General secretion pathway protein - Revision history

Michal Harel at 08:57, 2 August 2020

2020-08-02T08:57:20Z

←Older revision		Revision as of 08:57, 2 August 2020
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	[[General secretion pathway protein 3D structures]]		[[General secretion pathway protein 3D structures]]

-	==3D structures of general secretion pathway protein==
-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	*General secretion pathway protein AB
-
-	**[[4g54]] - VvEpsD residues 326-584 - ''Vibrio vulnificus''<br />
-
-	*General secretion pathway protein B
-
-	**[[4wfw]] - DdEpsB residues 112-201 - ''Dickeya dadantii''<br />
-
-	*General secretion pathway protein C
-
-	**[[2i4s]], [[2i6v]] - VcEpsC PDZ domain 204-305 - ''Vibrio cholerae''<br />
-	**[[2lnv]] - DdEpsC residues 77-172<br />
-
-	*General secretion pathway protein C+D+S
-
-	**[[6hcg]] - KpEpsC + EpsD + EpsS - ''Klebsiella pneumoniae'' - Cryo EM<br />
-
-	*General secretion pathway protein D
-
-	**[[6i1y]] - VvEpsD residues 121-673 - Cryo EM<br />
-	**[[3ezj]] - EpsD N-terminal 40-277 + nanobody - ''Eschericia coli''<br />
-	**[[4e9j]] - PaEpsD N-terminal 35-277 - ''Pseudomonas aeruginosa''<br />
-	**[[4ec5]] - PaEpsD N-terminal (mutant)<br />
-	**[[5wln]] - PaEpsD residues 35-658 - Cryo EM<br />
-	**[[6i1x]] - EpsD residues 122-645 - ''Aeromonas hydrophila'' - Cryo EM<br />
-
-	*General secretion pathway protein E
-
-	**[[1p9w]], [[1p9r]] - VcEpsE residues 1-90 <br />
-	**[[4ksr]], [[4kss]] - VcEpsE residues 100-503 <br />
-
-	*General secretion pathway protein E+L
-
-	**[[2bh1]] - VcEpsE residues 1-96 + VcEpsL residues 5-246<br />
-
-	*General secretion pathway protein F
-
-	**[[5nbg]] - DdEpsF residues 65-172<br />
-	**[[2vma]], [[2vmb]], [[3c1q]] - VcEpsF residues 56-170 <br />
-
-	*General secretion pathway protein L
-
-	**[[1yf5]], [[1w97]] - VcEpsL cytoplasmic domain 1-248 <br />
-	**[[2w7v]] - EpsL periplasmic domain 319-404 - ''Vibrio parahaemolyticus''<br />
-	**[[5n7l]] - PaEpsL periplasmic domain 303-382 <br />
-	**[[5hl8]] - KpEpsL C-terminal domain 309-397 <br />
-
-	*General secretion pathway protein M
-
-	**[[1uv7]] - VcEpsM periplasmic domain 65-165<br />
-
-	*General secretion pathway protein G,H,I,J,K see [[Pseudopilin]]
-	}}
	== References ==		== References ==
	<references/>		<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 08:54, 2 August 2020

2020-08-02T08:54:35Z

←Older revision		Revision as of 08:54, 2 August 2020
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	</SX>		</SX>
		+
		+	==3D structures of general secretion pathway protein==
		+	[[General secretion pathway protein 3D structures]]
		+
	==3D structures of general secretion pathway protein==		==3D structures of general secretion pathway protein==
	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

Jaime Prilusky at 07:25, 5 May 2020

2020-05-05T07:25:09Z

←Older revision		Revision as of 07:25, 5 May 2020
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-	<~~StructureSection~~ load='6hcg' size='340' side='right' caption='PulC + PulD + PulS complex (PDB code [[6hcg]])' scene=''>	+	<SX viewer='molstar' load='6hcg' size='340' side='right' caption='PulC + PulD + PulS complex (PDB code [[6hcg]])' scene=''>
-		+
	== Function ==		== Function ==

