1b01 - Revision history

OCA at 23:18, 27 December 2023

OCA — Wed, 27 Dec 2023 23:18:04 GMT

←Older revision		Revision as of 23:18, 27 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B01 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B01 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [https://pdbe.org/1b01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [https://www.ebi.ac.uk/pdbsum/1b01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b01 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.56Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [https://pdbe.org/1b01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [https://www.ebi.ac.uk/pdbsum/1b01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b01 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 11:17, 30 November 2022

OCA — Wed, 30 Nov 2022 11:17:35 GMT

←Older revision		Revision as of 11:17, 30 November 2022
Line 3:		Line 3:
	<StructureSection load='1b01' size='340' side='right'caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>		<StructureSection load='1b01' size='340' side='right'caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B01 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B01 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [https://pdbe.org/1b01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [https://www.ebi.ac.uk/pdbsum/1b01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b01 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [https://pdbe.org/1b01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [https://www.ebi.ac.uk/pdbsum/1b01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b01 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/COPG_STRAG COPG_STRAG]] Regulates the plasmid copy number. Binds to the RepAB promoter thus controlling the synthesis of the plasmid replication initiator protein RepB.<ref>PMID:2497439</ref> <ref>PMID:2373704</ref>	+	[https://www.uniprot.org/uniprot/COPG_STRAG COPG_STRAG] Regulates the plasmid copy number. Binds to the RepAB promoter thus controlling the synthesis of the plasmid replication initiator protein RepB.<ref>PMID:2497439</ref> <ref>PMID:2373704</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Acebo, P]]	+	[[Category: Streptococcus agalactiae]]
-	[[Category: Coll, M]]	+	[[Category: Acebo P]]
-	[[Category: Eritja, R]]	+	[[Category: Coll M]]
-	[[Category: Espinosa, M]]	+	[[Category: Eritja R]]
-	[[Category: Gomis-Rueth~~, F X~~]]	+	[[Category: Espinosa M]]
-	[[Category: Gonzalez, A]]	+	[[Category: Gomis-Rueth FX]]
-	[[Category: Guasch, A]]	+	[[Category: Gonzalez A]]
-	[[Category: Parraga, A]]	+	[[Category: Guasch A]]
-	[[Category: Sola, M]]	+	[[Category: Parraga A]]
-	[[Category: Solar, G ~~del]]~~	+	[[Category: Sola M]]
-	~~[[Category: Dna-binding protein]]~~	+	[[Category: Del Solar G]]
-	~~[[Category: Gene regulation-dna complex]]~~	+
-	~~[[Category: Gene regulation/dna]]~~	+
-	~~[[Category: Plasmid]]~~	+
-	~~[[Category: Protein-dna complex]]~~	+
-	~~[[Category: Transcriptional repressor~~]]	+

OCA at 06:55, 24 February 2021

OCA — Wed, 24 Feb 2021 06:55:48 GMT

←Older revision		Revision as of 06:55, 24 February 2021
Line 3:		Line 3:
	<StructureSection load='1b01' size='340' side='right'caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>		<StructureSection load='1b01' size='340' side='right'caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1B01 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B01 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [~~http~~://pdbe.org/1b01 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1b01 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1b01 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [https://pdbe.org/1b01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [https://www.ebi.ac.uk/pdbsum/1b01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b01 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/COPG_STRAG COPG_STRAG]] Regulates the plasmid copy number. Binds to the RepAB promoter thus controlling the synthesis of the plasmid replication initiator protein RepB.<ref>PMID:2497439</ref> <ref>PMID:2373704</ref>	+	[[https://www.uniprot.org/uniprot/COPG_STRAG COPG_STRAG]] Regulates the plasmid copy number. Binds to the RepAB promoter thus controlling the synthesis of the plasmid replication initiator protein RepB.<ref>PMID:2497439</ref> <ref>PMID:2373704</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 09:23, 21 May 2019

