User:Jiaming Zhuang/Sandbox 2 - Revision history

http://52.214.119.220/wiki/index.php?action=history&feed=atom&title=User%3AJiaming_Zhuang%2FSandbox_2 User:Jiaming Zhuang/Sandbox 2 - Revision history 2026-04-10T19:27:13Z Revision history for this page on the wiki MediaWiki 1.11.2 http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=2102825&oldid=prev Mallory Gordon at 00:58, 11 December 2014 2014-12-11T00:58:40Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 00:58, 11 December 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 4:</td> <td colspan="2" class="diff-lineno">Line 4:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">This is </del>the <scene name='40/400553/Pro_cat_motif/4'>active site</scene> <del style="color: red; font-weight: bold; text-decoration: none;">of </del>the <del style="color: red; font-weight: bold; text-decoration: none;">protein</del>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">ProMMP9 has a propeptide domain with a zinc ligating "cysteine switch" at </ins>the <scene name='40/400553/Pro_cat_motif/4'>active site</scene><ins style="color: red; font-weight: bold; text-decoration: none;">, rendering </ins>the <ins style="color: red; font-weight: bold; text-decoration: none;">enzyme inactive until the propeptide is cleaved</ins>. </div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> </table>

Mallory Gordon http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=2102824&oldid=prev Mallory Gordon at 00:47, 11 December 2014 2014-12-11T00:47:23Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 00:47, 11 December 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 4:</td> <td colspan="2" class="diff-lineno">Line 4:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><<del style="color: red; font-weight: bold; text-decoration: none;">Structure load='1L6J' size='350' frame='true' align='right' caption='MMP-9 (from PDB entry 1L6J)' </del>scene='<del style="color: red; font-weight: bold; text-decoration: none;">scene 1</del>' /></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">This is the </ins><scene <ins style="color: red; font-weight: bold; text-decoration: none;">name</ins>='<ins style="color: red; font-weight: bold; text-decoration: none;">40/400553/Pro_cat_motif/4</ins>'<ins style="color: red; font-weight: bold; text-decoration: none;">>active site<</ins>/<ins style="color: red; font-weight: bold; text-decoration: none;">scene</ins>> <ins style="color: red; font-weight: bold; text-decoration: none;">of the protein.</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> </table>

Mallory Gordon http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=2102822&oldid=prev Mallory Gordon at 00:30, 11 December 2014 2014-12-11T00:30:15Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 00:30, 11 December 2014</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 4:</td> <td colspan="2" class="diff-lineno">Line 4:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><Structure load='1L6J' size='350' frame='true' align='right' caption='MMP-9 (from PDB entry 1L6J)' scene='scene 1' /></ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> </table>

Mallory Gordon http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=1639679&oldid=prev Jiaming Zhuang at 02:37, 21 December 2012 2012-12-21T02:37:04Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 02:37, 21 December 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 12:</td> <td colspan="2" class="diff-lineno">Line 12:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Reference:</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Reference:</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Siân Rowsell, Paul Hawtin,Claire A. Minshull, Holly Jepson, Sarah M.V. Brockbank,Derek G. Barratt, Anthony M. Slater, William L. McPheat, David Waterson, Adriano M. Henney, Richard A. Pauptit Crystal Structure of Human MMP9 in Complex with a Reverse Hydroxamate Inhibitor, Volume 319, Issue 1, 24 May 2002, Pages 173–181</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Siân Rowsell, Paul Hawtin,Claire A. Minshull, Holly Jepson, Sarah M.V. Brockbank,Derek G. Barratt, Anthony M. Slater, William L. McPheat, David Waterson, Adriano M. Henney, Richard A. Pauptit Crystal Structure of Human MMP9 in Complex with a Reverse Hydroxamate Inhibitor, Volume 319, Issue 1, 24 May 2002, Pages 173–181</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>----</div></td></tr> </table>

Jiaming Zhuang http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=1639678&oldid=prev Jiaming Zhuang at 02:36, 21 December 2012 2012-12-21T02:36:29Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 02:36, 21 December 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 2:</td> <td colspan="2" class="diff-lineno">Line 2:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of <scene name='User:Jiaming_Zhuang/Sandbox_2/Ligand/1'>inhibitors</scene> have been designed to bind to the <scene name='User:Jiaming_Zhuang/Sandbox_2/Domain1/1'>catalytic domain</scene> and inhibit the activity of MMP9.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of <scene name='User:Jiaming_Zhuang/Sandbox_2/Ligand/1'>inhibitors</scene> have been designed to bind to the <scene name='User:Jiaming_Zhuang/Sandbox_2/Domain1/1'>catalytic domain</scene> and inhibit the activity of MMP9.</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>----</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Reference:</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Siân Rowsell, Paul Hawtin,Claire A. Minshull, Holly Jepson, Sarah M.V. Brockbank,Derek G. Barratt, Anthony M. Slater, William L. McPheat, David Waterson, Adriano M. Henney, Richard A. Pauptit Crystal Structure of Human MMP9 in Complex with a Reverse Hydroxamate Inhibitor, Volume 319, Issue 1, 24 May 2002, Pages 173–181</div></td></tr> </table>