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-	</~~StructureSection~~>	+	</SX>
	==3D structures of general secretion pathway protein==		==3D structures of general secretion pathway protein==
	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

Michal Harel at 09:32, 1 May 2020

2020-05-01T09:32:24Z

←Older revision		Revision as of 09:32, 1 May 2020
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	'''General secretion pathway proteins''' (Eps) are used by gram-negative pathogenic bacteria to transport their virulence factors outside of the cell via '''type II secretion system''' or T2SS. Examples are the transport of cholera toxin by ''Vibrio cholerae'' and exotoxin A by ''Pseudomonas aeruginosa''<ref>PMID:26999395</ref>. In ''Pseudomonas aeruginosa'' the Eps are named Xcp. EpsG,H,I,J,K are named PulG, PulH, PulI, PulJ, PulK. See [[Pseudopilin]].		'''General secretion pathway proteins''' (Eps) are used by gram-negative pathogenic bacteria to transport their virulence factors outside of the cell via '''type II secretion system''' or T2SS. Examples are the transport of cholera toxin by ''Vibrio cholerae'' and exotoxin A by ''Pseudomonas aeruginosa''<ref>PMID:26999395</ref>. In ''Pseudomonas aeruginosa'' the Eps are named Xcp. EpsG,H,I,J,K are named PulG, PulH, PulI, PulJ, PulK. See [[Pseudopilin]].
-
-	== Disease ==
-
-	== Relevance ==

	== Structural highlights ==		== Structural highlights ==
		+
		+	The 3D structure of the bacterial core shows a 15-fold rotationally symmetric PulD called secretin which inserts into the cell membrane and enables conductance of substrate intothe external environment<ref>PMID:31780649</ref>.

Michal Harel at 09:15, 1 May 2020

2020-05-01T09:15:07Z

←Older revision		Revision as of 09:15, 1 May 2020
Line 1:		Line 1:
-	<StructureSection load='6hcg' size='340' side='right' caption='~~Caption for this structure~~' scene=''>	+	<StructureSection load='6hcg' size='340' side='right' caption='PulC + PulD + PulS complex (PDB code [[6hcg]])' scene=''>

	== Function ==		== Function ==

Michal Harel at 09:11, 1 May 2020

2020-05-01T09:11:48Z

←Older revision		Revision as of 09:11, 1 May 2020
Line 1:		Line 1:
-	<StructureSection load='~~4ksr~~' size='340' side='right' caption='Caption for this structure' scene=''>	+	<StructureSection load='6hcg' size='340' side='right' caption='Caption for this structure' scene=''>

	== Function ==		== Function ==

Michal Harel at 08:58, 1 May 2020

2020-05-01T08:58:26Z

←Older revision		Revision as of 08:58, 1 May 2020
Line 1:		Line 1:
-	<StructureSection load='~~1stp~~' size='340' side='right' caption='Caption for this structure' scene=''>	+	<StructureSection load='4ksr' size='340' side='right' caption='Caption for this structure' scene=''>
-	~~describing Jmol <ref>PMID:21638687</ref> to the rescue.~~	+

	== Function ==		== Function ==

-	'''General secretion pathway ~~protein~~''' (Eps)	+	'''General secretion pathway proteins''' (Eps) are used by gram-negative pathogenic bacteria to transport their virulence factors outside of the cell via '''type II secretion system''' or T2SS. Examples are the transport of cholera toxin by ''Vibrio cholerae'' and exotoxin A by ''Pseudomonas aeruginosa''<ref>PMID:26999395</ref>. In ''Pseudomonas aeruginosa'' the Eps are named Xcp. EpsG,H,I,J,K are named PulG, PulH, PulI, PulJ, PulK. See [[Pseudopilin]].
-		+
	== Disease ==		== Disease ==

Michal Harel at 08:15, 1 May 2020

2020-05-01T08:15:07Z

←Older revision		Revision as of 08:15, 1 May 2020
Line 12:		Line 12:
	== Structural highlights ==		== Structural highlights ==

-	cratch or loading and editing one of these sample scenes.

