152d - Revision history

OCA at 06:25, 7 February 2024

OCA — Wed, 07 Feb 2024 06:25:12 GMT

←Older revision		Revision as of 06:25, 7 February 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=152D FirstGlance]. <br>		<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=152D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [https://pdbe.org/152d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [https://www.ebi.ac.uk/pdbsum/152d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=152d ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [https://pdbe.org/152d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [https://www.ebi.ac.uk/pdbsum/152d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=152d ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	In crystallographic structures of biological macromolecules, one can observe many hydration rings that originate at one water molecule, pass via hydrogen bonds through several others, and return to the original water molecule. Five-membered water rings have been thought to occur with greater frequency than other ring sizes. We describe a quantitative assessment of relationships between water ring size and frequency of occurrence in the vicinity of nucleic acid interfaces. This report focuses on low-temperature X-ray crystallographic structures of two anthracyclines, adriamycin (ADRI) and daunomycin (DAUN), bound to d(CGATCG) and on several DNA structures published previously by others. We have obtained excellent low-temperature (-160 degrees C, LT) X-ray intensity data for d(CGATCG)-adriamycin and d(CGATCG)-daunomycin with a multiwire area detector. The LTX-ray data sets contain 20% (daunomycin, LT-DAUN) and 35% (adriamycin, LT-ADRI) more reflections than were used to derive the original room-temperature (15 degrees C) structures [Frederick, C.A., Williams, L.D., Ughetto, G., van der Marel, G. A., van Boom, J.H., Rich, A., & Wang, A.H.-J. (1990) Biochemistry 29, 2538-2549]. The results show that five-membered water rings are not preferred over other ring sizes. This assessment is consistent with our observation of broad dispersion W-W-W angles (sigma = 20 degrees). In addition, we report that the thermal mobility, distinct from the static disorder, of the amino sugar of daunomycin and adriamycin is significantly greater than that of the rest of the complex. This mobility implies that if the central AT base pair is switched to a CG base pair, there should be a low energy cost in avoiding the guanine amino group. The energy difference (for the sugar-binding preference) between d(CGTACG) and d(CGCGCG) could be considerably less than 20 kcal/mol, a value proposed previously from computation.
-
-	Water ring structure at DNA interfaces: hydration and dynamics of DNA-anthracycline complexes.,Lipscomb LA, Peek ME, Zhou FX, Bertrand JA, VanDerveer D, Williams LD Biochemistry. 1994 Mar 29;33(12):3649-59. PMID:8142363<ref>PMID:8142363</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 152d" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:43, 24 November 2022

OCA — Thu, 24 Nov 2022 10:43:35 GMT

←Older revision		Revision as of 10:43, 24 November 2022
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bertrand~~, J A~~]]	+	[[Category: Bertrand JA]]
-	[[Category: Lipscomb~~, L A~~]]	+	[[Category: Lipscomb LA]]
-	[[Category: Peek~~, M E~~]]	+	[[Category: Peek ME]]
-	[[Category: VanDerveer, D]]	+	[[Category: VanDerveer D]]
-	[[Category: Williams~~, L D~~]]	+	[[Category: Williams LD]]
-	[[Category: Zhou~~, F X]]~~	+	[[Category: Zhou FX]]
-	~~[[Category: Complexed with drug]]~~	+
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Double helix]]~~	+
-	~~[[Category: Right handed dna~~]]	+

OCA at 10:13, 17 February 2021

OCA — Wed, 17 Feb 2021 10:13:53 GMT

←Older revision		Revision as of 10:13, 17 February 2021
Line 3:		Line 3:
	<StructureSection load='152d' size='340' side='right'caption='[[152d]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='152d' size='340' side='right'caption='[[152d]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=152D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=152D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [~~http~~://pdbe.org/152d PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/152d PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=152d ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [https://pdbe.org/152d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [https://www.ebi.ac.uk/pdbsum/152d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=152d ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:57, 10 May 2019

OCA — Fri, 10 May 2019 14:57:12 GMT

←Older revision		Revision as of 14:57, 10 May 2019
Line 1:		Line 1:

	==DIVERSITY OF WATER RING SIZE AT DNA INTERFACES: HYDRATION AND DYNAMICS OF DNA-ANTHRACYCLINE COMPLEXES==		==DIVERSITY OF WATER RING SIZE AT DNA INTERFACES: HYDRATION AND DYNAMICS OF DNA-ANTHRACYCLINE COMPLEXES==
-	<StructureSection load='152d' size='340' side='right' caption='[[152d]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='152d' size='340' side='right'caption='[[152d]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152D FirstGlance]. <br>		<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152D FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bertrand, J A]]		[[Category: Bertrand, J A]]
	[[Category: Lipscomb, L A]]		[[Category: Lipscomb, L A]]

OCA at 09:19, 9 August 2017

OCA — Wed, 09 Aug 2017 09:19:36 GMT

←Older revision		Revision as of 09:19, 9 August 2017
Line 1:		Line 1:
		+
	==DIVERSITY OF WATER RING SIZE AT DNA INTERFACES: HYDRATION AND DYNAMICS OF DNA-ANTHRACYCLINE COMPLEXES==		==DIVERSITY OF WATER RING SIZE AT DNA INTERFACES: HYDRATION AND DYNAMICS OF DNA-ANTHRACYCLINE COMPLEXES==
	<StructureSection load='152d' size='340' side='right' caption='[[152d]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='152d' size='340' side='right' caption='[[152d]], [[Resolution\|resolution]] 1.40Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152D FirstGlance]. <br>		<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152D FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [http://pdbe.org/152d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [http://www.ebi.ac.uk/pdbsum/152d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [http://pdbe.org/152d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [http://www.ebi.ac.uk/pdbsum/152d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=152d ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:56, 9 September 2015

OCA — Wed, 09 Sep 2015 15:56:26 GMT

←Older revision		Revision as of 15:56, 9 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152D FirstGlance]. <br>		<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152D FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [http://www.ebi.ac.uk/pdbsum/152d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [http://pdbe.org/152d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [http://www.ebi.ac.uk/pdbsum/152d PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 152d" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:11, 22 December 2014

OCA — Mon, 22 Dec 2014 11:11:00 GMT

←Older revision		Revision as of 11:11, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152D FirstGlance]. <br>		<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152D FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [http://www.ebi.ac.uk/pdbsum/152d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [http://www.ebi.ac.uk/pdbsum/152d PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bertrand, J A.]]	+	[[Category: Bertrand, J A]]
-	[[Category: Lipscomb, L A.]]	+	[[Category: Lipscomb, L A]]
-	[[Category: Peek, M E.]]	+	[[Category: Peek, M E]]
-	[[Category: VanDerveer, D.]]	+	[[Category: VanDerveer, D]]
-	[[Category: Williams, L D.]]	+	[[Category: Williams, L D]]
-	[[Category: Zhou, F X.]]	+	[[Category: Zhou, F X]]
	[[Category: Complexed with drug]]		[[Category: Complexed with drug]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Double helix]]		[[Category: Double helix]]
	[[Category: Right handed dna]]		[[Category: Right handed dna]]

OCA at 08:33, 23 July 2014

OCA — Wed, 23 Jul 2014 08:33:27 GMT

←Older revision		Revision as of 08:33, 23 July 2014
Line 1:		Line 1:
-	[[~~Image:~~152d.~~png~~\|~~left\|200px~~]]	+	==DIVERSITY OF WATER RING SIZE AT DNA INTERFACES: HYDRATION AND DYNAMICS OF DNA-ANTHRACYCLINE COMPLEXES==
		+	<StructureSection load='152d' size='340' side='right' caption='[[152d]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152D FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DM1:DAUNOMYCIN'>DM1</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=152d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=152d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=152d RCSB], [http://www.ebi.ac.uk/pdbsum/152d PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In crystallographic structures of biological macromolecules, one can observe many hydration rings that originate at one water molecule, pass via hydrogen bonds through several others, and return to the original water molecule. Five-membered water rings have been thought to occur with greater frequency than other ring sizes. We describe a quantitative assessment of relationships between water ring size and frequency of occurrence in the vicinity of nucleic acid interfaces. This report focuses on low-temperature X-ray crystallographic structures of two anthracyclines, adriamycin (ADRI) and daunomycin (DAUN), bound to d(CGATCG) and on several DNA structures published previously by others. We have obtained excellent low-temperature (-160 degrees C, LT) X-ray intensity data for d(CGATCG)-adriamycin and d(CGATCG)-daunomycin with a multiwire area detector. The LTX-ray data sets contain 20% (daunomycin, LT-DAUN) and 35% (adriamycin, LT-ADRI) more reflections than were used to derive the original room-temperature (15 degrees C) structures [Frederick, C.A., Williams, L.D., Ughetto, G., van der Marel, G. A., van Boom, J.H., Rich, A., & Wang, A.H.-J. (1990) Biochemistry 29, 2538-2549]. The results show that five-membered water rings are not preferred over other ring sizes. This assessment is consistent with our observation of broad dispersion W-W-W angles (sigma = 20 degrees). In addition, we report that the thermal mobility, distinct from the static disorder, of the amino sugar of daunomycin and adriamycin is significantly greater than that of the rest of the complex. This mobility implies that if the central AT base pair is switched to a CG base pair, there should be a low energy cost in avoiding the guanine amino group. The energy difference (for the sugar-binding preference) between d(CGTACG) and d(CGCGCG) could be considerably less than 20 kcal/mol, a value proposed previously from computation.

-	~~{{STRUCTURE_152d\| PDB=152d \| SCENE= }}~~	+	Water ring structure at DNA interfaces: hydration and dynamics of DNA-anthracycline complexes.,Lipscomb LA, Peek ME, Zhou FX, Bertrand JA, VanDerveer D, Williams LD Biochemistry. 1994 Mar 29;33(12):3649-59. PMID:8142363<ref>PMID:8142363</ref>

-	~~===DIVERSITY OF WATER RING SIZE AT DNA INTERFACES: HYDRATION AND DYNAMICS OF DNA-ANTHRACYCLINE COMPLEXES===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_8142363}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[152d]] is a 1 chain structure. Full crystallographic information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA].~~	+	</StructureSection>
	[[Category: Bertrand, J A.]]		[[Category: Bertrand, J A.]]
	[[Category: Lipscomb, L A.]]		[[Category: Lipscomb, L A.]]

OCA: Protected "152d" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 11:55:33 GMT

Protected "152d" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:55, 21 October 2012

OCA at 11:55, 21 October 2012

OCA — Sun, 21 Oct 2012 11:55:30 GMT

←Older revision		Revision as of 11:55, 21 October 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:152d.png\|left\|200px]]		[[Image:152d.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_152d", creates the "Structure Box" on the page.
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-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_152d\| PDB=152d \| SCENE= }}		{{STRUCTURE_152d\| PDB=152d \| SCENE= }}

	===DIVERSITY OF WATER RING SIZE AT DNA INTERFACES: HYDRATION AND DYNAMICS OF DNA-ANTHRACYCLINE COMPLEXES===		===DIVERSITY OF WATER RING SIZE AT DNA INTERFACES: HYDRATION AND DYNAMICS OF DNA-ANTHRACYCLINE COMPLEXES===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_8142363}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 8142363 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_8142363}}		{{ABSTRACT_PUBMED_8142363}}

	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA].	+	[[152d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=152D OCA].
-		+
-	~~==Reference==~~	+
-	Water ring structure at DNA interfaces: hydration and dynamics of DNA-anthracycline complexes., Lipscomb LA, Peek ME, Zhou FX, Bertrand JA, VanDerveer D, Williams LD, Biochemistry. 1994 Mar 29;33(12):3649-59. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8142363 8142363]	+
	[[Category: Bertrand, J A.]]		[[Category: Bertrand, J A.]]
	[[Category: Lipscomb, L A.]]		[[Category: Lipscomb, L A.]]
Line 31:		Line 16:
	[[Category: Zhou, F X.]]		[[Category: Zhou, F X.]]
	[[Category: Complexed with drug]]		[[Category: Complexed with drug]]
		+	[[Category: Dna]]
	[[Category: Double helix]]		[[Category: Double helix]]
	[[Category: Right handed dna]]		[[Category: Right handed dna]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 15:31:30 2008''