1a4c - Revision history

OCA at 10:46, 2 August 2023

OCA — Wed, 02 Aug 2023 10:46:24 GMT

←Older revision		Revision as of 10:46, 2 August 2023
Line 3:		Line 3:
	<StructureSection load='1a4c' size='340' side='right'caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>		<StructureSection load='1a4c' size='340' side='right'caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"alcaligenes_denitrificans"_leifson_and_hugh_1954 "alcaligenes~~ denitrificans~~" leifson and hugh 1954~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A4C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Achromobacter_denitrificans Achromobacter denitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A4C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.45Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 "Alcaligenes denitrificans" Leifson and Hugh 1954])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [https://pdbe.org/1a4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [https://www.ebi.ac.uk/pdbsum/1a4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4c ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [https://pdbe.org/1a4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [https://www.ebi.ac.uk/pdbsum/1a4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~AZUR_ALCDE AZUR_ALCDE]~~] Transfers electrons from cytochrome c551 to cytochrome oxidase.	+	[https://www.uniprot.org/uniprot/AZUR_ACHDE AZUR_ACHDE] Transfers electrons from cytochrome c551 to cytochrome oxidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Alcaligenes~~ denitrificans ~~leifson and hugh 1954~~]]	+	[[Category: Achromobacter denitrificans]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Messerschmidt, A]]	+	[[Category: Messerschmidt A]]
-	[[Category: Prade, L]]	+	[[Category: Prade L]]
-	~~[[Category: Cuproprotein]]~~	+
-	~~[[Category: Electron transport~~]]	+

OCA at 14:35, 3 November 2021

OCA — Wed, 03 Nov 2021 14:35:31 GMT

←Older revision		Revision as of 14:35, 3 November 2021
Line 3:		Line 3:
	<StructureSection load='1a4c' size='340' side='right'caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>		<StructureSection load='1a4c' size='340' side='right'caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"alcaligenes_denitrificans"_leifson_and_hugh_1954 "alcaligenes denitrificans" leifson and hugh 1954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1A4C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"alcaligenes_denitrificans"_leifson_and_hugh_1954 "alcaligenes denitrificans" leifson and hugh 1954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A4C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 "Alcaligenes denitrificans" Leifson and Hugh 1954])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 "Alcaligenes denitrificans" Leifson and Hugh 1954])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [~~http~~://pdbe.org/1a4c PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1a4c PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4c ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [https://pdbe.org/1a4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [https://www.ebi.ac.uk/pdbsum/1a4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AZUR_ALCDE AZUR_ALCDE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.	+	[[https://www.uniprot.org/uniprot/AZUR_ALCDE AZUR_ALCDE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:07, 18 November 2020

OCA — Wed, 18 Nov 2020 10:07:43 GMT

←Older revision		Revision as of 10:07, 18 November 2020
Line 1:		Line 1:

	==AZURIN MUTANT WITH MET 121 REPLACED BY HIS, PH 3.5 CRYSTAL FORM, DATA COLLECTED AT-180 DEGREES CELSIUS==		==AZURIN MUTANT WITH MET 121 REPLACED BY HIS, PH 3.5 CRYSTAL FORM, DATA COLLECTED AT-180 DEGREES CELSIUS==
-	<StructureSection load='1a4c' size='340' side='right' caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>	+	<StructureSection load='1a4c' size='340' side='right'caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"alcaligenes_denitrificans"_leifson_and_hugh_1954 "alcaligenes denitrificans" leifson and hugh 1954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1A4C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"alcaligenes_denitrificans"_leifson_and_hugh_1954 "alcaligenes denitrificans" leifson and hugh 1954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1A4C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 "Alcaligenes denitrificans" Leifson and Hugh 1954])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 "Alcaligenes denitrificans" Leifson and Hugh 1954])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://pdbe.org/1a4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4c ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://pdbe.org/1a4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a4/1a4c_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a4/1a4c_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1a4c" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1a4c" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Azurin 3D structures\|Azurin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 34:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Alcaligenes denitrificans leifson and hugh 1954]]		[[Category: Alcaligenes denitrificans leifson and hugh 1954]]
		+	[[Category: Large Structures]]
	[[Category: Messerschmidt, A]]		[[Category: Messerschmidt, A]]
	[[Category: Prade, L]]		[[Category: Prade, L]]
	[[Category: Cuproprotein]]		[[Category: Cuproprotein]]
	[[Category: Electron transport]]		[[Category: Electron transport]]

