3avx]], [[3avy]], [[3vnu]] , [[3vnv]], [[4fwt]] – EcEF + EcEF-Ts + RNA<br />
Line 62:		Line 68:
	**[[4pc2]], [[4pc3]], [[4pc6]] – EcEF + EcEF-Ts + GDP derivative<br />		**[[4pc2]], [[4pc3]], [[4pc6]] – EcEF + EcEF-Ts + GDP derivative<br />
	**[[1aip]] - TtEF + TtEF-Ts - ''Thermus thermophilus''<BR />		**[[1aip]] - TtEF + TtEF-Ts - ''Thermus thermophilus''<BR />
-	**[[1xb2]] – bEF + EF-Ts - bovine<BR />
-	**[[1f60]] – yEF + EF-Ts C terminal<BR />
-	**[[1g7c]] - yEF + EF-Ts C terminal + GDPNP<BR />
-	**[[1ije]], [[1ijf]] - yEF + EF-Ts C terminal + GDP<BR />
-	**[[2b7b]] - yEF + EF-Ts C terminal (mutant) + GDP<BR />
-	**[[2b7c]] - yEF + EF-Ts C terminal (mutant)

	*''EF-Tu in the ribosome''		*''EF-Tu in the ribosome''
Line 80:		Line 80:
	**[[1tfi]] – hEF – human – NMR<BR />		**[[1tfi]] – hEF – human – NMR<BR />
	**[[3ndq]] - hEF domain II<BR />		**[[3ndq]] - hEF domain II<BR />
		+	**[[1wjt]] – mEF N terminal – mouse – NMR<BR />
	**[[1enw]] – yEF domain II – NMR<BR />		**[[1enw]] – yEF domain II – NMR<BR />
	**[[1eo0]] - yEF domain I – NMR<BR />		**[[1eo0]] - yEF domain I – NMR<BR />
-	**[[2xex]] – SaEF – ''Staphylococcus aureus''<BR />
	**[[1pqv]], [[1y1v]] – yEF + RNA polymerase II<BR />		**[[1pqv]], [[1y1v]] – yEF + RNA polymerase II<BR />
	**[[1y1y]], [[3gtm]] – yEF + RNA polymerase II + RNA<BR />		**[[1y1y]], [[3gtm]] – yEF + RNA polymerase II + RNA<BR />
-	**[[~~1wjt~~]] – ~~mEF N terminal~~ – ~~mouse – NMR~~<BR />	+	**[[2xex]] – SaEF – ''Staphylococcus aureus''<BR />
	**[[2m1h]] – EF PWWP domain – ''Trypanosoma brucei'' – NMR<br />		**[[2m1h]] – EF PWWP domain – ''Trypanosoma brucei'' – NMR<br />

Line 100:		Line 100:
	**[[1fnm]], [[2bm0]], [[2bm1]] – TtEF (mutant) <BR />		**[[1fnm]], [[2bm0]], [[2bm1]] – TtEF (mutant) <BR />
	**[[2bcw]] – TtEF + L11 + L7/L12 <br />		**[[2bcw]] – TtEF + L11 + L7/L12 <br />
-	**[[2xex]] – SaEF<BR />
-	**[[3zz0]], [[3zzt]], [[3zzu]] – SaEF (mutant) <BR />
	**[[2bv3]] - TtEF (mutant) + GTP analog<br />		**[[2bv3]] - TtEF (mutant) + GTP analog<br />
	**[[2j7k]] - TtEF (mutant) + GDP analog<br />		**[[2j7k]] - TtEF (mutant) + GDP analog<br />
Line 114:		Line 112:
	**[[6bk7]] – EF N terminal – ''Enterococcus faecalis''<br />		**[[6bk7]] – EF N terminal – ''Enterococcus faecalis''<br />
	**[[6n0i]] – PpEF 2<br />		**[[6n0i]] – PpEF 2<br />
		+	**[[2xex]] – SaEF<BR />
		+	**[[3zz0]], [[3zzt]], [[3zzu]] – SaEF (mutant) <BR />

	*''EF-G in the ribosome''		*''EF-G in the ribosome''

