User:Tom Gluick/glutamine synthetase/Assignment 8 - Revision history

Tom Gluick: /* Assessment */

2008-12-28T20:15:17Z

Assessment

←Older revision		Revision as of 20:15, 28 December 2008
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	The presentation had strong points and weak points. <br/>		The presentation had strong points and weak points. <br/>
-	One strong point is that the students produced a few fabulous visuals showing that students are capable of exercising their imagination while working with SAT.<br/>	+	One strong point is that the students produced a few fabulous visuals showing that students are capable of exercising their imagination while working with SAT. These students were effective at using background colors, colors, transparency and other commands to produce eye-catching visuals. Also, like other equally effective and better presentations, the material was organized well.<br/>
	One weak point is that these students had some difficulty with the WIKI script as the green links contain the default language. I do remember when meeting with other groups that other students had some intitial difficulty with the syntax of the script. I feel there is enough information available for students to write the script properly. Another weak point is that the visuals fail to effectively make the point presented in the the text; for instance see the last green link. The link that shows the Arg 172, the site of ribosylation fails to show where it is located in the subunit or the complex. This seemed to be a general failing on both mine and all students' part: I tried to emphasize that the various regions of GS to be discussed ought to be first presented in the GS complex, then the subunit and if necessary presented by itself. I must have failed in conveying this effectively.		One weak point is that these students had some difficulty with the WIKI script as the green links contain the default language. I do remember when meeting with other groups that other students had some intitial difficulty with the syntax of the script. I feel there is enough information available for students to write the script properly. Another weak point is that the visuals fail to effectively make the point presented in the the text; for instance see the last green link. The link that shows the Arg 172, the site of ribosylation fails to show where it is located in the subunit or the complex. This seemed to be a general failing on both mine and all students' part: I tried to emphasize that the various regions of GS to be discussed ought to be first presented in the GS complex, then the subunit and if necessary presented by itself. I must have failed in conveying this effectively.

Tom Gluick: /* Assessment */

2008-12-28T20:10:37Z

Assessment

←Older revision		Revision as of 20:10, 28 December 2008
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	==Assessment==		==Assessment==

-	These students had some difficulty with the WIKI script as the green links contain the default language. I do remember when meeting with other groups that other students had some intitial difficulty with the syntax of the script. I feel there is enough information available for students to write the script properly. <br/>
	The presentation had strong points and weak points. <br/>		The presentation had strong points and weak points. <br/>
	One strong point is that the students produced a few fabulous visuals showing that students are capable of exercising their imagination while working with SAT.<br/>		One strong point is that the students produced a few fabulous visuals showing that students are capable of exercising their imagination while working with SAT.<br/>
-	~~However, a~~ weak point is that the visuals fail to effectively make the point presented in the the text; for instance see the last green link. The link that shows the Arg 172, the site of ribosylation fails to show where it is located in the subunit or the complex. This seemed to be a general failing on both mine and all students' part: I tried to emphasize that the various regions of GS to be discussed ought to be first presented in the GS complex, then the subunit and if necessary presented by itself. I must have failed in conveying this effectively.	+	One weak point is that these students had some difficulty with the WIKI script as the green links contain the default language. I do remember when meeting with other groups that other students had some intitial difficulty with the syntax of the script. I feel there is enough information available for students to write the script properly. Another weak point is that the visuals fail to effectively make the point presented in the the text; for instance see the last green link. The link that shows the Arg 172, the site of ribosylation fails to show where it is located in the subunit or the complex. This seemed to be a general failing on both mine and all students' part: I tried to emphasize that the various regions of GS to be discussed ought to be first presented in the GS complex, then the subunit and if necessary presented by itself. I must have failed in conveying this effectively.

Tom Gluick: /* Assessment */

2008-12-28T20:08:17Z

Assessment

←Older revision		Revision as of 20:08, 28 December 2008
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	The presentation had strong points and weak points. <br/>		The presentation had strong points and weak points. <br/>
	One strong point is that the students produced a few fabulous visuals showing that students are capable of exercising their imagination while working with SAT.<br/>		One strong point is that the students produced a few fabulous visuals showing that students are capable of exercising their imagination while working with SAT.<br/>
-	However, a weak point is that the visuals fail to effectively make the point presented in the the text; for instance see the last green link. The link that shows the Arg ~~###~~, the site of ribosylation fails to show where it is located in the subunit or the complex. This seemed to be a general failing on both mine and all students' part: I tried to emphasize that the various regions of GS to be discussed ought to be first presented in the GS complex, then the subunit and if necessary presented by itself. I must have failed in conveying this effectively.	+	However, a weak point is that the visuals fail to effectively make the point presented in the the text; for instance see the last green link. The link that shows the Arg 172, the site of ribosylation fails to show where it is located in the subunit or the complex. This seemed to be a general failing on both mine and all students' part: I tried to emphasize that the various regions of GS to be discussed ought to be first presented in the GS complex, then the subunit and if necessary presented by itself. I must have failed in conveying this effectively.

