User:John S. de Banzie/Sandbox 4 - Revision history

http://52.214.119.220/wiki/index.php?action=history&feed=atom&title=User%3AJohn_S._de_Banzie%2FSandbox_4 User:John S. de Banzie/Sandbox 4 - Revision history 2026-04-12T18:11:52Z Revision history for this page on the wiki MediaWiki 1.11.2 http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2583004&oldid=prev John S. de Banzie at 16:21, 18 March 2016 2016-03-18T16:21:26Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 16:21, 18 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 5:</td> <td colspan="2" class="diff-lineno">Line 5:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Focusing <scene name='72/726441/Rnascene/1'>on the RNAs</scene> reveals secondary structure and extensive base pairing between the U4 and U6 snRNAs.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Focusing <scene name='72/726441/Rnascene/1'>on the RNAs</scene> reveals secondary structure and extensive base pairing between the U4 and U6 snRNAs.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The U2 snRNP <scene name='72/726441/Dockscene/1'><del style="color: red; font-weight: bold; text-decoration: none;">binds to the region</del></scene> <del style="color: red; font-weight: bold; text-decoration: none;">highlighted in blue in this view</del>. The U1 snRNP <del style="color: red; font-weight: bold; text-decoration: none;">binds to </del>the U2 snRNP. <del style="color: red; font-weight: bold; text-decoration: none;">Both interactions lead to </del>extensive conformational <del style="color: red; font-weight: bold; text-decoration: none;">change and </del>activation of the spliceosome.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The <ins style="color: red; font-weight: bold; text-decoration: none;">spliceosome is assembled from the U4/U6.U5 tri-snRNP, the U1 snRNP, and the </ins>U2 snRNP<ins style="color: red; font-weight: bold; text-decoration: none;">. The U2 snRNP interacts with the region highlighted in blue </ins><scene name='72/726441/Dockscene/1'><ins style="color: red; font-weight: bold; text-decoration: none;">in this view</ins></scene>. The U1 snRNP <ins style="color: red; font-weight: bold; text-decoration: none;">interacts with </ins>the U2 snRNP. <ins style="color: red; font-weight: bold; text-decoration: none;">The initial assembly is inactive; </ins>extensive conformational <ins style="color: red; font-weight: bold; text-decoration: none;">changes (including unwinding of the U4/U6 base pairing) are required for </ins>activation of the spliceosome.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td></tr> </table>

John S. de Banzie http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2582999&oldid=prev John S. de Banzie at 15:29, 18 March 2016 2016-03-18T15:29:18Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 15:29, 18 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The <scene name='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6).</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The <scene name='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4<ins style="color: red; font-weight: bold; text-decoration: none;">: orange</ins>, U5<ins style="color: red; font-weight: bold; text-decoration: none;">: red</ins>, and U6<ins style="color: red; font-weight: bold; text-decoration: none;">: purple</ins>).</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Focusing <scene name='72/726441/Rnascene/1'>on the RNAs</scene> reveals secondary structure and extensive base pairing between the U4 and U6 snRNAs.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Focusing <scene name='72/726441/Rnascene/1'>on the RNAs</scene> reveals secondary structure and extensive base pairing between the U4 and U6 snRNAs.</div></td></tr> </table>

John S. de Banzie http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2582997&oldid=prev John S. de Banzie at 15:26, 18 March 2016 2016-03-18T15:26:11Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 15:26, 18 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 3:</td> <td colspan="2" class="diff-lineno">Line 3:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The <scene name='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6).</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The <scene name='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6).</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Focusing <scene name='72/726441/Rnascene/1'>on the RNAs</scene> reveals extensive base pairing between the U4 and U6 snRNAs.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Focusing <scene name='72/726441/Rnascene/1'>on the RNAs</scene> reveals <ins style="color: red; font-weight: bold; text-decoration: none;">secondary structure and </ins>extensive base pairing between the U4 and U6 snRNAs.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The U2 snRNP <scene name='72/726441/Dockscene/1'>binds to the region </scene>highlighted in blue in this view. The U1 snRNP binds to the <del style="color: red; font-weight: bold; text-decoration: none;">U2snRNP</del>. Both interactions lead to extensive conformational change and activation of the spliceosome.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The U2 snRNP <scene name='72/726441/Dockscene/1'>binds to the region</scene> highlighted in blue in this view. The U1 snRNP binds to the <ins style="color: red; font-weight: bold; text-decoration: none;">U2 snRNP</ins>. Both interactions lead to extensive conformational change and activation of the spliceosome.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.</div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== References ==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><references/></div></td></tr> </table>

John S. de Banzie http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2582996&oldid=prev John S. de Banzie at 15:23, 18 March 2016 2016-03-18T15:23:03Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 15:23, 18 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The <scene='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6).</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The <scene <ins style="color: red; font-weight: bold; text-decoration: none;">name</ins>='72/726441/Firstscene/2'>initial view</scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6).</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><scene='72/726441/Rnascene/1'><del style="color: red; font-weight: bold; text-decoration: none;">Focusing </del>on the RNAs</scene> reveals extensive base pairing between the U4 and U6 snRNAs.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">Focusing </ins><scene <ins style="color: red; font-weight: bold; text-decoration: none;">name</ins>='72/726441/Rnascene/1'>on the RNAs</scene> reveals extensive base pairing between the U4 and U6 snRNAs.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The U2 snRNP binds to the region highlighted in blue in this view. The U1 snRNP binds to the U2snRNP. Both interactions lead to extensive conformational change and activation of the spliceosome.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The U2 snRNP <ins style="color: red; font-weight: bold; text-decoration: none;"><scene name='72/726441/Dockscene/1'></ins>binds to the region <ins style="color: red; font-weight: bold; text-decoration: none;"></scene></ins>highlighted in blue in this view. The U1 snRNP binds to the U2snRNP. Both interactions lead to extensive conformational change and activation of the spliceosome.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td></tr> </table>

