1a6m - Revision history

OCA at 10:48, 2 August 2023

OCA — Wed, 02 Aug 2023 10:48:08 GMT

←Older revision		Revision as of 10:48, 2 August 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A6M FirstGlance]. <br>		<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A6M FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [https://pdbe.org/1a6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [https://www.ebi.ac.uk/pdbsum/1a6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a6m ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [https://pdbe.org/1a6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [https://www.ebi.ac.uk/pdbsum/1a6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a6m ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	+	[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 39:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Physeter catodon]]		[[Category: Physeter catodon]]
-	[[Category: Berendzen, J]]	+	[[Category: Berendzen J]]
-	[[Category: Chu, K]]	+	[[Category: Chu K]]
-	[[Category: Schlichting, I]]	+	[[Category: Schlichting I]]
-	[[Category: Sweet~~, R M~~]]	+	[[Category: Sweet RM]]
-	[[Category: Vojtechovsky, J]]	+	[[Category: Vojtechovsky J]]
-	~~[[Category: Conformational substate]]~~	+
-	~~[[Category: Heme protein]]~~	+
-	~~[[Category: Ligand binding geometry]]~~	+
-	~~[[Category: Model compound]]~~	+
-	~~[[Category: Oxygen storage]]~~	+
-	~~[[Category: Oxygen transport~~]]	+

OCA at 10:17, 17 February 2021

OCA — Wed, 17 Feb 2021 10:17:16 GMT

←Older revision		Revision as of 10:17, 17 February 2021
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	<StructureSection load='1a6m' size='340' side='right'caption='[[1a6m]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='1a6m' size='340' side='right'caption='[[1a6m]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1A6M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A6M FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [~~http~~://pdbe.org/1a6m PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1a6m PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1a6m ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [https://pdbe.org/1a6m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [https://www.ebi.ac.uk/pdbsum/1a6m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a6m ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.	+	[[https://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	==See Also==		==See Also==
	*[[Myoglobin\|Myoglobin]]		*[[Myoglobin\|Myoglobin]]
-	*[[~~User:Michael Roberts/BIOL115 Myo~~\|~~User:Michael Roberts/BIOL115 Myo~~]]	+	*[[Myoglobin 3D structures\|Myoglobin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:58, 10 May 2019

OCA — Fri, 10 May 2019 14:58:27 GMT

←Older revision		Revision as of 14:58, 10 May 2019
Line 1:		Line 1:

	==OXY-MYOGLOBIN, ATOMIC RESOLUTION==		==OXY-MYOGLOBIN, ATOMIC RESOLUTION==
-	<StructureSection load='1a6m' size='340' side='right' caption='[[1a6m]], [[Resolution\|resolution]] 1.00Å' scene=''>	+	<StructureSection load='1a6m' size='340' side='right'caption='[[1a6m]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A6M FirstGlance]. <br>		<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A6M FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/1a6m_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/1a6m_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Elizeu Sandbox\|Elizeu Sandbox]]
	*[[Myoglobin\|Myoglobin]]		*[[Myoglobin\|Myoglobin]]
	*[[User:Michael Roberts/BIOL115 Myo\|User:Michael Roberts/BIOL115 Myo]]		*[[User:Michael Roberts/BIOL115 Myo\|User:Michael Roberts/BIOL115 Myo]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Physeter catodon]]		[[Category: Physeter catodon]]
	[[Category: Berendzen, J]]		[[Category: Berendzen, J]]

OCA at 09:20, 9 August 2017

OCA — Wed, 09 Aug 2017 09:20:20 GMT

←Older revision		Revision as of 09:20, 9 August 2017
Line 1:		Line 1:
		+
	==OXY-MYOGLOBIN, ATOMIC RESOLUTION==		==OXY-MYOGLOBIN, ATOMIC RESOLUTION==
	<StructureSection load='1a6m' size='340' side='right' caption='[[1a6m]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='1a6m' size='340' side='right' caption='[[1a6m]], [[Resolution\|resolution]] 1.00Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A6M FirstGlance]. <br>		<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A6M FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [http://pdbe.org/1a6m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [http://www.ebi.ac.uk/pdbsum/1a6m PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [http://pdbe.org/1a6m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [http://www.ebi.ac.uk/pdbsum/1a6m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a6m ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a6m ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 29:		Line 30:

	==See Also==		==See Also==
		+	*[[Elizeu Sandbox\|Elizeu Sandbox]]
	*[[Myoglobin\|Myoglobin]]		*[[Myoglobin\|Myoglobin]]
	*[[User:Michael Roberts/BIOL115 Myo\|User:Michael Roberts/BIOL115 Myo]]		*[[User:Michael Roberts/BIOL115 Myo\|User:Michael Roberts/BIOL115 Myo]]

OCA at 15:57, 9 September 2015

OCA — Wed, 09 Sep 2015 15:57:14 GMT

←Older revision		Revision as of 15:57, 9 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A6M FirstGlance]. <br>		<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A6M FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [http://www.ebi.ac.uk/pdbsum/1a6m PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [http://pdbe.org/1a6m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [http://www.ebi.ac.uk/pdbsum/1a6m PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1a6m" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 19:52, 25 December 2014

OCA — Thu, 25 Dec 2014 19:52:45 GMT

←Older revision		Revision as of 19:52, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [http://www.ebi.ac.uk/pdbsum/1a6m PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [http://www.ebi.ac.uk/pdbsum/1a6m PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:13, 22 December 2014

