Lotem haleva/test page - Revision history

http://52.214.119.220/wiki/index.php?action=history&feed=atom&title=Lotem_haleva%2Ftest_page Lotem haleva/test page - Revision history 2026-04-15T21:22:08Z Revision history for this page on the wiki MediaWiki 1.11.2 http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2705142&oldid=prev Michal Harel at 10:34, 9 January 2017 2017-01-09T10:34:15Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 10:34, 9 January 2017</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='1y3v' size='340' side='right' caption='Bovine trypsine complex with inhibitor and Ca+2 ion (green) (PDB code [[1y3v]])' scene=''></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='1y3v' size='340' side='right' caption='Bovine trypsine complex with inhibitor and Ca+2 ion (green) (PDB code [[1y3v]])' scene=''></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">'''</ins>Trypsin<ins style="color: red; font-weight: bold; text-decoration: none;">''' </ins>is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin Break peptide chains at the carboxyl side of the amino acids lysine or arginine, </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin Break peptide chains at the carboxyl side of the amino acids lysine or arginine, </div></td></tr> </table>

Michal Harel http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2572456&oldid=prev Michal Harel at 11:01, 11 February 2016 2016-02-11T11:01:41Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 11:01, 11 February 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='1y3v' size='340' side='right' caption='<del style="color: red; font-weight: bold; text-decoration: none;">Trysine</del>' scene=''></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='1y3v' size='340' side='right' caption='<ins style="color: red; font-weight: bold; text-decoration: none;">Bovine trypsine complex with inhibitor and Ca+2 ion (green) (PDB code [[1y3v]])</ins>' scene=''></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td></tr> </table>

Michal Harel http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2075881&oldid=prev Lotem Haleva at 08:27, 4 December 2014 2014-12-04T08:27:16Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 08:27, 4 December 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='<del style="color: red; font-weight: bold; text-decoration: none;">1ezg</del>' size='340' side='right' caption='Trysine' scene=''></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='<ins style="color: red; font-weight: bold; text-decoration: none;">1y3v</ins>' size='340' side='right' caption='Trysine' scene=''></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td></tr> </table>

Lotem Haleva http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2075880&oldid=prev Lotem Haleva at 08:24, 4 December 2014 2014-12-04T08:24:20Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 08:24, 4 December 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='<del style="color: red; font-weight: bold; text-decoration: none;">1l1i</del>' size='340' side='right' caption='Trysine' scene=''></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='<ins style="color: red; font-weight: bold; text-decoration: none;">1ezg</ins>' size='340' side='right' caption='Trysine' scene=''></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td></tr> </table>

Lotem Haleva http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2075879&oldid=prev Lotem Haleva at 08:23, 4 December 2014 2014-12-04T08:23:33Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 08:23, 4 December 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='<del style="color: red; font-weight: bold; text-decoration: none;">1y3v</del>' size='340' side='right' caption='Trysine' scene=''></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='<ins style="color: red; font-weight: bold; text-decoration: none;">1l1i</ins>' size='340' side='right' caption='Trysine' scene=''></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive zymogen protease called trypsinogen. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition. </div></td></tr> </table>

Lotem Haleva http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2066353&oldid=prev Lotem Haleva at 12:08, 23 November 2014 2014-11-23T12:08:16Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 12:08, 23 November 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 18:</td> <td colspan="2" class="diff-lineno">Line 18:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>There are different ways to present the protein structure<scene name='60/607865/Balls_and_stik/1'>balls and stick</scene> and <scene name='60/607865/Backbone/1'>Backbone</scene>.Another way to view the protein is <scene name='60/607865/Rainbow_n_to_c/1'>Rainbow</scene> that show the protein from the N (blue) to C terminal (green)</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>There are different ways to present the protein structure <ins style="color: red; font-weight: bold; text-decoration: none;">:</ins><scene name='60/607865/Balls_and_stik/1'>balls and stick<ins style="color: red; font-weight: bold; text-decoration: none;"></scene>, <scene name='60/607865/Surface/1'>surface</ins></scene> and <scene name='60/607865/Backbone/1'>Backbone</scene>. Another way to view the protein is <scene name='60/607865/Rainbow_n_to_c/1'>Rainbow</scene> that show the protein from the N (blue) to C terminal (green)<ins style="color: red; font-weight: bold; text-decoration: none;">.</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td></tr> </table>