	**[[4v8u]], [[4v5m]], [[4v5n]] – TtEF in 70S ribosome <BR />		**[[4v8u]], [[4v5m]], [[4v5n]] – TtEF in 70S ribosome <BR />
		+	**[[2om7]], [[4v5f]] – TtEF in 70S ribosome – Cryo EM<BR />
	**[[4v9h]], [[4v9j]], [[4v9k]], [[4v9l]], [[4v9m]], [[4v90]] – TtEF in 30S ribosome <BR />		**[[4v9h]], [[4v9j]], [[4v9k]], [[4v9l]], [[4v9m]], [[4v90]] – TtEF in 30S ribosome <BR />
	**[[4v9o]], [[4v9p]] – EcEF in 30S ribosome <BR />		**[[4v9o]], [[4v9p]] – EcEF in 30S ribosome <BR />
	**[[4v9d]] – EcEF in 30S ribosome + antibiotics – Cryo-EM<BR />		**[[4v9d]] – EcEF in 30S ribosome + antibiotics – Cryo-EM<BR />
-	**[[2om7]], [[4v5f]] – TtEF in 70S ribosome – Cryo EM<BR />
	**[[1zn0]], [[2rdo]], [[3j0e]], [[4v6t]], [[4v9b]] – EcEF in 30S ribosome – Cryo-EM<BR />		**[[1zn0]], [[2rdo]], [[3j0e]], [[4v6t]], [[4v9b]] – EcEF in 30S ribosome – Cryo-EM<BR />

Line 151:		Line 151:
	*EF-Ts		*EF-Ts

-	**[[~~1tfe~~]] – ~~TtEF~~<BR />	+	**[[2uz8]] – hEF (mutant)<br />
	**[[1b64]] – hEF guanine exchange factor domain – NMR<BR />		**[[1b64]] – hEF guanine exchange factor domain – NMR<BR />
-	**[[2cp9]] – UBA domain – NMR<BR />	+	**[[2cp9]] – hEF UBA domain – NMR<BR />
	**[[1gh8]] – EF – ''Methanobacterium thermoautotrophicum'' – NMR<BR />		**[[1gh8]] – EF – ''Methanobacterium thermoautotrophicum'' – NMR<BR />
	**[[2yy3]] – PhEF <BR />		**[[2yy3]] – PhEF <BR />
-	**[[~~2uz8~~]] – ~~hEF (mutant)~~	+	**[[1tfe]] – TtEF<BR />

	*EF-1		*EF-1
Line 172:		Line 172:
	*EF-2		*EF-2

		+	**[[4v4b]] - hEF in 40S ribosome – Cryo EM<BR />
		+	**[[4cxg]], [[4cxh]] - rEF in 40S ribosome – Cryo EM<BR />
	**[[1n0v]] – yEF<BR />		**[[1n0v]] – yEF<BR />
	**[[1u2r]] – yEF + GDP<BR />		**[[1u2r]] – yEF + GDP<BR />
	**[[1n0u]], [[2e1r]], [[2npf]] – yEF + antifungal drug<BR />		**[[1n0u]], [[2e1r]], [[2npf]] – yEF + antifungal drug<BR />
	**[[1zm2]], [[1zm3]], [[1zm4]], [[1zm9]], [[3b78]], [[3b82]], [[3b8h]], [[2zit]] – yEF + exotoxin<BR />		**[[1zm2]], [[1zm3]], [[1zm4]], [[1zm9]], [[3b78]], [[3b82]], [[3b8h]], [[2zit]] – yEF + exotoxin<BR />
-	**[[4v4b]] - hEF in 40S ribosome – Cryo EM<BR />
-	**[[4cxg]], [[4cxh]] - rEF in 40S ribosome – Cryo EM<BR />
	**[[2p8w]], [[2p8x]], [[3dny]] - yEF in 80S ribosome – Cryo EM<BR />		**[[2p8w]], [[2p8x]], [[3dny]] - yEF in 80S ribosome – Cryo EM<BR />
	**[[2p8y]], [[2p8z]] - yEF+ antifungal drug in 80S ribosome – Cryo EM<BR />		**[[2p8y]], [[2p8z]] - yEF+ antifungal drug in 80S ribosome – Cryo EM<BR />
Line 199:		Line 199:
	*EF-SelB		*EF-SelB