John S. de Banzie http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2582995&oldid=prev John S. de Banzie at 15:03, 18 March 2016 2016-03-18T15:03:02Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 15:03, 18 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The <scene='72/726441/Firstscene/2'>initial view<scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6).</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The <scene='72/726441/Firstscene/2'>initial view<<ins style="color: red; font-weight: bold; text-decoration: none;">/</ins>scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6).</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene='72/726441/Rnascene/1'>Focusing on the RNAs</scene> reveals extensive base pairing between the U4 and U6 snRNAs.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><scene='72/726441/Rnascene/1'>Focusing on the RNAs</scene> reveals extensive base pairing between the U4 and U6 snRNAs.</div></td></tr> </table>

John S. de Banzie http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2582994&oldid=prev John S. de Banzie at 15:02, 18 March 2016 2016-03-18T15:02:13Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 15:02, 18 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/2'></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>The <scene <del style="color: red; font-weight: bold; text-decoration: none;">name</del>='72/726441/Firstscene/2'>initial view<scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6).</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>The <scene='72/726441/Firstscene/2'>initial view<scene> shows proteins in white and the three snRNAs in colour (U4, U5, and U6).</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><scene <del style="color: red; font-weight: bold; text-decoration: none;">name</del>='72/726441/Rnascene/1'>Focusing on the RNAs</scene> reveals extensive base pairing between the U4 and U6 snRNAs.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><scene='72/726441/Rnascene/1'>Focusing on the RNAs</scene> reveals extensive base pairing between the U4 and U6 snRNAs.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The U2 snRNP binds to the region highlighted in blue in this view. The U1 snRNP binds to the U2snRNP. Both interactions lead to extensive conformational change and activation of the spliceosome.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The U2 snRNP binds to the region highlighted in blue in this view. The U1 snRNP binds to the U2snRNP. Both interactions lead to extensive conformational change and activation of the spliceosome.</div></td></tr> </table>

John S. de Banzie http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2582993&oldid=prev John S. de Banzie at 15:00, 18 March 2016 2016-03-18T15:00:22Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 15:00, 18 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/<del style="color: red; font-weight: bold; text-decoration: none;">1</del>'></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/<ins style="color: red; font-weight: bold; text-decoration: none;">2</ins>'></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Proteins are shown </del>in white, RNAs in <del style="color: red; font-weight: bold; text-decoration: none;">red</del>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">The <scene name='72/726441/Firstscene/2'>initial view<scene> shows proteins </ins>in white <ins style="color: red; font-weight: bold; text-decoration: none;">and the three snRNAs in colour (U4</ins>, <ins style="color: red; font-weight: bold; text-decoration: none;">U5, and U6).</ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><scene name='72/726441/Rnascene/1'>Focusing on the </ins>RNAs<ins style="color: red; font-weight: bold; text-decoration: none;"></scene> reveals extensive base pairing between the U4 and U6 snRNAs.</ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">The U2 snRNP binds to the region highlighted in blue </ins>in <ins style="color: red; font-weight: bold; text-decoration: none;">this view. The U1 snRNP binds to the U2snRNP. Both interactions lead to extensive conformational change and activation of the spliceosome</ins>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td></tr> </table>

John S. de Banzie http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2577946&oldid=prev John S. de Banzie at 21:44, 1 March 2016 2016-03-01T21:44:40Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 21:44, 1 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP'<del style="color: red; font-weight: bold; text-decoration: none;">> </del>[[5gan]]' scene='72/726441/Firstscene/1'></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' [[5gan]]' scene='72/726441/Firstscene/1'></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Proteins are shown in white, RNAs in red.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Proteins are shown in white, RNAs in red.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> </table>

John S. de Banzie http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2577945&oldid=prev John S. de Banzie at 21:39, 1 March 2016 2016-03-01T21:39:46Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 21:39, 1 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP'></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP'> <ins style="color: red; font-weight: bold; text-decoration: none;">[[5gan]]' </ins>scene=<ins style="color: red; font-weight: bold; text-decoration: none;">'</ins>72/726441/Firstscene/1<ins style="color: red; font-weight: bold; text-decoration: none;">'</ins>></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"><</del>scene <del style="color: red; font-weight: bold; text-decoration: none;">name</del>=<del style="color: red; font-weight: bold; text-decoration: none;">"</del>72/726441/Firstscene/1<del style="color: red; font-weight: bold; text-decoration: none;">"</del>><del style="color: red; font-weight: bold; text-decoration: none;">Holder</scene></del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Proteins are shown in white, RNAs in red.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Proteins are shown in white, RNAs in red.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> </table>

John S. de Banzie http://52.214.119.220/wiki/index.php?title=User:John_S._de_Banzie/Sandbox_4&diff=2577944&oldid=prev John S. de Banzie at 21:33, 1 March 2016 2016-03-01T21:33:35Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 21:33, 1 March 2016</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==Yeast U4/U6.U5 tri-snRNP==</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP' <scene name="72/726441/Firstscene/1">Holder</scene></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='5gan' size='640' side='right' caption='U4/U6.U5 snRNP'<ins style="color: red; font-weight: bold; text-decoration: none;">></ins></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Protein is </del>shown in white, <del style="color: red; font-weight: bold; text-decoration: none;">RNA </del>in red.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><scene name="72/726441/Firstscene/1">Holder</scene></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> </div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">Proteins are </ins>shown in white, <ins style="color: red; font-weight: bold; text-decoration: none;">RNAs </ins>in red.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>For the source article see Nguyen et al, 2016<ref>DOI 10.1038/nature16940</ref>.</div></td></tr> </table>

John S. de Banzie