OCA — Tue, 21 May 2019 09:23:04 GMT

←Older revision		Revision as of 09:23, 21 May 2019
Line 1:		Line 1:

	==TRANSCRIPTIONAL REPRESSOR COPG/DNA COMPLEX==		==TRANSCRIPTIONAL REPRESSOR COPG/DNA COMPLEX==
-	<StructureSection load='1b01' size='340' side='right' caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>	+	<StructureSection load='1b01' size='340' side='right'caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B01 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B01 FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Acebo, P]]		[[Category: Acebo, P]]
	[[Category: Coll, M]]		[[Category: Coll, M]]

OCA at 06:15, 17 August 2017

OCA — Thu, 17 Aug 2017 06:15:03 GMT

←Older revision		Revision as of 06:15, 17 August 2017
Line 1:		Line 1:
		+
	==TRANSCRIPTIONAL REPRESSOR COPG/DNA COMPLEX==		==TRANSCRIPTIONAL REPRESSOR COPG/DNA COMPLEX==
	<StructureSection load='1b01' size='340' side='right' caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>		<StructureSection load='1b01' size='340' side='right' caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/"streptoccocus_de_la_mammite"_nocard_and_mollereau_1887 "streptoccocus de la mammite" nocard and mollereau 1887]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B01 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B01 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [http://pdbe.org/1b01 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [http://www.ebi.ac.uk/pdbsum/1b01 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [http://pdbe.org/1b01 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [http://www.ebi.ac.uk/pdbsum/1b01 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1b01 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Streptoccocus de la mammite nocard and mollereau 1887]]
	[[Category: Acebo, P]]		[[Category: Acebo, P]]
	[[Category: Coll, M]]		[[Category: Coll, M]]
Line 34:		Line 34:
	[[Category: Gene regulation-dna complex]]		[[Category: Gene regulation-dna complex]]
	[[Category: Gene regulation/dna]]		[[Category: Gene regulation/dna]]
		+	[[Category: Plasmid]]
	[[Category: Protein-dna complex]]		[[Category: Protein-dna complex]]
	[[Category: Transcriptional repressor]]		[[Category: Transcriptional repressor]]

OCA at 23:26, 11 September 2015

OCA — Fri, 11 Sep 2015 23:26:47 GMT

←Older revision		Revision as of 23:26, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1b01' size='340' side='right' caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>		<StructureSection load='1b01' size='340' side='right' caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_agalactiae Streptococcus agalactiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B01 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptoccocus_de_la_mammite"_nocard_and_mollereau_1887 "streptoccocus de la mammite" nocard and mollereau 1887]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B01 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [http://www.ebi.ac.uk/pdbsum/1b01 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [http://pdbe.org/1b01 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [http://www.ebi.ac.uk/pdbsum/1b01 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1b01" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptococcus agalactiae~~]]	+	[[Category: Streptoccocus de la mammite nocard and mollereau 1887]]
	[[Category: Acebo, P]]		[[Category: Acebo, P]]
	[[Category: Coll, M]]		[[Category: Coll, M]]

OCA at 20:49, 25 December 2014

OCA — Thu, 25 Dec 2014 20:49:53 GMT

←Older revision		Revision as of 20:49, 25 December 2014
Line 5:		Line 5:
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [http://www.ebi.ac.uk/pdbsum/1b01 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [http://www.ebi.ac.uk/pdbsum/1b01 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/COPG_STRAG COPG_STRAG]] Regulates the plasmid copy number. Binds to the RepAB promoter thus controlling the synthesis of the plasmid replication initiator protein RepB.<ref>PMID:2497439</ref> <ref>PMID:2373704</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 12:06, 22 December 2014