		+	**[[5izk]], [[5izl]], [[5izm]] – hEF + GDP derivative<BR />
	**[[1lva]] – MtEF C terminal – ''Moorella thermoacetica''<BR />		**[[1lva]] – MtEF C terminal – ''Moorella thermoacetica''<BR />
	**[[2v9v]] – MtEF winged helix domain<BR />		**[[2v9v]] – MtEF winged helix domain<BR />
Line 208:		Line 209:
	**[[4ac9]] – MmEF + GDP<BR />		**[[4ac9]] – MmEF + GDP<BR />
	**[[2pjp]] – EcEF + RNA<br />		**[[2pjp]] – EcEF + RNA<br />
-	**[[5izk]], [[5izl]], [[5izm]] – hEF + GDP derivative<BR />

	*EF-Spt4 + EF-Spt5		*EF-Spt4 + EF-Spt5

-	**[[~~5xon]], [[5xog~~]] – EF-Spt4 + EF-Spt5 ~~+ EF-Tfiis + RNA polymerase II - ''Komagataella phaffii''~~ - ~~Cryo EM~~<br />	+	**[[3h7h]] – hEF-Spt4 residues 2-117 + hEF-Spt5 residues 176-273<br />
	**[[5oik]] – bEF-Spt4 + EF-Spt5 + RNA polymerase II <br />		**[[5oik]] – bEF-Spt4 + EF-Spt5 + RNA polymerase II <br />
	**[[2exu]] – yEF-Spt4 residues 1-99 + EF-Spt5 residues 285-375<br />		**[[2exu]] – yEF-Spt4 residues 1-99 + EF-Spt5 residues 285-375<br />
-	**[[3h7h]] – hEF-Spt4 residues 2-117 + hEF-Spt5 residues 176-273<br />
	**[[4zn3]], [[4zn1]] – EF-Spt4 + EF-Spt5 – ''Methanocaldococcus jannaschii'' <br />		**[[4zn3]], [[4zn1]] – EF-Spt4 + EF-Spt5 – ''Methanocaldococcus jannaschii'' <br />
		+	**[[5xon]], [[5xog]] – EF-Spt4 + EF-Spt5 + EF-Tfiis + RNA polymerase II - ''Komagataella phaffii'' - Cryo EM<br />

	*EF-Spt5		*EF-Spt5
Line 234:		Line 234:
	*EF-Spt6		*EF-Spt6

-	**[[~~3gxw~~]], [[~~3gxx]], [[3pjp~~]] – ~~EF SH2~~ domain ~~– ''Candida glabrata''~~<BR />	+	**[[4z2n]] – hEF middle domain residues 644-930<br />
		+	**[[4z2m]] – hEF middle domain + histone H3.1 + histone H4<br />
	**[[3psf]], [[3psi]] – yEF core domain residues 235-1259<BR />		**[[3psf]], [[3psi]] – yEF core domain residues 235-1259<BR />
	**[[3psj]], [[3psk]] – yEF SH2 domain residues 1247-1451<BR />		**[[3psj]], [[3psk]] – yEF SH2 domain residues 1247-1451<BR />
Line 240:		Line 241:
	**[[2l3t]] - yEF SH2 domain - NMR<BR />		**[[2l3t]] - yEF SH2 domain - NMR<BR />
	**[[3oak]] – yEF + transcription factor IWS1<br />		**[[3oak]] – yEF + transcription factor IWS1<br />
-	**[[~~4z2n~~]] ~~– hEF middle domain residues 644-930<br />~~	+	**[[3gxw]], [[3gxx]], [[3pjp]] – EF SH2 domain – ''Candida glabrata''<BR />
-	**[[~~4z2m~~]] – ~~hEF middle~~ domain ~~+ histone H3.1 + histone H4~~<br />	+

	*EF-Spt16		*EF-Spt16

Michal Harel: New page: ==3D structures of elongation factor== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *EF-Tu **1efm, 1efc...

2019-06-19T08:28:30Z

New page: ==3D structures of elongation factor== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *EF-Tu **1efm, 1efc...

