1914 - Revision history

OCA at 10:44, 24 November 2022

OCA — Thu, 24 Nov 2022 10:44:59 GMT

←Older revision		Revision as of 10:44, 24 November 2022
Line 3:		Line 3:
	<StructureSection load='1914' size='340' side='right'caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>		<StructureSection load='1914' size='340' side='right'caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1914 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1914 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [https://pdbe.org/1914 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [https://www.ebi.ac.uk/pdbsum/1914 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1914 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [https://pdbe.org/1914 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [https://www.ebi.ac.uk/pdbsum/1914 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1914 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/SRP14_MOUSE SRP14_MOUSE]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.	+	[https://www.uniprot.org/uniprot/SRP14_MOUSE SRP14_MOUSE] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aberg, A]]	+	[[Category: Mus musculus]]
-	[[Category: Birse, D]]	+	[[Category: Aberg A]]
-	[[Category: Cusack, S]]	+	[[Category: Birse D]]
-	[[Category: Kapp, U]]	+	[[Category: Cusack S]]
-	[[Category: Strub, K]]	+	[[Category: Kapp U]]
-	~~[[Category: Alu domain]]~~	+	[[Category: Strub K]]
-	~~[[Category: Rna binding]]~~	+
-	~~[[Category: Translation regulation~~]]	+

OCA at 10:14, 17 February 2021

OCA — Wed, 17 Feb 2021 10:14:41 GMT

←Older revision		Revision as of 10:14, 17 February 2021
Line 3:		Line 3:
	<StructureSection load='1914' size='340' side='right'caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>		<StructureSection load='1914' size='340' side='right'caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1914 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1914 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [~~http~~://pdbe.org/1914 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1914 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1914 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [https://pdbe.org/1914 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [https://www.ebi.ac.uk/pdbsum/1914 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1914 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SRP14_MOUSE SRP14_MOUSE]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.	+	[[https://www.uniprot.org/uniprot/SRP14_MOUSE SRP14_MOUSE]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:00, 10 May 2019

OCA — Fri, 10 May 2019 15:00:53 GMT

←Older revision		Revision as of 15:00, 10 May 2019
Line 1:		Line 1:

	==SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14==		==SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14==
-	<StructureSection load='1914' size='340' side='right' caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>	+	<StructureSection load='1914' size='340' side='right'caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1914]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance]. <br>
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Aberg, A]]		[[Category: Aberg, A]]
	[[Category: Birse, D]]		[[Category: Birse, D]]

OCA at 09:21, 9 August 2017

OCA — Wed, 09 Aug 2017 09:21:24 GMT

←Older revision		Revision as of 09:21, 9 August 2017
Line 1:		Line 1:
		+
	==SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14==		==SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14==
	<StructureSection load='1914' size='340' side='right' caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>		<StructureSection load='1914' size='340' side='right' caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [http://pdbe.org/1914 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [http://www.ebi.ac.uk/pdbsum/1914 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [http://pdbe.org/1914 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [http://www.ebi.ac.uk/pdbsum/1914 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1914 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 24:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Lk3 transgenic mice]]
	[[Category: Aberg, A]]		[[Category: Aberg, A]]
	[[Category: Birse, D]]		[[Category: Birse, D]]

OCA at 15:59, 9 September 2015

OCA — Wed, 09 Sep 2015 15:59:30 GMT

←Older revision		Revision as of 15:59, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='1914' size='340' side='right' caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>		<StructureSection load='1914' size='340' side='right' caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [http://www.ebi.ac.uk/pdbsum/1914 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [http://pdbe.org/1914 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [http://www.ebi.ac.uk/pdbsum/1914 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1914" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Aberg, A]]		[[Category: Aberg, A]]
	[[Category: Birse, D]]		[[Category: Birse, D]]

OCA at 23:46, 24 December 2014

OCA — Wed, 24 Dec 2014 23:46:27 GMT

←Older revision		Revision as of 23:46, 24 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [http://www.ebi.ac.uk/pdbsum/1914 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [http://www.ebi.ac.uk/pdbsum/1914 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SRP14_MOUSE SRP14_MOUSE]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 11:13, 22 December 2014

