Preprotein translocase - Revision history

Michal Harel at 07:33, 12 September 2023

2023-09-12T07:33:42Z

←Older revision		Revision as of 07:33, 12 September 2023
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	[[Preprotein translocase 3D structures]]		[[Preprotein translocase 3D structures]]

-	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-	{{#tree:id=OrganizedByTopic\|openlevels=0\|
-
-	*Preprotein translocase SecY + SecE + SecA
-
-	**[[6itc]] – BsPPT SecA + SecY + SecE + nanobody + GFP + translocating peptide – ''Bacillus subtilis'' – Cryo EM<br />
-
-	*Preprotein translocase SecY + SecE + SecB
-
-	**[[1rh5]], [[1rhz]] – MjPPT SecY + SecE + SecB – ''Methanocaldococcus jannaschii'' <br />
-
-	*Preprotein translocase SecY + SecE + SecG
-
-	**[[2akh]], [[2aki]] – EcPPT SecY + SecE + SecG – ''Escherichia coli'' - CryoEM <br />
-	**[[2yxq]], [[2yxr]] – MjPPT SecY + SecE + SecG <br />
-	**[[3dkn]] – PPT SecY + SecE + SecG + RNA – dog - CryoEM <br />
-	**[[3bo0]], [[3bo1]] – EcPPT SecY + SecE + SecG + 23S ribosomal RNA - CryoEM<br />
-	**[[4v7i]], [[3j45]], [[3j46]] – EcPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />
-	**[[4v4n]] – MjPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />
-
-	*Preprotein translocase SecY + SecG
-
-	**[[6r7l]] – EcPPT SecY + SecG - CryoEM <br />
-
-	*Preprotein translocase SecY + SecE
-
-	**[[3mp7]] – PPT SecY + SecE – ''Pyrococcus furiosus'' <br />
-	**[[2zjs]] – TtPPT SecY + SecE + antibody – ''Thermus thermophilus''<br />
-	**[[2zqp]] – TtPPT SecY + SecE <br />
-	**[[4v6m]] – EcPPT SecY + SecE + large ribosomal subunit - CryoEM<br />
-	**[[5abb]] – EcPPT SecY + SecE + green-light absorbing proteorhodopsin - CryoEM<br />
-
-	*Preprotein translocase SecY + SecE + SecG + SecA
-
-	**[[3din]] – TmPPT SecY + SecE + SecG + SecA – ''Thermotoga maritima''<br />
-	**[[3dl8]] – PPT SecY + SecE + SecA + SecG – ''Aquifex aeolicus'' - CryoEM<br />
-
-	*Preprotein translocase SecY + SecE + SecG + SecD + SecF
-
-	**[[5mg3]] – EcPPT SecY + SecE + SecG + SecD + SecF + YIDC - CryoEM<br />
-
-	*Preprotein translocase SecA
-
-	**[[1m6n]], [[1tf5]], [[2ibm]] – BsPPT SecA – ''Bacillus subtilis'' <br />
-	**[[3iqm]], [[3iqy]] – BsPPT SecA (mutant)<br />
-	**[[1tm6]] – EcPPT SecA C terminal - NMR<br />
-	**[[2ipc]] – TtPPT SecA<br />
-	**[[3jux]] – TmPPT SecA<br />
-	**[[2fsf]] – EcPPT SecA<br />
-	**[[2fsf]] – EcPPT SecA<br />
-	**[[3bxz]] – EcPPT SecA dead motor domains (mutant)<br />
-	**[[1nl3]] – MtPPT SecA – ''Mycobacterium tuberculosis''<br />
-
-	*Preprotein translocase SecA complex
-
-	**[[1m74]], [[1tf2]] – BsPPT SecA + Mg + ADP <br />
-	**[[1ozb]] – PPT SecA C terminal + SecB - ''Haemophilus influenzae''<br />
-	**[[2fsh]] – EcPPT SecA + AMPPNP<br />
-	**[[2fsi]] – EcPPT SecA + ADP<br />
-	**[[2fsg]] – EcPPT SecA + ATP<br />
-	**[[2vda]] – EcPPT SecA + maltoporin signal peptide - NMR<br />
-	**[[3jv2]] – BsPPT SecA + peptide <br />
-	**[[5eul]] – BsPPT SecA + SecE + SecY + AYC08 <br />
-	**[[1nkt]] – MtPPT SecA + ADP<br />
-	}}
	== References ==		== References ==
	<references/>		<references/>