OCA — Mon, 22 Dec 2014 12:06:26 GMT

←Older revision		Revision as of 12:06, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B01 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B01 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [http://www.ebi.ac.uk/pdbsum/1b01 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [http://www.ebi.ac.uk/pdbsum/1b01 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	</StructureSection>		</StructureSection>
	[[Category: Streptococcus agalactiae]]		[[Category: Streptococcus agalactiae]]
-	[[Category: Acebo, P.]]	+	[[Category: Acebo, P]]
-	[[Category: Coll, M.]]	+	[[Category: Coll, M]]
-	[[Category: Eritja, R.]]	+	[[Category: Eritja, R]]
-	[[Category: Espinosa, M.]]	+	[[Category: Espinosa, M]]
-	[[Category: Gomis-Rueth, F X.]]	+	[[Category: Gomis-Rueth, F X]]
-	[[Category: Gonzalez, A.]]	+	[[Category: Gonzalez, A]]
-	[[Category: Guasch, A.]]	+	[[Category: Guasch, A]]
-	[[Category: Parraga, A.]]	+	[[Category: Parraga, A]]
-	[[Category: Sola, M.]]	+	[[Category: Sola, M]]
-	[[Category: Solar, G del.]]	+	[[Category: Solar, G del]]
	[[Category: Dna-binding protein]]		[[Category: Dna-binding protein]]
	[[Category: Gene regulation-dna complex]]		[[Category: Gene regulation-dna complex]]

OCA at 03:22, 7 August 2014

OCA — Thu, 07 Aug 2014 03:22:16 GMT

←Older revision		Revision as of 03:22, 7 August 2014
Line 1:		Line 1:
-	[[~~Image~~:1b01.~~png\|left\|200px~~]]	+	==TRANSCRIPTIONAL REPRESSOR COPG/DNA COMPLEX==
		+	<StructureSection load='1b01' size='340' side='right' caption='[[1b01]], [[Resolution\|resolution]] 2.56Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1b01]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B01 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b01 RCSB], [http://www.ebi.ac.uk/pdbsum/1b01 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structure of the 45 amino acid transcriptional repressor, CopG, has been solved unliganded and bound to its target operator DNA. The protein, encoded by the promiscuous streptococcal plasmid pMV158, is involved in the control of plasmid copy number. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. It is the prototype for a family of homologous plasmid repressors. CopG cooperatively associates, completely protecting several turns on one face of the double helix in both directions from a 13-bp pseudosymmetric primary DNA recognition element. In the complex structure, one protein tetramer binds at one face of a 19-bp oligonucleotide, containing the pseudosymmetric element, with two beta-ribbons inserted into the major groove. The DNA is bent 60 degrees by compression of both major and minor grooves. The protein dimer displays topological similarity to Arc and MetJ repressors. Nevertheless, the functional tetramer has a unique structure with the two vicinal recognition ribbon elements at a short distance, thus inducing strong DNA bend. Further structural resemblance is found with helix-turn-helix regions of unrelated DNA-binding proteins. In contrast to these, however, the bihelical region of CopG has a role in oligomerization instead of DNA recognition. This observation unveils an evolutionary link between ribbon-helix-helix and helix-turn-helix proteins.

-	~~{{STRUCTURE_1b01\| PDB=1b01 \| SCENE= }}~~	+	The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator.,Gomis-Ruth FX, Sola M, Acebo P, Parraga A, Guasch A, Eritja R, Gonzalez A, Espinosa M, del Solar G, Coll M EMBO J. 1998 Dec 15;17(24):7404-15. PMID:9857196<ref>PMID:9857196</ref>

-	~~===TRANSCRIPTIONAL REPRESSOR COPG~~/~~DNA COMPLEX===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9857196}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1b01]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptococcus_agalactiae Streptococcus agalactiae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1B01 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:009857196<~~/~~ref~~><~~ref group="xtra">PMID:015048824</ref><references group="xtra"~~/>	+
	[[Category: Streptococcus agalactiae]]		[[Category: Streptococcus agalactiae]]
	[[Category: Acebo, P.]]		[[Category: Acebo, P.]]

OCA: Protected "1b01" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 12:18:52 GMT

Protected "1b01" [edit=sysop:move=sysop]

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Revision as of 12:18, 21 October 2012