Tom Gluick: /* Assessment */

2008-12-28T20:07:49Z

Assessment

←Older revision		Revision as of 20:07, 28 December 2008
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	These students had some difficulty with the WIKI script as the green links contain the default language. I do remember when meeting with other groups that other students had some intitial difficulty with the syntax of the script. I feel there is enough information available for students to write the script properly. <br/>		These students had some difficulty with the WIKI script as the green links contain the default language. I do remember when meeting with other groups that other students had some intitial difficulty with the syntax of the script. I feel there is enough information available for students to write the script properly. <br/>
	The presentation had strong points and weak points. <br/>		The presentation had strong points and weak points. <br/>
-	~~The presentation does show~~ that ~~some~~ fabulous visuals ~~can be made when~~ students ~~exercise~~ their imagination while working with SAT.<br/>	+	One strong point is that the students produced a few fabulous visuals showing that students are capable of exercising their imagination while working with SAT.<br/>
-	~~On the otherhand~~, ~~some~~ visuals fail to ~~emphasize~~ the text ~~effectively~~; for instance see the last green link.	+	However, a weak point is that the visuals fail to effectively make the point presented in the the text; for instance see the last green link. The link that shows the Arg ###, the site of ribosylation fails to show where it is located in the subunit or the complex. This seemed to be a general failing on both mine and all students' part: I tried to emphasize that the various regions of GS to be discussed ought to be first presented in the GS complex, then the subunit and if necessary presented by itself. I must have failed in conveying this effectively.

Tom Gluick: /* Assessment */

2008-12-28T19:55:39Z

Assessment

←Older revision		Revision as of 19:55, 28 December 2008
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	The presentation had strong points and weak points. <br/>		The presentation had strong points and weak points. <br/>
	The presentation does show that some fabulous visuals can be made when students exercise their imagination while working with SAT.<br/>		The presentation does show that some fabulous visuals can be made when students exercise their imagination while working with SAT.<br/>
-	On the otherhand, some of the ~~presentations ..~~.	+	On the otherhand, some visuals fail to emphasize the text effectively; for instance see the last green link.

Tom Gluick: /* Authors */

2008-12-28T19:15:42Z

Authors

←Older revision		Revision as of 19:15, 28 December 2008
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	Kary Atkinson<br/>		Kary Atkinson<br/>
	Murteza Shahkolahi<br/>		Murteza Shahkolahi<br/>
-	Annette Zeender	+	Annette Zeender<br/>
		+
		+	==Assessment==
		+
		+	These students had some difficulty with the WIKI script as the green links contain the default language. I do remember when meeting with other groups that other students had some intitial difficulty with the syntax of the script. I feel there is enough information available for students to write the script properly. <br/>
		+	The presentation had strong points and weak points. <br/>
		+	The presentation does show that some fabulous visuals can be made when students exercise their imagination while working with SAT.<br/>
		+	On the otherhand, some of the presentations ...

Tom Gluick: /* Assignment: My Intent */

2008-12-28T19:02:53Z

Assignment: My Intent

←Older revision		Revision as of 19:02, 28 December 2008
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	<span style="color:red">'''Assignment 8: IIIB: Central-loop:''' </span> Map the interactions involving the central loop that stabilize quaternary structure. Explain how these interactions contribute to quaternary structure stability.<ref name="review"/><ref name="struct"/><br/>		<span style="color:red">'''Assignment 8: IIIB: Central-loop:''' </span> Map the interactions involving the central loop that stabilize quaternary structure. Explain how these interactions contribute to quaternary structure stability.<ref name="review"/><ref name="struct"/><br/>

-	<span style="color:red">My hope and intent: </span> ~~This is a difficult assignment since the information on the loop is sparse and difficult to find.~~ I hoped the students would map the interactions the central loop makes with other components in Glutamine synthetase using the information in PDBsum as a guide. Comments upon how the the various interactions lead to stabilizing the complex would be left to their imaginations.	+	<span style="color:red">My hope and intent: </span> I hoped the students would map the interactions the central loop makes with other components in Glutamine synthetase using the information in PDBsum as a guide. Comments upon how the the various interactions lead to stabilizing the complex would be left to their imaginations.

