1a13 - Revision history

OCA at 11:31, 22 November 2023

OCA — Wed, 22 Nov 2023 11:31:56 GMT

←Older revision		Revision as of 11:31, 22 November 2023
Line 1:		Line 1:

	==G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X, NMR, 14 STRUCTURES==		==G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X, NMR, 14 STRUCTURES==
-	<StructureSection load='1a13' size='340' side='right'caption='[[1a13~~]], [[NMR_Ensembles_of_Models \| 14 NMR models~~]]' scene=''>	+	<StructureSection load='1a13' size='340' side='right'caption='[[1a13]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Japanese_hornet Japanese hornet~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A13 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vespa_simillima_xanthoptera Vespa simillima xanthoptera]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A13 FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [https://pdbe.org/1a13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [https://www.ebi.ac.uk/pdbsum/1a13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a13 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [https://pdbe.org/1a13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [https://www.ebi.ac.uk/pdbsum/1a13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a13 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MAST_VESXA MAST_VESXA]] Mast cell degranulating peptide. Activates G proteins that couple to phospholipase C.	+	[https://www.uniprot.org/uniprot/MAST_VESXA MAST_VESXA] Mast cell degranulating peptide. Activates G proteins that couple to phospholipase C.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Japanese hornet]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kohno, T]]	+	[[Category: Vespa simillima xanthoptera]]
-	[[Category: Kusunoki, H]]	+	[[Category: Kohno T]]
-	[[Category: Miyazawa, T]]	+	[[Category: Kusunoki H]]
-	[[Category: Sato, K]]	+	[[Category: Miyazawa T]]
-	[[Category: Wakamatsu, K]]	+	[[Category: Sato K]]
-	~~[[Category: Mast cell degranulation~~]]	+	[[Category: Wakamatsu K]]

OCA at 10:20, 16 February 2022

OCA — Wed, 16 Feb 2022 10:20:35 GMT

←Older revision		Revision as of 10:20, 16 February 2022
Line 3:		Line 3:
	<StructureSection load='1a13' size='340' side='right'caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>		<StructureSection load='1a13' size='340' side='right'caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A13 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Japanese_hornet Japanese hornet]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A13 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [https://pdbe.org/1a13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [https://www.ebi.ac.uk/pdbsum/1a13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a13 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [https://pdbe.org/1a13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [https://www.ebi.ac.uk/pdbsum/1a13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a13 ProSAT]</span></td></tr>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Japanese hornet]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Kohno, T]]		[[Category: Kohno, T]]

OCA at 10:15, 17 February 2021

OCA — Wed, 17 Feb 2021 10:15:18 GMT

←Older revision		Revision as of 10:15, 17 February 2021
Line 3:		Line 3:
	<StructureSection load='1a13' size='340' side='right'caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>		<StructureSection load='1a13' size='340' side='right'caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1A13 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A13 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [~~http~~://pdbe.org/1a13 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1a13 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1a13 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [https://pdbe.org/1a13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [https://www.ebi.ac.uk/pdbsum/1a13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a13 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MAST_VESXA MAST_VESXA]] Mast cell degranulating peptide. Activates G proteins that couple to phospholipase C.	+	[[https://www.uniprot.org/uniprot/MAST_VESXA MAST_VESXA]] Mast cell degranulating peptide. Activates G proteins that couple to phospholipase C.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:00, 10 May 2019

OCA — Fri, 10 May 2019 15:00:51 GMT

←Older revision		Revision as of 15:00, 10 May 2019
Line 1:		Line 1:

	==G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X, NMR, 14 STRUCTURES==		==G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X, NMR, 14 STRUCTURES==
-	<StructureSection load='1a13' size='340' side='right' caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>	+	<StructureSection load='1a13' size='340' side='right'caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A13 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A13 FirstGlance]. <br>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Kohno, T]]		[[Category: Kohno, T]]
	[[Category: Kusunoki, H]]		[[Category: Kusunoki, H]]

OCA at 09:21, 9 August 2017

OCA — Wed, 09 Aug 2017 09:21:24 GMT

←Older revision		Revision as of 09:21, 9 August 2017
Line 1:		Line 1:
		+
	==G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X, NMR, 14 STRUCTURES==		==G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X, NMR, 14 STRUCTURES==
	<StructureSection load='1a13' size='340' side='right' caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>		<StructureSection load='1a13' size='340' side='right' caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Japanese_hornet Japanese hornet]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A13 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A13 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [http://pdbe.org/1a13 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [http://www.ebi.ac.uk/pdbsum/1a13 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [http://pdbe.org/1a13 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [http://www.ebi.ac.uk/pdbsum/1a13 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a13 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Japanese hornet]]
	[[Category: Kohno, T]]		[[Category: Kohno, T]]
	[[Category: Kusunoki, H]]		[[Category: Kusunoki, H]]

OCA at 15:59, 9 September 2015

OCA — Wed, 09 Sep 2015 15:59:34 GMT

←Older revision		Revision as of 15:59, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='1a13' size='340' side='right' caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>		<StructureSection load='1a13' size='340' side='right' caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Vespa_simillima_xanthoptera Vespa simillima xanthoptera~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A13 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_hornet Japanese hornet]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A13 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [http://www.ebi.ac.uk/pdbsum/1a13 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [http://pdbe.org/1a13 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [http://www.ebi.ac.uk/pdbsum/1a13 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1a13" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Vespa simillima xanthoptera~~]]	+	[[Category: Japanese hornet]]
	[[Category: Kohno, T]]		[[Category: Kohno, T]]
	[[Category: Kusunoki, H]]		[[Category: Kusunoki, H]]