	</StructureSection>		</StructureSection>
	==3D structures of general secretion pathway protein==		==3D structures of general secretion pathway protein==
		+	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
		+	{{#tree:id=OrganizedByTopic\|openlevels=0\|
		+
		+	*General secretion pathway protein AB
		+
		+	**[[4g54]] - VvEpsD residues 326-584 - ''Vibrio vulnificus''<br />
		+
		+	*General secretion pathway protein B
		+
		+	**[[4wfw]] - DdEpsB residues 112-201 - ''Dickeya dadantii''<br />

	*General secretion pathway protein C		*General secretion pathway protein C

	**[[2i4s]], [[2i6v]] - VcEpsC PDZ domain 204-305 - ''Vibrio cholerae''<br />		**[[2i4s]], [[2i6v]] - VcEpsC PDZ domain 204-305 - ''Vibrio cholerae''<br />
		+	**[[2lnv]] - DdEpsC residues 77-172<br />
		+
		+	*General secretion pathway protein C+D+S
		+
		+	**[[6hcg]] - KpEpsC + EpsD + EpsS - ''Klebsiella pneumoniae'' - Cryo EM<br />
		+
		+	*General secretion pathway protein D
		+
		+	**[[6i1y]] - VvEpsD residues 121-673 - Cryo EM<br />
		+	**[[3ezj]] - EpsD N-terminal 40-277 + nanobody - ''Eschericia coli''<br />
		+	**[[4e9j]] - PaEpsD N-terminal 35-277 - ''Pseudomonas aeruginosa''<br />
		+	**[[4ec5]] - PaEpsD N-terminal (mutant)<br />
		+	**[[5wln]] - PaEpsD residues 35-658 - Cryo EM<br />
		+	**[[6i1x]] - EpsD residues 122-645 - ''Aeromonas hydrophila'' - Cryo EM<br />
		+
		+	*General secretion pathway protein E
		+
		+	**[[1p9w]], [[1p9r]] - VcEpsE residues 1-90 <br />
		+	**[[4ksr]], [[4kss]] - VcEpsE residues 100-503 <br />

	*General secretion pathway protein E+L		*General secretion pathway protein E+L
Line 27:		Line 55:
	*General secretion pathway protein F		*General secretion pathway protein F

-	**[[5nbg]] - ~~EpsF~~ residues 65-172 ~~- ''Dickeya dadantii''~~<br />	+	**[[5nbg]] - DdEpsF residues 65-172<br />
-	**[[2vma]] - VcEpsF residues 56-170 <br />	+	**[[2vma]], [[2vmb]], [[3c1q]] - VcEpsF residues 56-170 <br />

	*General secretion pathway protein L		*General secretion pathway protein L

	**[[1yf5]], [[1w97]] - VcEpsL cytoplasmic domain 1-248 <br />		**[[1yf5]], [[1w97]] - VcEpsL cytoplasmic domain 1-248 <br />
		+	**[[2w7v]] - EpsL periplasmic domain 319-404 - ''Vibrio parahaemolyticus''<br />
		+	**[[5n7l]] - PaEpsL periplasmic domain 303-382 <br />
		+	**[[5hl8]] - KpEpsL C-terminal domain 309-397 <br />

	*General secretion pathway protein M		*General secretion pathway protein M
Line 39:		Line 70:

	*General secretion pathway protein G,H,I,J,K see [[Pseudopilin]]		*General secretion pathway protein G,H,I,J,K see [[Pseudopilin]]
		+	}}
	== References ==		== References ==
	<references/>		<references/>
		+	[[Category:Topic Page]]