	== Student Contribution ==		== Student Contribution ==

Tom Gluick: /* References: */

2008-12-28T19:00:28Z

References:

←Older revision		Revision as of 19:00, 28 December 2008
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	'''3.''' Yamashita, M. M., Almassy, R. J., Janson, C. A., Cascio, D., Eisenberg, D., Refined Atomic Model of Glutamine Synthetase at 3.5 A Resolution, The Journal of Biochemistry, 1989, Vol. 264, No. 30, 17681-17690		'''3.''' Yamashita, M. M., Almassy, R. J., Janson, C. A., Cascio, D., Eisenberg, D., Refined Atomic Model of Glutamine Synthetase at 3.5 A Resolution, The Journal of Biochemistry, 1989, Vol. 264, No. 30, 17681-17690
		+
		+	====Authors====
		+	Kary Atkinson<br/>
		+	Murteza Shahkolahi<br/>
		+	Annette Zeender

Tom Gluick: /* Student Contribution */

2008-12-28T18:56:59Z

Student Contribution

←Older revision		Revision as of 18:56, 28 December 2008
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	It is evident then that the central loop of glutamine synthetase (residues 156-188) is an important component of the enzyme, anchoring the subunits together and providing the spatial orientation necessary for activity. Therefore the central loop contributes both to the function and stabilization, via numerous hydrophobic interactions <scene name='User:Kary_Atkinson/Pro_glutamine_synthetase/11'>TextToBeDisplayed</scene> and four different hydrogen bonding interactions <scene name='User:Kary_Atkinson/Pro_glutamine_synthetase/10'>TextToBeDisplayed</scene> of the quartenary structure of Glutamine synthetase.		It is evident then that the central loop of glutamine synthetase (residues 156-188) is an important component of the enzyme, anchoring the subunits together and providing the spatial orientation necessary for activity. Therefore the central loop contributes both to the function and stabilization, via numerous hydrophobic interactions <scene name='User:Kary_Atkinson/Pro_glutamine_synthetase/11'>TextToBeDisplayed</scene> and four different hydrogen bonding interactions <scene name='User:Kary_Atkinson/Pro_glutamine_synthetase/10'>TextToBeDisplayed</scene> of the quartenary structure of Glutamine synthetase.

-	References:	+
		+	=== References:===

	'''1.''' Fisher, M. T., Stadtman, E. R., Oxidative Modification of Escherichia coli Glutamine Synthetase, The Journal of Biological Chemistry, 1992, Vol 267. No3, 1872-1880		'''1.''' Fisher, M. T., Stadtman, E. R., Oxidative Modification of Escherichia coli Glutamine Synthetase, The Journal of Biological Chemistry, 1992, Vol 267. No3, 1872-1880

Tom Gluick: /* References: */

2008-12-28T18:55:52Z

References:

←Older revision		Revision as of 18:55, 28 December 2008
Line 20:		Line 20:
	It is evident then that the central loop of glutamine synthetase (residues 156-188) is an important component of the enzyme, anchoring the subunits together and providing the spatial orientation necessary for activity. Therefore the central loop contributes both to the function and stabilization, via numerous hydrophobic interactions <scene name='User:Kary_Atkinson/Pro_glutamine_synthetase/11'>TextToBeDisplayed</scene> and four different hydrogen bonding interactions <scene name='User:Kary_Atkinson/Pro_glutamine_synthetase/10'>TextToBeDisplayed</scene> of the quartenary structure of Glutamine synthetase.		It is evident then that the central loop of glutamine synthetase (residues 156-188) is an important component of the enzyme, anchoring the subunits together and providing the spatial orientation necessary for activity. Therefore the central loop contributes both to the function and stabilization, via numerous hydrophobic interactions <scene name='User:Kary_Atkinson/Pro_glutamine_synthetase/11'>TextToBeDisplayed</scene> and four different hydrogen bonding interactions <scene name='User:Kary_Atkinson/Pro_glutamine_synthetase/10'>TextToBeDisplayed</scene> of the quartenary structure of Glutamine synthetase.

-	== References: ==	+	References:

	'''1.''' Fisher, M. T., Stadtman, E. R., Oxidative Modification of Escherichia coli Glutamine Synthetase, The Journal of Biological Chemistry, 1992, Vol 267. No3, 1872-1880		'''1.''' Fisher, M. T., Stadtman, E. R., Oxidative Modification of Escherichia coli Glutamine Synthetase, The Journal of Biological Chemistry, 1992, Vol 267. No3, 1872-1880