Jiaming Zhuang http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=1639677&oldid=prev Jiaming Zhuang at 02:33, 21 December 2012 2012-12-21T02:33:09Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 02:33, 21 December 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><Structure load='1gkc' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><Structure load='1gkc' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of <scene name='User:Jiaming_Zhuang/Sandbox_2/Ligand/1'>inhibitors</scene> have been designed to bind to the <scene name='User:Jiaming_Zhuang/Sandbox_2/<del style="color: red; font-weight: bold; text-decoration: none;">Domain</del>/1'>catalytic domain</scene> and inhibit the activity of MMP9.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of <scene name='User:Jiaming_Zhuang/Sandbox_2/Ligand/1'>inhibitors</scene> have been designed to bind to the <scene name='User:Jiaming_Zhuang/Sandbox_2/<ins style="color: red; font-weight: bold; text-decoration: none;">Domain1</ins>/1'>catalytic domain</scene> and inhibit the activity of MMP9.</div></td></tr> </table>

Jiaming Zhuang http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=1639676&oldid=prev Jiaming Zhuang at 02:28, 21 December 2012 2012-12-21T02:28:40Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 02:28, 21 December 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><Structure load='1gkc' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><Structure load='1gkc' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of <scene name='User:Jiaming_Zhuang/Sandbox_2/Ligand/1'>inhibitors</scene> have been designed to bind to the <del style="color: red; font-weight: bold; text-decoration: none;">[[</del>catalytic domain<del style="color: red; font-weight: bold; text-decoration: none;">]] </del>and inhibit the activity of MMP9.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of <scene name='User:Jiaming_Zhuang/Sandbox_2/Ligand/1'>inhibitors</scene> have been designed to bind to the <ins style="color: red; font-weight: bold; text-decoration: none;"><scene name='User:Jiaming_Zhuang/Sandbox_2/Domain/1'></ins>catalytic domain<ins style="color: red; font-weight: bold; text-decoration: none;"></scene> </ins>and inhibit the activity of MMP9.</div></td></tr> </table>

Jiaming Zhuang http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=1639673&oldid=prev Jiaming Zhuang at 02:02, 21 December 2012 2012-12-21T02:02:01Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 02:02, 21 December 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><Structure load='1gkc' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><Structure load='1gkc' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of <del style="color: red; font-weight: bold; text-decoration: none;">[[</del>inhibitors<del style="color: red; font-weight: bold; text-decoration: none;">]] </del>have been designed to bind to the [[catalytic domain]] and inhibit the activity of MMP9.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of <ins style="color: red; font-weight: bold; text-decoration: none;"><scene name='User:Jiaming_Zhuang/Sandbox_2/Ligand/1'></ins>inhibitors<ins style="color: red; font-weight: bold; text-decoration: none;"></scene> </ins>have been designed to bind to the [[catalytic domain]] and inhibit the activity of MMP9.</div></td></tr> </table>

Jiaming Zhuang http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=1639665&oldid=prev Jiaming Zhuang at 00:13, 21 December 2012 2012-12-21T00:13:30Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 00:13, 21 December 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><Structure load='<del style="color: red; font-weight: bold; text-decoration: none;">1L6J</del>' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><Structure load='<ins style="color: red; font-weight: bold; text-decoration: none;">1gkc</ins>' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of [[inhibitors]] have been designed to bind to the [[catalytic domain]] and inhibit the activity of MMP9.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target. Various of [[inhibitors]] have been designed to bind to the [[catalytic domain]] and inhibit the activity of MMP9.</div></td></tr> </table>

Jiaming Zhuang http://52.214.119.220/wiki/index.php?title=User:Jiaming_Zhuang/Sandbox_2&diff=1639631&oldid=prev Jiaming Zhuang at 18:04, 20 December 2012 2012-12-20T18:04:22Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 18:04, 20 December 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><Structure load='1L6J' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><Structure load='1L6J' size='400' frame='true' align='right' caption='MMP9' scene='Insert optional scene name here' /></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>MMP9 is a member of ''' matrix metalloproteinases''' (MMPs) which are zinc-dependent endopeptidases. It has been found to associate with many types of cancers and investigated as a potential drug target<ins style="color: red; font-weight: bold; text-decoration: none;">. Various of [[inhibitors]] have been designed to bind to the [[catalytic domain]] and inhibit the activity of MMP9</ins>.</div></td></tr> </table>

Jiaming Zhuang