OCA at 06:21, 29 November 2017

OCA — Wed, 29 Nov 2017 06:21:54 GMT

←Older revision		Revision as of 06:21, 29 November 2017
Line 3:		Line 3:
	<StructureSection load='1a4c' size='340' side='right' caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>		<StructureSection load='1a4c' size='340' side='right' caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A4C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"alcaligenes_denitrificans"_leifson_and_hugh_1954 "alcaligenes denitrificans" leifson and hugh 1954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A4C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 "Alcaligenes denitrificans" Leifson and Hugh 1954])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://pdbe.org/1a4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4c ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://pdbe.org/1a4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4c ProSAT]</span></td></tr>
	</table>		</table>
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1a4c" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1a4c" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Azurin\|Azurin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Alcaligenes denitrificans leifson and hugh 1954]]
	[[Category: Messerschmidt, A]]		[[Category: Messerschmidt, A]]
	[[Category: Prade, L]]		[[Category: Prade, L]]
	[[Category: Cuproprotein]]		[[Category: Cuproprotein]]
	[[Category: Electron transport]]		[[Category: Electron transport]]

OCA at 09:22, 9 August 2017

OCA — Wed, 09 Aug 2017 09:22:34 GMT

←Older revision		Revision as of 09:22, 9 August 2017
Line 1:		Line 1:
		+
	==AZURIN MUTANT WITH MET 121 REPLACED BY HIS, PH 3.5 CRYSTAL FORM, DATA COLLECTED AT-180 DEGREES CELSIUS==		==AZURIN MUTANT WITH MET 121 REPLACED BY HIS, PH 3.5 CRYSTAL FORM, DATA COLLECTED AT-180 DEGREES CELSIUS==
	<StructureSection load='1a4c' size='340' side='right' caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>		<StructureSection load='1a4c' size='340' side='right' caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/"alcaligenes_denitrificans"_leifson_and_hugh_1954 "alcaligenes denitrificans" leifson and hugh 1954]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A4C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A4C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 "Alcaligenes denitrificans" Leifson and Hugh 1954])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://pdbe.org/1a4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a4c ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://pdbe.org/1a4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a4c ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 35:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Alcaligenes denitrificans leifson and hugh 1954]]
	[[Category: Messerschmidt, A]]		[[Category: Messerschmidt, A]]
	[[Category: Prade, L]]		[[Category: Prade, L]]
	[[Category: Cuproprotein]]		[[Category: Cuproprotein]]
	[[Category: Electron transport]]		[[Category: Electron transport]]

OCA at 16:01, 9 September 2015

OCA — Wed, 09 Sep 2015 16:01:43 GMT

←Older revision		Revision as of 16:01, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='1a4c' size='340' side='right' caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>		<StructureSection load='1a4c' size='340' side='right' caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Achromobacter_denitrificans Achromobacter~~ denitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A4C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"alcaligenes_denitrificans"_leifson_and_hugh_1954 "alcaligenes denitrificans" leifson and hugh 1954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A4C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 ~~Achromobacter~~ denitrificans])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 "Alcaligenes denitrificans" Leifson and Hugh 1954])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://pdbe.org/1a4c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1a4c" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Achromobacter~~ denitrificans]]	+	[[Category: Alcaligenes denitrificans leifson and hugh 1954]]
	[[Category: Messerschmidt, A]]		[[Category: Messerschmidt, A]]
	[[Category: Prade, L]]		[[Category: Prade, L]]
	[[Category: Cuproprotein]]		[[Category: Cuproprotein]]
	[[Category: Electron transport]]		[[Category: Electron transport]]