OCA — Mon, 22 Dec 2014 10:13:09 GMT

←Older revision		Revision as of 10:13, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A6M FirstGlance]. <br>		<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A6M FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [http://www.ebi.ac.uk/pdbsum/1a6m PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [http://www.ebi.ac.uk/pdbsum/1a6m PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Physeter catodon]]		[[Category: Physeter catodon]]
-	[[Category: Berendzen, J.]]	+	[[Category: Berendzen, J]]
-	[[Category: Chu, K.]]	+	[[Category: Chu, K]]
-	[[Category: Schlichting, I.]]	+	[[Category: Schlichting, I]]
-	[[Category: Sweet, R M.]]	+	[[Category: Sweet, R M]]
-	[[Category: Vojtechovsky, J.]]	+	[[Category: Vojtechovsky, J]]
	[[Category: Conformational substate]]		[[Category: Conformational substate]]
	[[Category: Heme protein]]		[[Category: Heme protein]]

OCA at 08:33, 23 July 2014

OCA — Wed, 23 Jul 2014 08:33:47 GMT

←Older revision		Revision as of 08:33, 23 July 2014
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-	[[~~Image~~:1a6m.~~png\|left~~\|200px]]	+	==OXY-MYOGLOBIN, ATOMIC RESOLUTION==
		+	<StructureSection load='1a6m' size='340' side='right' caption='[[1a6m]], [[Resolution\|resolution]] 1.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A6M FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a6m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a6m RCSB], [http://www.ebi.ac.uk/pdbsum/1a6m PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/1a6m_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have used x-ray crystallography to determine the structures of sperm whale myoglobin (Mb) in four different ligation states (unligated, ferric aquomet, oxygenated, and carbonmonoxygenated) to a resolution of better than 1.2 A. Data collection and analysis were performed in as much the same way as possible to reduce model bias in differences between structures. The structural differences among the ligation states are much smaller than previously estimated, with differences of <0.25 A root-mean-square deviation among all atoms. One structural parameter previously thought to vary among the ligation states, the proximal histidine (His-93) azimuthal angle, is nearly identical in all the ferrous complexes, although the tilt of the proximal histidine is different in the unligated form. There are significant differences, however, in the heme geometry, in the position of the heme in the pocket, and in the distal histidine (His-64) conformations. In the CO complex the majority conformation of ligand is at an angle of 18 +/- 3 degrees with respect to the heme plane, with a geometry similar to that seen in encumbered model compounds; this angle is significantly smaller than reported previously by crystallographic studies on monoclinic Mb crystals, but still significantly larger than observed by photoselection. The distal histidine in unligated Mb and in the dioxygenated complex is best described as having two conformations. Two similar conformations are observed in MbCO, in addition to another conformation that has been seen previously in low-pH structures where His-64 is doubly protonated. We suggest that these conformations of the distal histidine correspond to the different conformational substates of MbCO and MbO(2) seen in vibrational spectra. Full-matrix refinement provides uncertainty estimates of important structural parameters. Anisotropic refinement yields information about correlated disorder of atoms; we find that the proximal (F) helix and heme move approximately as rigid bodies, but that the distal (E) helix does not.

-	~~{{STRUCTURE_1a6m\| PDB=1a6m \| SCENE= }}~~	+	Crystal structures of myoglobin-ligand complexes at near-atomic resolution.,Vojtechovsky J, Chu K, Berendzen J, Sweet RM, Schlichting I Biophys J. 1999 Oct;77(4):2153-74. PMID:10512835<ref>PMID:10512835</ref>

-	~~===OXY-MYOGLOBIN~~, ~~ATOMIC RESOLUTION===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10512835}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1a6m]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Physeter_catodon Physeter catodon]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA].~~	+

	==See Also==		==See Also==
	*[[Myoglobin\|Myoglobin]]		*[[Myoglobin\|Myoglobin]]
-		+	*[[User:Michael Roberts/BIOL115 Myo\|User:Michael Roberts/BIOL115 Myo]]
-	==~~Reference~~==	+	== References ==
-	<~~ref group="xtra">PMID:010512835<~~/~~ref~~><~~ref group="xtra">PMID:011917145</ref><ref group="xtra">PMID:018754631</ref><references group="xtra"~~/>	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Physeter catodon]]		[[Category: Physeter catodon]]
	[[Category: Berendzen, J.]]		[[Category: Berendzen, J.]]

OCA at 20:47, 20 October 2012

OCA — Sat, 20 Oct 2012 20:47:07 GMT

←Older revision		Revision as of 20:47, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1a6m]] is a 1 chain structure ~~of [[Myoglobin]]~~ with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA].	+	[[1a6m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6M OCA].

	==See Also==		==See Also==

OCA at 11:36, 27 July 2012

OCA — Fri, 27 Jul 2012 11:36:43 GMT

←Older revision		Revision as of 11:36, 27 July 2012
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	[[Image:1a6m.png\|left\|200px]]		[[Image:1a6m.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1a6m\| PDB=1a6m \| SCENE= }}		{{STRUCTURE_1a6m\| PDB=1a6m \| SCENE= }}

	===OXY-MYOGLOBIN, ATOMIC RESOLUTION===		===OXY-MYOGLOBIN, ATOMIC RESOLUTION===

-
-	<!--
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	==See Also==		==See Also==
-	*[[Myoglobin]]	+	*[[Myoglobin\|Myoglobin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~10512835~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:010512835</ref><ref group="xtra">PMID:011917145</ref><ref group="xtra">PMID:018754631</ref><references group="xtra"/>
	[[Category: Physeter catodon]]		[[Category: Physeter catodon]]
	[[Category: Berendzen, J.]]		[[Category: Berendzen, J.]]