New page

==3D structures of elongation factor==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

*EF-Tu

**[[1efm]], [[1efc]], [[1dg1]], [[2fx3]], [[1etu]], [[5mi3]] – EcEF – ''Escherichia coli'' 
**[[5mi8]], [[5mi9]] – EcEF (mutant) 
**[[1qzd]] – EcEF – Cryo EM 
**[[3u2q]] – EcEF + drug 
**[[1mj1]] – EcEF + Phe-tRNA + S12 + S13 + L11 – Cryo EM 
**[[3ep2]] - EcEF + tRNA + S12 + L11 + 16SRRNA + 23SRRNA – Cryo EM 
**[[1ttt]], [[1ob5]] – TaEF + Phe-tRNA + GDPNP - ''Thermus aquaticus'' 
**[[1b23]] - TaEF + Cys-tRNA 
**[[1ls2]] – yEF + Phe-tRNA – yeast – Cryo EM 
**[[3wxm]] – ApEF + plethora protein – ''Aeropyrum pernix'' 
**[[4h9g]], [[4lbv]], [[4lbw]], [[4lby]], [[4lbz]], [[4lc0]] – TtEF – ''Thermus thermophilus'' 
**[[4j0q]] – PpEF – ''Pseudomonas putida'' 
**[[5w75]] – EF – ''Thermotoga neapolitana'' 
**[[5tbf]] – EF domain 2-3– ''Vibrio cholerae'' 

*''EF-Tu complex with antibiotics''

**[[1ob2]] - yEF + Phe-tRNA + antibiotic 
**[[4v8q]] - TtEF + antibiotic in 30S ribosome 
**[[1ha3]] - TtEF + antibiotic + GDP 
**[[2c77]], [[2c78]] - TtEF + antibiotic + GTP analog 
**[[4v68]] – TtEF + antibiotic in 70S ribosome – Cryo EM 
**[[2bvn]] - EcEF + GDP NP + antibiotic 
**[[1d8t]], [[2hcj]], [[2hdn]], [[3u6b]], [[3u6k]], [[4g5g]], [[5jbq]] – EcEF + antibiotic

*''EF-Tu complex with nucleotide''

**[[6eze]] – EcEF + GDP derivative 
**[[5opd]] – EcEF + GTP 
**[[1exm]] – TtEF + GTP analog 
**[[1eft]] – TaEF + GNP – ''Thermus aquaticus'' 
**[[1tui]] – TaEF + GDP 
**[[1d2e]] – bEF + GDP – bovine 
**[[1jny]], [[1skq]] – SsEF + GDP – ''Sulfolobus solfataricus'' 
**[[3wya]] – PhEF + GDP - ''Pyrococcus horikoshii'' 
**[[6mij]] – AbEF + GDP – ''Acinetobacter baumannii'' 
**[[6gfu]] – EF + GDP – synthetic 

*''EF-Tu complex with protein''

**[[3vmf]] – ApEF + translation termination factor 
**[[3wy9]] – PhEF + L12 
**[[4p3y]] – EcEF + thiol:disulfide interchange protein 
**[[5i4r]], [[5i4q]] – EcEF + CDIA + CDII 
**[[4zv4]] – PaEF + TSE6 - ''Pseudomonas aeruginosa'' 

*''EF-Tu with EF-Ts''

**[[1efu]], [[3agp]], [[3agq]], [[4pc1]] – EcEF + EcEF-Ts 
**[[3avt]], [[3avu]] , [[3avv]], [[3avw]], [[3avx]], [[3avy]], [[3vnu]] , [[3vnv]], [[4fwt]] – EcEF + EcEF-Ts + RNA 
**[[3mmp]] – EcEF + EcEF-Ts + RNA replicase beta chain 
**[[4q7j]] – EcEF + EcEF-Ts + Q beta replicase + S1 
**[[4r71]] – EcEF + EcEF-Ts + RNA polymerase β chain + S1 
**[[4pc7]] – EcEF + EcEF-Ts + antibiotic + GNP 
**[[4pc2]], [[4pc3]], [[4pc6]] – EcEF + EcEF-Ts + GDP derivative 
**[[1aip]] - TtEF + TtEF-Ts - ''Thermus thermophilus'' 
**[[1xb2]] – bEF + EF-Ts - bovine 
**[[1f60]] – yEF + EF-Ts C terminal 
**[[1g7c]] - yEF + EF-Ts C terminal + GDPNP 
**[[1ije]], [[1ijf]] - yEF + EF-Ts C terminal + GDP 
**[[2b7b]] - yEF + EF-Ts C terminal (mutant) + GDP 
**[[2b7c]] - yEF + EF-Ts C terminal (mutant)

*''EF-Tu in the ribosome''

