Ferredoxin NADP+ Reductase - Revision history

Alexander Berchansky at 10:58, 2 January 2023

2023-01-02T10:58:33Z

←Older revision		Revision as of 10:58, 2 January 2023
Line 18:		Line 18:
	==Other Functions==		==Other Functions==

-	FNR is also an active protein in plants, and is found in the chloroplast and thylakoid membrane of the cell. The FNR reductive mechanism is responsible for the transfer of the final electrons during photosynthesis from photosystem I to NADPH, which then goes on to participate the Calvin cycle as a reducing cofactor.	+	FNR is also an active protein in plants, and is found in the chloroplast and thylakoid membrane of the cell. The FNR reductive mechanism is responsible for the transfer of the final electrons during photosynthesis from photosystem I to NADPH, which then goes on to participate the [[Calvin cycle]] as a reducing cofactor.
	In other organisms, FNR plays a role in metabolism such as oxidative stress response and steroid metabolism.[http://en.wikipedia.org/wiki/Ferredoxin—NADP(%2B)_reductase]		In other organisms, FNR plays a role in metabolism such as oxidative stress response and steroid metabolism.[http://en.wikipedia.org/wiki/Ferredoxin—NADP(%2B)_reductase]

Jaime Prilusky at 04:05, 25 October 2020

2020-10-25T04:05:04Z

←Older revision		Revision as of 04:05, 25 October 2020
Line 30:		Line 30:

	== 3D Structures of Ferredoxin NADP+ reductase ==		== 3D Structures of Ferredoxin NADP+ reductase ==
-	[[Ferredoxin NADP+ ~~reductase~~ 3D ~~structure~~]]	+	[[Ferredoxin NADP+ Reductase 3D structures]]

	</StructureSection>		</StructureSection>

Michal Harel at 08:53, 27 June 2019

2019-06-27T08:53:24Z

←Older revision		Revision as of 08:53, 27 June 2019
Line 33:		Line 33:

	</StructureSection>		</StructureSection>
-
-	== 3D Structures of Ferredoxin NADP+ reductase ==
-
-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	*FNR
-
-	**[[3lxd]] – FNR ARR – ''Novosphingobium aromaticivorans''<br />
-	**[[2x3u]], [[2bmw]], [[1w34]], [[1w35]], [[1h42]], [[1gr1]], [[1h85]], [[4bpr]], [[4c43]] – AnFNR (mutant) – Anabena<br />
-	**[[1ogi]], [[1ogj]] - AnFNR fragment (mutant)<br />
-	**[[2vyq]], [[1go2]], [[3zbt]], [[3zbu]] - NoFNR fragment (mutant) – Nostoc<br />
-	**[[1qgy]], [[1bqe]], [[1qgz]], [[1qh0]], [[1e62]], [[1e63]], [[1e64]], [[1b2r]], [[1bjk]] - NoFNR (mutant)<br />
-	**[[1que]] - NoFNR<br />
-	**[[3fpk]] - FNR – ''Salmonela typhimurium''<br />
-	**[[2bgj]] - RcFNR (mutant)<br />
-	**[[2qdx]] - PaFNR – ''Pseudomonas aeruginosa''<br />
-	**[[2gqw]], [[2gr0]], [[2gr1]], [[1d7y]] – PsFNR - ''Pseudomonas sp.''<br />
-	**[[2gr3]] – PsFNR (mutant)<br />
-	**[[2rc5]] - LiFNR – ''Leptospira interrogans''<br />
-	**[[2b5o]] - FNR – ''Synechococcus sp.''<br />
-	**[[1sm4]] - FNR – paprika<br />
-	**[[1a8p]] - FNR – ''Azotobacter vinelandii''<br />
-	**[[1fdr]] - EcFNR (mutant) – ''Escherichia coli''<br />
-	**[[1frn]], [[1fnb]] - spFNR – spinach<br />
-	**[[1bx0]], [[1bx1]], [[1frq]] – spFNR (mutant)<br />
-	**[[2xnc]], [[1qg0]] – pFNR - pea<br />
-	**[[4af6]], [[4af7]] – pFNR (mutant) <br />
-	**[[3ab1]] – FNR – ''Chlorobaculum tepidum''<br />
-	**[[4f7d]] – BtFNR no FAD – ''Burkholderia thailandensis''<br />
-	**[[4fk8]] - BtFNR <br />
-	**[[3jqr]] - PfFNR (mutant) – ''Plasmodium falciparum''<br />
-	**[[4b4d]] – FNR – ''Xanthomonas axonopodis''<br />
-
-	*FNR+NADP
-
-	**[[1gjr]], [[1w87]] - AnFNR fragment+NADP<br />
-	**[[2bsa]] - AnFNR (mutant)+NADP<br />
-	**[[2vzl]], [[1quf]], [[3zc3]] - NoFNR fragment (mutant)+NAD<br />
-	**[[2vnh]] - RcFNR+NADP – ''Rhodobacter capsulatus''<br />
-	**[[3crz]] - PaFNR + NADP<br />
-	**[[2rc6]] - LiFNR+NADP<br />
-	**[[1qfy]], [[1qfz]], [[1qga]] - pFNR (mutant)+NADP <br />
-	**[[2vnj]], [[2vnk]] - RcFNR+NADP<br />
-	**[[2xnj]] - EcFNR+NADP<br />
-	**[[1lqu]] - MtFNR+NADP - ''Mycobacterium tuberculosis''<br />
-	**[[1f3p]] – PsFNR + NADP<br />
-	**[[3lzw]], [[3lzx]] – FNR 2 + NADP – ''Bacillus subtilis''<br />
-	**[[5thx]] - NgFNR + NADP + FAD – ''Neisseria gonorrhoeae''<br />
-	**[[5vw2]], [[5vw3]], [[5vw6]], [[5vw7]], [[5vw8]], [[5vwb]] - mFNR (mutant) + NADP + FAD derivative - maize<br />
-
-	*FNR+Fd
-
-	**[[1gaq]] - mFNR+ FAD + Fd-1 - maize<br />
-	**[[5h5j]] - mFNR + FAD + Fd-3<br />
-	**[[1ewy]] - NoFNR fragment + Fd<br />
-	**[[3jqp]], [[3jqr]] - FNR (mutant)+2P-AMP – ''Plasmodium falciparum''<br />
-
-	*FNR other complexes
-
-	**[[2vni]] - RcFNR+A2P<br />
-	**[[2bgi]] - RcFNR (mutant)+detergent<br />
-	**[[2yvj]], [[2yvf]], [[2yvg]] - pFNR+ NAD + biphenyl dioxygenase Fd subunit<br />
-	**[[3jqq]] – PfFNR + A2P<br />
-	**[[3mhp]] – pFNR + peptide<br />
-	**[[3jqp]] - FNR (mutant)+A2P<br />
-	**[[2gr0]], [[2gr2]] – SpFNR + ADP derivative<br />
-	**[[2c7g]] - MtFNR (mutant) + ODP – ''Mycobacterium tuberculosis''<br />
-	**[[1lqt]] - MtFNR + ODP<br />
-	**[[1fnc]], [[1fnd]] – spFNR + A2P<br />
-	**[[5tr9]] - NgFNR + FAD <br />
-	**[[3lo8]], [[3lvb]], [[1jb9]], [[1gaw]] – mFNR + FAD <br />
-	**[[5vw4]], [[5vw5]], [[5vw9]] - mFNR (mutant) + nicotinamide + FAD <br />
-	**[[5zbv]], [[5twb]], [[5twc]], [[6a4j]] – FNR + FAD – ''Staphylococcus aureus''<br />
-	**[[5xhu]] – BsFNR + FAD <br />
-	**[[6gar]], [[6gas]] – FNR + FAD – ''Bacillus cereus''<br />
-	**[[5ygq]] – FNR + FAD – ''Rhodopseudomonas palustris''<br />
-	**[[5h59]] - mFNR + FAD <br />
-	**[[5vwa]] - mFNR (mutant) + FAD <br />
-	**[[4k1x]] - RcFNR (mutant) + FAD <br />
-	**[[5vj7]] – FNR + oxidoreductase + FAD + Fe2S2 – ''Pyrococcus furiosus''<br />
-	}}
-