OCA at 19:54, 25 December 2014

OCA — Thu, 25 Dec 2014 19:54:23 GMT

←Older revision		Revision as of 19:54, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AZUR_ALCDE AZUR_ALCDE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:17, 22 December 2014

OCA — Mon, 22 Dec 2014 10:17:28 GMT

←Older revision		Revision as of 10:17, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_denitrificans Achromobacter denitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A4C FirstGlance]. <br>		<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_denitrificans Achromobacter denitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A4C FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 Achromobacter denitrificans])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 Achromobacter denitrificans])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Achromobacter denitrificans]]		[[Category: Achromobacter denitrificans]]
-	[[Category: Messerschmidt, A.]]	+	[[Category: Messerschmidt, A]]
-	[[Category: Prade, L.]]	+	[[Category: Prade, L]]
	[[Category: Cuproprotein]]		[[Category: Cuproprotein]]
	[[Category: Electron transport]]		[[Category: Electron transport]]

OCA at 08:35, 23 July 2014

OCA — Wed, 23 Jul 2014 08:35:56 GMT

←Older revision		Revision as of 08:35, 23 July 2014
Line 1:		Line 1:
-	[[~~Image:~~1a4c.~~png~~\|~~left~~\|200px]]	+	==AZURIN MUTANT WITH MET 121 REPLACED BY HIS, PH 3.5 CRYSTAL FORM, DATA COLLECTED AT-180 DEGREES CELSIUS==
		+	<StructureSection load='1a4c' size='340' side='right' caption='[[1a4c]], [[Resolution\|resolution]] 2.45Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1a4c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_denitrificans Achromobacter denitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A4C FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AZU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32002 Achromobacter denitrificans])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a4c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a4c RCSB], [http://www.ebi.ac.uk/pdbsum/1a4c PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a4/1a4c_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The rack-induced bonding mechanism of metals to proteins is a useful concept for explaining the generation of metal sites in electron transfer proteins, such as the blue copper proteins, that are designed for rapid electron transfer. The trigonal pyramidal structure imposed by the protein with three strong equatorial ligands (one Cys and two His) provides a favorable geometry for both cuprous and cupric oxidation states. However, the crystal structures of the Met121His mutant of azurin from Alcaligenes denitrificans at pH 6.5 (1.89- and 1.91-A resolutions) and pH 3.5 (2.45-A resolution) show that the preformed metal binding cavity in the protein is more flexible than expected. At high pH (6.5), the Cu site retains the same three equatorial ligands as in the wild-type azurin and adds His121 as a fourth strong ligand, creating a tetrahedral copper site geometry with a green color referred to as 1.5 type. In the low pH (3.5) structure, the protonation of His121 causes a conformational change in residues 117-123, moving His121 away from the copper. The empty coordination site is occupied by an oxygen atom of a nitrate molecule of the buffer solution. This axial ligand is coordinated less strongly, generating a distorted tetrahedral copper geometry with a blue color and spectroscopic properties of a type-1 site. These crystal structures demonstrate that blue copper proteins are flexible enough to permit a range of movement of the Cu atom along the axial direction of the trigonal pyramid.

-	~~{{STRUCTURE_1a4c\| PDB=1a4c \| SCENE= }}~~	+	Rack-induced metal binding vs. flexibility: Met121His azurin crystal structures at different pH.,Messerschmidt A, Prade L, Kroes SJ, Sanders-Loehr J, Huber R, Canters GW Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3443-8. PMID:9520385<ref>PMID:9520385</ref>

-	~~===AZURIN MUTANT WITH MET 121 REPLACED BY HIS~~, ~~PH 3~~.~~5 CRYSTAL FORM, DATA COLLECTED AT-180 DEGREES CELSIUS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_9520385}}~~	+	==See Also==
-		+	*[[Azurin\|Azurin]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1a4c~~]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_denitrificans Achromobacter denitrificans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4C OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:009520385<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Achromobacter denitrificans]]		[[Category: Achromobacter denitrificans]]
	[[Category: Messerschmidt, A.]]		[[Category: Messerschmidt, A.]]

OCA: Protected "1a4c" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 12:18:04 GMT

Protected "1a4c" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:18, 21 October 2012