184d - Revision history

OCA at 06:26, 7 February 2024

OCA — Wed, 07 Feb 2024 06:26:03 GMT

←Older revision		Revision as of 06:26, 7 February 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=184D FirstGlance]. <br>		<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=184D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [https://pdbe.org/184d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [https://www.ebi.ac.uk/pdbsum/184d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=184d ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [https://pdbe.org/184d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [https://www.ebi.ac.uk/pdbsum/184d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=184d ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	BACKGROUND: The flexibility of DNA enables it to adopt three interconvertible types of duplex termed the A-, B- and Z-forms. It can also produce hairpin loops, triplex structures and guanine-rich quadruplex structures. Conformational flexibility assists in the tight packaging of DNA, for example in chromosomes. This is important given the large quantity of genetic information that must be packaged efficiently. Moreover, the ability of DNA to specifically self-associate or interact with complementary sequences is fundamental to many biological processes. Structural studies provide information about DNA conformation and DNA-DNA interactions and suggest features that might be relevant to how the molecule performs its biological role. RESULTS: We have characterized the structure of a synthetic heptanucleotide that folds into a novel loop structure. The loop is stabilized by association with a cation, by intra-strand hydrogen bonds between guanine and cytosine that are distinct from the normal Watson-Crick hydrogen bonds, and by van der Waals interactions. Two loops associate through the formation of four G.C pairs that exhibit pronounced base-stacking interactions. The formation of a symmetric A.A base pair further stabilizes loop dimerization. Stacking of the A.A pair on a symmetry-related A.A pairing assists the formation of a four-stranded assembly. A T.T pairing is also observed between symmetry-related loops. CONCLUSIONS: This analysis provides a rare example of an experimentally determined non-duplex DNA structure. It provides conformational detail relevant to the tight packaging or folding of a DNA strand and illustrates how a cation might modulate phosphate-phosphate repulsion in a tightly packed structure. The observation of base quartets involving G.C base pairs suggests a further structure to be considered in DNA-DNA interactions. The structure also provides detailed geometries for A.A and T.T base pairs.
-
-	Self-association of a DNA loop creates a quadruplex: crystal structure of d(GCATGCT) at 1.8 A resolution.,Leonard GA, Zhang S, Peterson MR, Harrop SJ, Helliwell JR, Cruse WB, d'Estaintot BL, Kennard O, Brown T, Hunter WN Structure. 1995 Apr 15;3(4):335-40. PMID:7613864<ref>PMID:7613864</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 184d" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:44, 24 November 2022

OCA — Thu, 24 Nov 2022 10:44:46 GMT

←Older revision		Revision as of 10:44, 24 November 2022
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Brown, T]]	+	[[Category: Brown T]]
-	[[Category: Cruse~~, W B.T]]~~	+	[[Category: Cruse WBT]]
-	~~[[Category: Estaintot, B Langlois D~~]]	+	[[Category: Harrop SJ]]
-	[[Category: Harrop~~, S J~~]]	+	[[Category: Helliwell JR]]
-	[[Category: Helliwell~~, J R~~]]	+	[[Category: Hunter WN]]
-	[[Category: Hunter~~, W N~~]]	+	[[Category: Kennard O]]
-	[[Category: Kennard, O]]	+	[[Category: Langlois D'Estaintot B]]
-	[[Category: ~~Leonard, G A~~]]	+	[[Category: Leonard GA]]
-	[[Category: ~~Peterson, M R~~]]	+	[[Category: Peterson MR]]
-	[[Category: ~~Zhang, S~~]]	+	[[Category: Zhang S]]
-	[[Category: ~~Dna]]~~	+
-	~~[[Category: Loop]]~~	+
-	~~[[Category: Quadruple helix]]~~	+
-	~~[[Category: Tetraplex]]~~	+
-	~~[[Category: U-dna~~]]	+