	== References ==		== References ==

Michal Harel at 08:52, 27 June 2019

2019-06-27T08:52:15Z

←Older revision		Revision as of 08:52, 27 June 2019
Line 119:		Line 119:
	== References ==		== References ==
	<references/>		<references/>
		+
		+	[[Category:Topic Page]]

Michal Harel at 08:50, 27 June 2019

2019-06-27T08:50:21Z

←Older revision		Revision as of 08:50, 27 June 2019
Line 5:		Line 5:
	<StructureSection load='4FK8' size='340' frame='true' side='right' caption='FNR protein containg FAD (PDB code [[4fk8]])' scene=''>		<StructureSection load='4FK8' size='340' frame='true' side='right' caption='FNR protein containg FAD (PDB code [[4fk8]])' scene=''>

		+	==Function==

	'''Ferredoxin NADP<sup>+</sup> reductase''' [http://en.wikipedia.org/wiki/Ferredoxin—NADP(%2B)_reductase] is an enzyme that catalyzes the reduction of NADP<sup>+</sup> to NADPH. This enzyme belongs to a family of enzymes called oxidoreductases[http://en.wikipedia.org/wiki/Oxidoreductase] that contain iron-sulfur proteins as electron donors and NAD<sup>+</sup> or NADP<sup>+</sup> as electron acceptors. FAD, [flavin adenine dinucleotide][http://en.wikipedia.org/wiki/Flavin_adenine_dinucleotide], is also a cofactor of FNR. The ferredoxin NADP<sup>+</sup> reductase participates in a general reaction that proceeds as follows:		'''Ferredoxin NADP<sup>+</sup> reductase''' [http://en.wikipedia.org/wiki/Ferredoxin—NADP(%2B)_reductase] is an enzyme that catalyzes the reduction of NADP<sup>+</sup> to NADPH. This enzyme belongs to a family of enzymes called oxidoreductases[http://en.wikipedia.org/wiki/Oxidoreductase] that contain iron-sulfur proteins as electron donors and NAD<sup>+</sup> or NADP<sup>+</sup> as electron acceptors. FAD, [flavin adenine dinucleotide][http://en.wikipedia.org/wiki/Flavin_adenine_dinucleotide], is also a cofactor of FNR. The ferredoxin NADP<sup>+</sup> reductase participates in a general reaction that proceeds as follows:
Line 27:		Line 28:

	In its active form, the protein is a <scene name='69/699901/Dimeric_fnr/1'>dimer</scene> and contains a [4Fe-4S]<sup>+2</sup> cluster. When inactive, the protein is monomeric and containts a [3Fe-4S]<sup>+2</sup> cluster. FNR in its <scene name='69/699901/Monomeric_fnr/1'>monomer</scene> form can be seen here, with bound NADP and FAD.<ref> PMID: 21166900 </ref>		In its active form, the protein is a <scene name='69/699901/Dimeric_fnr/1'>dimer</scene> and contains a [4Fe-4S]<sup>+2</sup> cluster. When inactive, the protein is monomeric and containts a [3Fe-4S]<sup>+2</sup> cluster. FNR in its <scene name='69/699901/Monomeric_fnr/1'>monomer</scene> form can be seen here, with bound NADP and FAD.<ref> PMID: 21166900 </ref>
		+
		+	== 3D Structures of Ferredoxin NADP+ reductase ==
		+	[[Ferredoxin NADP+ reductase 3D structure]]