Michal Harel at 11:03, 30 April 2020

2020-04-30T11:03:15Z

←Older revision		Revision as of 11:03, 30 April 2020
Line 1:		Line 1:
-
	<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>		<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
	describing Jmol <ref>PMID:21638687</ref> to the rescue.		describing Jmol <ref>PMID:21638687</ref> to the rescue.
Line 30:		Line 29:
	**[[5nbg]] - EpsF residues 65-172 - ''Dickeya dadantii''<br />		**[[5nbg]] - EpsF residues 65-172 - ''Dickeya dadantii''<br />
	**[[2vma]] - VcEpsF residues 56-170 <br />		**[[2vma]] - VcEpsF residues 56-170 <br />
-
-	*General secretion pathway protein G
-
-	**[[5wda]] - KoEpsG residues 7-140 - ''Klebsiella oxytoca'' - Cryo EM<br />
-	**[[5o2y]] - KoEpsG residues 31-138 - NMR<br />
-	**[[2kep]] - PaEpsG residues 33-142 - ''Pseudomonas aeruginosa'' - NMR<br />
-	**[[1t92]] - EpsG residues 31-138 - ''Klebsiella pneumoniae'' - NMR<br />
-	**[[3fu1]] - VcEpsG residues 35-146<br />
-	**[[3gn9]] - EpsG residues 26-137 - ''Vibrio vulnificus''<br />
-
-	*General secretion pathway protein J+K+I
-
-	**[[5vtm]] - PaEpsJ residues 44-237 + PaEpsK residues 44-316 + PaEpsJ residues 38-129<br />

	*General secretion pathway protein L		*General secretion pathway protein L
Line 51:		Line 37:

	**[[1uv7]] - VcEpsM periplasmic domain 65-165<br />		**[[1uv7]] - VcEpsM periplasmic domain 65-165<br />
		+
		+	*General secretion pathway protein G,H,I,J,K see [[Pseudopilin]]
	== References ==		== References ==
	<references/>		<references/>

Michal Harel: New page: describing Jmol PMID:21638687 to the rescue. == Function == '''General se...

2020-04-30T07:40:55Z

New page: <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> describing Jmol <ref>PMID:21638687</ref> to the rescue. == Function == '''General se...

New page

<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
describing Jmol <ref>PMID:21638687</ref> to the rescue.

== Function ==

'''General secretion pathway protein''' (Eps)

== Disease ==

== Relevance ==

== Structural highlights ==

cratch or loading and editing one of these sample scenes.

</StructureSection>
==3D structures of general secretion pathway protein==

*General secretion pathway protein C

**[[2i4s]], [[2i6v]] - VcEpsC PDZ domain 204-305 - ''Vibrio cholerae'' 

*General secretion pathway protein E+L

**[[2bh1]] - VcEpsE residues 1-96 + VcEpsL residues 5-246 

*General secretion pathway protein F

**[[5nbg]] - EpsF residues 65-172 - ''Dickeya dadantii'' 
**[[2vma]] - VcEpsF residues 56-170 

*General secretion pathway protein G

**[[5wda]] - KoEpsG residues 7-140 - ''Klebsiella oxytoca'' - Cryo EM 
**[[5o2y]] - KoEpsG residues 31-138 - NMR 
**[[2kep]] - PaEpsG residues 33-142 - ''Pseudomonas aeruginosa'' - NMR 
**[[1t92]] - EpsG residues 31-138 - ''Klebsiella pneumoniae'' - NMR 
**[[3fu1]] - VcEpsG residues 35-146 
**[[3gn9]] - EpsG residues 26-137 - ''Vibrio vulnificus'' 

*General secretion pathway protein J+K+I

**[[5vtm]] - PaEpsJ residues 44-237 + PaEpsK residues 44-316 + PaEpsJ residues 38-129 

*General secretion pathway protein L

**[[1yf5]], [[1w97]] - VcEpsL cytoplasmic domain 1-248 

*General secretion pathway protein M

**[[1uv7]] - VcEpsM periplasmic domain 65-165 
== References ==
<references/>