**[[3eq3]], [[3eq4]] – EcEF in 80S ribosome – Cryo EM 
**[[4v6l]], [[4v6k]], [[4v69]] - EcEF in 30S ribosome – Cryo EM 
**[[1zc8]], [[3dwu]] – TtEF in 70S ribosome – Cryo EM 
**[[4v5g]], [[4v5l]], [[4v5p]], [[4v5q]], [[4v5r]], [[4v5s]] - TtEF in 70S ribosome

*EF-SII

**[[1tfi]] – hEF – human – NMR 
**[[3ndq]] - hEF domain II 
**[[1enw]] – yEF domain II – NMR 
**[[1eo0]] - yEF domain I – NMR 
**[[2xex]] – SaEF – ''Staphylococcus aureus'' 
**[[1pqv]], [[1y1v]] – yEF + RNA polymerase II 
**[[1y1y]], [[3gtm]] – yEF + RNA polymerase II + RNA 
**[[1wjt]] – mEF N terminal – mouse – NMR 
**[[2m1h]] – EF PWWP domain – ''Trypanosoma brucei'' – NMR 

*EF-ELL2

**[[2e5n]] – hEF N2 domain - NMR 
**[[5jw9]] – hEF + AFF4 peptide 

*EF-G

**[[1efg]], [[1elo]], [[1ktv]], [[1wdt]], [[2dy1]] – TtEF 
**[[4m1k]], [[4myt]], [[4myu]] – TtEF (mutant) 
**[[1pn6]], [[3izp]] – TtEF – Cryo EM 
**[[1fnm]], [[2bm0]], [[2bm1]] – TtEF (mutant) 
**[[2bcw]] – TtEF + L11 + L7/L12 
**[[2xex]] – SaEF 
**[[3zz0]], [[3zzt]], [[3zzu]] – SaEF (mutant) 
**[[2bv3]] - TtEF (mutant) + GTP analog 
**[[2j7k]] - TtEF (mutant) + GDP analog 
**[[1dar]], [[2efg]] – TtEF + GDP 
**[[1jqm]], [[1jqs]] – EcEF + L11 – Cryo EM 
**[[4fn5]] – PaEF 
**[[5tv2]] – EF – ''Vibrio vulnificus'' 
**[[5ty0]] – EF N terminal – ''Legionella pneumophila'' 
**[[5vh6]] – EF N terminal – ''Bacillus subtilis'' 
**[[6b8d]] – EF N terminal – ''Haemophilus influenzae'' 
**[[6not]] – EF – ''Rickettsia prowazekii'' 
**[[6bk7]] – EF N terminal – ''Enterococcus faecalis'' 
**[[6n0i]] – PpEF 2 

*''EF-G in the ribosome''

**[[4v8u]], [[4v5m]], [[4v5n]] – TtEF in 70S ribosome 
**[[4v9h]], [[4v9j]], [[4v9k]], [[4v9l]], [[4v9m]], [[4v90]] – TtEF in 30S ribosome 
**[[4v9o]], [[4v9p]] – EcEF in 30S ribosome 
**[[4v9d]] – EcEF in 30S ribosome + antibiotics – Cryo-EM 
**[[2om7]], [[4v5f]] – TtEF in 70S ribosome – Cryo EM 
**[[1zn0]], [[2rdo]], [[3j0e]], [[4v6t]], [[4v9b]] – EcEF in 30S ribosome – Cryo-EM 

*EF-GreA/GreB

**[[2pn0]] – EF – ''Nitrosomonas europaea'' 
**[[2p4v]] – EcEF-GreB 
**[[1grj]] – EcEF-GreA 

*EF-NusA

**[[1wcl]], [[1wcn]] – EcEF C terminal – NMR 
**[[2kwp]] - EcEF N terminal – NMR 
**[[2jzb]] – EcEF + RNA polymerase subunit α - NMR 

*EF-P

**[[1ueb]] – TtEF 
**[[4v6a]] – TtEF in 70S ribosome 
**[[3oyy]] – PaEF 
**[[6j7m]] – PaEF + EARP 
**[[3tre]] – EF – ''Coxiella burnetii'' 
**[[3a5z]] – EcEF + lysyl-tRNA synthetase 
**[[1yby]] – EF – ''Clostridium thermocellum'' 
**[[5j3b]] – AbEF 
**[[5wxk]] – EF + EARP – ''Neisseria meningitidis'' 

*EF-Ts

**[[1tfe]] – TtEF 
**[[1b64]] – hEF guanine exchange factor domain – NMR 
**[[2cp9]] – UBA domain – NMR 
**[[1gh8]] – EF – ''Methanobacterium thermoautotrophicum'' – NMR 
**[[2yy3]] – PhEF 
**[[2uz8]] – hEF (mutant)

*EF-1

**[[5dqs]] – hEF β+γ 
**[[5jpo]] – hEF γ+δ 
**[[1pbu]] – hEF γ C terminal (mutant) - NMR 
**[[2mvm]], [[2mvn]] – hEF δ-1 CAR domain – NMR 
**[[5bmu]] – hEF ε-1 + Glu tRNA ligase 
**[[5y6l]] – hEF ε-1 (mutant) + MetRS + AspRS + Glu/Pro tRNA ligase + P38 
**[[4c0s]] – rEF α-2 – rabbit 
**[[5o8w]] – yEF α+β 
**[[1nhy]] – yEF γ N terminal 

*EF-2

**[[1n0v]] – yEF 
**[[1u2r]] – yEF + GDP 
**[[1n0u]], [[2e1r]], [[2npf]] – yEF + antifungal drug 
**[[1zm2]], [[1zm3]], [[1zm4]], [[1zm9]], [[3b78]], [[3b82]], [[3b8h]], [[2zit]] – yEF + exotoxin 
**[[4v4b]] - hEF in 40S ribosome – Cryo EM 
**[[4cxg]], [[4cxh]] - rEF in 40S ribosome – Cryo EM 
**[[2p8w]], [[2p8x]], [[3dny]] - yEF in 80S ribosome – Cryo EM 
**[[2p8y]], [[2p8z]] - yEF+ antifungal drug in 80S ribosome – Cryo EM 
**[[5h7j]] - PhEF 
**[[5h7l]] - PhEF + L12 
**[[5h7k]] - PhEF + GDP 

*EF-3

**[[2ix3]] – yEF 
**[[2iwh]] – yEF + ADPNP 
**[[2iw3]] – yEF + ADP 
**[[2ix8]] – yEF in 80S ribosome – Cryo EM 

*EF-4 (lepA)

**[[2ywh]], [[2ywe]], [[2ywf]], [[2ywg]] - AalepA + nucleotide - ''Aquifex aeolicus'' 
**[[3cb4]] - EclepA 
**[[3deg]] - EclepA in 70S ribosome + GMPPNP – Cryo EM 

*EF-SelB

**[[1lva]] – MtEF C terminal – ''Moorella thermoacetica'' 
**[[2v9v]] – MtEF winged helix domain 
**[[1wsu]], [[2uwm]] – MtEF + RNA 
**[[2ply]] – MtEF (mutant) + RNA 
**[[4zu9]] - AaEF 
**[[4aca]] – MmEF – ''Methanococcus maripaludis'' 
**[[4acb]] – MmEF + GTP analog 
**[[4ac9]] – MmEF + GDP 
**[[2pjp]] – EcEF + RNA 
**[[5izk]], [[5izl]], [[5izm]] – hEF + GDP derivative 

*EF-Spt4 + EF-Spt5

**[[5xon]], [[5xog]] – EF-Spt4 + EF-Spt5 + EF-Tfiis + RNA polymerase II - ''Komagataella phaffii'' - Cryo EM 
**[[5oik]] – bEF-Spt4 + EF-Spt5 + RNA polymerase II 
**[[2exu]] – yEF-Spt4 residues 1-99 + EF-Spt5 residues 285-375 
**[[3h7h]] – hEF-Spt4 residues 2-117 + hEF-Spt5 residues 176-273 
**[[4zn3]], [[4zn1]] – EF-Spt4 + EF-Spt5 – ''Methanocaldococcus jannaschii'' 

*EF-Spt5

**[[2e6z]] – hEF KOW2 motif residues 420-471 – NMR 
**[[2do3]] – hEF KOW3 motif residues 462-523 – NMR 
**[[6eqy]] – hEF KOW4 motif residues 522-647 – NMR 
**[[2e70]] – hEF KOW5 motif residues 694-757 – NMR 
**[[6er0]] – hEF KOW6 motif residues 961-1087 – NMR 
**[[2do3]], [[2e6z]], [[2e70]] – hEF KOW motif residues 694-757 – NMR 
**[[5ohq]] – hEF KOW6-KOW7 domain residues 939-1087 
**[[5oho]] – hEF KOWX-KOW4 domain residues 536-646 
**[[4ytl]] – yEF KOW2-KOW3 domain residues 534-632 
**[[4ytk]] – yEF KOW1-linker domain residues 382-511 
**[[2exu]] – yEF 