	</StructureSection>		</StructureSection>
Line 102:		Line 106:
	**[[3lo8]], [[3lvb]], [[1jb9]], [[1gaw]] – mFNR + FAD <br />		**[[3lo8]], [[3lvb]], [[1jb9]], [[1gaw]] – mFNR + FAD <br />
	**[[5vw4]], [[5vw5]], [[5vw9]] - mFNR (mutant) + nicotinamide + FAD <br />		**[[5vw4]], [[5vw5]], [[5vw9]] - mFNR (mutant) + nicotinamide + FAD <br />
-	**[[5zbv]], [[5twb]], [[5twc]] – FNR + FAD – ''Staphylococcus aureus''<br />	+	**[[5zbv]], [[5twb]], [[5twc]], [[6a4j]] – FNR + FAD – ''Staphylococcus aureus''<br />
	**[[5xhu]] – BsFNR + FAD <br />		**[[5xhu]] – BsFNR + FAD <br />
		+	**[[6gar]], [[6gas]] – FNR + FAD – ''Bacillus cereus''<br />
		+	**[[5ygq]] – FNR + FAD – ''Rhodopseudomonas palustris''<br />
	**[[5h59]] - mFNR + FAD <br />		**[[5h59]] - mFNR + FAD <br />
	**[[5vwa]] - mFNR (mutant) + FAD <br />		**[[5vwa]] - mFNR (mutant) + FAD <br />

Michal Harel at 10:54, 13 January 2019

2019-01-13T10:54:24Z

←Older revision		Revision as of 10:54, 13 January 2019
Line 27:		Line 27:

	In its active form, the protein is a <scene name='69/699901/Dimeric_fnr/1'>dimer</scene> and contains a [4Fe-4S]<sup>+2</sup> cluster. When inactive, the protein is monomeric and containts a [3Fe-4S]<sup>+2</sup> cluster. FNR in its <scene name='69/699901/Monomeric_fnr/1'>monomer</scene> form can be seen here, with bound NADP and FAD.<ref> PMID: 21166900 </ref>		In its active form, the protein is a <scene name='69/699901/Dimeric_fnr/1'>dimer</scene> and contains a [4Fe-4S]<sup>+2</sup> cluster. When inactive, the protein is monomeric and containts a [3Fe-4S]<sup>+2</sup> cluster. FNR in its <scene name='69/699901/Monomeric_fnr/1'>monomer</scene> form can be seen here, with bound NADP and FAD.<ref> PMID: 21166900 </ref>
		+
		+	</StructureSection>

	== 3D Structures of Ferredoxin NADP+ reductase ==		== 3D Structures of Ferredoxin NADP+ reductase ==

Michal Harel at 10:53, 13 January 2019

2019-01-13T10:53:15Z

←Older revision		Revision as of 10:53, 13 January 2019
Line 27:		Line 27:

	In its active form, the protein is a <scene name='69/699901/Dimeric_fnr/1'>dimer</scene> and contains a [4Fe-4S]<sup>+2</sup> cluster. When inactive, the protein is monomeric and containts a [3Fe-4S]<sup>+2</sup> cluster. FNR in its <scene name='69/699901/Monomeric_fnr/1'>monomer</scene> form can be seen here, with bound NADP and FAD.<ref> PMID: 21166900 </ref>		In its active form, the protein is a <scene name='69/699901/Dimeric_fnr/1'>dimer</scene> and contains a [4Fe-4S]<sup>+2</sup> cluster. When inactive, the protein is monomeric and containts a [3Fe-4S]<sup>+2</sup> cluster. FNR in its <scene name='69/699901/Monomeric_fnr/1'>monomer</scene> form can be seen here, with bound NADP and FAD.<ref> PMID: 21166900 </ref>
		+
		+	== 3D Structures of Ferredoxin NADP+ reductase ==
		+
		+	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
		+	{{#tree:id=OrganizedByTopic\|openlevels=0\|
		+
		+	*FNR
		+
		+	**[[3lxd]] – FNR ARR – ''Novosphingobium aromaticivorans''<br />
		+	**[[2x3u]], [[2bmw]], [[1w34]], [[1w35]], [[1h42]], [[1gr1]], [[1h85]], [[4bpr]], [[4c43]] – AnFNR (mutant) – Anabena<br />
		+	**[[1ogi]], [[1ogj]] - AnFNR fragment (mutant)<br />
		+	**[[2vyq]], [[1go2]], [[3zbt]], [[3zbu]] - NoFNR fragment (mutant) – Nostoc<br />
		+	**[[1qgy]], [[1bqe]], [[1qgz]], [[1qh0]], [[1e62]], [[1e63]], [[1e64]], [[1b2r]], [[1bjk]] - NoFNR (mutant)<br />
		+	**[[1que]] - NoFNR<br />
		+	**[[3fpk]] - FNR – ''Salmonela typhimurium''<br />
		+	**[[2bgj]] - RcFNR (mutant)<br />
		+	**[[2qdx]] - PaFNR – ''Pseudomonas aeruginosa''<br />
		+	**[[2gqw]], [[2gr0]], [[2gr1]], [[1d7y]] – PsFNR - ''Pseudomonas sp.''<br />
		+	**[[2gr3]] – PsFNR (mutant)<br />
		+	**[[2rc5]] - LiFNR – ''Leptospira interrogans''<br />
		+	**[[2b5o]] - FNR – ''Synechococcus sp.''<br />
		+	**[[1sm4]] - FNR – paprika<br />
		+	**[[1a8p]] - FNR – ''Azotobacter vinelandii''<br />
		+	**[[1fdr]] - EcFNR (mutant) – ''Escherichia coli''<br />
		+	**[[1frn]], [[1fnb]] - spFNR – spinach<br />
		+	**[[1bx0]], [[1bx1]], [[1frq]] – spFNR (mutant)<br />
		+	**[[2xnc]], [[1qg0]] – pFNR - pea<br />
		+	**[[4af6]], [[4af7]] – pFNR (mutant) <br />
		+	**[[3ab1]] – FNR – ''Chlorobaculum tepidum''<br />
		+	**[[4f7d]] – BtFNR no FAD – ''Burkholderia thailandensis''<br />
		+	**[[4fk8]] - BtFNR <br />
		+	**[[3jqr]] - PfFNR (mutant) – ''Plasmodium falciparum''<br />
		+	**[[4b4d]] – FNR – ''Xanthomonas axonopodis''<br />
		+
		+	*FNR+NADP
		+
		+	**[[1gjr]], [[1w87]] - AnFNR fragment+NADP<br />
		+	**[[2bsa]] - AnFNR (mutant)+NADP<br />
		+	**[[2vzl]], [[1quf]], [[3zc3]] - NoFNR fragment (mutant)+NAD<br />
		+	**[[2vnh]] - RcFNR+NADP – ''Rhodobacter capsulatus''<br />
		+	**[[3crz]] - PaFNR + NADP<br />
		+	**[[2rc6]] - LiFNR+NADP<br />
		+	**[[1qfy]], [[1qfz]], [[1qga]] - pFNR (mutant)+NADP <br />
		+	**[[2vnj]], [[2vnk]] - RcFNR+NADP<br />
		+	**[[2xnj]] - EcFNR+NADP<br />
		+	**[[1lqu]] - MtFNR+NADP - ''Mycobacterium tuberculosis''<br />
		+	**[[1f3p]] – PsFNR + NADP<br />
		+	**[[3lzw]], [[3lzx]] – FNR 2 + NADP – ''Bacillus subtilis''<br />
		+	**[[5thx]] - NgFNR + NADP + FAD – ''Neisseria gonorrhoeae''<br />
		+	**[[5vw2]], [[5vw3]], [[5vw6]], [[5vw7]], [[5vw8]], [[5vwb]] - mFNR (mutant) + NADP + FAD derivative - maize<br />
		+
		+	*FNR+Fd
		+
		+	**[[1gaq]] - mFNR+ FAD + Fd-1 - maize<br />
		+	**[[5h5j]] - mFNR + FAD + Fd-3<br />
		+	**[[1ewy]] - NoFNR fragment + Fd<br />
		+	**[[3jqp]], [[3jqr]] - FNR (mutant)+2P-AMP – ''Plasmodium falciparum''<br />
		+
		+	*FNR other complexes
		+
		+	**[[2vni]] - RcFNR+A2P<br />
		+	**[[2bgi]] - RcFNR (mutant)+detergent<br />
		+	**[[2yvj]], [[2yvf]], [[2yvg]] - pFNR+ NAD + biphenyl dioxygenase Fd subunit<br />
		+	**[[3jqq]] – PfFNR + A2P<br />
		+	**[[3mhp]] – pFNR + peptide<br />
		+	**[[3jqp]] - FNR (mutant)+A2P<br />
		+	**[[2gr0]], [[2gr2]] – SpFNR + ADP derivative<br />
		+	**[[2c7g]] - MtFNR (mutant) + ODP – ''Mycobacterium tuberculosis''<br />
		+	**[[1lqt]] - MtFNR + ODP<br />
		+	**[[1fnc]], [[1fnd]] – spFNR + A2P<br />
		+	**[[5tr9]] - NgFNR + FAD <br />
		+	**[[3lo8]], [[3lvb]], [[1jb9]], [[1gaw]] – mFNR + FAD <br />
		+	**[[5vw4]], [[5vw5]], [[5vw9]] - mFNR (mutant) + nicotinamide + FAD <br />
		+	**[[5zbv]], [[5twb]], [[5twc]] – FNR + FAD – ''Staphylococcus aureus''<br />
		+	**[[5xhu]] – BsFNR + FAD <br />
		+	**[[5h59]] - mFNR + FAD <br />
		+	**[[5vwa]] - mFNR (mutant) + FAD <br />
		+	**[[4k1x]] - RcFNR (mutant) + FAD <br />
		+	**[[5vj7]] – FNR + oxidoreductase + FAD + Fe2S2 – ''Pyrococcus furiosus''<br />
		+	}}
		+