Lotem Haleva http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2066349&oldid=prev Lotem Haleva at 12:02, 23 November 2014 2014-11-23T12:02:36Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 12:02, 23 November 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 2:</td> <td colspan="2" class="diff-lineno">Line 2:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='1y3v' size='340' side='right' caption='Trysine' scene=''></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='1y3v' size='340' side='right' caption='Trysine' scene=''></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a serine protease that found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive protease trypsinogen. </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive <ins style="color: red; font-weight: bold; text-decoration: none;">zymogen </ins>protease <ins style="color: red; font-weight: bold; text-decoration: none;">called </ins>trypsinogen<ins style="color: red; font-weight: bold; text-decoration: none;">. trypsinogen secreted into the small intestine where it activates trypsinogen into trypsin by the enzyme Antrookinaz using proteolytic decomposition</ins>. </div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin Break peptide chains at the carboxyl side of the amino acids lysine or arginine, </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin Break peptide chains at the carboxyl side of the amino acids lysine or arginine, </div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>except when it is followed by proline. .</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>except when it is followed by proline. .</div></td></tr> </table>

Lotem Haleva http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2066338&oldid=prev Lotem Haleva at 11:52, 23 November 2014 2014-11-23T11:52:41Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 11:52, 23 November 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 11:</td> <td colspan="2" class="diff-lineno">Line 11:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structure and Mechanism ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structure and Mechanism ==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a medium size globular protein that contains either <scene name='60/607865/Helix/1'>alpha helix</scene> and <scene name='60/607865/Sheets/1'>beta sheets</scene>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is a medium size globular protein that contains either <scene name='60/607865/Helix/1'>alpha helix</scene> and <scene name='60/607865/Sheets/1'>beta sheets</scene>.</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The enzymatic mechanism of Trypsin is similar to the other serine proteases. These enzymes contain a catalytic triad consisting of <scene name='60/607865/Active_site/2'>histidine-57, aspartate-102, and serine-195</scene>, These three residues <del style="color: red; font-weight: bold; text-decoration: none;">form a charge relay that serves to make </del>the active site serine nucleophilic <ref>doi:10.1007/s00018-005-5160-x</ref>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The enzymatic mechanism of Trypsin is similar to the other serine proteases. These enzymes contain a catalytic triad consisting of <scene name='60/607865/Active_site/2'>histidine-57, aspartate-102, and serine-195</scene>, These three residues <ins style="color: red; font-weight: bold; text-decoration: none;">makes </ins>the active site serine nucleophilic <ref>doi:10.1007/s00018-005-5160-x</ref>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin contains an "oxyanion hole" formed by the backbone amide hydrogen atoms of <scene name='60/607865/Oxyanion_hole/1'>Gly-193 and Ser-195</scene> , which serves to stabilize the developing negative charge on the carbonyl oxygen atom of the cleaved amides.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin contains an "oxyanion hole" formed by the backbone amide hydrogen atoms of <scene name='60/607865/Oxyanion_hole/1'>Gly-193 and Ser-195</scene> , which serves to stabilize the developing negative charge on the carbonyl oxygen atom of the cleaved amides.</div></td></tr> </table>