Michal Harel at 07:29, 12 September 2023

2023-09-12T07:29:39Z

←Older revision		Revision as of 07:29, 12 September 2023
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	For more details see [[SecA PBD motions]].		For more details see [[SecA PBD motions]].
-	</StructureSection>

	==3D structures of preprotein translocase==		==3D structures of preprotein translocase==
		+
		+	[[Preprotein translocase 3D structures]]

	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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	== References ==		== References ==
	<references/>		<references/>
		+	</StructureSection>
		+
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 11:29, 31 January 2022

2022-01-31T11:29:06Z

←Older revision		Revision as of 11:29, 31 January 2022
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	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
	{{#tree:id=OrganizedByTopic\|openlevels=0\|		{{#tree:id=OrganizedByTopic\|openlevels=0\|
		+
		+	*Preprotein translocase SecY + SecE + SecA
		+
		+	**[[6itc]] – BsPPT SecA + SecY + SecE + nanobody + GFP + translocating peptide – ''Bacillus subtilis'' – Cryo EM<br />

	*Preprotein translocase SecY + SecE + SecB		*Preprotein translocase SecY + SecE + SecB
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	**[[4v7i]], [[3j45]], [[3j46]] – EcPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />		**[[4v7i]], [[3j45]], [[3j46]] – EcPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />
	**[[4v4n]] – MjPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />		**[[4v4n]] – MjPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />
		+
		+	*Preprotein translocase SecY + SecG
		+
		+	**[[6r7l]] – EcPPT SecY + SecG - CryoEM <br />

	*Preprotein translocase SecY + SecE		*Preprotein translocase SecY + SecE

Michal Harel at 10:07, 27 November 2017

2017-11-27T10:07:58Z

←Older revision		Revision as of 10:07, 27 November 2017
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	'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor<ref>PMID:9489663</ref>. The translocase pathway contains:<br />		'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor<ref>PMID:9489663</ref>. The translocase pathway contains:<br />
	*'''SecB''' - a chaperone protein<ref>PMID:9767586</ref> <br />		*'''SecB''' - a chaperone protein<ref>PMID:9767586</ref> <br />
-	*'''SecY, SecE, SecG''' an integral membrane complex<br />	+	*'''SecY, SecE, SecG''' or '''Sec61''' an integral membrane complex<br />
	*'''SecD, SecF''' - proteins promoting the release of the mature peptide into the periplasm<br />		*'''SecD, SecF''' - proteins promoting the release of the mature peptide into the periplasm<br />
	*'''SecA''' - an ATPase unit<ref>PMID:10617931</ref>.<br />		*'''SecA''' - an ATPase unit<ref>PMID:10617931</ref>.<br />

Michal Harel at 10:13, 14 September 2017

2017-09-14T10:13:56Z

←Older revision		Revision as of 10:13, 14 September 2017
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	**[[2zqp]] – TtPPT SecY + SecE <br />		**[[2zqp]] – TtPPT SecY + SecE <br />
	**[[4v6m]] – EcPPT SecY + SecE + large ribosomal subunit - CryoEM<br />		**[[4v6m]] – EcPPT SecY + SecE + large ribosomal subunit - CryoEM<br />
		+	**[[5abb]] – EcPPT SecY + SecE + green-light absorbing proteorhodopsin - CryoEM<br />

	*Preprotein translocase SecY + SecE + SecG + SecA		*Preprotein translocase SecY + SecE + SecG + SecA
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	**[[3din]] – TmPPT SecY + SecE + SecG + SecA – ''Thermotoga maritima''<br />		**[[3din]] – TmPPT SecY + SecE + SecG + SecA – ''Thermotoga maritima''<br />
	**[[3dl8]] – PPT SecY + SecE + SecA + SecG – ''Aquifex aeolicus'' - CryoEM<br />		**[[3dl8]] – PPT SecY + SecE + SecA + SecG – ''Aquifex aeolicus'' - CryoEM<br />
		+
		+	*Preprotein translocase SecY + SecE + SecG + SecD + SecF
		+
		+	**[[5mg3]] – EcPPT SecY + SecE + SecG + SecD + SecF + YIDC - CryoEM<br />

	*Preprotein translocase SecA		*Preprotein translocase SecA
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	**[[2vda]] – EcPPT SecA + maltoporin signal peptide - NMR<br />		**[[2vda]] – EcPPT SecA + maltoporin signal peptide - NMR<br />
	**[[3jv2]] – BsPPT SecA + peptide <br />		**[[3jv2]] – BsPPT SecA + peptide <br />
		+	**[[5eul]] – BsPPT SecA + SecE + SecY + AYC08 <br />
	**[[1nkt]] – MtPPT SecA + ADP<br />		**[[1nkt]] – MtPPT SecA + ADP<br />
	}}		}}

Michal Harel at 09:13, 20 November 2016

2016-11-20T09:13:53Z

←Older revision		Revision as of 09:13, 20 November 2016
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	**[[3dkn]] – PPT SecY + SecE + SecG + RNA – dog - CryoEM <br />		**[[3dkn]] – PPT SecY + SecE + SecG + RNA – dog - CryoEM <br />
	**[[3bo0]], [[3bo1]] – EcPPT SecY + SecE + SecG + 23S ribosomal RNA - CryoEM<br />		**[[3bo0]], [[3bo1]] – EcPPT SecY + SecE + SecG + 23S ribosomal RNA - CryoEM<br />
-	**[[~~3kcr~~]], [[3j45]], [[3j46]] – EcPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />	+	**[[4v7i]], [[3j45]], [[3j46]] – EcPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />
-	**[[~~1vvk~~]] – MjPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />	+	**[[4v4n]] – MjPPT SecY + SecE + SecG + large ribosomal subunit - CryoEM<br />

	*Preprotein translocase SecY + SecE		*Preprotein translocase SecY + SecE
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	**[[2zjs]] – TtPPT SecY + SecE + antibody – ''Thermus thermophilus''<br />		**[[2zjs]] – TtPPT SecY + SecE + antibody – ''Thermus thermophilus''<br />
	**[[2zqp]] – TtPPT SecY + SecE <br />		**[[2zqp]] – TtPPT SecY + SecE <br />
-	**[[~~3j01~~]] – EcPPT SecY + SecE + large ribosomal subunit - CryoEM<br />	+	**[[4v6m]] – EcPPT SecY + SecE + large ribosomal subunit - CryoEM<br />

	*Preprotein translocase SecY + SecE + SecG + SecA		*Preprotein translocase SecY + SecE + SecG + SecA

Michal Harel at 10:13, 11 July 2016

2016-07-11T10:13:34Z

←Older revision		Revision as of 10:13, 11 July 2016
Line 2:		Line 2:
	== Function ==		== Function ==
	'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor<ref>PMID:9489663</ref>. The translocase pathway contains:<br />		'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor<ref>PMID:9489663</ref>. The translocase pathway contains:<br />
-	*'''SecB''' - a chaperone protein <br />	+	*'''SecB''' - a chaperone protein<ref>PMID:9767586</ref> <br />
	*'''SecY, SecE, SecG''' an integral membrane complex<br />		*'''SecY, SecE, SecG''' an integral membrane complex<br />
	*'''SecD, SecF''' - proteins promoting the release of the mature peptide into the periplasm<br />		*'''SecD, SecF''' - proteins promoting the release of the mature peptide into the periplasm<br />
-	*'''SecA''' - an ATPase unit.<br />	+	*'''SecA''' - an ATPase unit<ref>PMID:10617931</ref>.<br />

	For more details see [[SecA PBD motions]].		For more details see [[SecA PBD motions]].

Michal Harel at 10:08, 11 July 2016

2016-07-11T10:08:41Z

←Older revision		Revision as of 10:08, 11 July 2016
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	<StructureSection load='2yxr' size='350' side='right' caption='Structure of preprotein translocase subunits SecY (grey), SecE (green), SecG (pink) (PDB entry [[2yxr]])' scene=''>		<StructureSection load='2yxr' size='350' side='right' caption='Structure of preprotein translocase subunits SecY (grey), SecE (green), SecG (pink) (PDB entry [[2yxr]])' scene=''>
	== Function ==		== Function ==
-	'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor. The translocase pathway contains a chaperone protein – '''~~SecB~~'''; an integral membrane complex – '''~~SecY~~, ~~SecE, SecG;~~''' proteins promoting the release of the mature peptide into the periplasm – '''~~SecD, SecF~~'''~~; and~~ ATPase unit ~~- '''SecA'''<ref>PMID:9489663~~</~~ref~~>. For more details see [[SecA PBD motions]].	+	'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor<ref>PMID:9489663</ref>. The translocase pathway contains:<br />
		+	*'''SecB''' - a chaperone protein <br />
		+	*'''SecY, SecE, SecG''' an integral membrane complex<br />
		+	*'''SecD, SecF''' - proteins promoting the release of the mature peptide into the periplasm<br />
		+	*'''SecA''' - an ATPase unit.<br />
		+
		+	For more details see [[SecA PBD motions]].
	</StructureSection>		</StructureSection>

Michal Harel at 09:58, 11 July 2016

2016-07-11T09:58:18Z

←Older revision		Revision as of 09:58, 11 July 2016
Line 1:		Line 1:
	<StructureSection load='2yxr' size='350' side='right' caption='Structure of preprotein translocase subunits SecY (grey), SecE (green), SecG (pink) (PDB entry [[2yxr]])' scene=''>		<StructureSection load='2yxr' size='350' side='right' caption='Structure of preprotein translocase subunits SecY (grey), SecE (green), SecG (pink) (PDB entry [[2yxr]])' scene=''>
-		+	== Function ==
-	'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor. The translocase pathway contains a chaperone protein – '''SecB'''; an integral membrane complex – '''SecY, SecE, SecG;''' proteins promoting the release of the mature peptide into the periplasm – '''SecD, SecF'''; and ATPase unit - '''SecA'''. For more details see [[SecA PBD motions]].	+	'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor. The translocase pathway contains a chaperone protein – '''SecB'''; an integral membrane complex – '''SecY, SecE, SecG;''' proteins promoting the release of the mature peptide into the periplasm – '''SecD, SecF'''; and ATPase unit - '''SecA'''<ref>PMID:9489663</ref>. For more details see [[SecA PBD motions]].
	</StructureSection>		</StructureSection>

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	**[[1nkt]] – MtPPT SecA + ADP<br />		**[[1nkt]] – MtPPT SecA + ADP<br />
	}}		}}
		+	== References ==
		+	<references/>
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 10:25, 4 December 2014

2014-12-04T10:25:37Z

←Older revision		Revision as of 10:25, 4 December 2014
Line 2:		Line 2:

	'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor. The translocase pathway contains a chaperone protein – '''SecB'''; an integral membrane complex – '''SecY, SecE, SecG;''' proteins promoting the release of the mature peptide into the periplasm – '''SecD, SecF'''; and ATPase unit - '''SecA'''. For more details see [[SecA PBD motions]].		'''Preprotein translocase''' (PPT) is responsible for the recognition and membrane translocation of preproteins. PPT contains receptors and import motor. The translocase pathway contains a chaperone protein – '''SecB'''; an integral membrane complex – '''SecY, SecE, SecG;''' proteins promoting the release of the mature peptide into the periplasm – '''SecD, SecF'''; and ATPase unit - '''SecA'''. For more details see [[SecA PBD motions]].
		+	</StructureSection>

	==3D structures of preprotein translocase==		==3D structures of preprotein translocase==