	== References ==		== References ==
	<references/>		<references/>

Michal Harel at 10:50, 13 January 2019

2019-01-13T10:50:17Z

←Older revision		Revision as of 10:50, 13 January 2019
Line 3:		Line 3:
	[[Image:Ironsulfurferredoxin.png\|400px\|left\|thumb\| Ferredoxin NADP<sup>+</sup> Reductase zoomed in (4FK8)]]		[[Image:Ironsulfurferredoxin.png\|400px\|left\|thumb\| Ferredoxin NADP<sup>+</sup> Reductase zoomed in (4FK8)]]

-	<StructureSection load='4FK8' size='340' frame='true' side='right' caption='FNR protein' scene=''>	+	<StructureSection load='4FK8' size='340' frame='true' side='right' caption='FNR protein containg FAD (PDB code [[4fk8]])' scene=''>

Rebecca Truitt at 21:02, 14 May 2015

2015-05-14T21:02:49Z

←Older revision		Revision as of 21:02, 14 May 2015
Line 1:		Line 1:
		+	==Overview==
		+
	[[Image:Ironsulfurferredoxin.png\|400px\|left\|thumb\| Ferredoxin NADP<sup>+</sup> Reductase zoomed in (4FK8)]]		[[Image:Ironsulfurferredoxin.png\|400px\|left\|thumb\| Ferredoxin NADP<sup>+</sup> Reductase zoomed in (4FK8)]]

	<StructureSection load='4FK8' size='340' frame='true' side='right' caption='FNR protein' scene=''>		<StructureSection load='4FK8' size='340' frame='true' side='right' caption='FNR protein' scene=''>