OCA — Mon, 22 Dec 2014 11:13:38 GMT

←Older revision		Revision as of 11:13, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1914]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [http://www.ebi.ac.uk/pdbsum/1914 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [http://www.ebi.ac.uk/pdbsum/1914 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Aberg, A.]]	+	[[Category: Aberg, A]]
-	[[Category: Birse, D.]]	+	[[Category: Birse, D]]
-	[[Category: Cusack, S.]]	+	[[Category: Cusack, S]]
-	[[Category: Kapp, U.]]	+	[[Category: Kapp, U]]
-	[[Category: Strub, K.]]	+	[[Category: Strub, K]]
	[[Category: Alu domain]]		[[Category: Alu domain]]
	[[Category: Rna binding]]		[[Category: Rna binding]]
	[[Category: Translation regulation]]		[[Category: Translation regulation]]

OCA at 08:35, 23 July 2014

OCA — Wed, 23 Jul 2014 08:35:03 GMT

←Older revision		Revision as of 08:35, 23 July 2014
Line 1:		Line 1:
-	[[~~Image~~:1914.~~png~~\|~~left\|200px~~]]	+	==SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14==
		+	<StructureSection load='1914' size='340' side='right' caption='[[1914]], [[Resolution\|resolution]] 2.53Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1914]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1914 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1914 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1914 RCSB], [http://www.ebi.ac.uk/pdbsum/1914 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The mammalian signal recognition particle (SRP) is an 11S cytoplasmic ribonucleoprotein that plays an essential role in protein sorting. SRP recognizes the signal sequence of the nascent polypeptide chain emerging from the ribosome, and targets the ribosome-nascent chain-SRP complex to the rough endoplasmic reticulum. The SRP consists of six polypeptides (SRP9, SRP14, SRP19, SRP54, SRP68 and SRP72) and a single 300 nucleotide RNA molecule. SRP9 and SRP14 proteins form a heterodimer that binds to the Alu domain of SRP RNA which is responsible for translation arrest. We report the first crystal structure of a mammalian SRP protein, that of the mouse SRP9/14 heterodimer, determined at 2.5 A resolution. SRP9 and SRP14 are found to be structurally homologous, containing the same alpha-beta-beta-beta-alpha fold. This we designate the Alu binding module (Alu bm), an additional member of the family of small alpha/beta RNA binding domains. The heterodimer has pseudo 2-fold symmetry and is saddle like, comprising a strongly curved six-stranded amphipathic beta-sheet with the four helices packed on the convex side and the exposed concave surface being lined with positively charged residues.

-	~~{{STRUCTURE_1914\| PDB=1914 \| SCENE= }}~~	+	The crystal structure of the signal recognition particle Alu RNA binding heterodimer, SRP9/14.,Birse DE, Kapp U, Strub K, Cusack S, Aberg A EMBO J. 1997 Jul 1;16(13):3757-66. PMID:9233785<ref>PMID:9233785</ref>

-	~~===SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER~~, ~~SRP9/14===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9233785}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1914]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA].~~	+

	==See Also==		==See Also==
	*[[Signal recognition particle protein\|Signal recognition particle protein]]		*[[Signal recognition particle protein\|Signal recognition particle protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:009233785<~~/~~ref~~><~~ref group="xtra">PMID:015215468</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Aberg, A.]]		[[Category: Aberg, A.]]

OCA at 10:21, 20 October 2012

OCA — Sat, 20 Oct 2012 10:21:43 GMT

←Older revision		Revision as of 10:21, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1914]] is a 1 chain structure ~~of [[Signal recognition particle protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA].	+	[[1914]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA].

	==See Also==		==See Also==

OCA at 01:51, 26 July 2012

OCA — Thu, 26 Jul 2012 01:51:05 GMT

←Older revision		Revision as of 01:51, 26 July 2012
Line 1:		Line 1:
	[[Image:1914.png\|left\|200px]]		[[Image:1914.png\|left\|200px]]

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	{{STRUCTURE_1914\| PDB=1914 \| SCENE= }}		{{STRUCTURE_1914\| PDB=1914 \| SCENE= }}

	===SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14===		===SIGNAL RECOGNITION PARTICLE ALU RNA BINDING HETERODIMER, SRP9/14===

-
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	{{ABSTRACT_PUBMED_9233785}}		{{ABSTRACT_PUBMED_9233785}}

	==About this Structure==		==About this Structure==
-	[[1914]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA].	+	[[1914]] is a 1 chain structure of [[Signal recognition particle protein]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1914 OCA].

	==See Also==		==See Also==
-	*[[~~Nobel Prizes for 3D Molecular Structure]]~~	+	*[[Signal recognition particle protein\|Signal recognition particle protein]]
-	*[[Treatments:Dipeptidyl Peptidase-4 Inhibitor Pharmacokinetics]]	+
-	*[[User:Wayne Decatur/Interactions between Antibiotics and the Ribosome]]	+

	==Reference==		==Reference==