*EF-Spt6

**[[3gxw]], [[3gxx]], [[3pjp]] – EF SH2 domain – ''Candida glabrata'' 
**[[3psf]], [[3psi]] – yEF core domain residues 235-1259 
**[[3psj]], [[3psk]] – yEF SH2 domain residues 1247-1451 
**[[5vkl]], [[5vko]] – yEF SH2 domain + RPB1 peptide 
**[[2l3t]] - yEF SH2 domain - NMR 
**[[3oak]] – yEF + transcription factor IWS1 
**[[4z2n]] – hEF middle domain residues 644-930 
**[[4z2m]] – hEF middle domain + histone H3.1 + histone H4 

*EF-Spt16

**[[5umu]], [[5umt]], [[5xm2]] – hEF 
**[[5e5b]] - hEF N-terminal 

*EF-M2-1

**[[5nkx]], [[5noh]] – EF core domain – human respiratory cyncytial virus 

*EF-TEFM mitochondrial

**[[5ol9]] - hEF N-terminal 
**[[5ol8]] - hEF C-terminal 
**[[5ola]] - hEF + RNA polymerase + RNA + DNA 

*EF-CA150

**[[2dod]], [[2doe]], [[2dof]], [[2e71]], [[2kiq]], [[2kis]] – hEF FF domain – NMR 
**[[3hfh]] – hEF FF domain 
**[[2ysi]]– mEF WW domain - NMR 

*Elongin A

**[[4hfx]] – hEloA F-box domain 

*Elongin C

**[[5zb2]] – yEloC + Rad7 
**[[1hv2]] - yEloC + von-Hippel Lindau disease tumor suppressor - NMR 

*Elongin BC complex

**[[1lqb]], [[1lm8]] – hEloBC + von-Hippel Lindau disease tumor suppressor + hypoxia inducible factor 1 α 
**[[3zrc]], [[3ztc]], [[3ztd]], [[3zun]], [[6fmi]], [[6fmj]], [[6fmk]], [[5nw2]], [[5nw1]], [[5nw0]], [[5nvz]], [[5nvy]], [[5nvx]], [[5nvw]], [[5nvv]], [[4w9l]], [[4w9k]], [[4w9j]], [[4w9i]], [[4w9h]], [[4w9g]], [[4w9f]], [[4w9e]], [[4w9d]], [[4w9c]], [[6gfy]] - hEloBC + von-Hippel Lindau disease tumor suppressor + inhibitor 
**[[5t35]] - hEloBC + von-Hippel Lindau disease tumor suppressor + BRD4 
**[[4wqo]] - hEloBC + von-Hippel Lindau disease tumor suppressor + cullin-2 
**[[6hr2]], [[6hay]], [[6hax]] - hEloBC + von-Hippel Lindau disease tumor suppressor + transcription activator 
**[[6gmr]], [[6gfx]], [[6bvb]] - hEloBC + von-Hippel Lindau disease tumor suppressor + hypoxia inducible factor peptide 
**[[5n4w]] - hEloBC + von-Hippel Lindau disease tumor suppressor + cullin-2 + RBX1 
**[[3zrf]], [[5lli]], [[6gmx]], [[6gmq]], [[6gmn]], [[6gfz]] - hEloBC + von-Hippel Lindau disease tumor suppressor 
**[[2c9w]], [[2izv]], [[2jz3]], [[5bo4]] – hEloBC + suppressor of cytokine signaling 
**[[6c5x]] – hEloBC + suppressor of cytokine signaling + Gp130 peptide 
**[[6i5n]], [[6i5j]] – hEloBC + suppressor of cytokine signaling + growth hormone receptor peptide 
**[[6i4x]] – hEloBC + suppressor of cytokine signaling + erythropoietin peptide 
**[[3dcg]] – hEloBC + virion infectivity factor 
**[[3zkj]] - hEloBC + ankyrin rep 
**[[1vcb]] – hEloBC + VHL 
**[[2fnj]] - mEloBC + GUSTAVUS
}}

[[Category:Topic Page]]