OCA at 03:05, 25 December 2014

OCA — Thu, 25 Dec 2014 03:05:53 GMT

←Older revision		Revision as of 03:05, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [http://www.ebi.ac.uk/pdbsum/1a13 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [http://www.ebi.ac.uk/pdbsum/1a13 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MAST_VESXA MAST_VESXA]] Mast cell degranulating peptide. Activates G proteins that couple to phospholipase C.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 09:15, 22 December 2014

OCA — Mon, 22 Dec 2014 09:15:04 GMT

←Older revision		Revision as of 09:15, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vespa_simillima_xanthoptera Vespa simillima xanthoptera]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A13 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vespa_simillima_xanthoptera Vespa simillima xanthoptera]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A13 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [http://www.ebi.ac.uk/pdbsum/1a13 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [http://www.ebi.ac.uk/pdbsum/1a13 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Vespa simillima xanthoptera]]		[[Category: Vespa simillima xanthoptera]]
-	[[Category: Kohno, T.]]	+	[[Category: Kohno, T]]
-	[[Category: Kusunoki, H.]]	+	[[Category: Kusunoki, H]]
-	[[Category: Miyazawa, T.]]	+	[[Category: Miyazawa, T]]
-	[[Category: Sato, K.]]	+	[[Category: Sato, K]]
-	[[Category: Wakamatsu, K.]]	+	[[Category: Wakamatsu, K]]
	[[Category: Mast cell degranulation]]		[[Category: Mast cell degranulation]]

OCA at 05:48, 8 June 2014

OCA — Sun, 08 Jun 2014 05:48:17 GMT

←Older revision		Revision as of 05:48, 8 June 2014
Line 1:		Line 1:
-	[[~~Image:~~1a13.~~png~~\|~~left\|200px~~]]	+	==G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X, NMR, 14 STRUCTURES==
		+	<StructureSection load='1a13' size='340' side='right' caption='[[1a13]], [[NMR_Ensembles_of_Models \| 14 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1a13]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vespa_simillima_xanthoptera Vespa simillima xanthoptera]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A13 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a13 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a13 RCSB], [http://www.ebi.ac.uk/pdbsum/1a13 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Mastoparans, a family of tetradecapeptides from wasp venom, have been used as convenient low molecular weight models of receptors coupled to GTP-binding regulatory proteins (G proteins) for the understanding of the interaction between G proteins and receptors. Sukumar and Higashijima have analyzed the conformation of mastoparan-X (MP-X) bound to the G protein alpha-subunit using proton two-dimensional transferred nuclear Overhauser effect (TRNOE) spectroscopy [Sukumar, M., and Higashijima, T. (1992) J. Biol. Chem., 267, 21421-21424]. The resultant structure, however, was not well-defined due to severe overlap of peptide proton resonances. To determine the G protein-bound conformation of MP-X in detail, we have analyzed this interaction by heteronuclear multidimensional TRNOE experiments of MP-X uniformly enriched with 15N and/or 13C. By solving the overlap problem, we were able to determine the precise conformation of MP-X bound to Gi1alpha: the peptide adopts an amphiphilic alpha-helix from Trp3 to C-terminal Leu14, and the atomic root-mean-square deviation (rmsd) values in this portion about the averaged coordinates were 0.27 +/- 0.07 A for the backbone atoms (N, Calpha, C') and 0.84 +/- 0.16 A for all heavy atoms. These values are much smaller than the corresponding rmsd values of the structures obtained from the proton 2D TRNOE spectrum alone: 1.70 +/- 0.41 A for the backbone atoms (N, Calpha, C') and 2.84 +/- 0.51 A for all heavy atoms. Our results indicate that the heteronuclear multidimensional TRNOE experiments of peptides uniformly enriched with stable isotopes are a very powerful tool for analyzing the conformation of short peptides bound to large proteins. We will also discuss the structure-activity relationships of mastoparans in activating G proteins on the basis of the precise structure of MP-X bound to Gi1alpha.

-	~~{{STRUCTURE_1a13\| PDB=1a13 \| SCENE= }}~~	+	G protein-bound conformation of mastoparan-X: heteronuclear multidimensional transferred nuclear overhauser effect analysis of peptide uniformly enriched with 13C and 15N.,Kusunoki H, Wakamatsu K, Sato K, Miyazawa T, Kohno T Biochemistry. 1998 Apr 7;37(14):4782-90. PMID:9537994<ref>PMID:9537994</ref>

-	~~===G PROTEIN-BOUND CONFORMATION OF MASTOPARAN-X~~, ~~NMR, 14 STRUCTURES===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9537994}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1a13]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Vespa_simillima_xanthoptera Vespa simillima xanthoptera]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1A13 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:009537994<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Vespa simillima xanthoptera]]		[[Category: Vespa simillima xanthoptera]]
	[[Category: Kohno, T.]]		[[Category: Kohno, T.]]

OCA: Protected "1a13" [edit=sysop:move=sysop]

OCA — Tue, 14 Aug 2012 16:37:54 GMT

Protected "1a13" [edit=sysop:move=sysop]

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Revision as of 16:37, 14 August 2012