Lotem Haleva http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2066337&oldid=prev Lotem Haleva at 11:48, 23 November 2014 2014-11-23T11:48:06Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 11:48, 23 November 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Trypsin==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='1y3v' size='340' side='right' caption='Trysine' scene=''></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='1y3v' size='340' side='right' caption='Trysine' scene=''></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Trypsin is a serine protease<del style="color: red; font-weight: bold; text-decoration: none;">, </del>found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Trypsin is a serine protease <ins style="color: red; font-weight: bold; text-decoration: none;">that </ins>found in the digestive system of many vertebrates, where it hydrolyses proteins<ref>doi:10.1016/0076-6879(94)44004-2</ref>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive protease trypsinogen. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive protease trypsinogen. </div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Trypsin Break peptide chains <del style="color: red; font-weight: bold; text-decoration: none;">mainly </del>at the carboxyl side of the amino acids lysine or arginine, </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Trypsin Break peptide chains at the carboxyl side of the amino acids lysine or arginine, </div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>except when it is followed by proline. .</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>except when it is followed by proline. .</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2" class="diff-lineno">Line 10:</td> <td colspan="2" class="diff-lineno">Line 10:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structure and Mechanism ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structure and Mechanism ==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Trypsin is a medium size globular protein that contains either <scene name='60/607865/Helix/1'>alpha helix</scene> <del style="color: red; font-weight: bold; text-decoration: none;"> </del>and <scene name='60/607865/Sheets/1'>beta sheets</scene>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Trypsin is a medium size globular protein that contains either <scene name='60/607865/Helix/1'>alpha helix</scene> and <scene name='60/607865/Sheets/1'>beta sheets</scene>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The enzymatic mechanism of Trypsin is similar to the other serine proteases. These enzymes contain a catalytic triad consisting of <scene name='60/607865/Active_site/2'>histidine-57, aspartate-102, and serine-195</scene>, These three residues form a charge relay that serves to make the active site serine nucleophilic <ref>doi:10.1007/s00018-005-5160-x</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The enzymatic mechanism of Trypsin is similar to the other serine proteases. These enzymes contain a catalytic triad consisting of <scene name='60/607865/Active_site/2'>histidine-57, aspartate-102, and serine-195</scene>, These three residues form a charge relay that serves to make the active site serine nucleophilic <ref>doi:10.1007/s00018-005-5160-x</ref>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> </table>

Lotem Haleva http://52.214.119.220/wiki/index.php?title=Lotem_haleva/test_page&diff=2066334&oldid=prev Lotem Haleva at 11:39, 23 November 2014 2014-11-23T11:39:44Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 11:39, 23 November 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 4:</td> <td colspan="2" class="diff-lineno">Line 4:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive protease trypsinogen. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin is produced in the pancreas as the inactive protease trypsinogen. </div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin Break peptide chains mainly at the carboxyl side of the amino acids lysine or arginine, </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Trypsin Break peptide chains mainly at the carboxyl side of the amino acids lysine or arginine, </div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>except when <del style="color: red; font-weight: bold; text-decoration: none;">either </del>is followed by proline. <del style="color: red; font-weight: bold; text-decoration: none;">It is used for numerous biotechnological processes.</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>except when <ins style="color: red; font-weight: bold; text-decoration: none;">it </ins>is followed by proline. .</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">The process is commonly referred to as trypsin proteolysis or trypsinisation, </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">and proteins that have been digested/treated with trypsin are said to have been trypsinized</del>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Function ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Function ==</div></td></tr> <tr><td colspan="2" class="diff-lineno">Line 20:</td> <td colspan="2" class="diff-lineno">Line 18:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>There are different ways to present the protein structure<del style="color: red; font-weight: bold; text-decoration: none;">,</del><scene name='60/607865/Balls_and_stik/1'>balls and stick</scene> and <scene name='60/607865/Backbone/1'>Backbone</scene>.Another way to view the protein is <scene name='60/607865/Rainbow_n_to_c/1'>Rainbow</scene> that show the protein from the N (blue) to C terminal (green)</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>There are different ways to present the protein structure<scene name='60/607865/Balls_and_stik/1'>balls and stick</scene> and <scene name='60/607865/Backbone/1'>Backbone</scene>.Another way to view the protein is <scene name='60/607865/Rainbow_n_to_c/1'>Rainbow</scene> that show the protein from the N (blue) to C terminal (green)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td></tr> </table>

Lotem Haleva