-	==Overview==

	'''Ferredoxin NADP<sup>+</sup> reductase''' [http://en.wikipedia.org/wiki/Ferredoxin—NADP(%2B)_reductase] is an enzyme that catalyzes the reduction of NADP<sup>+</sup> to NADPH. This enzyme belongs to a family of enzymes called oxidoreductases[http://en.wikipedia.org/wiki/Oxidoreductase] that contain iron-sulfur proteins as electron donors and NAD<sup>+</sup> or NADP<sup>+</sup> as electron acceptors. FAD, [flavin adenine dinucleotide][http://en.wikipedia.org/wiki/Flavin_adenine_dinucleotide], is also a cofactor of FNR. The ferredoxin NADP<sup>+</sup> reductase participates in a general reaction that proceeds as follows:		'''Ferredoxin NADP<sup>+</sup> reductase''' [http://en.wikipedia.org/wiki/Ferredoxin—NADP(%2B)_reductase] is an enzyme that catalyzes the reduction of NADP<sup>+</sup> to NADPH. This enzyme belongs to a family of enzymes called oxidoreductases[http://en.wikipedia.org/wiki/Oxidoreductase] that contain iron-sulfur proteins as electron donors and NAD<sup>+</sup> or NADP<sup>+</sup> as electron acceptors. FAD, [flavin adenine dinucleotide][http://en.wikipedia.org/wiki/Flavin_adenine_dinucleotide], is also a cofactor of FNR. The ferredoxin NADP<sup>+</sup> reductase participates in a general reaction that proceeds as follows:

Rebecca Truitt at 20:59, 14 May 2015

2015-05-14T20:59:51Z

←Older revision		Revision as of 20:59, 14 May 2015
Line 1:		Line 1:
-	==Overview==
-
	[[Image:Ironsulfurferredoxin.png\|400px\|left\|thumb\| Ferredoxin NADP<sup>+</sup> Reductase zoomed in (4FK8)]]		[[Image:Ironsulfurferredoxin.png\|400px\|left\|thumb\| Ferredoxin NADP<sup>+</sup> Reductase zoomed in (4FK8)]]

-	<StructureSection load='4FK8' size='340' side='right' caption='FNR protein' scene=''>	+	<StructureSection load='4FK8' size='340' frame='true' side='right' caption='FNR protein' scene=''>
		+
		+	==Overview==

	'''Ferredoxin NADP<sup>+</sup> reductase''' [http://en.wikipedia.org/wiki/Ferredoxin—NADP(%2B)_reductase] is an enzyme that catalyzes the reduction of NADP<sup>+</sup> to NADPH. This enzyme belongs to a family of enzymes called oxidoreductases[http://en.wikipedia.org/wiki/Oxidoreductase] that contain iron-sulfur proteins as electron donors and NAD<sup>+</sup> or NADP<sup>+</sup> as electron acceptors. FAD, [flavin adenine dinucleotide][http://en.wikipedia.org/wiki/Flavin_adenine_dinucleotide], is also a cofactor of FNR. The ferredoxin NADP<sup>+</sup> reductase participates in a general reaction that proceeds as follows:		'''Ferredoxin NADP<sup>+</sup> reductase''' [http://en.wikipedia.org/wiki/Ferredoxin—NADP(%2B)_reductase] is an enzyme that catalyzes the reduction of NADP<sup>+</sup> to NADPH. This enzyme belongs to a family of enzymes called oxidoreductases[http://en.wikipedia.org/wiki/Oxidoreductase] that contain iron-sulfur proteins as electron donors and NAD<sup>+</sup> or NADP<sup>+</sup> as electron acceptors. FAD, [flavin adenine dinucleotide][http://en.wikipedia.org/wiki/Flavin_adenine_dinucleotide], is also a cofactor of FNR. The ferredoxin NADP<sup>+</sup> reductase participates in a general reaction that proceeds as follows: