Spectrin 3D structures - Revision history

Michal Harel at 11:12, 21 November 2023

2023-11-21T11:12:29Z

←Older revision		Revision as of 11:12, 21 November 2023
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	**[[3fb2]] – hSPT a2 chain repeats 15-16 1337-1544<br />		**[[3fb2]] – hSPT a2 chain repeats 15-16 1337-1544<br />
	**[[5fw9]], [[5fwb]], [[5fwc]], [[5ihi]], [[5ihk]], [[5ihn]] – hSPT a2 chain SH3 domain (mutant)<br />		**[[5fw9]], [[5fwb]], [[5fwc]], [[5ihi]], [[5ihk]], [[5ihn]] – hSPT a2 chain SH3 domain (mutant)<br />
		+	**[[8cf4]], [[8chg]], [[8chh]] – cSPTA2 SH3 domain 965-1025 – NMR<br />
	**[[2fot]] - SPT a2 chain calmodulin-binding domain 1172-1211 +calmodulin – bovine<br />		**[[2fot]] - SPT a2 chain calmodulin-binding domain 1172-1211 +calmodulin – bovine<br />
	**[[3thk]] - SPT a2 chain SH3 domain + polypeptide - rat		**[[3thk]] - SPT a2 chain SH3 domain + polypeptide - rat
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	**[[1bkr]], [[1aa2]] – hSPT β chain 2nd CH domain 178-291<br />		**[[1bkr]], [[1aa2]] – hSPT β chain 2nd CH domain 178-291<br />
		+	**[[8iah]], [[8iai]], [[8ib2]] – pSPTB in spectrin-actin junction complex – Cryo EM<br />
	**[[1dro]], [[1mph]] - mSPT β chain PH domain 2199-2304 – NMR – mouse<br />		**[[1dro]], [[1mph]] - mSPT β chain PH domain 2199-2304 – NMR – mouse<br />
	**[[1btn]] – mSPT β chain PH domain + inositol phosphate<br />		**[[1btn]] – mSPT β chain PH domain + inositol phosphate<br />

Michal Harel at 10:15, 7 April 2022

2022-04-07T10:15:47Z

←Older revision		Revision as of 10:15, 7 April 2022
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	**[[1owa]] - hSPT a chain N-terminal tetramerization domain – NMR<br />		**[[1owa]] - hSPT a chain N-terminal tetramerization domain – NMR<br />
	**[[5j4o]] - hSPT a chain repeats 16-17 1599-1826<br />		**[[5j4o]] - hSPT a chain repeats 16-17 1599-1826<br />
		+	**[[2fot]] - SPTA2+calmodulin – bovine<br />
		+	**[[6scw]] - pSPTA SH3 subunit – pig – NMR<br />
		+	**[[7s4r]] - cSPTA SH3 domain<br />
	**[[2kr3]], [[4f17]], [[4f16]] - cSPT a chain SH3 domain<br />		**[[2kr3]], [[4f17]], [[4f16]] - cSPT a chain SH3 domain<br />
	**[[1e6g]], [[1e6h]], [[1hd3]], [[1qkx]], [[1pwt]], [[1bk2]], [[1shg]], [[1h8k]], [[3ngp]], [[3m0p]], [[3m0q]], [[3m0r]], [[3m0s]], [[3m0t]], [[3m0u]] - cSPT a chain SH3 domain (mutant)<br />		**[[1e6g]], [[1e6h]], [[1hd3]], [[1qkx]], [[1pwt]], [[1bk2]], [[1shg]], [[1h8k]], [[3ngp]], [[3m0p]], [[3m0q]], [[3m0r]], [[3m0s]], [[3m0t]], [[3m0u]] - cSPT a chain SH3 domain (mutant)<br />
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	**[[1cun]] - cSPT a chain repeats 16-17 (mutant) 1771-1982<br />		**[[1cun]] - cSPT a chain repeats 16-17 (mutant) 1771-1982<br />
	**[[1aj3]] - cSPT a chain repeat 16 1772-1869 - NMR<br />		**[[1aj3]] - cSPT a chain repeat 16 1772-1869 - NMR<br />
-	**[[6ro9]] – SPT SH3 domain – sunfish<br />	+	**[[6ro9]] – SPT SH3 domain (mutant) – sunfish<br />

	* Spectrin β1		* Spectrin β1
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	* Spectrin β2		* Spectrin β2

-	**[[3edv]] – hSPT β2 chain repeats 14-16 1697-2015	+	**[[3edv]] – hSPT β2 chain repeats 14-16 1697-2015<br />
		+	**[[6m3p]] – mSPTB2 + Ankyrin-3 - mouse<br />

	* Spectrin β3		* Spectrin β3
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	**[[1wyq]] – hSPT β3 chain 2nd CH domain – NMR<br />		**[[1wyq]] – hSPT β3 chain 2nd CH domain – NMR<br />
	**[[1wjm]] – hSPT β3 chain PH domain 2199-2328 – NMR<br />		**[[1wjm]] – hSPT β3 chain PH domain 2199-2328 – NMR<br />
-	**[[6anu]] - hSPT β3 chain actin binding domain 1-284 + actin - Cryo EM<br />	+	**[[6anu]] - hSPT β3 chain actin binding domain 1-284 (mutant) + actin - Cryo EM<br />

	* Spectrin β4		* Spectrin β4

Michal Harel: New page: == 3D Structures of Spectrin == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| * Spectrin α1; Domains – N-termi...