OCA at 10:14, 17 February 2021

OCA — Wed, 17 Feb 2021 10:14:33 GMT

←Older revision		Revision as of 10:14, 17 February 2021
Line 3:		Line 3:
	<StructureSection load='184d' size='340' side='right'caption='[[184d]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='184d' size='340' side='right'caption='[[184d]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=184D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=184D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [~~http~~://pdbe.org/184d PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/184d PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=184d ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [https://pdbe.org/184d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [https://www.ebi.ac.uk/pdbsum/184d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=184d ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:01, 10 May 2019

OCA — Fri, 10 May 2019 14:01:46 GMT

←Older revision		Revision as of 14:01, 10 May 2019
Line 1:		Line 1:

	==SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION==		==SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION==
-	<StructureSection load='184d' size='340' side='right' caption='[[184d]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='184d' size='340' side='right'caption='[[184d]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184D FirstGlance]. <br>		<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184D FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Brown, T]]		[[Category: Brown, T]]
	[[Category: Cruse, W B.T]]		[[Category: Cruse, W B.T]]

OCA at 09:11, 9 August 2017

OCA — Wed, 09 Aug 2017 09:11:52 GMT

←Older revision		Revision as of 09:11, 9 August 2017
Line 1:		Line 1:
		+
	==SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION==		==SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION==
	<StructureSection load='184d' size='340' side='right' caption='[[184d]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='184d' size='340' side='right' caption='[[184d]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184D FirstGlance]. <br>		<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184D FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [http://pdbe.org/184d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [http://www.ebi.ac.uk/pdbsum/184d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [http://pdbe.org/184d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [http://www.ebi.ac.uk/pdbsum/184d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=184d ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:44, 9 September 2015

OCA — Wed, 09 Sep 2015 15:44:57 GMT

←Older revision		Revision as of 15:44, 9 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184D FirstGlance]. <br>		<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184D FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [http://www.ebi.ac.uk/pdbsum/184d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [http://pdbe.org/184d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [http://www.ebi.ac.uk/pdbsum/184d PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 184d" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:53, 22 December 2014

OCA — Mon, 22 Dec 2014 04:53:05 GMT

←Older revision		Revision as of 04:53, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184D FirstGlance]. <br>		<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184D FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [http://www.ebi.ac.uk/pdbsum/184d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [http://www.ebi.ac.uk/pdbsum/184d PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Brown, T.]]	+	[[Category: Brown, T]]
-	[[Category: Cruse, W B.T.]]	+	[[Category: Cruse, W B.T]]
-	[[Category: Estaintot, B Langlois D.]]	+	[[Category: Estaintot, B Langlois D]]
-	[[Category: Harrop, S J.]]	+	[[Category: Harrop, S J]]
-	[[Category: Helliwell, J R.]]	+	[[Category: Helliwell, J R]]
-	[[Category: Hunter, W N.]]	+	[[Category: Hunter, W N]]
-	[[Category: Kennard, O.]]	+	[[Category: Kennard, O]]
-	[[Category: Leonard, G A.]]	+	[[Category: Leonard, G A]]
-	[[Category: Peterson, M R.]]	+	[[Category: Peterson, M R]]
-	[[Category: Zhang, S.]]	+	[[Category: Zhang, S]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Loop]]		[[Category: Loop]]

