1atg - Revision history

OCA at 06:33, 7 February 2024

OCA — Wed, 07 Feb 2024 06:33:10 GMT

←Older revision		Revision as of 06:33, 7 February 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ATG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ATG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [https://pdbe.org/1atg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [https://www.ebi.ac.uk/pdbsum/1atg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1atg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [https://pdbe.org/1atg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [https://www.ebi.ac.uk/pdbsum/1atg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1atg ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q7SIH2_AZOVI Q7SIH2_AZOVI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1atg ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1atg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Background:. Periplasmic receptors constitute a diverse class of binding proteins that differ widely in size, sequence and ligand specificity. Nevertheless, almost all of them display a common beta/alpha folding motif and have similar tertiary structures consisting of two globular domains. The ligand is bound at the bottom of a deep cleft, which lies at the interface between these two domains. The oxyanion-binding proteins are notable in that they can discriminate between very similar ligands. Results:. Azotobacter vinelandii is unusual in that it possesses two periplasmic molybdate-binding proteins. The crystal structure of one of these with bound ligand has been determined at 1.2 A resolution. It superficially resembles the structure of sulphate-binding protein (SBP) from Salmonella typhimurium and uses a similar constellation of hydrogen-bonding interactions to bind its ligand. However, the detailed interactions are distinct from those of SBP and the more closely related molybdate-binding protein of Escherichia coli. Conclusions:. Despite differences in the residues involved in binding, the volumes of the binding pockets in the A. vinelandii and E. coli molybdate-binding proteins are similar and are significantly larger than that of SBP. We conclude that the discrimination between molybdate and sulphate shown by these binding proteins is largely dependent upon small differences in the sizes of these two oxyanions.
-
-	Ligand size is a major determinant of specificity in periplasmic oxyanion-binding proteins: the 1.2 A resolution crystal structure of Azotobacter vinelandii ModA.,Lawson DM, Williams CE, Mitchenall LA, Pau RN Structure. 1998 Dec 15;6(12):1529-39. PMID:9862806<ref>PMID:9862806</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1atg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[ABC transporter 3D structures\|ABC transporter 3D structures]]		*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	*[[ModG\|ModG]]		*[[ModG\|ModG]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Azotobacter vinelandii]]		[[Category: Azotobacter vinelandii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Lawson~~, D M~~]]	+	[[Category: Lawson DM]]
-	[[Category: Mitchenall~~, L A~~]]	+	[[Category: Mitchenall LA]]
-	[[Category: Pau~~, R N~~]]	+	[[Category: Pau RN]]
-	[[Category: Williams~~, C E.M]]~~	+	[[Category: Williams CEM]]
-	~~[[Category: Abc transporter]]~~	+
-	~~[[Category: Binding protein]]~~	+
-	~~[[Category: Molybdate]]~~	+
-	~~[[Category: Periplasm]]~~	+
-	~~[[Category: Tungstate~~]]	+

OCA at 09:48, 26 May 2021

OCA — Wed, 26 May 2021 09:48:39 GMT

←Older revision		Revision as of 09:48, 26 May 2021
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	<StructureSection load='1atg' size='340' side='right'caption='[[1atg]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='1atg' size='340' side='right'caption='[[1atg]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ATG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ATG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [~~http~~://pdbe.org/1atg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1atg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1atg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [https://pdbe.org/1atg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [https://www.ebi.ac.uk/pdbsum/1atg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1atg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 28:		Line 28:

	==See Also==		==See Also==
		+	*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	*[[ModG\|ModG]]		*[[ModG\|ModG]]
	== References ==		== References ==

OCA at 07:11, 21 August 2019

OCA — Wed, 21 Aug 2019 07:11:24 GMT

←Older revision		Revision as of 07:11, 21 August 2019
Line 1:		Line 1:

	==AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN==		==AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN==
-	<StructureSection load='1atg' size='340' side='right' caption='[[1atg]], [[Resolution\|resolution]] 1.20Å' scene=''>	+	<StructureSection load='1atg' size='340' side='right'caption='[[1atg]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ATG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ATG FirstGlance]. <br>
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/1atg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/1atg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1atg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1atg" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[ModG\|ModG]]
	== References ==		== References ==
	<references/>		<references/>
Line 31:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Azotobacter vinelandii]]		[[Category: Azotobacter vinelandii]]
		+	[[Category: Large Structures]]
	[[Category: Lawson, D M]]		[[Category: Lawson, D M]]
	[[Category: Mitchenall, L A]]		[[Category: Mitchenall, L A]]