2022-04-07T09:38:04Z

New page: == 3D Structures of Spectrin == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| * Spectrin α1; Domains – N-termi...

New page

== 3D Structures of Spectrin ==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

* Spectrin α1; Domains – N-terminal tetramerization 1-156; SH3 969-1025; C-terminal tetramerization 1902-2084

**[[3lbx]] – hSPT a chain N-terminal tetramerization domain +hSPT b chain C-terminal tetramerization domain – human 
**[[2rot]], [[2oaw]], [[2nuz]], [[1u06]] - cSPT a chain SH3 domain – chicken 
**[[2jm8]], [[2jm9]], [[2cdt]], [[2f2v]], [[2f2w]], [[2f2x]], [[3i9q]] - cSPT a chain SH3 domain (mutant) 
**[[2rmo]], [[1neg]], [[1m8m]] - cSPT a chain SH3 domain – NMR 
**[[2jma]], [[2jmc]] - cSPT a chain SH3 domain (mutant)+P41 peptide 

* Spectrin α2

**[[3f31]] – hSPT a2 chain N-terminal tetramerization domain 
**[[5fwc]], [[5fwb]] - hSPT a2 chain SH3 domain (mutant) 
**[[3fb2]] – hSPT a2 chain repeats 15-16 1337-1544 
**[[5fw9]], [[5fwb]], [[5fwc]], [[5ihi]], [[5ihk]], [[5ihn]] – hSPT a2 chain SH3 domain (mutant) 
**[[2fot]] - SPT a2 chain calmodulin-binding domain 1172-1211 +calmodulin – bovine 
**[[3thk]] - SPT a2 chain SH3 domain + polypeptide - rat
**[[1qkw]] – cSPT a2 chain SH3 domain (mutant) 

* Spectrin α

**[[1owa]] - hSPT a chain N-terminal tetramerization domain – NMR 
**[[5j4o]] - hSPT a chain repeats 16-17 1599-1826 
**[[2kr3]], [[4f17]], [[4f16]] - cSPT a chain SH3 domain 
**[[1e6g]], [[1e6h]], [[1hd3]], [[1qkx]], [[1pwt]], [[1bk2]], [[1shg]], [[1h8k]], [[3ngp]], [[3m0p]], [[3m0q]], [[3m0r]], [[3m0s]], [[3m0t]], [[3m0u]] - cSPT a chain SH3 domain (mutant) 
**[[1uue]], [[1e7o]], [[1g2b]], [[1aey]], [[1tuc]], [[1tud]] - cSPT a chain SH3 domain (mutant) – NMR 
**[[2lj3]], [[6scw]] - cSPT a chain SH3 domain – NMR 
**[[1u4q]] – cSPT a chain repeats 15-17 1662-1982 
**[[1u5p]] - cSPT a chain repeats 15-16 1662-1876 
**[[1cun]] - cSPT a chain repeats 16-17 (mutant) 1771-1982 
**[[1aj3]] - cSPT a chain repeat 16 1772-1869 - NMR 
**[[6ro9]] – SPT SH3 domain – sunfish 

* Spectrin β1

**[[3kbt]], [[3kbu]] - hSPT β1 chain repeats 13-15 1583-1906 +ankyrin 
**[[3f57]], [[3edu]] - hSPT β1 chain repeats 14-15 1686-1906 
**[[1s35]] – hSPT β1 chain repeats 8-9 1063-1275 (mutant)

* Spectrin β2

**[[3edv]] – hSPT β2 chain repeats 14-16 1697-2015

* Spectrin β3

**[[1wyq]] – hSPT β3 chain 2nd CH domain – NMR 
**[[1wjm]] – hSPT β3 chain PH domain 2199-2328 – NMR 
**[[6anu]] - hSPT β3 chain actin binding domain 1-284 + actin - Cryo EM 

* Spectrin β4

**[[6m3r]] – mSPT b chain 1616-1937 + Ankyrin-3 
**[[6m3q]] – mSPT b chain + Ankyrin-2 

* Spectrin β

**[[1bkr]], [[1aa2]] – hSPT β chain 2nd CH domain 178-291 
**[[1dro]], [[1mph]] - mSPT β chain PH domain 2199-2304 – NMR – mouse 
**[[1btn]] – mSPT β chain PH domain + inositol phosphate 
**[[6m3p]] – mSPT β 2 chain 1591-1910 + Ankyrin-3 
**[[2spc]] – SPT fragment 1391-1497 - ''Drosophila melanogaster''

* Spectrin R16

**[[5m6s]] – SPT - ''Escherichia coli'' 

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