OCA at 05:33, 8 June 2014

OCA — Sun, 08 Jun 2014 05:33:35 GMT

←Older revision		Revision as of 05:33, 8 June 2014
Line 1:		Line 1:
-	[[~~Image:~~184d.~~png~~\|~~left\|200px~~]]	+	==SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION==
		+	<StructureSection load='184d' size='340' side='right' caption='[[184d]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184D FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=184d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=184d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=184d RCSB], [http://www.ebi.ac.uk/pdbsum/184d PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	BACKGROUND: The flexibility of DNA enables it to adopt three interconvertible types of duplex termed the A-, B- and Z-forms. It can also produce hairpin loops, triplex structures and guanine-rich quadruplex structures. Conformational flexibility assists in the tight packaging of DNA, for example in chromosomes. This is important given the large quantity of genetic information that must be packaged efficiently. Moreover, the ability of DNA to specifically self-associate or interact with complementary sequences is fundamental to many biological processes. Structural studies provide information about DNA conformation and DNA-DNA interactions and suggest features that might be relevant to how the molecule performs its biological role. RESULTS: We have characterized the structure of a synthetic heptanucleotide that folds into a novel loop structure. The loop is stabilized by association with a cation, by intra-strand hydrogen bonds between guanine and cytosine that are distinct from the normal Watson-Crick hydrogen bonds, and by van der Waals interactions. Two loops associate through the formation of four G.C pairs that exhibit pronounced base-stacking interactions. The formation of a symmetric A.A base pair further stabilizes loop dimerization. Stacking of the A.A pair on a symmetry-related A.A pairing assists the formation of a four-stranded assembly. A T.T pairing is also observed between symmetry-related loops. CONCLUSIONS: This analysis provides a rare example of an experimentally determined non-duplex DNA structure. It provides conformational detail relevant to the tight packaging or folding of a DNA strand and illustrates how a cation might modulate phosphate-phosphate repulsion in a tightly packed structure. The observation of base quartets involving G.C base pairs suggests a further structure to be considered in DNA-DNA interactions. The structure also provides detailed geometries for A.A and T.T base pairs.

-	~~{{STRUCTURE_184d\| PDB=184d \| SCENE= }}~~	+	Self-association of a DNA loop creates a quadruplex: crystal structure of d(GCATGCT) at 1.8 A resolution.,Leonard GA, Zhang S, Peterson MR, Harrop SJ, Helliwell JR, Cruse WB, d'Estaintot BL, Kennard O, Brown T, Hunter WN Structure. 1995 Apr 15;3(4):335-40. PMID:7613864<ref>PMID:7613864</ref>

-	~~===SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_7613864}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[184d]] is~~ a ~~1 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=184D OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:007613864<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Brown, T.]]		[[Category: Brown, T.]]
	[[Category: Cruse, W B.T.]]		[[Category: Cruse, W B.T.]]

OCA: Protected "184d" [edit=sysop:move=sysop]

OCA — Tue, 14 Aug 2012 14:46:34 GMT

Protected "184d" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:46, 14 August 2012

OCA at 14:46, 14 August 2012

OCA — Tue, 14 Aug 2012 14:46:32 GMT

←Older revision		Revision as of 14:46, 14 August 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:184d.png\|left\|200px]]		[[Image:184d.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_184d", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_184d\| PDB=184d \| SCENE= }}		{{STRUCTURE_184d\| PDB=184d \| SCENE= }}

	===SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION===		===SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_7613864}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 7613864 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_7613864}}		{{ABSTRACT_PUBMED_7613864}}

	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA].	+	[[184d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=184D OCA].

	==Reference==		==Reference==
-	Self-association of a DNA loop creates a quadruplex: crystal structure of d(GCATGCT) at 1.8 A resolution., Leonard GA, Zhang S, Peterson MR, Harrop SJ, Helliwell JR, Cruse WB, d'Estaintot BL, Kennard O, Brown T, Hunter WN, Structure. 1995 Apr 15;3(4):335-40. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~7613864 7613864]~~	+	<ref group="xtra">PMID:007613864</ref><references group="xtra"/>
	[[Category: Brown, T.]]		[[Category: Brown, T.]]
	[[Category: Cruse, W B.T.]]		[[Category: Cruse, W B.T.]]
Line 34:		Line 22:
	[[Category: Peterson, M R.]]		[[Category: Peterson, M R.]]
	[[Category: Zhang, S.]]		[[Category: Zhang, S.]]
		+	[[Category: Dna]]
	[[Category: Loop]]		[[Category: Loop]]
	[[Category: Quadruple helix]]		[[Category: Quadruple helix]]
	[[Category: Tetraplex]]		[[Category: Tetraplex]]
	[[Category: U-dna]]		[[Category: U-dna]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 15:38:02 2008''