OCA at 10:38, 15 November 2017

OCA — Wed, 15 Nov 2017 10:38:50 GMT

←Older revision		Revision as of 10:38, 15 November 2017
Line 1:		Line 1:
		+
	==AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN==		==AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN==
	<StructureSection load='1atg' size='340' side='right' caption='[[1atg]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='1atg' size='340' side='right' caption='[[1atg]], [[Resolution\|resolution]] 1.20Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ATG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ATG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [http://pdbe.org/1atg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [http://www.ebi.ac.uk/pdbsum/1atg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [http://pdbe.org/1atg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [http://www.ebi.ac.uk/pdbsum/1atg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1atg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</div>		</div>
	<div class="pdbe-citations 1atg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1atg" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[ModG\|ModG]]
	== References ==		== References ==
	<references/>		<references/>
Line 40:		Line 38:
	[[Category: Binding protein]]		[[Category: Binding protein]]
	[[Category: Molybdate]]		[[Category: Molybdate]]
		+	[[Category: Periplasm]]
	[[Category: Tungstate]]		[[Category: Tungstate]]

OCA at 12:44, 8 February 2016

OCA — Mon, 08 Feb 2016 12:44:16 GMT

←Older revision		Revision as of 12:44, 8 February 2016
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1atg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:42, 10 September 2015

OCA — Thu, 10 Sep 2015 11:42:23 GMT

←Older revision		Revision as of 11:42, 10 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ATG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ATG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [http://www.ebi.ac.uk/pdbsum/1atg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [http://pdbe.org/1atg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [http://www.ebi.ac.uk/pdbsum/1atg PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1atg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 10:39, 22 December 2014

OCA — Mon, 22 Dec 2014 10:39:23 GMT

←Older revision		Revision as of 10:39, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ATG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ATG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [http://www.ebi.ac.uk/pdbsum/1atg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [http://www.ebi.ac.uk/pdbsum/1atg PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Azotobacter vinelandii]]		[[Category: Azotobacter vinelandii]]
-	[[Category: Lawson, D M.]]	+	[[Category: Lawson, D M]]
-	[[Category: Mitchenall, L A.]]	+	[[Category: Mitchenall, L A]]
-	[[Category: Pau, R N.]]	+	[[Category: Pau, R N]]
-	[[Category: Williams, C E.M.]]	+	[[Category: Williams, C E.M]]
	[[Category: Abc transporter]]		[[Category: Abc transporter]]
	[[Category: Binding protein]]		[[Category: Binding protein]]
	[[Category: Molybdate]]		[[Category: Molybdate]]
	[[Category: Tungstate]]		[[Category: Tungstate]]

OCA at 08:09, 30 July 2014

OCA — Wed, 30 Jul 2014 08:09:56 GMT

←Older revision		Revision as of 08:09, 30 July 2014
Line 1:		Line 1:
-	[[~~Image~~:1atg.~~png\|left~~\|200px]]	+	==AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN==
		+	<StructureSection load='1atg' size='340' side='right' caption='[[1atg]], [[Resolution\|resolution]] 1.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ATG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [http://www.ebi.ac.uk/pdbsum/1atg PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/1atg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Background:. Periplasmic receptors constitute a diverse class of binding proteins that differ widely in size, sequence and ligand specificity. Nevertheless, almost all of them display a common beta/alpha folding motif and have similar tertiary structures consisting of two globular domains. The ligand is bound at the bottom of a deep cleft, which lies at the interface between these two domains. The oxyanion-binding proteins are notable in that they can discriminate between very similar ligands. Results:. Azotobacter vinelandii is unusual in that it possesses two periplasmic molybdate-binding proteins. The crystal structure of one of these with bound ligand has been determined at 1.2 A resolution. It superficially resembles the structure of sulphate-binding protein (SBP) from Salmonella typhimurium and uses a similar constellation of hydrogen-bonding interactions to bind its ligand. However, the detailed interactions are distinct from those of SBP and the more closely related molybdate-binding protein of Escherichia coli. Conclusions:. Despite differences in the residues involved in binding, the volumes of the binding pockets in the A. vinelandii and E. coli molybdate-binding proteins are similar and are significantly larger than that of SBP. We conclude that the discrimination between molybdate and sulphate shown by these binding proteins is largely dependent upon small differences in the sizes of these two oxyanions.

-	~~{{STRUCTURE_1atg\| PDB=1atg \| SCENE= }}~~	+	Ligand size is a major determinant of specificity in periplasmic oxyanion-binding proteins: the 1.2 A resolution crystal structure of Azotobacter vinelandii ModA.,Lawson DM, Williams CE, Mitchenall LA, Pau RN Structure. 1998 Dec 15;6(12):1529-39. PMID:9862806<ref>PMID:9862806</ref>

-	~~===AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9862806}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1atg]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA].~~	+

	==See Also==		==See Also==
	*[[ModG\|ModG]]		*[[ModG\|ModG]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:009862806<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Azotobacter vinelandii]]		[[Category: Azotobacter vinelandii]]
	[[Category: Lawson, D M.]]		[[Category: Lawson, D M.]]

OCA at 10:10, 20 October 2012

OCA — Sat, 20 Oct 2012 10:10:25 GMT

←Older revision		Revision as of 10:10, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1atg]] is a 1 chain structure ~~of [[ModG]]~~ with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA].	+	[[1atg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA].

	==See Also==		==See Also==

OCA: Protected "1atg" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 01:14:10 GMT

Protected "1atg" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:14, 26 July 2012